KEGG   Sarcophilus harrisii (Tasmanian devil): 100915297
Entry
100915297         CDS       T02286                                 
Symbol
PPP3CC
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X2
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04010  MAPK signaling pathway
shr04020  Calcium signaling pathway
shr04022  cGMP-PKG signaling pathway
shr04114  Oocyte meiosis
shr04218  Cellular senescence
shr04310  Wnt signaling pathway
shr04360  Axon guidance
shr04370  VEGF signaling pathway
shr04380  Osteoclast differentiation
shr04625  C-type lectin receptor signaling pathway
shr04650  Natural killer cell mediated cytotoxicity
shr04658  Th1 and Th2 cell differentiation
shr04659  Th17 cell differentiation
shr04660  T cell receptor signaling pathway
shr04662  B cell receptor signaling pathway
shr04720  Long-term potentiation
shr04724  Glutamatergic synapse
shr04728  Dopaminergic synapse
shr04921  Oxytocin signaling pathway
shr04922  Glucagon signaling pathway
shr04924  Renin secretion
shr05010  Alzheimer disease
shr05014  Amyotrophic lateral sclerosis
shr05020  Prion disease
shr05022  Pathways of neurodegeneration - multiple diseases
shr05031  Amphetamine addiction
shr05152  Tuberculosis
shr05163  Human cytomegalovirus infection
shr05166  Human T-cell leukemia virus 1 infection
shr05167  Kaposi sarcoma-associated herpesvirus infection
shr05170  Human immunodeficiency virus 1 infection
shr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
shr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:shr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100915297 (PPP3CC)
   04310 Wnt signaling pathway
    100915297 (PPP3CC)
   04370 VEGF signaling pathway
    100915297 (PPP3CC)
   04020 Calcium signaling pathway
    100915297 (PPP3CC)
   04022 cGMP-PKG signaling pathway
    100915297 (PPP3CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100915297 (PPP3CC)
   04218 Cellular senescence
    100915297 (PPP3CC)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100915297 (PPP3CC)
   04650 Natural killer cell mediated cytotoxicity
    100915297 (PPP3CC)
   04660 T cell receptor signaling pathway
    100915297 (PPP3CC)
   04658 Th1 and Th2 cell differentiation
    100915297 (PPP3CC)
   04659 Th17 cell differentiation
    100915297 (PPP3CC)
   04662 B cell receptor signaling pathway
    100915297 (PPP3CC)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100915297 (PPP3CC)
   04921 Oxytocin signaling pathway
    100915297 (PPP3CC)
   04924 Renin secretion
    100915297 (PPP3CC)
  09156 Nervous system
   04724 Glutamatergic synapse
    100915297 (PPP3CC)
   04728 Dopaminergic synapse
    100915297 (PPP3CC)
   04720 Long-term potentiation
    100915297 (PPP3CC)
  09158 Development and regeneration
   04360 Axon guidance
    100915297 (PPP3CC)
   04380 Osteoclast differentiation
    100915297 (PPP3CC)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100915297 (PPP3CC)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100915297 (PPP3CC)
   05170 Human immunodeficiency virus 1 infection
    100915297 (PPP3CC)
   05163 Human cytomegalovirus infection
    100915297 (PPP3CC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100915297 (PPP3CC)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100915297 (PPP3CC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100915297 (PPP3CC)
   05014 Amyotrophic lateral sclerosis
    100915297 (PPP3CC)
   05020 Prion disease
    100915297 (PPP3CC)
   05022 Pathways of neurodegeneration - multiple diseases
    100915297 (PPP3CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    100915297 (PPP3CC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100915297 (PPP3CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:shr01009]
    100915297 (PPP3CC)
Enzymes [BR:shr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100915297 (PPP3CC)
Protein phosphatases and associated proteins [BR:shr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100915297 (PPP3CC)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 100915297
NCBI-ProteinID: XP_012395492
Ensembl: ENSSHAG00000018431
UniProt: A0A7N4NPH4
LinkDB
Position
2:135073058..135197911
AA seq 535 aa
MSSRTRNKLSTTERVIKAVPFPPTRRLTIKEVFEDGKPRLDVLKSHLVKEGRLEEEAALK
IINDGGAILKSEKTMIELEAPITVCGDVHGQFFDLMKLFEVGGSPVNTRYLFLGDYVDRG
YFSIECVLYLWSLKIHHPRTFFLLRGNHECRHLTEYFTFRQECRIKYSEQIYDACMDTFD
CLPLAALLNQQFLCVHGGLSPEINSLDDIRRLDRFREPPAFGPMCDLLWSDPLEDYGSEK
TMEHFSHNTVRGCSYFYSYPAVCEFLQSNSLLSVIRAHEAQDSGYRMYRKSQTTGFPSLI
TIFSAPNYLDVYNNKAAVLKYENNIMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTE
MLVNILNICSDDELISDGEETLEGAASLRKEIIRNKIRAIGKMARVFAILREERESVLTL
KGLTPTGTLPLGVLSGGKQTIQLAIRGFSPPHKIRSFEEARGLDRINERMPPRRDKSFPE
GPVAVPANIVSSRSGSKGSSVTKGSSVTKGSSVTKGSSVTKGSSMTKGSTSKKSQ
NT seq 1608 nt   +upstreamnt  +downstreamnt
atgtcctcgaggactcgcaacaaactctctaccaccgagcgcgtcatcaaagctgttcct
tttcctccaactcggcggctcacaataaaagaagtatttgaagatggtaaacccagactt
gatgtcttgaaaagccacttggtgaaagaaggtagactagaggaggaagcagccttaaag
ataatcaatgatggaggtgccattctgaaaagtgaaaagactatgatagaattggaggca
cctatcacagtgtgtggtgatgttcatggacaattctttgacctgatgaaattgtttgaa
gttggaggatcacctgttaacacacgctacctcttcctgggagactatgtggatagaggc
tacttcagtatagagtgtgtgctgtacttatggagtttaaaaattcatcatcccagaacg
tttttcctgcttcgcggcaaccatgaatgcaggcatctcacagaatacttcactttcaga
caggaatgtcgaatcaaatattcagaacagatatatgatgcgtgcatggatacatttgat
tgtcttcctcttgctgctctcttaaaccagcagtttttgtgtgtacatggaggactgtct
ccagaaatcaattctttagatgacattaggagattagacaggtttagggaacctccagct
tttggaccaatgtgtgacctgctttggtctgatcccttggaggactatggcagtgagaag
accatggagcactttagccacaacactgtccgagggtgctcctacttttacagttatcct
gcagtttgtgaatttttgcaaagcaatagtttgttatcagtaatcagagcccatgaagct
caagattccgggtatcgaatgtataggaagagccagacaacaggctttccatcactcatt
acaattttctctgccccaaattacctagatgtctataacaacaaagctgctgtactgaaa
tatgagaataatatcatgaacatcagacagtttaactgctctccacacccctattggctt
ccaaactttatggatgtcttcacatggtctttgccttttgttggagagaaagtcaccgag
atgctggttaatattctcaacatatgctctgatgatgagttgatttcagatggtgaggag
acactggaaggagctgcatcacttcgtaaggagatcatcagaaataaaatcagggctatt
ggaaagatggcacgagtgtttgcaattcttcgagaagagagggaaagtgtgctgactctc
aaaggactgactcctacaggtacactacctctgggtgtcctctcaggaggaaagcaaacc
attcaattagcaatccgagggttttcaccccctcacaagatccgaagctttgaggaggct
cggggcctggaccggattaatgagcgcatgccccctcgaagagataaatcattccctgag
gggccagtagcagtgccggcaaatatagtgtcaagccgctcagggtccaagggcagctca
gtgaccaagggcagctcagtgaccaaaggcagctcagtgaccaagggcagctcagtgacc
aagggcagctcaatgaccaagggcagcacgtctaagaaaagccagtaa

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