Shigella sp. PIB: LXH19_06025
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Entry
LXH19_06025 CDS
T10707
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
shig Shigella sp. PIB
Pathway
shig00230
Purine metabolism
shig01100
Metabolic pathways
shig01110
Biosynthesis of secondary metabolites
Module
shig_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
shig00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
LXH19_06025 (purL)
Enzymes [BR:
shig01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
LXH19_06025 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
USJ83254
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Position
1251586..1255473
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTREVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAVQALVAQCKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVS
GDRFVITSNGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAVLESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacactatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccatgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctg
caacaggtaaaccgtcttgagcgcggcgtggcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagc
gttgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatttgcaggatgctttcacaaagcttggtcgtaac
ccgaacgacatcgaactgtatatgtttgcccaggcgaactccgagcactgccgccacaaa
atttttaacgccgactgggttatcgatggtgaacagcagccgaaatcgctgtttaagatg
atcaaaaacaccttcgaaaccacgccggatcacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaacctgcgcatatcctgatgaaagttgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccgggcgcggcgcgaagccgaaagctggtctggtcggtttctccgtgtccaacctg
cgaattcctggcttcgaacaaccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgttggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgtccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaatatt
cgcgccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcgtctggtcag
tctgatgccgacctcgacttcgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcggg
cgcggcggtaaattcgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcgccatacgcggtgattggtgaagcg
accgaagaactgcatctttctttgcacgatcgtcattttgataatcagccgatcgatctg
ccgctggacgtactgcttggtaaaacgccgaagatgacccgcgaagtacaaacgctgaaa
gcgaagggtgatgcgctggttcgtgaagggattaccattgctgacgcggtgaaacgcgtg
ctgcacctgccgaccgtggcggagaaaactttcctggtgaccattggtgaccgcagcgta
accggcatggtagcgcgcgatcagatggtgggtccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgacagctactacggcgaagcgatggcgattggcgagcgt
gcgccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgtta
accaatattgccgcaacacagattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagaactttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctg
gtgatttctgcatttgcccgtgtggaagatgtgcgtcacaccatcacgccgcagctttct
accgaagataacgcattactgctgattgatctgggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgacgtc
gcgcaactgaaaggtttctatgacgcggttcaggcgctggtagcacagtgtaagctgctc
gcgtaccacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgct
ggtcattgcggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggtgcggtgattcaggttcgtgccgctgaccgtgaagcagttgaa
gcggtactggcacagcatgggcttgcggattgcgtccattatgtagggcaggcggtttcc
ggtgaccgttttgtgattacctccaacgggcagactgtattcagcgaaagccgcactacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgccgatcaggagcatcaggcgaaatcaaacgacgccgatccgggcctgaatgtaaaa
ctgtcgttcgatatcaacgaagatgtggcagcaccgtatattgccactggcgcacgtccg
aaagttgctgtgctgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcgggctttgatgctatcgacgtgcatatgagcgacctgctggctggacgcacg
ggcctggaagatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctg
ggtgccggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaat
acctccgatcgctttgaagcgcgtttcagcctggttgaagtaacccaaagcccgtctctg
ctgttgcaggggatggtgggctcgcaaatgccgattgctgtctctcatggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggtactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccagctaacccgaacggttct
ccgaatggtattacggcagtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcgcgtaagcagttggggtaa
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