Sturnira hondurensis: 118995970 Help Entry 118995970         CDS       T07222                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism shon  Sturnira hondurensis Pathway shon04064   NF-kappa B signaling pathway shon04066   HIF-1 signaling pathway shon04145   Phagosome shon04151   PI3K-Akt signaling pathway shon04217   Necroptosis shon04613   Neutrophil extracellular trap formation shon04620   Toll-like receptor signaling pathway shon04621   NOD-like receptor signaling pathway shon04936   Alcoholic liver disease shon05132   Salmonella infection shon05133   Pertussis shon05134   Legionellosis shon05135   Yersinia infection shon05140   Leishmaniasis shon05142   Chagas disease shon05144   Malaria shon05145   Toxoplasmosis shon05146   Amoebiasis shon05152   Tuberculosis shon05161   Hepatitis B shon05162   Measles shon05164   Influenza A shon05170   Human immunodeficiency virus 1 infection shon05171   Coronavirus disease - COVID-19 shon05205   Proteoglycans in cancer shon05235   PD-L1 expression and PD-1 checkpoint pathway in cancer shon05321   Inflammatory bowel disease shon05323   Rheumatoid arthritis shon05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:shon00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     118995970 (TLR4)    04066 HIF-1 signaling pathway     118995970 (TLR4)    04151 PI3K-Akt signaling pathway     118995970 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     118995970 (TLR4)   09143 Cell growth and death    04217 Necroptosis     118995970 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     118995970 (TLR4)    04620 Toll-like receptor signaling pathway     118995970 (TLR4)    04621 NOD-like receptor signaling pathway     118995970 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     118995970 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     118995970 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     118995970 (TLR4)    05161 Hepatitis B     118995970 (TLR4)    05171 Coronavirus disease - COVID-19     118995970 (TLR4)    05164 Influenza A     118995970 (TLR4)    05162 Measles     118995970 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     118995970 (TLR4)    05135 Yersinia infection     118995970 (TLR4)    05133 Pertussis     118995970 (TLR4)    05134 Legionellosis     118995970 (TLR4)    05152 Tuberculosis     118995970 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     118995970 (TLR4)    05144 Malaria     118995970 (TLR4)    05145 Toxoplasmosis     118995970 (TLR4)    05140 Leishmaniasis     118995970 (TLR4)    05142 Chagas disease     118995970 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     118995970 (TLR4)    05321 Inflammatory bowel disease     118995970 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     118995970 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     118995970 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:shon04131]     118995970 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:shon04054]     118995970 (TLR4)    04090 CD molecules [BR:shon04090]     118995970 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:shon00536]     118995970 (TLR4) Membrane trafficking [BR:shon04131]  Endocytosis   Phagocytosis    Toll-like receptors     118995970 (TLR4) Pattern recognition receptors [BR:shon04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    118995970 (TLR4) CD molecules [BR:shon04090]  Proteins   118995970 (TLR4) Glycosaminoglycan binding proteins [BR:shon00536]  Hyaluronan   Cell surface receptors    118995970 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_1 LRR_14 TIR_2 LRR_5 LRR_6 LRR_9 LRR_Zer-1 LRR_R13L1-DRL21 LRR_EndoS ThsB_TIR LRR_LRWD1 Motif Other DBs NCBI-GeneID:  118995970 NCBI-ProteinID:  XP_036915046 LinkDB All DBs Position Unknown AA seq 840 aa AA seqDB search MMSPTRLAGTLIPAMAFLSCLRPESWDPHVQVAPNITYQCMKLKFYKILDNISTSAKTLD LSFTPLRCLGNHSFSRFPELQVLDLSRCDIEMIADNAYQGLHRLSTLILTGNPIRHLAMG AFSGLSSLQILVAVETHLASLEVFPIGHLQTLKELNVAHNHINSFKLPEYFSNLTNLERL DLSNNNIQNIRHEDVQVLRQMPTFKLSLDLSLNPLDFIQPGAFEKIELHELTLRSNFNST DVMKTCIQGLGGLKVNRLVLGEFKNERIIPEFDKSSLKGLCNLTTEEFRIAFFDNFPEDD LGFLNCLANVSTISLVNLRLDMLGTPPKDFKWRNLKLTNCYLKHFPRLELDFLKEFVFTD NKGISLFTDIHLPILEFLDLSRNGLSFKGCCHHDDFGTTRLKHLDLSFNDVITMSSNFLG LEQLEYLDFQHSNLKQASDFSVFLSLKKLLYLDISHTNTRVVFRGIFDGLVSLQVLKMAG NNFEDDFLPNIFTDLTNLTFLDLSNCQLEQVSQEAFGSLPKLQLLNMSHNNLVSLDTLPY KHLPLQILDYSFNHIVAAKSQELQYLPSSLVSLNLTKNKFACVCEHISFLQWVRDHRNLL GGAEQMMCVKPLEMEGMSVLSFRNATCQMSKTIIGVSVISVLVVSVVAVLIYKFYFHLML LVGCKKYGRGECTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSHAGIIFVVLQKLEKSLLR QQVELYRLLSRNTYLEWEDGVLGRHIFWRRLKKALLDGKSWSPEGTEDAESSQDEATTST NT seq 2523 nt NT seq  +upstreamnt  +downstreamnt atgatgtctcccacccgcctggctgggacgctgatcccagccatggcctttctctcctgc ctgagacctgagagctgggaccctcacgtgcaggtggctcctaacatcacttaccagtgc atgaagctgaagttctacaaaatccttgataacatctccacatcagccaagacactggac ctgagctttaccccgctgaggtgtttaggcaaccatagcttctccaggttcccagaactg caggtgctggatttgtccaggtgtgacattgagatgattgcagataacgcatatcaaggc ctacaccgcctctccaccttgatattgacgggaaaccctatacggcatttagccatggga gccttttctggactctcgagtttacagatactggtggctgtggagacacacctggcatct ctagaagtcttccccattggacacctgcaaactctgaaggagcttaatgtggctcacaat catatcaattccttcaagttacctgaatatttttctaacctgactaacctggagcgcttg gacctttctaataacaacatccaaaatattcgtcatgaagatgtacaggttctacgtcaa atgcccacattcaaactctctctagatctgtccctcaaccctttagactttatccaacca ggtgcctttgaaaaaattgagctccatgaactgactttgagaagtaatttcaatagtacc gatgtaatgaaaacttgtattcaaggtctgggtggtttaaaagtcaatcggttggttctg ggagaatttaaaaatgaaaggatcataccagagtttgacaagtcttccctgaagggactg tgcaatttgactactgaagaattccgaatagcattcttcgataacttcccagaggatgac cttggctttttaaattgtttggcaaatgtttctacaatttctctggtgaatctgcgttta gacatgttaggaactcctccgaaagacttcaaatggcgaaacttaaaattgactaattgt tatttgaaacattttcccagactggagcttgactttctcaaagagtttgtttttactgac aacaaaggtatatccctttttactgacattcatctaccgatcctggagtttctagatctc agtagaaatggcttgagcttcaagggttgctgtcatcacgatgattttgggacaaccaga ctgaaacacttagatctgagcttcaatgacgttattaccatgagttcaaacttcctgggc ttagagcaactagaatatctggatttccagcattccaacttgaaacaggccagtgatttt tcagtattcctatcactcaaaaaacttctttaccttgatatttctcatacgaacacacga gttgtcttccgtggaatctttgatggcttggtcagcctccaagtcttgaaaatggctggc aataatttcgaggatgacttccttccaaatatcttcacagacttgacaaacttgaccttc ctggacctctctaattgtcaactagaacaagtgtcccaggaggcatttggctcactccct aaacttcagttgctaaatatgagtcacaacaacctcgtttccttggatacacttccttat aaacatctccctctccagattctggattacagttttaatcatatagtggctgccaagagt caagagctacagtatttaccgagtagcctagtttccttaaatcttactaagaataagttt gcttgtgtttgtgaacacattagtttcctgcagtgggtccgggaccacagaaatctcttg gggggagctgagcaaatgatgtgtgtgaaacctttagagatggagggtatgtctgtgctc agttttagaaatgccacctgtcagatgagcaagactatcattggtgtgtccgttatctct gtactggtggtatctgtggtagcagttctgatctataagttctatttccacctgatgctt ctggtgggctgcaagaagtatggccgaggtgagtgtacctatgatgcctttgttatctac tcgagccaggatgaggactgggtgaggaatgagctggtcaaaaacttggaggagggggtg cccccctttcagctctgccttcactatagagactttattcctggtgtagccattgccgcc aacatcatccaggaaggtttccacaaaagccgcaaggtcatcgttgtcgtgtcccagcat ttcatccagagccgatggtgcatctttgagtatgagattgcccagacctggcaatttttg agcagtcatgccggcatcatctttgtcgtcctgcagaagttggagaagtccttgctccgg cagcaggtggagctgtatcgccttctcagcaggaacacttacctggagtgggaggacggt gtcctggggcggcacatcttctggagacgactcaaaaaagccttgctggatggtaaatcg tggagtccagaaggaacggaggatgcagaaagcagccaagatgaagcaacaacctccacc tga

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