Sarcophilus harrisii (Tasmanian devil): 100917433
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Entry
100917433 CDS
T02286
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04010
MAPK signaling pathway
shr04020
Calcium signaling pathway
shr04022
cGMP-PKG signaling pathway
shr04024
cAMP signaling pathway
shr04260
Cardiac muscle contraction
shr04261
Adrenergic signaling in cardiomyocytes
shr04270
Vascular smooth muscle contraction
shr04723
Retrograde endocannabinoid signaling
shr04725
Cholinergic synapse
shr04726
Serotonergic synapse
shr04727
GABAergic synapse
shr04911
Insulin secretion
shr04912
GnRH signaling pathway
shr04921
Oxytocin signaling pathway
shr04924
Renin secretion
shr04925
Aldosterone synthesis and secretion
shr04927
Cortisol synthesis and secretion
shr04929
GnRH secretion
shr04934
Cushing syndrome
shr04935
Growth hormone synthesis, secretion and action
shr05010
Alzheimer disease
shr05020
Prion disease
shr05022
Pathways of neurodegeneration - multiple diseases
shr05207
Chemical carcinogenesis - receptor activation
shr05410
Hypertrophic cardiomyopathy
shr05412
Arrhythmogenic right ventricular cardiomyopathy
shr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100917433 (CACNA1S)
04020 Calcium signaling pathway
100917433 (CACNA1S)
04024 cAMP signaling pathway
100917433 (CACNA1S)
04022 cGMP-PKG signaling pathway
100917433 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100917433 (CACNA1S)
04929 GnRH secretion
100917433 (CACNA1S)
04912 GnRH signaling pathway
100917433 (CACNA1S)
04921 Oxytocin signaling pathway
100917433 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
100917433 (CACNA1S)
04924 Renin secretion
100917433 (CACNA1S)
04925 Aldosterone synthesis and secretion
100917433 (CACNA1S)
04927 Cortisol synthesis and secretion
100917433 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
100917433 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
100917433 (CACNA1S)
04270 Vascular smooth muscle contraction
100917433 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
100917433 (CACNA1S)
04725 Cholinergic synapse
100917433 (CACNA1S)
04726 Serotonergic synapse
100917433 (CACNA1S)
04723 Retrograde endocannabinoid signaling
100917433 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100917433 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
100917433 (CACNA1S)
05020 Prion disease
100917433 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
100917433 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100917433 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
100917433 (CACNA1S)
05414 Dilated cardiomyopathy
100917433 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100917433 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
shr04040
]
100917433 (CACNA1S)
Ion channels [BR:
shr04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100917433 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
100917433
NCBI-ProteinID:
XP_031792976
Ensembl:
ENSSHAG00000001786
LinkDB
All DBs
Position
4:complement(93902407..94001766)
Genome browser
AA seq
1878 aa
AA seq
DB search
MEPSSPQDENQKKKQPKKPLPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVSTVILEEINLIQSNSTPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIIKAMIPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIIATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNNGITHFDNFGFSMLTVYQCMTMEGWTDVLYW
VNDAIGNEWPWIYFVSLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLKGYMNWITQAEVMDIDDIREGKLSLDEGGSDTESLYEIEGLNKFIQFLRHWRQWNRI
FRRKCQEVVKSKVFYWLVILVVALNTLSIASEHHLQPLWLTHLQDVANRVLLALFTIEML
MKMYGLGLRQYFMSVFNRFDCFVVCSGIIEIILVESGIMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSVRSIASLLLLLFLFIIIFALLGMQLFGGKYDFEDTEVRRSNFDTF
PQALISVFQILTGEDWNSIMYNGIMAYGGPSYPGVLVCIYFIILFICGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKLILAKKLEQKAKGEGIPTTAKL
KVDEFESNVNEVKDPYPSADFPGDDEEEEPEIPLSPRPRPLAELQLKEKAVPMPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSISLAAEDPIEAESFRNKILSKFDIAFT
SVFTVEIVLKMTAYGAFLHKGSFLRNYFNILDLLVVAVSLISMGIESSTISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGMFYSCNDL
SKMTEAECKGYYYVYKDGDPNQMQVYPREWLHNDFNFDNVLSAMLALFTVSTFEGWPQLL
YKAIDTHTEDMGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFIIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYKVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMILKLMAFKAKGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCANTDPDESARISSAFFRLFRVMRLIKLLSRGEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLASSYGKLCDPKSDAPVGEEYTCGTGFAYFYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKKIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLISMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
SIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIYRRTGGLFGQVDTFLERTDSLPP
NVASQRPLQFTEMEMEDMDSPVFLDDFPPEPPANPLARTHANTNASNANANNANSCVSSS
IHHENELPALSSPKKDALYHPHSAPAEHQDDFYPEKHKVRMTRRKITSLGACSKAQAPPC
PDQAHRKEDDVSRGRESPPPESPCTETTGGGQGADPEAPAPSTPATARLIRKALVQGGLG
TLAGDTGFVVATGRALADACQMEPEEVEEAANELLKGQECPKDRNRSPSSLESQAIGPAP
GSYDGSWGSREALITTQL
NT seq
5637 nt
NT seq
+upstream
nt +downstream
nt
atggagccctcctcaccccaggatgagaaccagaagaagaagcaacccaagaagccactt
cctgagattctgccccgaccaccccgggcactgttctgtctcaccctccagaaccccctg
aggaaggcctgcattagcattgtagaatggaaaccctttgagacaatcatcttactcacc
atctttgccaactgtgtggctctggcggtatacttgcccatgcctgaggatgacaacaat
tccctcaaccttggcctggagaagttggagtacttcttcctcattgtcttttcaattgaa
gccgccatgaagatcatcgcttatggtttcctcttccatcaagatgcctacctgcgcagt
ggctggaatgtgctagattttatcattgtcttccttggggtttccaccgtgattctggaa
gagatcaacttgatccaaagcaattcgacccccatgagcagcaaaggagctggtttggat
gtcaaggccctacgagccttccgagtcctcagacccctccgattggtgtcaggggttcca
agcttgcaggttgttctcaattccatcatcaaggccatgattcctttgttccacatcgcc
ctgctcgtcctcttcatggtcatcatctacgccatcattggactggaactcttcaaggga
aaaatgcacaagacctgctacttcattggaacagacatcattgccacagtggagaatgag
aagccatccccttgtgctaggacaggctccggacgcccatgtaccatcaatggcagcgag
tgccgaggtggctggccgggtcccaataatggcatcacccattttgataattttggcttt
tccatgcttaccgtgtaccagtgcatgaccatggagggctggactgatgtcctctactgg
gtcaatgatgccattggaaacgagtggccctggatttattttgtcagcctcattctcctg
ggatccttcttcatccttaacctcgttctgggtgtcctgagtggtgagttcaccaaagaa
cgggaaaaggccaagtctcggggaacctttcagaagcttagggaaaagcagcaattggag
gaagaccttaagggttatatgaactggatcactcaagcagaagtcatggatattgatgat
ataagagaaggaaagctgtcattggatgaaggtggctcagatacagaaagcctctacgaa
atagaaggcttgaacaaatttatccaatttctccggcattggagacagtggaatcgcatc
ttccgccggaaatgtcaagaagtggtgaaatccaaggtcttttattggctggtgatcctg
gtcgtggccctcaacaccctgtccattgcctcagaacaccacctccagcctctgtggttg
acccatttgcaagatgtggctaatcgtgtgcttctggctctcttcaccatcgagatgctg
atgaagatgtatggactggggcttcgacagtatttcatgtctgtcttcaatcgctttgac
tgttttgtggtgtgcagtggaatcatagagatcattctggtggaatctgggatcatgact
cccctcggcatctctgtactccgatgtatccgccttctgagaatctttaagatcaccaag
tactggacgtctctgagcaacctggtggcctctctgctcaattctgtccgctccattgcc
tccctgctccttctgctcttcctctttatcatcatctttgccctcttgggaatgcagctt
tttgggggcaagtatgactttgaggacacggaggtgaggcgcagcaacttcgataccttc
ccccaggctctcatcagcgtcttccagatccttacaggtgaagattggaactcgattatg
tacaatggcattatggcatatggtggaccctcttatccaggcgtgctggtctgcatctat
ttcattatcctcttcatctgtggcaactatatcctgctcaatgtctttttggccattgct
gtggacaacctggccgaggctgagagtttaacctctgcccagaaagccaaggctgaagag
aagaagcgcaggaaaatgtccaagggtctcccagacaaatctgaggaagagaagttgatt
ctggccaagaagttagaacagaaagccaagggagaaggcatccctaccacagccaagctg
aaagtggatgagtttgaatccaatgtcaatgaagtgaaggatccatacccttcagcagat
tttccaggagacgatgaggaagaggaaccagagatcccactgagccctcggcctcgcccc
ttggcagagctacagctgaaagaaaaagcagtacccatgcctgaagccagttcatttttt
atcttcagccctactaataagatcagagtactgtgtcatcgcatagtcaatgctacctgg
tttaccaacttcatcctgctcttcattctgctcagcagtatttccctggcagcagaggat
cccattgaggcagaatccttcaggaataagatccttagcaaatttgacattgccttcact
tctgtcttcactgtcgaaattgtgctcaagatgacagcttatggtgccttcctacacaag
ggctccttcttacgcaactacttcaatatcctggacctgctggtcgtggccgtatccctc
atctccatgggcattgaatccagtaccatctctgtggtgaagatcctcagggtactgagg
gtactccgacccctccgagccatcaacagagccaaaggattgaagcatgtagttcagtgt
gtatttgtggccatccggaccattggcaacatcgttttagtaaccaccctcctgcagttc
atgtttgcctgcattggagtccagctcttcaaggggatgttctacagctgcaatgactta
tctaagatgactgaagctgagtgcaaggggtattactatgtgtacaaagatggagacccg
aaccagatgcaagtatatccccgagagtggctacacaatgacttcaacttcgacaatgtg
ctgtccgccatgttggcgctcttcactgtctcaacctttgagggatggccccagcttctc
tacaaagctattgacacacatactgaggatatgggtcccatttacaacaaccgtgtagag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaatatcttt
gtgggctttatcatagtcaccttccaggagcagggtgagaccgaatacaagaattgtgag
ctcgacaagaaccagcgccagtgtgtgcagtatgccctgaaagcccgcccactgagatgc
tacatccctaagaatccctatcagtacaaagtgtggtacgtcgtcacctcctcctacttt
gagtacctgatgttcgccctcatcatgctcaacaccatctgcctggggatgcagcattac
aaccagtcagaagaaatgaaccacatctcggatatcctcaatgtggccttcacaatcatc
tttaccttggagatgattctcaagctcatggccttcaaagccaagggctactttggggac
ccctggaatgtgtttgacttcctgattgtcatcggcagcatcattgacgtcatccttagc
gagattgatactttcctggcttccagtgggggactgtactgcctgggaggaggctgtgcc
aacactgatcctgatgagagcgcccgcatatccagtgcctttttccgcctgttccgagtc
atgaggctgataaaactattgagcaggggtgagggtgtccgaacactgctctggaccttc
atcaagtccttccaggctttgccatatgtggccctgctaattgtgatgctcttcttcatc
tatgccgtcatcgggatgcagatgtttgggaaaattgctatggtggatgggacccaaatc
aatcggaataataacttccagacgttcccacaagctgtgctgctgctcttcaggtgtgcg
acaggagaggcatggcaggaaatcttgctggcctccagctatggaaaactctgtgacccc
aagtctgatgctcctgttggggaggagtatacctgtggtacaggctttgcctatttctac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctgtttgtggctgtcatt
atggacaactttgactacctcacccgagactggtccatcctgggcccacatcacctggat
gagttcaagaagatctgggctgaatatgaccctgaagctaagggcagaatcaagcatctg
gatgtcgtgaccctgttgagaagaatccaaccccctctgggctttgggaagttttgcccc
caccgtgtggcatgtaagcgattgataagcatgaacatgcccctgaacagtgatgggacc
gtcaccttcaatgctactctctttgctctggttcgaacagctctcaagatcaaaacagaa
ggtaactttgaacaggccaatgaggagctacgagccatcatcaagaagatttggaagaga
actagtatgaagcttctcgatcaagtcattccccccattggagatgatgaagtgaccgta
ggaaaattctatgctaccttcctcatccaagagcatttccggaagtttatgaagcgccag
gaggagtattatggatatcggcccaaaaaagacactgtgcagatccaggctggtcttcgg
agtattgaggaggaagcggctcctgagatccaccgagccatctctggagatctgacagcc
gaggaagagctggagagggccatggtggaggcggccatggaggaagggatctaccggagg
acgggcggcctttttggccaggtggacaccttcctggagaggaccgactcgctgcccccc
aacgtggccagccagaggcccctgcagttcaccgagatggagatggaggacatggactca
cccgtctttttagatgacttccccccagaacctcctgccaaccccctggccaggactcac
gccaacacaaatgccagcaatgccaacgccaacaacgccaacagctgtgtatcctccagt
atccatcatgagaatgagcttccagcattatcttccccgaagaaggatgccctttatcac
cctcactctgctccagcagaacatcaagatgatttttatccggagaaacataaggttaga
atgacccggaggaagataaccagcctgggggcatgctccaaggcccaagctcccccttgc
cctgaccaggctcacaggaaggaggatgatgtttccagggggagagagagccccccgcca
gagtccccgtgcacagagacaacaggtggaggtcagggggcagacccagaagctcctgca
ccttctacacctgctactgcccgattgatccggaaggctctggttcaaggtggcctgggc
accctggctggcgatacgggctttgtggtggcaaccggacgggcactggccgacgcctgc
cagatggaaccagaggaagtggaggaggcagcaaatgagctgctgaaaggacaggagtgt
ccaaaagacaggaacaggtccccttcatccctggagtctcaagccatagggcctgcgcca
ggcagctatgatgggtcgtggggctcccgagaggccctcatcaccacccagctgtga
DBGET
integrated database retrieval system
