Streptomyces hygroscopicus subsp. jinggangensis TL01: SHJGH_3333
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Entry
SHJGH_3333 CDS
T02531
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sho
Streptomyces hygroscopicus subsp. jinggangensis TL01
Pathway
sho00300
Lysine biosynthesis
sho00550
Peptidoglycan biosynthesis
sho01100
Metabolic pathways
sho01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sho00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SHJGH_3333
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SHJGH_3333
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SHJGH_3333
Enzymes [BR:
sho01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SHJGH_3333
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
Motif
Other DBs
NCBI-ProteinID:
AGF62998
LinkDB
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Position
complement(3840791..3842206)
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AA seq
471 aa
AA seq
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MIALSLAEIAAVVGGQTHDIPDPSVQVTGPVVRDSREVVPGSLFAAFVGERVDGHDYARA
VTEAGAVAVLASRPVGVPAIVVEDVQTALGALARHVVHRLGATLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGSAHIGEFGGREQIAQAKGELVEALPPAEEGGVAILNADDPLVRAMASRTKAKV
VLFGESAEADVRAENVRLTDSGQPSFRLHTPSGASDLTMRLYGEHHVSNALAAAAVAHEL
GMSAEEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGKGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGIEASWLQLGAYNEGSWGEESV
HVSDAQAAIDLLRSELRPGDVVLVKASRSVGLESVAQALVETGAEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagctgtcgtcggcgggcagacgcacgacata
ccggatccgtccgtgcaggtcacgggaccggtcgtccgggactcccgcgaggtggtgccc
ggcagcctgttcgccgccttcgtcggcgagcgcgtggacggccacgactacgcccgggcg
gtgaccgaggccggcgcggtcgccgtgctggcctcccgcccggtcggcgttcccgcaatc
gtcgtcgaggacgtccagacggccctcggcgccctcgcccggcacgtcgtacaccggctc
ggcgcgaccctcgtcgccctgaccggctcggccggcaagaccagcaccaaggacctcatc
gcccaggtgctgcggcgcaaggcaccgacggtgttcacgcccggctcgctcaacaacgag
atcgggctgccgctgaccgccctgtccgccaccgaggagacacggttcctcgtgctggag
atgggcgcccggggcatcgggcacatccgctacctcaccggtctcaccccgccgaggatc
ggcctggtgctcaacgtcggcagcgcccacatcggcgagttcggcggacgtgagcagatc
gcccaggccaagggcgaactcgtggaggccctccccccggcggaggagggcggcgtggcg
atcctcaacgccgacgacccgctggtgcgggccatggcctcccgtaccaaggcgaaggtg
gtccttttcggagagtcggccgaagcggacgtacgggccgagaacgtacgactcacggac
agcggacagccctccttcaggcttcacacaccctccggtgcaagtgatctgacgatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcggaagagatcgccaccgcgctctcggaggcgggctccctctcccgctgg
cgcatggaggtcaccgagcgcccggacggcgtgaccatcgtcaacgacgcctacaacgcc
aaccccgagtccatgcgggccgccctcagggcgctcgcggccatgggcaaggggcgccgc
acgtgggcggtgctcggcaagatggccgagctgggggacgaggcgctcgccgagcacgac
gccgtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgccgtcggggggatt
gaggcctcctggctgcaattgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcgatcgacctgttgcgcagcgagttgcgcccgggggac
gtcgtgctcgtgaaggcgtcccgttcggtgggtctggagagcgtcgcccaggcgctcgtc
gagaccggtgccgagggtgaggttgccgcccgatga
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