Sarcophilus harrisii (Tasmanian devil): 100916673
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Entry
100916673 CDS
T02286
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr01522
Endocrine resistance
shr04010
MAPK signaling pathway
shr04014
Ras signaling pathway
shr04015
Rap1 signaling pathway
shr04066
HIF-1 signaling pathway
shr04068
FoxO signaling pathway
shr04081
Hormone signaling
shr04114
Oocyte meiosis
shr04140
Autophagy - animal
shr04144
Endocytosis
shr04150
mTOR signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04152
AMPK signaling pathway
shr04211
Longevity regulating pathway
shr04213
Longevity regulating pathway - multiple species
shr04510
Focal adhesion
shr04520
Adherens junction
shr04550
Signaling pathways regulating pluripotency of stem cells
shr04730
Long-term depression
shr04913
Ovarian steroidogenesis
shr04914
Progesterone-mediated oocyte maturation
shr05200
Pathways in cancer
shr05202
Transcriptional misregulation in cancer
shr05205
Proteoglycans in cancer
shr05214
Glioma
shr05215
Prostate cancer
shr05218
Melanoma
shr05224
Breast cancer
shr05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100916673 (IGF1R)
04014 Ras signaling pathway
100916673 (IGF1R)
04015 Rap1 signaling pathway
100916673 (IGF1R)
04066 HIF-1 signaling pathway
100916673 (IGF1R)
04068 FoxO signaling pathway
100916673 (IGF1R)
04151 PI3K-Akt signaling pathway
100916673 (IGF1R)
04152 AMPK signaling pathway
100916673 (IGF1R)
04150 mTOR signaling pathway
100916673 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
100916673 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100916673 (IGF1R)
04140 Autophagy - animal
100916673 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
100916673 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100916673 (IGF1R)
04520 Adherens junction
100916673 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
100916673 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100916673 (IGF1R)
04914 Progesterone-mediated oocyte maturation
100916673 (IGF1R)
09156 Nervous system
04730 Long-term depression
100916673 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
100916673 (IGF1R)
04213 Longevity regulating pathway - multiple species
100916673 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100916673 (IGF1R)
05202 Transcriptional misregulation in cancer
100916673 (IGF1R)
05205 Proteoglycans in cancer
100916673 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100916673 (IGF1R)
05214 Glioma
100916673 (IGF1R)
05218 Melanoma
100916673 (IGF1R)
05215 Prostate cancer
100916673 (IGF1R)
05224 Breast cancer
100916673 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100916673 (IGF1R)
01522 Endocrine resistance
100916673 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100916673 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
shr04090
]
100916673 (IGF1R)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100916673 (IGF1R)
Protein kinases [BR:
shr01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100916673 (IGF1R)
CD molecules [BR:
shr04090
]
Proteins
100916673 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Adeno_E1A
Motif
Other DBs
NCBI-GeneID:
100916673
NCBI-ProteinID:
XP_031811379
LinkDB
All DBs
Position
2:532980243..533343758
Genome browser
AA seq
1364 aa
AA seq
DB search
MKSGAGRGSPTSLWGLLFLFSTLCLWPTNGEICGPNIDIRNEIQELKRLENCTVIEGYLR
ILLISKAEDYRNFRFPKLTVITDYLLLFRVAGLESLSDLFPNLTVIRGRNLFYNYALVIF
EMTNLKEIGLYNLRNITRGAIRIEKNSDLCYLSTVDWSLILDAVSNNYIVGNKSPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNHCQKMCPSSCGKRACTDQNQCCHPECLGSCS
APDNDTACVACRHYYYGGTCVPTCPPNTYKFEGWRCVDKDFCASVHSAEANEYEKFVIHN
DECMQECPSGFIRNGSQSMYCSPCEGPCPKVCEGEKKTKTIDSVTSAQMLQGCTVFKGNL
LINIRRGNNIASELENFMGLIETVTGYVKIRHSHALVSLSFLKNLRYILGEEQLEGNYSF
YVLDNQNLQQLWDWNLHNLTIKEGKMYFAFNPKLCVSEIYRMEEVSGTKGRQSKGDINTR
NNGERASCESDVLHFISNTTMKNRIKLTWQRYRPPDYRDLISFTVYFKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVKPGILLQGLKPWTQYAIYVKAVTLTMVENDHIRGAKSQ
IVYIRTKAAVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKVPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERRRRDVFQIANSTLPSRNRNTTMADHFTNVSDTEEIESEYPFFE
SRVDNKERTLISHLRPFTLYRIDIHSCNHEADTLGCSASNFVFARTMPAEGADNIPGPVQ
WEPRPDNTVYLKWAEPENPNGLILMYEIKYGQQVEDQRECVSRQEYRKFGGARLTRLNPG
NYSARVQATSLSGNGSWTDPVFFYVPAKPPDYENFLHLMIALPIAGLFILGGILIMWYVY
NKKRNSDRLGNGVLYASVNPEYFSAADVYVPDEWEVPREKITMSRELGQGSFGMVYEGVA
KGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI
MELMTRGDLKSYLRSLRPETENNPCQMLPTLKKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDELDPGFKEVSFFYSEENKPPDTEELDLETENMESIPLDPSSTLQPADKLS
GHKAENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC
NT seq
4095 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggcgccggaagagggtccccgacctcactttgggggcttctgtttctcttt
tctacactttgcctttggccaacaaatggagaaatttgtgggccaaacattgacattcgc
aatgaaatccaggagttgaagcgactagaaaactgcacagtgattgagggctacctccga
attctactgatctctaaggcagaagactaccggaacttccgattcccaaagctcacagtc
atcactgactacttgctgctttttcgtgtggcaggcttggagagccttagtgacctcttc
cctaaccttacggtcatccgagggagaaaccttttttataactatgctctggtgatcttt
gagatgacaaatctcaaagaaatcgggctgtataaccttaggaatatcactcggggggcc
atcaggattgagaagaattcagacctctgttacctctccactgtagactggtctttgatt
ctggatgctgtatctaacaactatattgtgggaaataaatctcccaaggagtgtggggac
ctttgtccagggacaatggaagagaagccattgtgtgaaaagacaaccattaataatgag
tacaactaccgctgctggaccacaaaccactgtcagaaaatgtgtcctagctcatgtgga
aaacgagcctgcacagaccagaatcagtgctgtcacccagagtgcttaggaagctgtagt
gcaccagacaacgacacagcctgtgtggcttgtcgccattactactatgggggcacttgt
gtgcccacctgtcctcccaacacttacaagtttgagggttggcgttgcgttgacaaagat
ttctgtgccagtgtccacagcgctgaagccaatgaatatgaaaagtttgtgatccacaat
gatgagtgcatgcaggagtgtccctctgggttcatacggaatgggagccaaagtatgtac
tgcagtccctgtgaaggtccttgccctaaagtctgtgaaggagagaagaagacaaagaca
attgattctgtaacttcagcacaaatgctgcagggatgcactgtcttcaaaggcaatttg
cttattaatatccggcgaggcaataacatagcctctgagctggaaaacttcatgggcctt
attgagactgttacgggatatgtgaagattcgccattcacatgccttagtctctctgtct
ttcttgaaaaacctgagatatattttaggagaagaacagctagaagggaattattctttc
tacgtccttgataaccagaatttacagcagctctgggactggaatctccataatctgaca
atcaaagaagggaaaatgtattttgcttttaatcccaaattgtgtgtttctgaaatttat
cgaatggaggaagtgtcaggaactaaaggtcgccagagcaaaggagacataaacactagg
aacaatggagaaagagcctcttgtgaaagtgatgttttgcatttcatttccaacactaca
atgaagaaccggattaaactaacatggcaacgatatcgtcctcctgattatagagacctt
attagctttactgtttacttcaaagaggcaccattcaagaatgtcactgagtatgacggg
caagatgcatgtggctctaacagttggaacatggttgatgtggaccttcctccaaataag
gatgtcaaacctggaattttactgcaaggactgaaaccttggactcagtatgccatctac
gtcaaagcagttactctcacaatggtggagaatgaccacattcggggagctaaaagtcaa
attgtgtatattcgtaccaaagctgcagttccttctattcccttggatgttatttcagca
tctaactcatcctcccagttaattgtgaagtggaatcctccttccctcccaaatggtaac
ttatcttactacatagtaagatggcagaggcaacctcaagatagttacctctaccgacac
aattactgctccaaagacaaagttccaattagaaagtatgccgatggcaccattgatgtt
gaagaggttactgaaaaccccaaaactgaagtctgtggtggggagaaaggaccttgctgt
gcttgtcctaagactgaggctgagaaacaagcagagaaagaagaagctgaatacagaaaa
gtttttgagaattttctgcacaactccatctttgtacccagacctgaaaggaggcgtaga
gatgtctttcaaattgcgaattctacattgcccagtcggaacaggaacactacaatggcg
gatcacttcaccaatgtgtcagacacagaagaaattgaatctgaatacccgttctttgag
agtagagtggataataaagaaaggactttaatttctcatcttaggccttttactttgtat
cgaattgatattcatagctgcaaccatgaagctgatactcttggctgtagtgcttcgaac
tttgtctttgccaggaccatgccagcagaaggagcagataatattcctgggccagtgcag
tgggagccaagaccagataatactgtctacttgaagtgggcagaacctgaaaatcccaat
ggattgatattaatgtatgaaataaagtatggtcaacaagtagaggatcagcgggaatgt
gtttccagacaggaatacaggaaatttggaggggccaggcttacacggctgaaccctggg
aactattcagcccgtgttcaggccacctctctttctgggaatggatcatggactgaccct
gtattcttttatgtcccagccaaaccaccagattatgaaaacttccttcacttaatgatc
gctctacccatcgcaggattatttatacttggtggaatactgataatgtggtatgtctac
aataaaaaaagaaacagtgacagattagggaatggagttctatatgcatctgtcaatcca
gagtacttcagtgctgcagatgtgtatgttccagatgagtgggaggtacctcgagagaag
atcaccatgagtcgagaacttgggcagggttcatttgggatggtatatgagggagttgca
aagggtgtggtgaaagatgaacctgaaaccagagtggccatcaaaacagtcaatgaagca
gcaagcatgcgagaaagaattgaatttctcaatgaagcttcagtaatgaaagaattcaat
tgtcatcacgtggtgcggttgcttggagtagtgtcccagggccaaccaactttagtcatc
atggaattgatgacacgaggggatctcaaaagttacctcagatctctgaggccagaaaca
gagaataatccatgccagatgcttccaactttaaagaagatgattcagatggctggagag
attgctgatggtatggcatatctcaatgccaacaagtttgtccacagggatctcgctgca
aggaattgcatggttgccgaagatttcaccgtcaaaattggagattttggtatgacaaga
gatatctatgagacagattactaccgaaaaggaggtaaaggattattacctgttcgttgg
atgtctccagagtcacttaaggatggagtcttcacaacacattctgatgtttggtccttt
ggtgttgtcctctgggagattgcaacattagcagagcagccctatcagggcatgtctaat
gaacaagttctccggtttgttatggagggtggccttctagagaaaccagacaactgcccc
gatatgctgtttgaattgatgcgtatgtgctggcagtacaatcccaaaatgagaccttct
tttctggagatcatcggcagcatcaaagatgaactggaccccggcttcaaggaggtctcc
ttcttctacagtgaagaaaataagcccccagacacagaagagctggacttagagactgag
aacatggagagtatccccttagacccttcctccaccctccagccggctgacaaactctca
ggacacaaagccgagaacgggcctggtgtggtggtcctcagggccagctttgacgaaagg
cagccttacgcgcacatgaatggaggacgcaagaacgaaagggccttacctttgccccag
tcttcggcctgctga
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integrated database retrieval system
