Sarcophilus harrisii (Tasmanian devil): 100916611
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Entry
100916611 CDS
T02286
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04022
cGMP-PKG signaling pathway
shr04024
cAMP signaling pathway
shr04062
Chemokine signaling pathway
shr04071
Sphingolipid signaling pathway
shr04270
Vascular smooth muscle contraction
shr04350
TGF-beta signaling pathway
shr04360
Axon guidance
shr04510
Focal adhesion
shr04520
Adherens junction
shr04530
Tight junction
shr04611
Platelet activation
shr04670
Leukocyte transendothelial migration
shr04810
Regulation of actin cytoskeleton
shr04921
Oxytocin signaling pathway
shr05135
Yersinia infection
shr05163
Human cytomegalovirus infection
shr05200
Pathways in cancer
shr05205
Proteoglycans in cancer
shr05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
100916611 (ROCK1)
04071 Sphingolipid signaling pathway
100916611 (ROCK1)
04024 cAMP signaling pathway
100916611 (ROCK1)
04022 cGMP-PKG signaling pathway
100916611 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100916611 (ROCK1)
04520 Adherens junction
100916611 (ROCK1)
04530 Tight junction
100916611 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100916611 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100916611 (ROCK1)
04670 Leukocyte transendothelial migration
100916611 (ROCK1)
04062 Chemokine signaling pathway
100916611 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
100916611 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100916611 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
100916611 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100916611 (ROCK1)
05206 MicroRNAs in cancer
100916611 (ROCK1)
05205 Proteoglycans in cancer
100916611 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100916611 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100916611 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100916611 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
shr03036
]
100916611 (ROCK1)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
100916611 (ROCK1)
Protein kinases [BR:
shr01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
100916611 (ROCK1)
Chromosome and associated proteins [BR:
shr03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100916611 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
DUF1192
Cortex-I_coil
APH
Motif
Other DBs
NCBI-GeneID:
100916611
NCBI-ProteinID:
XP_031802411
UniProt:
G3WNF9
LinkDB
All DBs
Position
1:494138611..494266519
Genome browser
AA seq
1356 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSKYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLYYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLSVSSANPNDNRTTS
NIDKSLQESLQNTIYKLEEQLHNEIQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRKNLE
STVSQIEKEKMLLQHRVNEYQRKIEQENEKRRNVENEVSTLKDQLDDLKKVSQNSQLTNE
KMAQLQKQLKEANDLLRTESDTAARLRKSHTELSKSVSQLESLNRELQERNRILETTKSQ
VDKDYYQLQAALEAERRDRSHGSEMIGDLQARITSLQEEVKHLKQNLERVEGERKEAQDM
LNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEK
KLKEERAAREKAENRVVHIEKQCSMLDVDLKQSQQKLEHLAEHKERMEDEVKNLTLQLEQ
ESNKRLLIQNELKTQAFEKDNLKGLEKQMKQEINTLLEAKRLLEFELAQLTRQYCGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEDIEEKNRENLKKIQELQNEKETLAAQLDLVETK
AESEQLARRLLEEQYFELTQECKKAASRNKQEITDKDHTVNRLEEINSTLTKDIELLRKE
NEEFTEKMRKEQEDYKLKKEEEINNLKASFEKNINTERTLKTQAVNKLAEIMNRKDFKID
RKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNEMQAQLVEECTHRNELQM
QLASKESDIEQLRAKLLDLSDSTSVTSFPSADETDGNLPESRIEGWLSVPNRGNIKRYGW
KKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQI
LYANEGECRKDLEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPA
LECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPK
NPPSSFVRASPRTLSTRSSANQSFRKVVKNTSGKTS
NT seq
4071 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgagaaaatcgacaacctgctgcgggac
ccgaagtcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgcactaagaaaaaacaaaaatattgacaactttttaagcaaatataaa
gatacaataaataaaattagagatttgcgcatgaaagctgaagattatgaagtggtgaaa
gtgattggtagaggtgcatttggagaagtgcaattggtaaggcataaatctaccaggaag
gtatatgctatgaagctgctgagcaaatttgagatgattaagagatcagattctgctttc
ttctgggaagaacgggacattatggcttttgctaatagcccttgggtcgttcagctatat
tatgcattccaagatgatcggtatctctacatggtaatggaatatatgcctggtggggat
cttgttaatttaatgagcaactatgatgtgcctgaaaaatgggcccgtttttatactgcg
gaagtagttcttgctttggatgcaatccattcaatgggctttattcatagagatgtgaag
cctgataacatgctgctggataaatctggtcacttgaagctagctgattttggtacttgt
atgaagatgaataaagaaggtatggtacgatgtgatacagcagttggaacacctgactat
atttctcctgaagtattaaaatcccaaggtggtgatggctattatgggcgagaatgtgac
tggtggtctgttggtgtgtttttatatgaaatgcttgtaggtgatacaccattttatgca
gattcactggttggaacatatagcaaaattatgaaccataagaattctcttacctttcct
gatgataatgatatatcaaaggaagcaaaaaatcttatttgtgccttccttacagacagg
gaagtgagattaggacgaaatggtgtggaagaaatcaaacgacatctcttcttcaaaaat
gatcaatgggcatgggaaactcttcgagatactgttgcacctgttgtacctgatctcagt
agtgacattgatactagtaattttgatgacttagaagaagacaaaggagaagaagaaaca
tttcccattccaaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatatttatctgtatcttcagccaatcctaatgataatagaaccacctcc
aatatagataaaagcttgcaggaaagtttgcaaaatacaatctataagctggaagaacaa
ttgcataatgaaatacagctaaaagatgaaatggagcagaagtgcagaacttcaaacata
aaactagacaagataatgaaagaactggatgaagagggaaatcaaagaaaaaatttagaa
tccacagtgtctcagattgagaaagagaaaatgttgctgcagcacagagttaatgagtac
caaagaaaaatagaacaggagaatgagaagagaaggaatgttgaaaatgaagtttctaca
ttaaaagaccaattggatgacctgaagaaagttagtcagaattctcagcttacaaatgag
aaaatggcacaattacagaagcaactaaaagaagcgaatgacttactgaggacagaatca
gacacagcagcaagattaagaaagagccacacagaattaagcaaatcagtaagtcagtta
gagtccctaaacagagaattgcaagagcgaaacagaattttagagacaaccaaatcacaa
gtggacaaggattattaccagcttcaggctgcattagaagctgaaagaagagaccgaagt
catggatcggagatgataggagatcttcaagctcgaattacatctttacaagaagaagtg
aaacaccttaaacaaaatcttgaaagagtggaaggggaaagaaaagaagctcaagacatg
cttaatcactcagaaaaggagaagaataatttggaaatagatttaaactacaagctaaaa
tcattacaacaaagattagaacaggaagtaaatgagcataaagtgactaaagcccgtttg
actgacaaacatcaatctattgaagaagcaaagtcagttgcaatgtgtgaaatggaaaag
aaactgaaggaagagagagcagcccgagagaaagctgaaaatagagttgttcatattgaa
aagcagtgttctatgctagatgttgacttgaaacagtctcaacagaaactggaacattta
gcagaacataaagaaaggatggaagatgaagttaagaatctaacactgcagttggagcaa
gaatcaaataaacggttgctgatacagaatgaattaaaaactcaagcttttgagaaggat
aatttgaaagggttagaaaagcaaatgaaacaagaaatcaatacattattggaagcaaag
agattactggaatttgaactagcccagcttacaagacaatattgtggaaacgaaggacag
atgcgggaactacaggatcagcttgaagctgaacaatatttttcaacactttataaaact
caggtaaaggaacttaaagaggacattgaagaaaaaaatcgagaaaatctaaagaaaata
caagagcttcaaaatgaaaaagaaacacttgctgcacagttagacctggtagaaacaaaa
gctgaatcagagcagttggctcgacgtctactggaagaacaatattttgaattgactcaa
gagtgtaaaaaagcagcttcacgaaataaacaagaaattacagataaagatcacactgtc
aatcggctggaagaaataaacagtacattaaccaaagatattgaattattaagaaaggaa
aatgaagagtttactgaaaaaatgaggaaggaacaagaagattataaattgaagaaagaa
gaagagatcaataatcttaaagcttcttttgaaaagaatattaatactgaaagaactcta
aaaacgcaggctgttaacaaattggctgaaataatgaatcgtaaagattttaaaattgat
agaaagaaggctaatacacaggatttaagaaagaaggaaaaggaaaacaggaagttacaa
ctggaactcaaccaagaaagagagaaattcaatcaaatggtagtgaaacaccagaaagaa
ctcaatgaaatgcaagcgcaattggttgaagagtgcacacacaggaatgaacttcagatg
cagctggctagcaaagagagtgacatagagcagttgcgtgcaaaacttttggacctttca
gattctaccagtgttactagttttcctagtgccgatgaaactgatggaaaccttccagaa
tcaagaattgaaggttggctatcggttccaaacagaggaaatataaaacgatatggctgg
aagaaacagtatgtcgtagtaagcagcaaaaaaattttgttctacaatgatgaacaggat
aaggaacagtcaaatccatctatggtactagacatagacaaactattccatgttcgacct
gtaacccaaggtgatgtgtacagagcagaaaccgaagaaatccctaaaatattccagata
ttgtatgcaaatgaaggtgaatgtaggaaagatttggaaatggagccagtacaacaagct
gagaagaccaattttcagaatcacaaaggccatgagtttattcctacactctatcacttt
ccagccaactgtgaggcttgtgccaaacctctctggcatgtttttaagccaccccctgcc
ctcgaatgtcgaagatgccatgtcaagtgccatagagatcacttagacaaaaaagaagac
ttaatttctccatgcaaagtgagttatgatgtaacatcagcaagagatatgctgctgtta
gcatgttctcaggatgaacagaagaaatgggtaacccatttagtaaagaagatccctaag
aatccaccatccagttttgttcgtgcctcccctagaacactttctactagatctagtgca
aatcagtctttccggaaagttgtcaaaaatacatctgggaaaactagctaa
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