KEGG   Sarcophilus harrisii (Tasmanian devil): 100915116
Entry
100915116         CDS       T02286                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr03015  mRNA surveillance pathway
shr04022  cGMP-PKG signaling pathway
shr04024  cAMP signaling pathway
shr04114  Oocyte meiosis
shr04218  Cellular senescence
shr04261  Adrenergic signaling in cardiomyocytes
shr04270  Vascular smooth muscle contraction
shr04390  Hippo signaling pathway
shr04510  Focal adhesion
shr04611  Platelet activation
shr04720  Long-term potentiation
shr04728  Dopaminergic synapse
shr04750  Inflammatory mediator regulation of TRP channels
shr04810  Regulation of actin cytoskeleton
shr04910  Insulin signaling pathway
shr04921  Oxytocin signaling pathway
shr04931  Insulin resistance
shr05031  Amphetamine addiction
shr05034  Alcoholism
shr05168  Herpes simplex virus 1 infection
shr05205  Proteoglycans in cancer
shr05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:shr00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    100915116 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    100915116 (PPP1CA)
   04024 cAMP signaling pathway
    100915116 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    100915116 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100915116 (PPP1CA)
   04218 Cellular senescence
    100915116 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100915116 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100915116 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100915116 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100915116 (PPP1CA)
   04921 Oxytocin signaling pathway
    100915116 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100915116 (PPP1CA)
   04270 Vascular smooth muscle contraction
    100915116 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    100915116 (PPP1CA)
   04720 Long-term potentiation
    100915116 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100915116 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100915116 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    100915116 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100915116 (PPP1CA)
   05034 Alcoholism
    100915116 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100915116 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100915116 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:shr01009]
    100915116 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:shr03021]
    100915116 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:shr03019]
    100915116 (PPP1CA)
   03041 Spliceosome [BR:shr03041]
    100915116 (PPP1CA)
Enzymes [BR:shr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100915116 (PPP1CA)
Protein phosphatases and associated proteins [BR:shr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100915116 (PPP1CA)
Transcription machinery [BR:shr03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100915116 (PPP1CA)
Messenger RNA biogenesis [BR:shr03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     100915116 (PPP1CA)
Spliceosome [BR:shr03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100915116 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 100915116
NCBI-ProteinID: XP_031799114
Ensembl: ENSSHAG00000005510
UniProt: A0A7N4PAH1
LinkDB
Position
6:240333968..240336332
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactccatcatcgggcggctgctggaagtgcag
ggttcccggcccggcaagaacgtgcagctgacggagaacgagatccgcggcctgtgcctc
aagtcccgcgagatcttcctgagccagcccatcctcctggagctcgaggcgcccctcaag
atctgcggcgacatccacggccagtactatgacctgctcagattgttcgagtacgggggc
ttcccccctgagagcaactacctcttcctgggggactacgtggaccggggcaagcagtcc
ctggagaccatctgcctgctgctggcctacaagatcaagtaccccgagaacttcttcctc
ctccgcggcaaccacgagtgcgccagcatcaaccgcatctatggcttctacgacgagtgc
aagagacgctacaacataaagctctggaaaaccttcacggactgcttcaactgcctgccc
atcgcggccattgtggacgagaagattttctgctgtcacggaggactgtccccagacctg
cagtccatggagcagatccggcgcatcatgaggcccacagacgtgccagaccaagggctg
ctgtgtgacctcctgtggtcagaccccgacaaggacgtgcagggctggggggagaacgac
cgcggcgtctccttcaccttcggggccgaggtggtggccaagttccttcacaagcacgac
ctggacctcatctgccgggcacaccaggtggtagaagacggctacgagttctttgccaag
cggcagctggtcaccctcttctccgcccccaactactgtggcgagtttgacaatgcgggc
gccatgatgagtgtggacgaaaccctcatgtgctctttccagatccttaaaccggccgac
aagaacaaaggcaaatacgggcagttcagcggcttgaatcctggcggccgccccatcacc
ccaccccgtaactctgccaaggccaagaagtag

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