Streptomyces hygroscopicus subsp. jinggangensis TL01: SHJGH_6309
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Entry
SHJGH_6309 CDS
T02531
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sho
Streptomyces hygroscopicus subsp. jinggangensis TL01
Pathway
sho00290
Valine, leucine and isoleucine biosynthesis
sho00620
Pyruvate metabolism
sho01100
Metabolic pathways
sho01110
Biosynthesis of secondary metabolites
sho01210
2-Oxocarboxylic acid metabolism
sho01230
Biosynthesis of amino acids
Module
sho_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sho00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SHJGH_6309
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SHJGH_6309
Enzymes [BR:
sho01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SHJGH_6309
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Gene cluster
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Herpes_UL56
Motif
Other DBs
NCBI-ProteinID:
AGF65972
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Position
complement(7149182..7150867)
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AA seq
561 aa
AA seq
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MTTTPVWNPQRPSPMPYHRYRPFQDRVSVPVTDRAWPAARIERAPLWVPVDLRDGNQALA
EPMDTPRKRRFFDLLVAVGFKEIEVGYPSASRTDFDFVRHLADGGVVPDDVTPVVFTPAR
ADLIDRTFDAIEGLPRAVVHLYIATSPVWREVVLGRSRAEVWRTVRAAAEHMARRAGDAP
GVRFQFSPETFNLTEPDFVLELCDGLTELWDASPDRPVTHNLPATVEIATPNVYADQIEY
AHRNLARRDSVILSVHPHNDRGTGVACAELAVLAGAQRVEGCLFGNGERTGNVDLVTLAL
NLYAQGVDPMVDLGDIDAVRETVEHCNRLPVHPRHPYAGELVHTAFSGTHQDAIGKGLAE
HARRARESGVPKAQAPWSVPYLPIDPADVGRSYEAVIRVNSQSGKGGVAYLLRTHHGIDL
PARMRADFARVVQEATDDSGREATPKELYELFRATYLTDGAAVRLHDWSVREEAPGVHRF
VCTLEAGDRVGDHEGTGAGPLTAFVDALAGAGVAVEVVDFTEDATAAFAECRVGGVTAWG
AGTGPSAAVHAVLSAVNRAVR
NT seq
1686 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccacccccgtctggaacccccagcggcccagcccgatgccgtaccaccgctac
cgccccttccaggaccgggtgagcgtgcccgtgaccgaccgcgcctggcccgccgcccgg
atcgagcgcgccccgctgtgggtgcccgtggatctgcgcgacggcaaccaggcgctggcc
gagcccatggacacgccccgcaagcgccgcttcttcgacctgctggtggcggtgggcttc
aaggagatcgaggtcggctatccgtccgcgagccgtaccgacttcgacttcgtccggcac
ctggcggacggcggggtggtgccggacgacgtgacgcccgtcgtcttcacgcccgcccgc
gccgacctgatcgaccggaccttcgacgcgatcgaggggctgccgcgggccgtggtccac
ctgtacatcgccacctcgccggtctggcgggaggtggtgctcggtcgcagccgggccgag
gtgtggcggaccgtgcgcgcggcggcggagcacatggcccggcgggccggggacgcgccc
ggcgtccgcttccagttctcgccggagacgttcaacctcaccgagccggacttcgtcctg
gaactgtgcgacgggctcacggagttgtgggacgcgagccccgaccgcccggtcacccac
aacctcccggcgaccgtggagatcgccacgccgaacgtctacgccgaccagatcgagtac
gcgcaccgcaacctcgcccgccgggactccgtgatcctctcggtgcatccgcacaacgac
cgcggcacgggggtcgcctgcgcggaactcgccgtgctggccggcgcccagagggtggag
ggctgcctgttcggcaacggcgagcgcaccggtaacgtcgacctggtgaccctcgccctc
aacctctacgcccagggggtcgaccccatggtcgacctcggcgacatcgacgccgtacgg
gagacggtggagcactgcaaccggctgccggtgcacccgcgccacccctatgccggggaa
ctggtccacacggcgttctccggcacccaccaggacgcgatcggcaagggcctggccgag
cacgcgcgccgcgcccgggagtcgggggtgcctaaggcccaggcgccgtggtcggtgccg
tatctgccgatcgacccggcggacgtggggcggtcgtacgaggcggtgatccgcgtcaac
tcccagtcgggcaagggcggggtggcgtatctgctgcgcacgcaccacggcatcgacctg
ccggcgcggatgcgggccgacttcgcgcgggtcgtgcaggaggcgacggacgacagcggg
cgggaggcgacgccgaaggagctgtacgagctgttccgggcgacctacctgacggacggg
gcggcggtacggctgcacgactggtccgtgcgggaagaggcacccggcgtgcaccgcttc
gtctgcaccctggaggccggcgaccgcgtcggcgaccacgagggcacgggcgccggtccg
ctgaccgccttcgtcgacgcgctggccggtgcgggcgtcgcggtcgaggtcgtggacttc
accgaggacgcgacggcggccttcgccgagtgccgggtcggcggcgtcacggcctggggc
gcgggaacggggccgtcggccgccgtgcacgcggtgctgtccgcggtgaaccgggcggtg
cgatga
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