KEGG   Sturnira hondurensis: 118990300
Entry
118990300         CDS       T07222                                 
Symbol
RAF1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase
  KO
K04366  RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
Organism
shon  Sturnira hondurensis
Pathway
shon01521  EGFR tyrosine kinase inhibitor resistance
shon01522  Endocrine resistance
shon04010  MAPK signaling pathway
shon04012  ErbB signaling pathway
shon04014  Ras signaling pathway
shon04015  Rap1 signaling pathway
shon04022  cGMP-PKG signaling pathway
shon04024  cAMP signaling pathway
shon04062  Chemokine signaling pathway
shon04068  FoxO signaling pathway
shon04071  Sphingolipid signaling pathway
shon04072  Phospholipase D signaling pathway
shon04140  Autophagy - animal
shon04150  mTOR signaling pathway
shon04151  PI3K-Akt signaling pathway
shon04210  Apoptosis
shon04218  Cellular senescence
shon04270  Vascular smooth muscle contraction
shon04360  Axon guidance
shon04370  VEGF signaling pathway
shon04371  Apelin signaling pathway
shon04510  Focal adhesion
shon04540  Gap junction
shon04550  Signaling pathways regulating pluripotency of stem cells
shon04613  Neutrophil extracellular trap formation
shon04625  C-type lectin receptor signaling pathway
shon04630  JAK-STAT signaling pathway
shon04650  Natural killer cell mediated cytotoxicity
shon04660  T cell receptor signaling pathway
shon04662  B cell receptor signaling pathway
shon04664  Fc epsilon RI signaling pathway
shon04666  Fc gamma R-mediated phagocytosis
shon04720  Long-term potentiation
shon04722  Neurotrophin signaling pathway
shon04726  Serotonergic synapse
shon04730  Long-term depression
shon04810  Regulation of actin cytoskeleton
shon04910  Insulin signaling pathway
shon04912  GnRH signaling pathway
shon04914  Progesterone-mediated oocyte maturation
shon04915  Estrogen signaling pathway
shon04916  Melanogenesis
shon04917  Prolactin signaling pathway
shon04919  Thyroid hormone signaling pathway
shon04921  Oxytocin signaling pathway
shon04926  Relaxin signaling pathway
shon04928  Parathyroid hormone synthesis, secretion and action
shon04929  GnRH secretion
shon04935  Growth hormone synthesis, secretion and action
shon05010  Alzheimer disease
shon05022  Pathways of neurodegeneration - multiple diseases
shon05034  Alcoholism
shon05132  Salmonella infection
shon05152  Tuberculosis
shon05160  Hepatitis C
shon05161  Hepatitis B
shon05163  Human cytomegalovirus infection
shon05164  Influenza A
shon05165  Human papillomavirus infection
shon05167  Kaposi sarcoma-associated herpesvirus infection
shon05170  Human immunodeficiency virus 1 infection
shon05200  Pathways in cancer
shon05205  Proteoglycans in cancer
shon05206  MicroRNAs in cancer
shon05207  Chemical carcinogenesis - receptor activation
shon05208  Chemical carcinogenesis - reactive oxygen species
shon05210  Colorectal cancer
shon05211  Renal cell carcinoma
shon05212  Pancreatic cancer
shon05213  Endometrial cancer
shon05214  Glioma
shon05215  Prostate cancer
shon05218  Melanoma
shon05219  Bladder cancer
shon05220  Chronic myeloid leukemia
shon05221  Acute myeloid leukemia
shon05223  Non-small cell lung cancer
shon05224  Breast cancer
shon05225  Hepatocellular carcinoma
shon05226  Gastric cancer
shon05230  Central carbon metabolism in cancer
shon05231  Choline metabolism in cancer
shon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:shon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118990300 (RAF1)
   04012 ErbB signaling pathway
    118990300 (RAF1)
   04014 Ras signaling pathway
    118990300 (RAF1)
   04015 Rap1 signaling pathway
    118990300 (RAF1)
   04370 VEGF signaling pathway
    118990300 (RAF1)
   04371 Apelin signaling pathway
    118990300 (RAF1)
   04630 JAK-STAT signaling pathway
    118990300 (RAF1)
   04068 FoxO signaling pathway
    118990300 (RAF1)
   04072 Phospholipase D signaling pathway
    118990300 (RAF1)
   04071 Sphingolipid signaling pathway
    118990300 (RAF1)
   04024 cAMP signaling pathway
    118990300 (RAF1)
   04022 cGMP-PKG signaling pathway
    118990300 (RAF1)
   04151 PI3K-Akt signaling pathway
    118990300 (RAF1)
   04150 mTOR signaling pathway
    118990300 (RAF1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118990300 (RAF1)
  09143 Cell growth and death
   04210 Apoptosis
    118990300 (RAF1)
   04218 Cellular senescence
    118990300 (RAF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118990300 (RAF1)
   04540 Gap junction
    118990300 (RAF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    118990300 (RAF1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118990300 (RAF1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    118990300 (RAF1)
   04625 C-type lectin receptor signaling pathway
    118990300 (RAF1)
   04650 Natural killer cell mediated cytotoxicity
    118990300 (RAF1)
   04660 T cell receptor signaling pathway
    118990300 (RAF1)
   04662 B cell receptor signaling pathway
    118990300 (RAF1)
   04664 Fc epsilon RI signaling pathway
    118990300 (RAF1)
   04666 Fc gamma R-mediated phagocytosis
    118990300 (RAF1)
   04062 Chemokine signaling pathway
    118990300 (RAF1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118990300 (RAF1)
   04929 GnRH secretion
    118990300 (RAF1)
   04912 GnRH signaling pathway
    118990300 (RAF1)
   04915 Estrogen signaling pathway
    118990300 (RAF1)
   04914 Progesterone-mediated oocyte maturation
    118990300 (RAF1)
   04917 Prolactin signaling pathway
    118990300 (RAF1)
   04921 Oxytocin signaling pathway
    118990300 (RAF1)
   04926 Relaxin signaling pathway
    118990300 (RAF1)
   04935 Growth hormone synthesis, secretion and action
    118990300 (RAF1)
   04919 Thyroid hormone signaling pathway
    118990300 (RAF1)
   04928 Parathyroid hormone synthesis, secretion and action
    118990300 (RAF1)
   04916 Melanogenesis
    118990300 (RAF1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    118990300 (RAF1)
  09156 Nervous system
   04726 Serotonergic synapse
    118990300 (RAF1)
   04720 Long-term potentiation
    118990300 (RAF1)
   04730 Long-term depression
    118990300 (RAF1)
   04722 Neurotrophin signaling pathway
    118990300 (RAF1)
  09158 Development and regeneration
   04360 Axon guidance
    118990300 (RAF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118990300 (RAF1)
   05206 MicroRNAs in cancer
    118990300 (RAF1)
   05205 Proteoglycans in cancer
    118990300 (RAF1)
   05207 Chemical carcinogenesis - receptor activation
    118990300 (RAF1)
   05208 Chemical carcinogenesis - reactive oxygen species
    118990300 (RAF1)
   05230 Central carbon metabolism in cancer
    118990300 (RAF1)
   05231 Choline metabolism in cancer
    118990300 (RAF1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118990300 (RAF1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118990300 (RAF1)
   05212 Pancreatic cancer
    118990300 (RAF1)
   05225 Hepatocellular carcinoma
    118990300 (RAF1)
   05226 Gastric cancer
    118990300 (RAF1)
   05214 Glioma
    118990300 (RAF1)
   05221 Acute myeloid leukemia
    118990300 (RAF1)
   05220 Chronic myeloid leukemia
    118990300 (RAF1)
   05218 Melanoma
    118990300 (RAF1)
   05211 Renal cell carcinoma
    118990300 (RAF1)
   05219 Bladder cancer
    118990300 (RAF1)
   05215 Prostate cancer
    118990300 (RAF1)
   05213 Endometrial cancer
    118990300 (RAF1)
   05224 Breast cancer
    118990300 (RAF1)
   05223 Non-small cell lung cancer
    118990300 (RAF1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118990300 (RAF1)
   05161 Hepatitis B
    118990300 (RAF1)
   05160 Hepatitis C
    118990300 (RAF1)
   05164 Influenza A
    118990300 (RAF1)
   05163 Human cytomegalovirus infection
    118990300 (RAF1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118990300 (RAF1)
   05165 Human papillomavirus infection
    118990300 (RAF1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118990300 (RAF1)
   05152 Tuberculosis
    118990300 (RAF1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118990300 (RAF1)
   05022 Pathways of neurodegeneration - multiple diseases
    118990300 (RAF1)
  09165 Substance dependence
   05034 Alcoholism
    118990300 (RAF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118990300 (RAF1)
   01522 Endocrine resistance
    118990300 (RAF1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:shon01001]
    118990300 (RAF1)
Enzymes [BR:shon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     118990300 (RAF1)
Protein kinases [BR:shon01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   118990300 (RAF1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr RBD C1_1 Kinase-like ABC1 zf-RING-like Pkinase_fungal C1_2
Other DBs
NCBI-GeneID: 118990300
NCBI-ProteinID: XP_036906758
LinkDB
Position
Unknown
AA seq 648 aa
MEHIQGAWKTISNGFGFKDAVFDGPSCISPTIVQQFGYQRRASDDGKLTDSSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDMCQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNVRQLLLFPNSTLGDSGVPALPSLTMRRMRESVSRIPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNL
SPTGWSQPKTPVPAQRERAPGSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq 1947 nt   +upstreamnt  +downstreamnt
atggagcacatacagggggcctggaagacgatcagcaatggttttggattcaaagacgca
gtgtttgacggccccagctgcatttcccccacaatagttcagcagtttggctatcagcgc
cgagcgtcagatgatggcaaacttacagactcatctaagacaagcaatactattcgtgtt
ttcttgccaaacaagcaaagaacggtggtcaatgtacgaaatgggatgagcttgcatgac
tgccttatgaaagcactcaaggtgaggggcctgcaaccagagtgctgtgcagtgttcaga
cttctccatgaacacaaaggtaaaaaagcacgtttagattggaacactgatgctgcctcg
ttgattggagaagaacttcaagtagatttcctggatcatgttcccctcacaacacacaac
tttgctcggaagaccttcctgaagcttgccttctgtgacatgtgtcagaagttcctgcta
aatggatttcgatgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagta
cctactatgtgtgtggattggagtaatgtcagacaactcttattgtttccaaattctact
cttggcgatagtggggtcccagcactgccttctttgacaatgcgtcggatgcgagagtct
gtttcccggatacctgtcagttcccagcacagatactccacaccccacgccttcacgttc
aacacctccagcccctcctctgaaggttccctctcccagaggcagaggtcgacatccaca
cctaatgtccacatggtcagcactaccctgcctgtggacagcaggatgatcgaggatgca
attcgaagtcacagtgaatcagcctcaccttcagccttgtccagcagccccaacaatctg
agcccaacaggctggtcacagcccaaaacccctgtgccagcacagagagagcgggcacca
ggatctgggacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagttat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctccttt
ggaactgtttataagggcaagtggcatggagacgttgcagtaaagatcctaaaggttgtt
gaccccacacctgagcagttccaggccttcaggaacgaggtggctgtgctacgtaaaaca
cggcacgtgaacatcttgcttttcatggggtacatgacgaaggacaatctggcgatagtg
acccagtggtgcgaaggcagcagcctctacaaacacctgcatgtccaagagaccaagttc
caaatgttccagttgattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaacatatttctccatgaaggcctg
acagtgaaaattggagattttggtttggcaacagtgaagtcacgctggagtggttcacag
caggttgaacaacccactggctctatcctatggatggcccccgaggtgatccgaatgcag
gataataacccttttagcttccagtctgacgtctactcctatggcattgtgctgtatgag
cttatgacaggggagctaccttactcccacatcaacaaccgagatcagatcatcttcatg
gtgggccgagggtatgcctctccagaccttagtaagctatacaagaactgccccaaagca
atgaagcggcttgtcgcagactgtgtgaagaaggttaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctgctccaacactctctaccgaaaatcaaccggagcgct
tctgagccatccctgcatcgggcggcccacacggaggacatcaatgcctgcacactgacc
acgtcccctagactgcctgtcttctag

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