Sarcophilus harrisii (Tasmanian devil): 100914919 Help Entry 100914919         CDS       T02286                                  Symbol PCLO Name (RefSeq) protein piccolo isoform X4   KO K16882   protein piccolo Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr04911   Insulin secretion Brite KEGG Orthology (KO) [BR:shr00001]  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     100914919 (PCLO)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:shr04131]     100914919 (PCLO) Membrane trafficking [BR:shr04131]  Exocytosis   Calcium ion-dependent exocytosis    Others     100914919 (PCLO) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-piccolo C2 PDZ FYVE_2 Siva Motif Other DBs NCBI-GeneID:  100914919 NCBI-ProteinID:  XP_023360506 LinkDB All DBs Position 5:138958606..139472132 Genome browser AA seq 5072 aa AA seqDB search MGNEASLEGEGLPEGLTAAAAAAAAAAAGGGDGGAGSTLHTMIPAGMEADLSQLSEEERR QIAAVMSRAQGLPKGNVPPAAAEPPSMQRKQEFDSSHHPKQPGKPPDPGRPGQPTLSKSR TTDTLRTEQKSPGRSPSTTSLRESKSRTDFKEEQKSSIMPSFLTESNPLSAVSSVVNKFN PFDLISDSDVSQEETTRKQKVVQKEPAKPEGITKPISQQQSPKPITKPQGPPKVTSQPAG TTKPIPPQQPGKTKPQSVGTGKPTQILGSTEETSRSEQAKPPVQQRGPTKTQPDPSKSDP AKLVSQGPSKAYSQQPGPTKSPAQQPDATKPPAQQPGPTKPPTQQPGPMKPPTQQPGPMK PPAQKPGPTKPPTQQPGPTKPPPQQPAPTKLTIQQTGASKTPTQQPGPSKTPTQQPGPSK PPTQQPGITKPPAQQLEPTKPPSQQPASTKLLGQQTTKPSSQQAEPGKPLQPQPTSSPSA ALTSAQGPPKTFCPLCTTTELLLHTPEKANYNTCTQCQTIVCSLCGFSPPHITEVKEWLC LNCQMQRALGGDLAPVPPTPQQKPKVSPAVTASSVTKPVPPSQQTSLKKDVAPKPDLSKS PEIKKPPPLTKQPSIPGSPPAKAKQPSPRESVTQPTPHPEPSLKSEQAKVPMADDKSKQP KTQKPPADAGASSLVAMKPDVSGSKMQSQVQEKTAQPPKTDSAKSTQIIPPVGDKEVPPD SKGPSRTPSDSKPTSQPGMISESKIQKQVDPVQKKEDPKKAQTKMSPKPDAKQMPKGSPT LPGTKPSPGQPTLTAQQPPKTQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS IFSQASNLISTAGQAGTQAQGMPGAPTKQPPPPSHPPVSQVPPKPTSQTPQTVPKTTPVK KDTKAPTAEKTEVPKPEQVAPVKGTEPEKKPLPTKESKPQMVEPQKAAGPLESEKPTKPK STCPLCKIGLNVGSKDPPNFNTCTECKNVVCNLCGFNPTPHLTEVQEWLCLNCQTQRAIS GQLGDMGKVPPSIPPISSEIVQKPSAIPQPQPPVTEEISPKISPMPAQVTEKKKEQEAQK EDEKVKEIPSLEKKPPLISTDEKHEESKLKDKIIDSDDLEEKPKKGELQEIMKPEVPADK EKSLDQELPKEVHVEKQAEIKTAPGIPQSLPKEEEKTQKKDDVLQTTPLVKPDQVETVKE KIEKEDDKSDTSSSQQQKSPQGLSDTGYSSDGISGSLGEIPSLIPGDEKDLPQEIKKDSH SQESSPTSPSDLAKLESTVLSILEAQANSLVEEKSEKKKELYGGLPEQPKDQQKTKDFPV TLESYSSEEEDIKEVQEEKKDVLVKAEKDSIPSIKAVREKTDFVDDVTARRQRYDSLEDS SESENSPVSRRKRRASVGSSSSDEYKQEDSQGSGDDEDFIRKQIIEMSADEDASGSDDDD FIRKQLKEISVSESQKKEETKGKGKGIVGKHRRLTRKSSTSFDDDAGRRHSWHDEDDETF DESPELKYRETKSQESEELTVTGGGGLRRFKTIELNSTVTDKYSEDSVQKKTSLYFDEEP ELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQRKS RHRSHGPLLPTIEDSSEEEEMREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQR RRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKII EVQKVYKLPTAVSLYSPTDEQSITIQKDSGQKVLKSAEEMYEEMMHKSHKSKVFPTPTEK DEVFEKEPLYGGMLIEDYIYESLVEDTYNGAVDSSLLTRQEEDSEFIHPGGRERKMRIPE EIYEDPMKKISDLQKEFYELESLHSMVPQEDIVSSSYIIPESHEIVDLGTMVTSTSEEKQ LLDADAAYEELMKRQQMQLTPGASPTQSATEHDLTEPAIDFDRMPDTSLTSSILSGASLT DSTSSTTLSIPDVKITQHFSPEEIEDEYITDYTREIQEIIAHESSILAYSELSESATSVL PSDTPSLTSSISSVCTTDSSSPITAPETTTAVFADTVDQLAKFQDSEKIPLPPFPVDTKV YSRTDISLDQTAQPSSKAIDDHVVISLPDVPRSVMVPEEFKPKPSVSDSFSVDSSVSEED AVRKTKSKNGNGGMLETYKDKRKAPVPLLRRISSVDSGPVQPPSSIIAVPVSDQMSTVST ISREVTDTISQLPSMTSIPAVTPRTPLLWRSSSLDSSAQPPLVPPAPAPPAPPAPAPPAP APPAPPAPPAPLPPPPPPPPLPPPTPPKPAIYPKKKLIKAPPVTSAVIVPSVDTVATVEA TASPKNNLTPVTKVYTPAPPPVPPKPSSIPSGLVFTHRPVEGTKPPIAPKPTIPQPPITT PLPVDTHPKPAGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLETYVVIT LPSEPGTPTDSLTSQAVTSWPLGSPSKELVSMEPVFTTVLPVTGEEIQSMSDQSLYTSGA LQPFSAAPVMTQPSFHVAPGSVTPFLSSELSKTLVSLADSTIPSVDSNSVSITIPPEPVA QEPLALEKPRYKEDGKFQHFGDVIDLRMVSKVDGEITGSCMDLSASPGDVRRQTTASESY GRQISTVQPAIINLSATSTVVTPLSLVTETMAVVTCTTSLSYSTSTESLVGTDHSMMTPL QLTTSKHAEPTYRKTSVQVFPTLREEAPINLSLSTSGHVVTMPATKPITVPPPSVTNGWA DLSTSQGPQDDGAVDLSTTKSHRTVVTMDESTSGVVTTVIEDDEKPVDLTAGRRAVCCDV VYKLPFGRSCTTQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLADTG VFLYKSKNTFDYTGGVDTAVDLTSGRITTGEVMDYSSKTTGPYPETRQVISGSGIGTPQY STARMTPPPGSPYGMGTVLRSSNGVVYSSVATPVPSTFAITTQPGSIFSTTVRDLSGIHT TDAITSLSALQQSQPLPRSYGFLTTGASDKDSSVTAIEIETSLQTLPVESLPAEAIDVIP TLTTASEVFPEVLGDDSALAIGTEEDKQQQLDLERELLELEKIKQQRFAEELEWERQEIQ RFREQEKFMVQKKLEELQSMKQHLLLQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQL HQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYPAVESNQFWPTEDVTTTASAVV AIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEMPLTDIVVKDEKQLKKRTSGAKMRGQY DELEEAVGEDPRCFKKIVDSGVQTDDEDGADRSYANRRRRSKKSVDTSVQTDDEDQDEWD VPSRSRRKSRPGKYSDSTSEIDKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRAQV DAKVEIIKHISAPEKTYKGGSLGCQTETDPDAQSPQFLSATSSPKDKKRPTPLEIGYSSH LRADSTLQLAPSPPKSPKVLYSPISPISPGKALESAFVPYEKPITDDISPQKILHPDMAK VPPASPKSVKMMQRSMSDPKPLSPTAEESSRVHFQYTEGYLTKGSQTMTASGSQKKVKRT LPNPPPEETSSGTPSAYSTMGSVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKK QAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTR PTRIESQHGLERPRTAPQTEFNQFMPPQTQTESQLVPPTSPYTQYQFSSPALPTQAPTQY TQQSPYQQQPLYHQQVSPYQTQPTFQTVATMSFTPQTQPPPTPQPSYQLPSQMMVIQQKP RQSTLYLEPKITSNYEVIRNQPLMIAPVSTENTYAVSHLGSKYNSLDLRIGLEERSSIAG SPISSISADSFYADIEHHTPRNYLLIDDIGELTKGTASLSTAFSLHDKDLTKTDRLLQTT ETRRTQEVTDFLSPLQTSSRLHSYVKADEDPMDDPYELKLLKHQIKQEFRRGAESLDHLA GLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQAKHKKSLIDPKMSKF SPIQESRDLEPDYSSYMTSSSPSVGGISSRARLLQDDITFGLRKNITDQQKFIGSSLTSS LGTGLGTLGSTIRSALQDEADKPYSSGTRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQ EAEALDVAFSHVTPSGRTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAG PLPPISADTRDQFGSSHSLPEVQQHMREESRTRGGYDRDIAIFMDDFQHAMSDSEAYHLR REETDWFDKPRETRLENGHGLDRKLPERLIHSRPLSQHQEQMNGKPTQYIFPHARIKIMR DLKDHTVSGNGLGIRIVGGKEIPGNSGEIGAYIAKILPGGSAEQTGKLIEGMQVLEWNGI PLTSKTYEEVQSIINQQSGEAEICVRLDINMLSDSENPQHLELHEPPKAVDKAKSPGVDP KQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAASSAVPSPGQPGSPSVSKKRHSSK PTDATKSVSHPITGEIQLQINYDKHLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGR GAEYKRRTKYVQKSLNPEWNQTVIYKNISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIE LSSTSHLDNTPRWYPLKEQTESIEHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQV PTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRLQ PTAHKSGQSNHTRKQHRHSIAGVLPIQRTQSDNLPPPANDNKDPSQLALRKVMSDGPVKP EGARPTNHRPAESSVSTGSSASSFGSGYSVDSEGGSSTAGETNLFPIPRVGKMGQNGQET AKQPGVGLTDAEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLY VKLYVVNISTQKRVIKKKTRVCRHDREPSFNETFRFSLNPAGHSLQILLVSNGGKFMKKT LIGEAYIWLDKVDLRKRIVNWHKLLVSPTQTH NT seq 15219 nt NT seq  +upstreamnt  +downstreamnt atgggcaacgaagcgagcttggaaggggaaggtctccctgaagggctgacagctgctgcg gcggcggcggcggcggcggcagccggaggaggggacggcggggcggggagcaccttacac accatgatcccggccggcatggaggcggacctgagccagctgagcgaggaggagaggaga cagatcgctgctgtcatgtcaagggcgcaggggctgcccaaaggaaacgtcccccccgcc gcagcggaaccaccttctatgcaaaggaaacaagaatttgatagcagtcatcatccaaag caaccagggaaacctccagatcctgggcgtcctggacaacccactctcagtaaaagtaga acaacagatactttgagaactgagcagaaatctcctggaagaagcccttctacaactagc ctgagagaatctaaatctagaacagattttaaagaagaacaaaagtcaagtattatgcct agctttctcacagagtctaacccattaagtgctgtctcctctgttgtaaataaatttaac ccgtttgatttgatatcagactctgatgtatcccaggaagaaaccactaggaaacaaaaa gttgttcagaaggaaccggcaaaacctgaaggtatcacaaaacccatatctcaacagcaa tcccctaaaccaattacaaagccacaagggcctcccaaagttacatctcagccagctggt actaccaaacccatacctcctcaacaacctggaaaaactaaacctcaatctgttgggaca ggaaagccaactcaaattttagggtctacagaagaaacttcacgatcagaacaggcaaag ccaccagttcaacaacgaggtccaaccaagactcaaccagatccttcaaaatcagatcct gctaaattagtatcacaaggcccatctaaagcatattcccagcaaccagggcctacaaaa tcacctgctcaacaaccagacgcaacaaaaccacctgctcagcagcctgggccaacaaaa cctcccactcagcagcctgggccaatgaaacctcccactcagcagcctgggccaatgaaa cctcccgctcagaagcctgggccaacaaaacctcccactcagcagcctgggccaacaaaa cctccccctcaacagccagcgcccacaaaactgaccattcagcagactggggcttcaaag acccccacccagcagcctgggccttcaaagacccccacccaacagcctgggccttcaaaa ccccctacccagcagccagggatcacaaaacctcctgcccaacagttagaacccacaaaa cccccttctcaacagccagcctcaacaaaactccttggtcagcagactacaaaaccctca agccaacaagcagagcctggaaaacctttgcaaccacaaccaacttcctccccatctgca gcactgacgtcagcccagggtccccccaaaaccttttgtcctctttgtactaccacggaa cttctgctccacactccggagaaggccaattataatacttgcactcagtgtcaaacaatt gtctgtagcctgtgtgggttcagtcccccacatataacagaggttaaagagtggctttgt ctaaactgccagatgcaaagagcactgggtggtgatttggccccagttccaccaactcct cagcagaaaccgaaggttagccctgcggttacagcatcttcagtgactaaaccagtccct ccatcccagcaaacttcccttaaaaaggatgttgcccctaaaccagatctttcaaagtcc cctgagattaaaaaacctccgccactcacaaagcaaccatccattccaggctctcctcca gcaaaagccaagcagccttcccccagagagtctgtaacccagccaacccctcacccagag ccttctctcaaatctgagcaagccaaggtaccaatggctgatgacaaatctaaacagcca aagacacagaagcctccagctgatgctggggcttcctcgttagttgcaatgaaacctgat gtctcaggctccaaaatgcaatcacaggttcaggagaaaacagcacaacctcctaaaaca gattctgccaaatcaacacaaattatcccacccgtgggggataaagaagtcccacctgat tctaaaggcccatcacgtactccatctgattccaaacccacttcacaacctgggatgatc tcagagagtaaaattcaaaaacaagttgatccagttcaaaaaaaggaagaccctaagaaa gcacaaaccaaaatgagccccaaaccagatgccaagcaaatgccaaaaggatcgcctact ctcccaggcacaaagcctagtcctggacaacccacacttacagcccagcagcccccaaag acccaagaacagtcgagacgtttcagtcttaatctgggaagtatcacggatgccccgaaa tcgcagcccacaactccccaagagacagtcactgggaagctatttggatttggagcttca atctttagccaggcatcaaatttaatttccacagctggtcaagcaggaactcaagcacaa ggtatgccaggggctccaaccaaacaaccccctcccccttcacatccacctgtatctcag gtaccacctaagcccaccagtcaaactccacaaacagttcctaaaaccacacctgttaaa aaggacacaaaagctccaactgctgaaaaaactgaggtgcctaaacctgaacaggttgcc ccagtcaaaggcacagaaccagaaaagaagcctcttcccacaaaagagagcaaaccgcaa atggtggaaccgcaaaaggctgctggccctctagaatcagaaaagcccaccaaaccaaaa tctacttgtcccctttgtaaaattggcctaaatgtgggttctaaggatcctcccaacttt aatacttgtacagaatgcaagaatgtggtatgcaatctctgtggatttaatccgacacca catttaactgaggttcaagaatggctatgcttaaattgtcagactcagagagcaatatca ggacaacttggggacatgggcaaagtgccaccttcaatcccacctatttcttcagagatt gtacaaaaaccatcagctatacctcagcctcagcctcctgtgacagaagaaatatccccc aaaatatccccaatgcctgcccaagtaacagaaaaaaagaaagaacaagaagcacaaaaa gaagatgaaaaagtaaaggaaataccttcacttgaaaagaagcccccattgataagcaca gatgaaaagcatgaggaaagtaaattgaaagacaagattatagactctgatgatttggag gaaaagcccaaaaagggagagttgcaagaaataatgaaacctgaggtgccagctgataaa gaaaaatccttggaccaggaacttcctaaagaagtacatgtggaaaaacaagcagagatc aagacagcacctggaattccccagagtctacccaaagaagaggagaaaactcagaaaaaa gatgatgtactacagacaacaccattagtaaaaccagatcaagtggaaacagtgaaagaa aaaatagaaaaggaagatgacaaatcagatacatcaagttctcagcaacagaaaagccct caaggtttgagtgacacaggatattcttctgatggaatatcaggttcccttggtgaaatt ccaagtcttattcctggtgatgaaaaggacttgccacaagaaattaaaaaagattctcat tctcaagaaagtagtcctacaagtccttctgatctagcaaagttagaaagtactgttctg tccattttggaagctcaagcaaattcacttgttgaagaaaaatcagaaaagaaaaaagaa ttgtatggtgggcttcctgagcagcccaaagatcaacagaaaactaaggattttcctgtc acactagaatcttatagttcagaagaagaggatatcaaggaagttcaagaagaaaagaaa gatgtccttgtaaaagctgaaaaagacagtatcccttccataaaggccgtcagagaaaaa actgactttgtagacgatgtgacagctagaaggcagcgttatgattcactggaagatagc agtgaaagtgaaaactcccctgtctcacgaaggaaaagaagagctagtgttggttcatca agcagtgatgaatataagcaggaagacagtcaaggatcaggtgatgatgaagatttcatt agaaaacagatcatagagatgagtgccgatgaagatgcctctggttcagatgatgatgat ttcatcaggaaacaactcaaagaaatcagtgttagtgagagccagaagaaggaagaaaca aaaggaaaggggaaaggaatagttgggaaacacaggagactcaccagaaaaagtagtaca agctttgatgatgatgcagggagacgtcattcttggcatgatgaagatgatgagacattc gatgagagcccagaattaaaatatagagaaaccaaaagtcaggaaagcgaagaactcact gttactggtggaggaggtcttagaagattcaaaaccattgaactaaacagcacagtgaca gataaatattctgaagactctgtgcaaaagaaaacaagtttatattttgatgaagaacca gaacttgagatggaaagtcttacagattcaccagaggatcggtcacgaggagaaggatct tctagtctacatgcctccagtttcacacctggtacatctcctacatcagtgtcatctctt gacgaggatagtgacagcagtccaagtcacaaaaagggagagagtaagcagcgaaaatct agacaccgatcacatggtcctcttcttcccactattgaagattcttcagaagaagaggaa atgagggaagaagaagaattattaaaggagcaagaaaaacaacgtgaaatcgaacagcag caaagaaagagttccagtaaaaaatcaaaaaaagacaaagatgaacttcgggctcaaaga agaagagaaagaccaaagacaccacccagcaatctctctccaatcgaagatgcatctccc acagaagaattacgtcaggctgcagagatggaagagttgcatcgttcctcttgctctgaa tattctccaagcatagagtcagatccagaagggtttgaaattagcccagaaaaaataata gaagtacaaaaagtttataaactgcccacagctgtgtctttatattctccaacagatgag caatctattacaattcaaaaagatagtggtcaaaaggtattaaaaagtgctgaagaaatg tatgaagaaatgatgcataaatcccacaaatcaaaagtgtttccaacaccaacagagaaa gatgaagtatttgagaaggagcctttgtatggtggaatgctaatagaggattatatttat gaatctttggttgaagatacatacaatggtgctgttgatagcagtctattaacaagacaa gaggaggatagtgaatttattcatccaggagggagagagagaaaaatgagaattccagag gagatctatgaagatcctatgaagaaaatctcagatctgcagaaagaattttatgagcta gagagcttacattctatggtgcctcaagaagatattgtatcaagctcatatatcatccct gaaagtcatgaaattgtggatctaggtactatggtaacatcaacgagtgaagagaagcag ttattagatgcagatgcagcctatgaggaactcatgaagaggcaacaaatgcagctaacc ccaggagctagtccaactcaatcagccactgagcatgatctaacagagcctgcaatagac tttgacagaatgccagatacctcattgacatctagtattctctcaggagcctcacttaca gactcaactagtagtacaacactttctatcccagatgtgaaaataacgcagcacttttca ccagaggaaatagaggatgaatatataactgattataccagagaaattcaagagataatt gcccatgaatcatcaattttagcatactctgagctctcagaaagtgcaacatctgtgcta ccgtctgacacgccctctcttacatcatccatttcatcagtttgtacaacggatagctcc tcacctattactgctccagaaaccacaactgcagtttttgcagatactgtggaccaacta gctaaatttcaggattctgaaaagattccattacctccctttccagtagacacaaaagta tattcaagaacagatatatctttagatcagactgcccaaccctcttctaaagcaattgat gatcatgttgtaatttctcttcctgatgttccaaggtctgtcatggtacctgaagaattc aaaccaaagccatctgtttctgattctttttctgttgattcatctgtatcagaagaagat gcagtaagaaaaactaagagtaaaaatggaaatggtggcatgctggaaacttacaaggat aaaagaaaggcacctgtacctttactacgtagaattagctctgtagattctgggccggtc caaccaccttcaagtatcattgcagttccagttagtgatcaaatgtcaaccgtttctact atatctagagaagtgaccgatacaatatcacaattgccatctatgacttcaattcctgct gtgacacctagaacacctcttctttggagaagttcttctttggattcatctgcccaaccc ccacttgttcctcctgctccagctcctcctgctcctcctgctccagctcctcctgctcca gctcctcctgctcctcctgctccccctgctcctcttcctcctcctcctccacctcctcca cttcccccaccaactccacctaaacctgctatttatcctaaaaagaagttaataaaagct cctccagtgacatcagctgttattgtaccttcagttgacactgttgctactgtagaggct actgctagtccaaaaaataatttgacacctgtaacaaaagtatacacccctgcaccacct ccagttccacctaagccttcttcaattccatcaggacttgtatttactcacaggcctgtt gagggaaccaagcctccaattgctcctaaaccaacaattcctcagcctccaataactaca cctctgccagtggatacacatcccaaaccagcaggtttatccttaacttcaagtatgaca ttgaatttagtgacttcagcagattataaactgccatctcctacatctcccttgtcacca cattctaacaagtcctccccaagattttccaaatcattggagacttatgttgttataaca ttgccatctgaaccaggaactccaacagattctttaactagtcaggcagtgaccagttgg cctttgggatcaccttctaaggaactagtttcaatggagcctgtatttactacagttctt cctgtgacaggtgaagagattcaaagcatgtcagatcagagcctgtatacctcaggtgct ttacagcctttctctgctgccccagtcatgacacagccttcattccatgtagccccaggc tcagtaactccatttctctcaagtgaactgagcaaaaccttagtttcattggcagacagc acaattcctagtgttgattcaaatagtgtttctataacaattcctcctgaacccgtagct caagaacccttagcgttagagaaaccaagatataaagaagatggaaagtttcagcatttt ggagatgttattgatctacgcatggtatcaaaggttgatggtgaaataactggaagctgc atggacctgtctgcttctccaggagatgtgagaaggcagaccacagcaagtgagtcatat ggcagacaaatcagcactgtccaacctgctattataaatctcagtgcaacttcaacagta gtcacgcccctctccctggtcacagaaactatggctgttgtgacatgtacaactagccta agttatagcactagcacagaaagcctggttgggacagatcattctatgatgacacctctt cagttaacaacatcaaaacatgctgagcctacctacagaaaaacgagtgtccaggtcttc ccaacacttagggaggaagcaccaataaatttatctctaagtacttctgggcatgtagta acaatgcctgccaccaaacctatcactgtacctccacctagtgttaccaatggatgggct gatctctccacgtctcaggggccccaagatgatggtgcagtggacctcagtactacaaag tctcaccgtactgtagtcaccatggatgaatctacttccggtgttgtgacgactgtcata gaagatgatgagaaaccagtggatttgaccgcaggaagaagagcagtttgctgtgatgtt gtttataagttaccatttggaagaagttgtacaacacaacagcctgcaactactcttcca gaagatcgttttggttacagggatgatcactaccagtatgatcgatcagggccatatggt tataggggtattgggggcatgaagccttctatgtctgacacgaacttagctgatactgga gtttttctttataaaagtaagaatacctttgattatactggaggggttgatacagcagta gatctaacttctggaagaataactacaggtgaggtaatggattattcaagcaagaccaca ggtccttaccctgagactcggcaagttatttcaggcagtgggattggtacaccacaatat tctacggcaagaatgacccctccaccaggatccccatatggcatggggactgttttgaga tcctccaatggtgtagtctattcttcagtagcaactccagtcccttctacatttgctatc actactcagcctggctcaattttcagtactacagtgagggatttgtctggcattcacaca actgatgcaataacatctttgtctgctttgcaacagagccagccgctacctagatcgtat ggtttcctaactacaggagcatctgataaggacagttctgtgactgcaatagaaatagaa acaagcttgcaaactcttcctgtggagagtctccctgctgaggccattgatgttattccc actttgaccacagcatctgaggtgtttccagaagtcttgggagatgacagtgctcttgcc attgggactgaagaagataagcagcaacaacttgatttggagagagagctcttagagctt gagaaaattaagcaacagcgatttgctgaggagttagagtgggaacgacaggaaatacaa agattccgagagcaggagaagtttatggttcaaaagaaactagaggagttgcaatctatg aagcagcatctcttattacagcaagaagaagagaggcaagctcagtttatgatgaggcaa gaaacactagcacagcaacagctacaacttgagcaaatccagcaacttcaacagcaactt caccagcagctagaagagcaaaagatccgccagatataccagtataattatgatccttca ggaacagcttcaccacaaacaaccacggaacaagcaattctggaaggtcagtatccagca gtggagagcaatcagttttggcccaccgaagatgtcaccaccacagcttcagctgtagtg gccattgaaatcccacagagccaaggctggtatacagttcagtctgatggtgttactcaa tatatcgctccacctggtatactgagtactgtttctgaaatgcccttaactgatattgtt gtgaaggatgaaaagcaacttaaaaaaaggacttctggagccaagatgcgtggccaatat gatgagcttgaggaagctgtgggtgaggacccccggtgttttaaaaagatagtggacagt ggagtacaaaccgatgatgaagatggagccgacagaagttatgctaataggagaagaaga agtaaaaagagtgtggatacgagtgttcagactgatgatgaagatcaagatgaatgggat gtgcccagtagatcacggcgaaaatcacgtccagggaaatatagtgatagcacctctgaa attgacaaaactaaacccctttctaaggtatctagcatagcagttcagacagtggcagaa atatcagtgcagactgaaccagttgggaccataagaacgccttccatacgtgctcaagta gatgcaaaagttgaaataatcaagcacatttcagctcctgaaaaaacatacaaaggtgga agtttaggttgtcaaacagagacagacccagatgcacagagtcctcagtttttgagtgcc acatcttcacccaaagacaagaaacgtccaacgcctttagaaataggttattcatctcat cttcgggcagattccaccctacagctagcaccatccccaccaaaatctccaaaagtcctt tattcacccatttctccaatttcaccaggcaaagccttagaatcagcctttgtaccttat gaaaagcccattactgatgatattagtcctcagaaaatattgcacccagacatggcaaaa gttccaccagcaagtccaaagtctgtgaaaatgatgcagaggtcaatgtctgatccaaaa cctttgagtccaacagcagaagagagttccagagtgcattttcagtacacagaaggctac ttgaccaaaggctctcagactatgaccgcttctggcagccagaagaaagtaaagaggaca ctaccaaatccacctcctgaagaaacttcctcaggaaccccatcagcatacagcactatg ggatccgtttcccgaagaagaatctgcagaactaacactatggcaagagccaaaatcctt caggatatagatagagaacttgatcttgtggaaagggaatcggcaaaactcaggaagaag caagctgaactggatgaggaagaaaaggagatagatgcaaagttgcgttacttggaaatg ggaatcaaccgaagaaaagaagccttattaaaggaaagggaaaagagagagcgagcctac ctccagggagtagctgaggaccgtgattatatgtcagatagtgaagtaagcagcactcgg ccaacccgaatagaaagtcagcatggtttggagagacctagaactgccccccaaacggaa tttaatcaatttatgccaccccaaacacagacagagtctcagttagttccaccaacaagt ccttacacgcagtaccagttctcctcccctgctcttccaacccaagcaccaactcagtat acccaacagtctccttaccaacagcagcctttataccatcagcaggtttccccttatcag acccagcccactttccaaactgtggccacaatgtccttcacaccacaaacacagcctcca ccaacaccacagccttcatatcaacttccatctcagatgatggtcatacaacaaaaacca aggcaatctacattgtatttggagcctaaaataacatctaattatgaagtcattcgaaat caaccactgatgatagcaccagtttctactgagaatacttatgcagtgtcccatcttggt agtaaatataatagtttagatttaagaatcggtttagaggaaagaagtagcatagctgga agtccaatctcaagcatatctgcagattctttttatgcagatatagaacatcacacacca cggaattatctcctaattgatgatattggtgagcttactaaaggaacagcctcactgagt actgcatttagccttcacgataaggatttgacaaaaactgaccgcctccttcaaacaaca gagactcgcagaacccaagaagttacagattttctgtcacctttacagacttcttctaga ctacattcctatgtaaaagcagatgaagacccaatggatgatccatatgaattgaaactt ctcaaacatcagatcaagcaggaattccgtcgtggtgctgaaagtttagaccatctcgcc ggtctttcccattattaccatgcagacactagttataggcatttccctaaatcagagaaa tatagcattagtagactgacacttgaaaaacaggcagcaaaacaacttccagcagcaatc ctttatcaaaagcaagcaaagcataaaaaatcactaattgaccccaaaatgtcaaaattc tcaccaattcaagaaagcagagaccttgaacctgattactcaagttatatgacttctagc tctccatcagttggaggcatttcttccagggcaagacttcttcaggatgatattacattt ggccttaggaaaaatatcacagaccaacaaaaattcataggttcatcccttacttcatcc cttggaacaggcttgggcactttgggttccacaatccggtcagcattacaggatgaggca gacaagccttatagtagtggcactagatcaaggccttcttctcgaccatcttccgtctat ggacttgatttatctataaagagagattcgtcaagctcttctttaagattgaaggctcaa gaggctgaagctttggatgttgcttttagtcatgtcacaccctctggcagaactaagccc acaagtctgcctattagccagagcagaggaagaataccaattgttgctcagaactcagaa gaagaaagtcctttgagccctgttggccaaccaatgggaatggcaagagctgcagctgga ccactgccaccaatatctgctgataccagagatcagtttggatcaagtcattctttgcct gaagttcagcagcatatgagggaagagtcacggactcgaggaggctatgaccgggatatt gcaatcttcatggatgacttccaacatgccatgtcagacagtgaagcctatcacctacgt cgtgaggaaacagattggtttgacaagcccagggaaactcgtttagaaaatggacatggt cttgaccggaaactgccagaaagactgattcattcaagaccactcagccaacatcaagaa caaatgaatgggaagcctacacagtacatctttcctcatgcaagaataaaaataatgaga gaccttaaggatcatacagtttcaggtaatgggttaggaatcagaatagtaggtggcaaa gaaatcccaggaaatagtggagaaattggagcatatattgccaagatcctccctggtgga agtgcggagcagacaggaaagctaattgaaggaatgcaagttttagaatggaatggaatc cccctgacttctaaaacctatgaagaagtccagagtatcattaatcaacaaagtggggaa gcagaaatatgtgtaagactggatatcaacatgctctcagattcggagaatccccaacac ttagaactacatgaaccaccaaaggctgtagacaaagcaaaatcccctggggtagatcca aagcaactggcagctgagctccaaaaagtttctctccagcagtcaccattggttctttct tcagttgttgaaaaaggatcacatgttcactctggccccacatcagctgcatctagtgct gttcctagtcctggtcaaccaggatcaccctctgtgagcaaaaagaggcacagcagcaag cccactgatgcaacaaaatctgtctctcatccaattactggagaaattcagcttcaaatc aactatgacaaacaccttggaaatcttattatccacattcttcaagcaagaaatcttgtt ccacgtgacaacaatggatattctgatccttttgttaaagtttatcttcttccagggaga ggtgctgagtataagaggagaactaaatatgttcagaaaagtcttaatccagaatggaat cagacagtaatttataaaaatatctccatggaacagctcaagaagaaaacactggaagtg acagtctgggattatgatagattctcttccaatgactttcttggtgaggtattgattgaa ttatccagtacttctcaccttgacaatacccctagatggtatcctctcaaagaacagaca gaaagtattgaacacggaaagtcccattctagtcagagtagccagcaatctccaaaacca tctgtcatcaaaagcagaagtcatggaatcttccctgatccatccaaagatatgcaggta cctacaattgagaaatcccatagtagtcctgggagctcaaagtcatcctctgaaggccat cttcgctctcatggaccatcacgtagccaaagcaagaccagtgtcactcagacccatctt gaagatgcaggggccgccatagcagccgcagaagcagctgtgcaacagcttcgccttcaa ccaacagcacataaaagcggtcagtctaatcataccaggaagcagcacagacacagcata gcaggagtcctcccaattcaaagaactcagtctgacaatctgcctccaccagccaatgac aacaaagatccaagccagctggctctcaggaaggtgatgtctgatggaccagtcaagcca gaaggagcaagacctactaatcaccgacctgctgaaagctccgtctctaccggctcatct gccagcagctttggcagtggatatagtgtggacagtgaaggaggtagcagcactgcaggg gagactaatctatttcccattccaagagtaggaaagatgggccagaatggacaagagact gcgaagcagccaggagtaggattaacagatgctgaagctaaaacacaagtaatgggagaa atcaagattgccctgaaaaaagaaatgaaaacagatggagaacagctaatagttgagatc cttcaatgcagaaatatcacctacaaatttaagtctcctgatcatttaccagatttgtat gtgaagctgtatgtagtcaacatttctacccaaaaaagagtgatcaagaaaaagacaaga gtatgtaggcatgatcgggaaccttcattcaatgaaacatttagatttagcctgaatcct gctggacattctcttcagattttgctcgtctccaatggagggaagtttatgaaaaagaca ttaattggtgaagcttatatctggcttgacaaagtggatttaaggaaaagaatagtaaac tggcacaaactcttggtcagtcctactcaaacacattga

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