KEGG   Sturnira hondurensis: 118986375
Entry
118986375         CDS       T07222                                 
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
shon  Sturnira hondurensis
Pathway
shon00562  Inositol phosphate metabolism
shon01100  Metabolic pathways
shon01521  EGFR tyrosine kinase inhibitor resistance
shon01522  Endocrine resistance
shon01524  Platinum drug resistance
shon04012  ErbB signaling pathway
shon04014  Ras signaling pathway
shon04015  Rap1 signaling pathway
shon04024  cAMP signaling pathway
shon04062  Chemokine signaling pathway
shon04066  HIF-1 signaling pathway
shon04068  FoxO signaling pathway
shon04070  Phosphatidylinositol signaling system
shon04071  Sphingolipid signaling pathway
shon04072  Phospholipase D signaling pathway
shon04081  Hormone signaling
shon04140  Autophagy - animal
shon04145  Phagocytosis
shon04150  mTOR signaling pathway
shon04151  PI3K-Akt signaling pathway
shon04152  AMPK signaling pathway
shon04210  Apoptosis
shon04211  Longevity regulating pathway
shon04213  Longevity regulating pathway - multiple species
shon04218  Cellular senescence
shon04360  Axon guidance
shon04370  VEGF signaling pathway
shon04380  Osteoclast differentiation
shon04510  Focal adhesion
shon04517  IgSF CAM signaling
shon04518  Integrin signaling
shon04550  Signaling pathways regulating pluripotency of stem cells
shon04611  Platelet activation
shon04613  Neutrophil extracellular trap formation
shon04620  Toll-like receptor signaling pathway
shon04625  C-type lectin receptor signaling pathway
shon04630  JAK-STAT signaling pathway
shon04650  Natural killer cell mediated cytotoxicity
shon04660  T cell receptor signaling pathway
shon04662  B cell receptor signaling pathway
shon04664  Fc epsilon RI signaling pathway
shon04666  Fc gamma R-mediated phagosome formation
shon04668  TNF signaling pathway
shon04670  Leukocyte transendothelial migration
shon04722  Neurotrophin signaling pathway
shon04725  Cholinergic synapse
shon04750  Inflammatory mediator regulation of TRP channels
shon04810  Regulation of actin cytoskeleton
shon04910  Insulin signaling pathway
shon04914  Progesterone-mediated oocyte maturation
shon04915  Estrogen signaling pathway
shon04917  Prolactin signaling pathway
shon04919  Thyroid hormone signaling pathway
shon04923  Regulation of lipolysis in adipocytes
shon04926  Relaxin signaling pathway
shon04929  GnRH secretion
shon04930  Type II diabetes mellitus
shon04931  Insulin resistance
shon04932  Non-alcoholic fatty liver disease
shon04933  AGE-RAGE signaling pathway in diabetic complications
shon04935  Growth hormone synthesis, secretion and action
shon04960  Aldosterone-regulated sodium reabsorption
shon04973  Carbohydrate digestion and absorption
shon05010  Alzheimer disease
shon05017  Spinocerebellar ataxia
shon05020  Prion disease
shon05100  Bacterial invasion of epithelial cells
shon05132  Salmonella infection
shon05135  Yersinia infection
shon05142  Chagas disease
shon05146  Amoebiasis
shon05160  Hepatitis C
shon05161  Hepatitis B
shon05162  Measles
shon05163  Human cytomegalovirus infection
shon05164  Influenza A
shon05165  Human papillomavirus infection
shon05166  Human T-cell leukemia virus 1 infection
shon05167  Kaposi sarcoma-associated herpesvirus infection
shon05168  Herpes simplex virus 1 infection
shon05169  Epstein-Barr virus infection
shon05170  Human immunodeficiency virus 1 infection
shon05171  Coronavirus disease
shon05200  Pathways in cancer
shon05203  Viral carcinogenesis
shon05205  Proteoglycans in cancer
shon05206  MicroRNAs in cancer
shon05207  Chemical carcinogenesis - receptor activation
shon05208  Chemical carcinogenesis - reactive oxygen species
shon05210  Colorectal cancer
shon05211  Renal cell carcinoma
shon05212  Pancreatic cancer
shon05213  Endometrial cancer
shon05214  Glioma
shon05215  Prostate cancer
shon05218  Melanoma
shon05220  Chronic myeloid leukemia
shon05221  Acute myeloid leukemia
shon05222  Small cell lung cancer
shon05223  Non-small cell lung cancer
shon05224  Breast cancer
shon05225  Hepatocellular carcinoma
shon05226  Gastric cancer
shon05230  Central carbon metabolism in cancer
shon05231  Choline metabolism in cancer
shon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
shon05415  Diabetic cardiomyopathy
shon05417  Lipid and atherosclerosis
shon05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:shon00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    118986375 (PIK3CD)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    118986375 (PIK3CD)
   04014 Ras signaling pathway
    118986375 (PIK3CD)
   04015 Rap1 signaling pathway
    118986375 (PIK3CD)
   04370 VEGF signaling pathway
    118986375 (PIK3CD)
   04630 JAK-STAT signaling pathway
    118986375 (PIK3CD)
   04668 TNF signaling pathway
    118986375 (PIK3CD)
   04066 HIF-1 signaling pathway
    118986375 (PIK3CD)
   04068 FoxO signaling pathway
    118986375 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    118986375 (PIK3CD)
   04072 Phospholipase D signaling pathway
    118986375 (PIK3CD)
   04071 Sphingolipid signaling pathway
    118986375 (PIK3CD)
   04024 cAMP signaling pathway
    118986375 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    118986375 (PIK3CD)
   04152 AMPK signaling pathway
    118986375 (PIK3CD)
   04150 mTOR signaling pathway
    118986375 (PIK3CD)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    118986375 (PIK3CD)
   04517 IgSF CAM signaling
    118986375 (PIK3CD)
   04518 Integrin signaling
    118986375 (PIK3CD)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    118986375 (PIK3CD)
   04140 Autophagy - animal
    118986375 (PIK3CD)
  09143 Cell growth and death
   04210 Apoptosis
    118986375 (PIK3CD)
   04218 Cellular senescence
    118986375 (PIK3CD)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118986375 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    118986375 (PIK3CD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118986375 (PIK3CD)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118986375 (PIK3CD)
   04613 Neutrophil extracellular trap formation
    118986375 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    118986375 (PIK3CD)
   04625 C-type lectin receptor signaling pathway
    118986375 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    118986375 (PIK3CD)
   04660 T cell receptor signaling pathway
    118986375 (PIK3CD)
   04662 B cell receptor signaling pathway
    118986375 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    118986375 (PIK3CD)
   04666 Fc gamma R-mediated phagosome formation
    118986375 (PIK3CD)
   04670 Leukocyte transendothelial migration
    118986375 (PIK3CD)
   04062 Chemokine signaling pathway
    118986375 (PIK3CD)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118986375 (PIK3CD)
   04923 Regulation of lipolysis in adipocytes
    118986375 (PIK3CD)
   04929 GnRH secretion
    118986375 (PIK3CD)
   04915 Estrogen signaling pathway
    118986375 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    118986375 (PIK3CD)
   04917 Prolactin signaling pathway
    118986375 (PIK3CD)
   04926 Relaxin signaling pathway
    118986375 (PIK3CD)
   04935 Growth hormone synthesis, secretion and action
    118986375 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    118986375 (PIK3CD)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    118986375 (PIK3CD)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    118986375 (PIK3CD)
  09156 Nervous system
   04725 Cholinergic synapse
    118986375 (PIK3CD)
   04722 Neurotrophin signaling pathway
    118986375 (PIK3CD)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118986375 (PIK3CD)
  09158 Development and regeneration
   04360 Axon guidance
    118986375 (PIK3CD)
   04380 Osteoclast differentiation
    118986375 (PIK3CD)
  09149 Aging
   04211 Longevity regulating pathway
    118986375 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    118986375 (PIK3CD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118986375 (PIK3CD)
   05206 MicroRNAs in cancer
    118986375 (PIK3CD)
   05205 Proteoglycans in cancer
    118986375 (PIK3CD)
   05207 Chemical carcinogenesis - receptor activation
    118986375 (PIK3CD)
   05208 Chemical carcinogenesis - reactive oxygen species
    118986375 (PIK3CD)
   05203 Viral carcinogenesis
    118986375 (PIK3CD)
   05230 Central carbon metabolism in cancer
    118986375 (PIK3CD)
   05231 Choline metabolism in cancer
    118986375 (PIK3CD)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118986375 (PIK3CD)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118986375 (PIK3CD)
   05212 Pancreatic cancer
    118986375 (PIK3CD)
   05225 Hepatocellular carcinoma
    118986375 (PIK3CD)
   05226 Gastric cancer
    118986375 (PIK3CD)
   05214 Glioma
    118986375 (PIK3CD)
   05221 Acute myeloid leukemia
    118986375 (PIK3CD)
   05220 Chronic myeloid leukemia
    118986375 (PIK3CD)
   05218 Melanoma
    118986375 (PIK3CD)
   05211 Renal cell carcinoma
    118986375 (PIK3CD)
   05215 Prostate cancer
    118986375 (PIK3CD)
   05213 Endometrial cancer
    118986375 (PIK3CD)
   05224 Breast cancer
    118986375 (PIK3CD)
   05222 Small cell lung cancer
    118986375 (PIK3CD)
   05223 Non-small cell lung cancer
    118986375 (PIK3CD)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118986375 (PIK3CD)
   05170 Human immunodeficiency virus 1 infection
    118986375 (PIK3CD)
   05161 Hepatitis B
    118986375 (PIK3CD)
   05160 Hepatitis C
    118986375 (PIK3CD)
   05171 Coronavirus disease
    118986375 (PIK3CD)
   05164 Influenza A
    118986375 (PIK3CD)
   05162 Measles
    118986375 (PIK3CD)
   05168 Herpes simplex virus 1 infection
    118986375 (PIK3CD)
   05163 Human cytomegalovirus infection
    118986375 (PIK3CD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118986375 (PIK3CD)
   05169 Epstein-Barr virus infection
    118986375 (PIK3CD)
   05165 Human papillomavirus infection
    118986375 (PIK3CD)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118986375 (PIK3CD)
   05135 Yersinia infection
    118986375 (PIK3CD)
   05100 Bacterial invasion of epithelial cells
    118986375 (PIK3CD)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118986375 (PIK3CD)
   05142 Chagas disease
    118986375 (PIK3CD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118986375 (PIK3CD)
   05017 Spinocerebellar ataxia
    118986375 (PIK3CD)
   05020 Prion disease
    118986375 (PIK3CD)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118986375 (PIK3CD)
   05418 Fluid shear stress and atherosclerosis
    118986375 (PIK3CD)
   05415 Diabetic cardiomyopathy
    118986375 (PIK3CD)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    118986375 (PIK3CD)
   04932 Non-alcoholic fatty liver disease
    118986375 (PIK3CD)
   04931 Insulin resistance
    118986375 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118986375 (PIK3CD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118986375 (PIK3CD)
   01524 Platinum drug resistance
    118986375 (PIK3CD)
   01522 Endocrine resistance
    118986375 (PIK3CD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:shon04131]
    118986375 (PIK3CD)
Enzymes [BR:shon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     118986375 (PIK3CD)
Membrane trafficking [BR:shon04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    118986375 (PIK3CD)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2 CCDC17_C
Other DBs
NCBI-GeneID: 118986375
NCBI-ProteinID: XP_036901192
LinkDB
Position
Unknown
AA seq 1044 aa
MPPGVDCPMEFWASEENQNVAVDFLLPTGVYLNFSVSRNANLSTIKKALWHRAQYEPLFH
MLSGPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRVKMRQFCEEAAARRQQLGWEAWLQYCFPLQLEPSARTWGA
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLERPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLTLFDYKDQLKTGEYCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALVICLPEVAP
YPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDSSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMRVLMKQGEALSKLKALNDFVKVSSQKTPKPQAKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYCNEEAGSNGSVGIMFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTSNSEKFERFRGYC
ERAYTILRRHGPLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt   +upstreamnt  +downstreamnt
atgcccccgggggtggactgccccatggaattctgggccagcgaggagaatcagaacgtg
gcagttgactttctgctccccacgggggtctatctgaacttctctgtgtcccgaaatgcc
aacctcagcaccatcaagaaggcgctgtggcaccgcgcgcagtatgagccgctcttccac
atgctcagtggccccgaggcctacgtgttcacctgcgtcaaccagaccgcggagcagcag
gagctggaggacgagcagcggcggctctgtgacatccagcccttcctgccggtcctgcgc
ctggtggcccgagagggcgacagggtgaagaagctcatcaactcacagatcagcctcctc
attggcaaaggcctgcacgagttcgattctttgtgcgacccggaagtgaatgactttcga
gtcaagatgcgacagttctgcgaggaggccgccgcccgccggcagcagctgggctgggag
gcctggctgcagtactgcttccccctgcagctggagccctcggctcggacctggggggca
ggcaccctgcgggtccccaaccgggccctcctggtcaacgtcaagttcgagggcagtgag
gaaagcttcaccttccaggtgtctaccaaggacgtgcccctggccctgatggcctgtgcc
ctccggaagaaggccacggtgtttcggcagccgctggtggagcagcccgaggactacacc
ctgcaggtgaacgggaagcacgagtacctgtacggcagctaccccctctgccagttccag
tacatctgcagctgcctgcacagcgggctgacccctcacctgaccatggtgcactcctcc
tccatcctcgccatgcgggacgagcagagcaaccccgccccccaagtccagaagccacgt
accaaaccaccccccatccccatgaaaaagccctcctctgtgtccctgtggtccctggag
cggcccttctgcatcgagctgattcagggcagcaaagtgaacgccgacgagaggatgaag
ctggtggtgcaggccgggctctttcacggcaacgagacgctgtgcaagacggtgtccagc
tcggaggtgagcgtgtgctcggagcccgtgtggaagcagcgcctggagtttgacatcaac
atctgtgacctgccgcgcatggcccgcctctgcttcgcactgtacgccgtgatcgagaag
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccatcgcctgg
gccaatctcaccctgtttgactacaaggaccagctcaagaccggtgaatactgcctctac
atgtggccctccgtcccagacgagaaaggggagctgctgaaccccacagggaccgtatgc
agcaaccccaacaccgagagcgccgccgcccttgtcatctgtctcccggaggtggctccc
taccctgtgtactaccctgccctggacaagatcctggagctggggcggcacggggaacac
gggcgcttcaccgaggaggagcagctgcagcttcgggagatcctggagcggcgtgggtct
ggggaactgtacgagcatgagaaggacctggtgtggaagatgcgccacgaggtccaggag
cacttccccgaggcgctggcccggctgctgctggtcaccaagtggaacaagcacgaggac
gtggcccagatgctctacctgctgtgctcctggccggagctgcctgtgctgagcgccctg
gagctgctggactccagcttccccgaccggcatgtgggctcctttgctatcaagtccctg
cggaaactgacggatgatgagcttttccagtacctgctgcagctggtgcaggtgctcaag
tacgagtcctacctcgactgcgagctgaccaagttcctgctggaccgggccctggccaac
cgcaagatcggccacttcctcttctggcacctccgctccgagatgcatgtgccgtcggtg
gccctgcgcttcggcctcatcatggaggcctactgcaggggcagcacccaccacatgagg
gtgctgatgaagcagggggaagcgctgagcaagctgaaggccctgaacgactttgtcaaa
gtgagctcccagaagacccccaagccccaggccaaggagctgatgcacctgtgcatgcgt
caggagacctacctggaggccctctcccacctgcagtccccactggaccccagcatcctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagccgctgtgg
gtcatgtactgcaatgaggaggcaggcagcaacggcagtgtgggcatcatgtttaagaac
ggggacgacctccgccaggacatgctgaccctgcagatgatccagctcatggacgtgctc
tggaagcaggaggggttggacctgaggatgaccccttacggctgcctctccaccggggac
cgcacgggcctcatcgaggtggtgctgcactccgacaccatcgccaacatccagctgaac
aagagcaacatggcagccacagccgctttcaacaaggacgccctgctcaactggctcaag
tccaagaaccccggggaggccctggacagagccattgaggagttcaccctgtcctgcgcc
ggctattgtgtggccacgtacgtgctgggcatcggcgatcggcacagcgacaacatcatg
atccgcgagaacgggcagctgttccacattgattttggccattttctggggaacttcaag
accaagtttggaatcaaccgtgagcgagtcccgttcatcctcacctatgactttgtccac
gtgattcagcagggaaagactagtaatagtgagaaatttgaaaggttccgcggctactgc
gagagagcctacaccatcctgagacgccacgggccgctcttcctgcacctcttcgccctg
atgcgcgcggcgggcctgcccgagctcagctgctccaaagacatccagtacctcaaggac
tcgctggcgctggggaagacggaggaggaggctctgaagcactttcgcgtgaagttcaac
gaagccctccgcgagagctggaagaccaaagtgaattggctggcccacaacgtgtccaaa
gacaacaggcagtag

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