Shewanella sp. LZH-2: JM642_05820
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Entry
JM642_05820 CDS
T10525
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
shel Shewanella sp. LZH-2
Pathway
shel00260
Glycine, serine and threonine metabolism
shel00261
Monobactam biosynthesis
shel00270
Cysteine and methionine metabolism
shel00300
Lysine biosynthesis
shel01100
Metabolic pathways
shel01110
Biosynthesis of secondary metabolites
shel01120
Microbial metabolism in diverse environments
shel01230
Biosynthesis of amino acids
Module
shel_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
shel_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
shel_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
shel00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
JM642_05820 (thrA)
00270 Cysteine and methionine metabolism
JM642_05820 (thrA)
00300 Lysine biosynthesis
JM642_05820 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
JM642_05820 (thrA)
Enzymes [BR:
shel01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
JM642_05820 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
JM642_05820 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
DUF1131
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-ProteinID:
QRK80616
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All DBs
Position
1291641..1294109
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AA seq
822 aa
AA seq
DB search
MKVMKFGGTSLANWQRFSMAADIVAKAAKAEPVATVLSAPATVTNALLEMVDVAVKGEDY
SPVIQHVERVFTSLYQDAVSSGLSSSQSEVLFAGLSAQLARWQDRLRGITLLQECPDGVR
AEIVVAGERLSAALMEQVMLAKGITSAQLDPRELFLGRGRPLESVVDIAVSKPRFKNLAL
DEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV
VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA
DESGLQVKAISNLDNQTMFDVSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSIS
FCVATSESAKVKSALEQEFELEIKSDLLEPIAMRHDLAIVSLIGDGMRTHKGVAARFFQA
LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG
LLEQIKQQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADSQQPSDIPALLA
WVKEQQLLNPVLVDCTSSDQVSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQ
RRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGKLDEGMSLSEATKL
AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELNDIVVDSVLPAGFDDSGDVESFM
ARLPEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAF
YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtgatgaaatttggtggtacctcgcttgcaaattggcagcgattttcaatggcg
gcggatattgttgccaaggcagcgaaagctgagccggtcgcgacagtgctctctgcgcct
gcaacagtgacaaacgctctgctagaaatggtcgatgtggcggtgaaaggggaagattat
tcaccagtcattcaacacgttgagcgggtgtttacctcgctctatcaggatgcggttagt
tctggactctctagtagccagagcgaagtgctgttcgccggactaagcgcgcagcttgca
cgttggcaggacagattacgcggtattacgctgttgcaggaatgcccagacggggtgcgc
gccgagatcgtggttgcgggtgagcgtttgtctgctgcgttgatggagcaagtcatgctg
gcaaaaggcattacttcggcgcagctagacccacgtgaactatttttaggccgtggtcgt
ccgctagaatccgtggtcgatattgccgtcagcaaaccgcgattcaaaaatcttgccctc
gatgagaagcgggtttgggtgatgcccggctttaccgccgccgatgaagacggcaaggtt
gtgaccttaggccgtaacggttctgattactctgctgccgtgctggccgcttgtttagat
gcttcaagctgcgagatttggaccgacgttgacggcgtatacaataccgatcctcgggtt
gttaccgatgctaagttgttgtcacagctcagttatcaagaggcgatggagctgtcttac
tttggggctaaggtgctgcatcctaaaactattgcgcctatcgcccagttccacatcccc
tgttatatcaaaaacagctttaatcccgatgcgcccggcactctggtatcgaatcaggcc
gatgaaagcggtttgcaggtgaaggccatttctaatctggataatcaaaccatgtttgat
gtatcaggccctggtatgaaaggcatggtcggcatggcgagtcgcacactggctgcaatt
tcccgtagtggcgtttctgtgtcactcatcacccagagttcttgcgaatacagcatcagt
ttttgtgtggcgaccagtgagtccgccaaggtgaaatcggcgcttgagcaagagtttgag
ttagaaattaaaagtgacttgctagaaccgattgcaatgcgccatgacttagccattgtc
tcgttaattggcgatggcatgcgtacccataaaggtgtggcggcgcggtttttccaagca
ttagcacaggcgagtgtgaatattatcgcgattgcccaaggctcttctgaacgttctatt
tcaacagtgatcgaacagcgaaagaccaagcatgcggttgccgcctgtcatcagggcttt
ttcgatgtgcagcagtatctagatgtgtttttagtggggtgcggtaacgttggtgcaggc
ttactggagcagatcaaacaacaggcgagtgtgctaaaagagcagcacattagcatccgt
gtctgcggtatcgtcaattcaagcaagatgttactcgatagtgcaggtatcgatttaaac
aattggcaaaacctgcttgccgatagccagcagccaagcgatatacctgcgctattggcg
tgggtgaaagagcaacagttattaaaccctgtgctggtggattgtacttcaagcgatcaa
gtatcgaaccagtatttagaggtgatgaacgcgggcatgcacgtggtgacgccgaataaa
aaggctaacactcgcgattacgcctattaccaagctttgcgtcaaacagcattaaagcaa
cgtcggcagttcctttacgaaaccaacgtgggcgcaggattacccgttatcgataacttg
aaaaaactgttattcgccggtgataaattgcacaagtttaatggcattttgtcaggctcc
ttatcctttatcttcggtaaacttgatgaggggatgtcactttctgaggcgactaaactg
gcgcgggaaaaatgctttactgaacctgatcctcgcgatgatttaagtggcatggatgtg
gcgcgtaaggtactgattttggcccgtgaagtgggtttgaaacttgaactaaatgatatt
gttgtcgactcagtcttacccgcaggttttgatgattcaggcgatgtggaaagttttatg
gcacgtttacccgaggctgatgcggcgattgcggcgcgagtggcggaggcgaaagcgcag
ggtaaagtgctgcgttatgtcgggcagattgaagaaggcgcgtgttatgtgcgtatcacc
gaagtcgatgccactgatccactttatagcgtaaaaggcggtgaaaacgccttggcattc
tacagccgttattatcagcctattccctttgtgttgcgtggctatggtgcgggcacagaa
gtgactgcggcaggtgcctttgccgatgtattaagaaccttaaattggactcgtgaggtg
agtgtatga
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