Shewanella sp. H8: ABIS04_04965
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Entry
ABIS04_04965 CDS
T10623
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sheh Shewanella sp. H8
Pathway
sheh00260
Glycine, serine and threonine metabolism
sheh00261
Monobactam biosynthesis
sheh00270
Cysteine and methionine metabolism
sheh00300
Lysine biosynthesis
sheh01100
Metabolic pathways
sheh01110
Biosynthesis of secondary metabolites
sheh01120
Microbial metabolism in diverse environments
sheh01230
Biosynthesis of amino acids
Module
sheh_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sheh_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sheh_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sheh00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ABIS04_04965 (thrA)
00270 Cysteine and methionine metabolism
ABIS04_04965 (thrA)
00300 Lysine biosynthesis
ABIS04_04965 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ABIS04_04965 (thrA)
Enzymes [BR:
sheh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ABIS04_04965 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ABIS04_04965 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Arm_2
DUF1131
Motif
Other DBs
NCBI-ProteinID:
XBJ49532
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All DBs
Position
1129252..1131720
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AA seq
822 aa
AA seq
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MKVMKFGGTSLANWPRFSMAADIIADTASTESVATVLSAPATVTNALLEMVDIAVNQQDY
QPVLDHINGVFSGLFSDAATSLITVAQHTLLVNKLAAQMQVWKDKLYGIKLLGECPDSVR
AELVVTGERLSAALMEQVMLAKGITSAQLDPVALFLAHGQPLESVVDITVSKPRFALLPL
DQYRVWVMPGFTAADAHGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV
VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQYQIPCYIKNSFNPSAPGTLVSDDD
DKTGLQVKAISNLDNQTMFNVSGPGMKGMVGMASRTLAVISRSGISVSLITQSSSEYSIS
FCVSTSQANKAKWALEQEFELELKSELLEPIELRQDLAIVSLIGDGMKTHKGVAAKFFTA
LAKASVNIIAIAQGSSERSISTVIQQKKTKHAIGACHQAFFDVQQYLDVFLVGSGNVGAG
LLEQIKQQSAMLKEQHISIRVCGIANSSQMLLNSEGLELNEWQSLLAEKGQPYDLAHLLE
WGQEQQLLNPVLVDCTSSELVSDRYLDVMNAGFHVVTPNKKSNTRDYAYYQALRHTALTQ
RRQFLYETTVGAGLPVIDNLKKLMYAGDKLHKFNGILSGSLSYIFGMLDEGMSLSQATAI
ARDKCFTEPDPRDDLSGMDVARKVLILAREVGLPLELEDINIESVLPADFDDSGDVNQFM
ANLPSLDAEISARVAAAKAEGKVLRYVGQIEEGQCHVRIIEVDASDPLYSVKGGENALAF
YSRYYQPIPFVLRGYGAGTDVTAAGAFADVLRTLNWTREVGL
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtaatgaaatttggtggaacatcgttggcgaactggcctcgtttttcgatggcg
gcagacattattgctgatacagcttcgacagaatctgttgctacggtactttctgctcct
gcaacagtaaccaatgcgctgttagagatggttgatattgctgtgaatcaacaagactat
cagccagtgttagaccacatcaatggtgtatttagtggtttattttctgatgctgcaaca
tcacttattacagtcgctcaacatacattactggttaataaattagctgcgcaaatgcaa
gtttggaaagataagctttatggcataaagttattgggcgaatgtcctgatagtgttcgt
gctgaattagtggtgactggcgaacgcttatcagcagcattaatggaacaagttatgcta
gcaaaaggcataacatcagcacaattagatccagtggccttatttttagctcatggacag
ccattagagtcggtagttgatattacagtgagcaaaccaaggttcgctttgttgccactt
gatcagtaccgagtttgggtgatgcctggatttaccgctgcagatgcacatggcaaagta
gtgacattaggccgtaacggttctgactattccgctgctgttttagcggcttgtttagac
gcttcaagttgtgaaatttggactgatgttgatggggtttacaatacggatcctcgtgta
gtagctgatgctaaattattgtcgcaattaagctatcaagaagcgatggagctctcttac
tttggcgccaaagtgttgcaccctaaaacgattgcacccattgcccaatatcaaattcct
tgttatatcaaaaacagttttaatccatcagctcccggcacattggtgtctgatgatgat
gataaaacgggtttacaagttaaagcaatttcaaatctagacaatcaaaccatgtttaac
gtctctggcccaggaatgaaaggcatggtcggtatggcaagtcggactttggcggttatc
tctcgcagtggtatctcggtgtcgcttattacccaaagctcatctgaatacagcatcagt
ttttgtgtctcaacctctcaagcgaacaaagcaaaatgggcactagagcaagaatttgaa
cttgagcttaaaagtgaattacttgaaccgattgaattgcgtcaagatttggcgatcgtg
tctttgattggcgatggtatgaaaactcacaagggagtagcggctaaattttttactgca
ctagctaaggccagcgtaaatatcattgctattgcacagggatcatcagaaagatcaatt
tctaccgttattcaacagaaaaaaaccaagcatgccattggtgcatgtcatcaagcattt
ttcgatgtacagcaatatctagatgtgtttttagtcggcagtggtaatgtcggtgctgga
ttattagagcaaattaaacaacaaagtgcgatgttaaaagaacagcacattagtattcgt
gtatgtgggatcgctaattcgagtcaaatgttattaaacagcgaaggacttgaactgaat
gagtggcaatcgttattggctgaaaaaggtcaaccgtatgatttagctcatttactcgag
tggggtcaagagcaacaattgcttaaccctgtgttagttgattgtacttcaagtgagttg
gtgtcagatcgttatcttgatgtgatgaatgccggtttccatgttgtcactcctaacaaa
aaatcaaacactcgtgattacgcttactatcaggcattgcgtcatacggcattaactcaa
cgtcgccaatttttgtatgaaacaactgtcggagcgggtttaccagttatcgacaacttg
aaaaaactgatgtatgccggtgataaactccataaattcaatggtattttatcaggttcg
ctatcgtatatttttggaatgttagatgaaggcatgagcttgtcgcaggcgacggcaatt
gctcgcgacaagtgttttaccgaacccgatcctcgtgatgatcttagtggtatggatgtc
gcacgtaaagtcctcattctcgctcgtgaagttggccttccattagagcttgaagacatt
aatattgaatcagtattgcctgctgactttgatgactctggcgatgtaaaccaatttatg
gcaaatcttccttcattggatgctgaaatctcagcccgagtcgcagcggccaaagccgaa
ggcaaggtattgcgttatgttggtcaaattgaagaggggcaatgtcatgtcagaattatt
gaagtggatgcctccgacccgttatacagtgtaaaaggtggcgagaatgccttggcattt
tatagtcgttattatcaaccaatcccttttgtgttaagagggtatggcgcaggtactgat
gtcactgctgctggagcgtttgctgacgtgttaagaaccctaaactggactcgtgaggtt
gggttatga
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