Sturnira hondurensis: 118995204
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Entry
118995204 CDS
T07222
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
shon
Sturnira hondurensis
Pathway
shon05012
Parkinson disease
shon05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
shon00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
118995204 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
118995204 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shon01001
]
118995204 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
shon04131
]
118995204 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
shon04147
]
118995204 (LRRK2)
Enzymes [BR:
shon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118995204 (LRRK2)
Protein kinases [BR:
shon01001
]
Serine/threonine kinases: TKL group
LRRK family
118995204 (LRRK2)
Membrane trafficking [BR:
shon04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
118995204 (LRRK2)
Exosome [BR:
shon04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
118995204 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
LRR_4
COR-B
Ras
COR-A
LRR_9
LRR_14
Arf
WD40_CDC20-Fz
WDR55
LRR_13
Beta-prop_EML_2
AAA_22
Beta-prop_ACSF4
WD40_2
TsaE
T2SSE
nSTAND3
Beta-prop_THOC3
AAA_7
Kdo
AAA_16
ABC_tran
PduV-EutP
TrwB_AAD_bind
Beta-prop_RIG_2nd
G-alpha
LRR_6
NACHT
nSTAND_NTPase5
MobB
NB-ARC
AAA_29
WD40_Prp19
Septin
SRPRB
FtsK_SpoIIIE
TniB
MMR_HSR1
cobW
ResIII
AAA_33
Motif
Other DBs
NCBI-GeneID:
118995204
NCBI-ProteinID:
XP_036914051
LinkDB
All DBs
Position
Unknown
AA seq
2528 aa
AA seq
DB search
MASGSCQGCEEEDQETLKKLIVRLNNLQEGKQIETLVQILEDMLVFTYADHASKLFQGKN
VHVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPNTLQSLMGPQDIGHDWEVLGVHQLII
KMLTVHLASRNLSTVGLKALDLLLTSDKITVLILDEETDIFLLIFDAMRTFSTNGEVQKL
GCKALQVLFERVSEEQLTEFVENKDYVVFLSAFKNFKDEEEVVLHVLHCLHSLAIPCNNV
EVLMSGNVRCYNIVVEAMKAFPVNEKIQEVSCCLLHRLTLDNFFNILVLNEVHEFVVKAV
QQYSENAALQIAALSCLALLTETIFLNQDLEEKNENPENDDDEDEDKLFWLEACYKALTG
HRKNKHVQEAACWALNNLLMYQNNLHKKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASA
NALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNTSLDV
MAAVAPNIVTVMKSHVTSSSVQLEALRAILHFIVPGMQGEFTGDTEYQHKINTVTELCFR
NDIHKLVLLSLKRFVRIPGIQKCGLKVISSVAHLPAALEALSLEGALDLVLQTLQMCPDD
QEIQCLGLSLIGCLITKKNLFLVTGRLLAKLLVSSLQRFKDVAELQIKGFQTVLTVLELS
VSFSKLLVHYSFDSVIFHQMSSSIVEQKDQQFLNLCCKCFAKLAMDDELKSLMLERACDQ
NNSIMAECLLLLGADANRAKEGASLICQVCEKGSHPKLVELLLSSRPRDQDVRKALTISI
GKGDGQTISLLLRRLALDPANNSICLGGFGIGKIEPSWLSPLFPDKTFNSRKETNIGCTL
ARMVLRYQMKSAAEEGAASGSNGHFSEEALNKCDEWTFIPECYLDSVFGQSDDLDSEGSE
GSCLEKKKSNSISVGEFYRDPALQRNSPILQRHPNSLGPIFSHEDLLKRKRKCLLSSDDS
LRSSKLPSHVRHSDSTSSLASERECITSLDLSANELRDIDALSQKCCISGHLEHLEKLEL
HQNALTSFPQRLCETLKCLTHLDLHSNKFTSFPSYLLKMNCITNLDVSRNDIGPSIVLDP
AVKCLTLKQFNLSYNQLTSVPENLGEVAEKLEQLMLEGNKISGMCSPLSLKELKILNLSK
NHISSLSEDFLEACPKVESFSARMNFLAAMPFLPSSMTSIKLSQNRFTCVPEAILNLPHL
RSLDMSSNDIQYLPSPAHWKSLNLRELLFSHNQISILNLSEKAHAWSRVEKLHLSHNKLK
EIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHVGCKAKDI
IRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGIQSPTVGIDVKDWPI
PLKGKRKKDLILNVWDFAGREEFYSTHPHFMTPRSLYLAVYDLSKGQAEVDAMKPWLFNI
KARASSSPVILVGTHLDVADERQRKACISKINKELLNKRGFPAIRDYHFVNATEESDALA
KLRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKQLLQLVK
GNQLQLDENELPHAIHFLNESGVLLHFQDPALQLSNLYFVEPKWLCKVMAQILTVKVEGY
SKHPKGIISRRDVEKFLSKKKRFPKNYMHQYFKLLEKFQIALPIGEEYLLVPSSLSDHRP
VIELPHCENSEIIIRLYEMPYFPMGFWSRLISRLLEISPYMLSGRERVLRPNRMYWRQGI
YLNWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEI
DICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPD
LILADLPRNIMLNSDELEFEQAPEFLLGDGSFGSVYRATYEGEEVAVKIFNKHTSLRLLR
QELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKATLTRTLQHRIALHV
ADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGF
RAPEVARGNVIYNQQADVYSFGLLLYDIFTSGGRIADGLKFPNEFDELAIQGKLPDPVKE
YGCAPWPLVEKLIERCLKENPQERPTSAQVFDILNSADLLCLMRHIAIHKNLTVECVVAT
SHSSRNASVWLGCGNADRGQLSFLDFTTERLTSEEVTDSRILCLALVHLPVEKESWIVSG
TQSGVLLVINTEDGNKRHTLERMTDSITCLYCNSSSRLSKQKNFLLVGTADGKLAIFEDK
TVKCKGAAPLKILTIGNVSTPLMCLSESVNSSERNIMWGGCGTKLFSLSDDFSIQKLIET
RTNQLFPSADFSDSNIIAVVVDTAVYIAKKNSPLVEVWDKKTDKLCELIDCVHFLKEDVG
KANKEAKHKMHYSGRVKTLCLQKNTALWIGTGGGSVLLLDLSTRRLIRRIHSYDSVRVMM
TAQLGSLKNAMLILGYSQKSTEGVQHQKELQSFLSIWDMNLPHEVQNLEKHIEVRKELAE
KMRRISVE
NT seq
7587 nt
NT seq
+upstream
nt +downstream
nt
atggccagcggcagctgtcaggggtgcgaagaggaggaccaggaaactttgaagaagttg
atagtcagactgaacaatctccaggaaggaaaacagatagagacgctggtccaaatcctg
gaggacatgctggtgttcacctacgctgaccacgcctccaagttatttcaaggcaaaaat
gtccacgtgcctctgttgatcgtcttggactcgtatatgagagttgcgagtgtgcagcag
gtgggttggtcacttctctgcaaattaattgaaatctgcccaaatacgttgcaaagcttg
atgggaccccaggatattggacacgattgggaagtccttggtgttcaccaactgattatt
aaaatgcttacagttcatcttgccagtagaaacctgtcaacggttggactgaaggcccta
gatctccttctaacttcagataaaatcactgttctaatattggacgaagaaactgatatt
ttcttattaatttttgatgccatgcgaacattttcaaccaacggcgaggtccagaaactt
gggtgcaaagctttacaagtgctgtttgagagagtttcggaggagcaactgactgaattt
gttgagaacaaagattatgtggtgtttctgagcgcatttaaaaacttcaaggacgaagag
gaagttgtgcttcatgtactacactgtttacattccctagcaattccttgcaataatgtt
gaagtgctcatgagtggcaatgtgaggtgttacaatattgtggtggaagccatgaaagca
ttccctgtcaatgaaaaaattcaagaagtaagttgctgcttgctccaccggcttacatta
gataattttttcaatatcctggtattaaatgaggtgcacgagtttgtggtgaaagccgtg
cagcagtattcggagaacgcggcattgcaaatagcagcgctcagctgtctagcgctcctc
actgagaccattttcttaaatcaagacttagaggagaagaatgaaaatccggagaatgac
gatgatgaggacgaagacaaattgttttggctagaagcctgttacaaagccttaacaggg
cacagaaagaacaagcatgtgcaggaagctgcgtgctgggccctaaacaatctccttatg
taccaaaacaatttgcacaagaagattggagatgaagatggccagttcccagctcacagg
gaagtgatgctgtccatgctgatgcattcgtcatcaaaagaagtttttcaggcatctgcg
aacgcattgtcgactctcttggaacaaaatgttaatttcagaaaaatcctgttgtcaaaa
ggaatatacctgaatgtgttggaattaatgcagaagcacatacattctcctgaagtggct
gagagtggctgcaagatgctaaatcatctttttgaaggaagtaacacttccctggatgtg
atggcagcagtggcccccaacatagtaacagttatgaaaagtcatgtgacgtcatcatca
gtacagctggaagcccttcgagctattttgcattttatagttccaggcatgcaaggagaa
ttcacaggagatactgaatatcagcacaagataaatacggttacagagctgtgtttcagg
aatgatattcacaaactggtcctcctatctttaaaaaggttcgtccgaattcctgggatt
cagaaatgtggacttaaagtaatttcttctgtagcacatttacctgctgcgttagaggcc
ttgtctctggaaggcgctcttgatttggtgcttcagacgctgcagatgtgtccggatgac
caagaaattcagtgtctgggtttaagtcttatagggtgcttgattacaaagaagaattta
ttcttggtaactggacgtctgctggcaaaacttctggtttccagcttacagcggtttaag
gacgtggctgaattacagattaaaggatttcagacagtcttgacagtactggaattgtcc
gtgtctttttccaagctgttggtgcattactcctttgactcagtgatattccatcagatg
tcttccagtattgtggaacaaaaagatcagcagttcctaaacctttgttgcaagtgcttt
gcaaagctagctatggatgatgagttgaaaagtttgatgctggagagagcgtgtgatcag
aacaacagcatcatggctgaatgcctgcttctgttgggagcggatgccaatcgagcaaag
gagggagcttctttaatctgccaggtatgtgaaaaagggagccaccccaagctggtggag
ctgttactgagtagcaggccccgtgatcaagatgtgcgtaaagcgctgacaatcagcatt
gggaaaggcgatggccaaaccatcagtctgctcttaaggaggcttgccctggacccggct
aacaacagcatctgcctcggaggatttgggataggaaaaattgaaccttcctggcttagt
cctttgttcccagacaagacatttaattcaagaaaagaaacaaatataggatgcacctta
gcaagaatggtcctcagataccagatgaaaagtgctgcagaagaaggagcagcctcaggc
agcaatgggcatttttccgaagaagcacttaataaatgtgatgagtggaccttcattcct
gagtgttacctggacagtgtatttggtcaaagtgatgatctagatagcgaaggaagtgaa
ggctcatgtcttgagaaaaagaagtcaaattcaattagcgtaggagaattttaccgagat
cctgccttgcagcgcaactcaccaattttgcaaaggcaccccaattcattggggcccatt
ttcagtcatgaagatttactgaagcggaaaagaaaatgtctgttgtcttcagatgattca
ctcaggtcatcgaaactcccatcccatgtgaggcattcggacagcacttcttctctggct
tctgagagagaatgtattacatcactagatctttcagcaaatgaactcagagacattgac
gccctgagccagaaatgctgtataagtgggcacttggagcatcttgaaaagctggagctt
caccagaatgcactcacgagcttcccacaacgactctgtgaaactctgaagtgtttgacc
catttggacttgcacagtaataaatttacatcatttccctcctacttgttgaaaatgaat
tgtattaccaaccttgatgtctctcgaaatgacatcggaccctcaatagttttggatcct
gcggtgaagtgtctgaccctgaaacagtttaacctgtcatataatcagctgacttctgtt
cccgagaaccttggggaggtggcagagaagctggaacagctcatgttagaaggaaataaa
atatcaggaatgtgttccccactgagcctgaaagagctgaagattttgaaccttagtaaa
aaccacatttcatccctatcagaggactttcttgaggcttgtcctaaagtggaaagtttc
agtgctagaatgaattttcttgctgctatgccttttttaccttcttcgatgacaagcata
aaattatctcaaaacagatttacatgtgttccagaggcaattttaaatcttccacatttg
cgatccttagatatgagcagcaatgatattcagtatctaccaagccctgcccactggaaa
tctttgaacttaagggagctcttgtttagtcataatcagatcagcatcttaaacttgagc
gagaaagcacatgcatggtctagagtagagaaactacatctttctcataataagctcaaa
gagattcctcccgagattggctgtcttgaaaacctgacctctcttgatgttagttacaac
ttggaactgagatcctttcccaatgaaatggggaaattaagcaaaatatgggatcttcct
ttggatgaactgcgtcttaattttgattttaaacatgtaggatgtaaagccaaagacatc
ataaggtttcttcaacagaggttaaaaaaggctgtgccctacaaccgcatgaaacttatg
attgtgggaaataccgggagtggtaaaaccaccttgttgcagcagttaatgaaaaccaag
aaatcagaccttgggatacagagtcccacggttggcatagatgtgaaagactggcctatc
ccactaaaaggcaaaaggaagaaagacctcatcctaaatgtgtgggattttgcaggtcgc
gaggaattctacagcactcacccccacttcatgaccccgcggtccctgtacctcgctgtc
tacgacctcagcaaagggcaagccgaggtcgatgcaatgaagccttggctcttcaatata
aaggctcgtgcttcttcctccccggtgattcttgttggcacgcacttggatgttgcagac
gagaggcaacgcaaagcctgtatcagtaaaataaacaaggaactcttgaacaagcgaggg
tttcctgcgatacgtgattaccactttgtgaacgccaccgaggaatcggacgctttggca
aaacttcggaaaaccatcataaacgagagccttaatttcaagatccgagatcagcctgtt
gtcgggcagctcattccagactgctatgtggaacttgagaaaatcattttatcagagcgt
aaaaatgtgcccattgaatttcctgtaattgaccggaaacaattattacaacttgtgaaa
ggaaatcaactgcagttagatgaaaatgagcttcctcatgcaattcactttctaaatgaa
tcaggggtccttcttcattttcaagacccagcactacaattaagtaacttatattttgtg
gaacccaagtggctttgtaaagtcatggcacagattttgacagtgaaggtggaaggttat
tcaaagcatcctaaaggaattatttcacgtagagatgtggaaaaatttctttcaaagaaa
aagagatttccaaagaactacatgcaccagtactttaaactcctcgaaaaatttcagatt
gccttgccaataggagaagaatatttattggttccaagcagtttgtctgaccacaggcct
gtgatagagcttccccattgtgagaactctgagattatcattcgactgtatgaaatgcct
tattttccaatgggattttggtcaaggttaatcagccgattacttgaaatttcaccttac
atgctttcaggaagagaacgagtacttcgcccaaatagaatgtactggcggcaaggcatc
tacttgaattggtcccctgaagcttattgtctggtaggatctgaagtcttggataatcac
cctgagagtttcttaaaaattacagttccttcctgtagaaaaggctgtattcttctgggc
caagttgtggaccacatcgattctctcatggaagaatggtttcctgggttattagagatt
gatatttgtggtgaaggagaaactttgttgaagaaatgggcactatatagttttaatgat
ggcgaagaacatcaaaaaatcttacttgacgacctgatgaagaaagcagaagaaggagac
ctcctggtaaatccagatcaaccaaggctcaccattcccatatctcagattgctcctgac
ctgattttggctgaccttcctagaaatattatgttgaatagtgatgaattggaatttgaa
caagctccagagtttctcttaggtgatgggagttttggatcggtttatcgagcgacgtat
gaaggggaagaagtggccgtaaagattttcaataaacatacgtcacttagactgttaaga
caagagctggtggtgctttgccacctccaccaccccagcttgatatctttgctggcagct
gggattcgtcctcggatgttggtgatggagctggcctccaagggttccctggaccgcctg
ctgcagcaggacaaagccactctcacgagaactctgcagcacaggatcgcactacacgtg
gctgacggcttgaggtacctccactcggccatgatcatttaccgtgacttgaagccccac
aacgtactgcttttcacgctgtatcccaatgctgccatcattgccaagatcgctgattac
gggatcgctcagtactgctgccgaatggggataaaaacatcagaaggcacaccagggttt
cgtgcacctgaagttgctagaggaaatgtaatttataaccaacaggctgatgtttattca
tttggcttactactgtatgacattttcacatctggaggtagaatagcagacggtttgaag
tttccaaatgagtttgatgaattggcaatacaaggaaaattaccagatcctgttaaagaa
tatggatgtgccccatggcctctggttgagaagttaattgaaaggtgtttaaaagaaaat
cctcaagaaagacctacttctgcacaggtctttgacattttgaattcagctgatttactc
tgcctgatgagacatatcgccatccataaaaaccttactgtggagtgcgtggtcgccacg
agtcattccagcaggaacgcgagtgtctggctgggctgtgggaacgcagacagaggacag
ctctcctttcttgactttaccaccgaaagactcacttctgaggaagttactgatagtaga
atactgtgcctcgccttggtgcatctacccgttgaaaaggaaagctggattgtgtctggg
acgcagtccggtgtgctgcttgtcattaacactgaagatggaaataagaggcacaccctt
gaaaggatgactgattccattacttgcttgtattgcaattcctcttccaggctgagcaag
caaaagaattttcttttggtgggaactgctgatggcaagttagcaatttttgaagataaa
actgttaagtgtaaaggagctgctcctttgaagatactcactataggaaatgttagcact
ccactcatgtgtttgagtgaatcagtgaattcaagtgaaagaaacattatgtggggagga
tgtggcacaaaacttttctcgctttctgatgatttctccattcagaaactcattgagacc
aggacaaatcagctgtttccttctgcagatttcagtgattccaacatcatagcagtggtg
gtagacacagctgtctacattgcgaagaaaaatagcccgcttgtggaagtgtgggataag
aaaactgataaactgtgtgaactaatagactgtgtgcactttttaaaggaggatgtggga
aaagcaaacaaggaagctaaacacaaaatgcattattctgggagagtgaaaactctctgc
ctccagaagaacacggctctctggatcgggaccggaggaggctccgtgttgctcctggat
ctgtcaactcgccggctgatacgtaggatccacagctatgattctgtcagagtcatgatg
acagcgcagttaggaagccttaaaaatgccatgttgattttggggtattcccagaaaagt
actgaaggcgtgcaacaccagaaagaattacagtctttcttgtctatttgggacatgaat
cttccacatgaagtgcaaaatttagagaaacatattgaagtaagaaaagaattagctgaa
aaaatgagaagaatatctgttgagtaa
DBGET
integrated database retrieval system
