Sarcophilus harrisii (Tasmanian devil): 100919404
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Entry
100919404 CDS
T02286
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00230
Purine metabolism
shr01100
Metabolic pathways
shr04934
Cushing syndrome
shr05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100919404 (PDE11A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100919404 (PDE11A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100919404 (PDE11A)
Enzymes [BR:
shr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100919404 (PDE11A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
100919404 (PDE11A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_3
HD-CE
HD
Motif
Other DBs
NCBI-GeneID:
100919404
NCBI-ProteinID:
XP_031816272
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All DBs
Position
3:394389187..394841582
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AA seq
930 aa
AA seq
DB search
MSAPCLDFGEVESFLDRHPELFEDYLMRKGRQELVQKWLKKNEQNQRVSAPGHFPSEART
PDSSAAAGSCSVTVQQGSSNSQPIPGVGDGGNVPMSPNWAGSRGDGGLQRRASQKELRKS
FARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQ
YPPTAIDYKCHLKQHNERQFFLELVKEISNDLDLTSLSYKILIFVCLMVDADRCSLFLVE
GTASGKKSLVSKFFDVHAGTPFLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYK
DRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKTPEGVPFTDDDEKVMQMYLP
FCGIAIANAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCS
VLLLEDIESPVVKFTKSFELMSPKCSADAENSFKDSMEKSSYSDWLINNSIAELVASTGL
PVNITDAYQDPRLDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQ
RLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVS
ELAIGDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYH
NWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALA
QLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDIILYFERR
TEFFELVSKGDYNWNVKTQRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDR
ERAELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSIAVNRSK
WEELHQKMLLSQIPSPPSSSSLIVSVEDIS
NT seq
2793 nt
NT seq
+upstream
nt +downstream
nt
atgtcagctccttgcctggactttggggaggtggaaagtttcctggacaggcacccagag
ctctttgaagactatttgatgaggaaggggaggcaggagctggtgcagaagtggttgaag
aagaatgagcaaaaccagagggtctcagccccaggacactttccttcagaggccaggacc
ccagatagtagtgctgctgctggtagttgtagtgtcactgtccagcaggggtcttcgaac
agtcagcccattccaggagtgggagatggtggcaatgtccccatgagtcccaactgggcc
ggaagccgtggtgatgggggcctacagcggagggcttctcagaaagaattgagaaagagc
tttgccaggtccaaagccatccacgtgaataggacttatgatgagcaagtcacatccagg
gcccaagaaccactgagtagtgtgaggcggagggccctgctccgaaaagctagttctctg
cctccaactactgcccacattctcagtgccctactggagtctcgggtcaacttaccccaa
tatcccccaacagccattgactacaagtgccacctcaagcagcacaatgaacgacaattc
ttcctggagctggtcaaggagatttccaatgacctggatctcaccagtctcagctacaaa
atcctcatctttgtctgccttatggtggatgccgaccgatgctccctgttcttggtggag
gggacagcctcaggcaagaaaagcctggtctctaaattctttgatgtacatgctgggacc
ccatttcttccttgtagcagcactgagaactctaatgaagtgcaggtgccttggggaaaa
ggcatcattggctatgttggggagcatggggagacagtcaacattcctgatgcttacaag
gaccgaagattcaatgatgaaatcgacaagctgaccggatacaagacaaagtctctgttg
tgtatgccaatcagaaacagcgatggggagatcattggtgttgcacaagcaataaacaaa
actcctgaaggtgttcccttcactgatgatgatgaaaaagttatgcagatgtatctccca
ttttgtgggattgccatagctaatgctcaactgtttgctgcctcaaggaaggagtatgac
agaagcagggctctgcttgaggtggttaatgacctttttgaagaacaaactgacctggag
aaaattgttaagaaaatcatgcaccgggcccagacgttgttaaaatgtgaacgctgttca
gttttgctcctagaggacattgaatcaccagtggtaaagtttaccaaatcctttgaattg
atgtctcccaagtgcagtgctgatgcagagaacagtttcaaagacagcatggagaaatcc
tcctattcagactggctcatcaataatagcattgctgagctggtagcttccaccggcctt
ccagtgaacattactgatgcttatcaagatcctcgcttggatgcagaagctgatcagata
tctggttttcatataagatctgtgctctgtgtccctatttggaacagcaatcaccaaata
attggagttgctcaagtcttaaatagactggatgggaaaccttttgatgatgctgatcaa
cgactttttgaggcctttgtcattttttgtggccttgggatcaacaacacaataatgtat
gatcaagtaaagaagtcctgggccaagcaatctgttgctcttgatgtgctgtcttatcat
gcaacatgttcaaaagccgaagtggacaaatttaaggcagccaacatccctctggtctca
gagcttgccattggtgacatacattttgatgacttttcccttgacgttgatgccatgatc
actgcagctctgcggatgttcatggagctggggatggtgcagaaatttaaaattgactat
gagacactatgtaggtggcttttgacagtaagaaagaattatcgaatggtactgtatcac
aactggagacatgctttcaatgtgtgccagctgatgtttgcaatgctaactacggctggg
tttcaggagattttgactgaggtggaaattttagccgtgattgtgggctgcctatgtcat
gacctcgaccacaggggaaccaacaatgccttccaagctaagagtggatctgctttggcc
cagctttatggaacttctgctaccttggagcaccatcactttaaccatgctgtgatgatt
ctacaaagtgagggtcacaacatctttgctaatttatcttccaaggaatacagtgatctc
atgcagcttttgaagcagtccatactagcaacagacataattctatattttgagaggaga
actgaattctttgaacttgtcagtaaaggggattacaactggaatgtcaaaacccagcgt
gatatatttcgatcaatgctaatgacagcctgtgaccttggagctgtgaccaaaccgtgg
gagatctcaagacaggtggctgaactggtaaccagtgagttctttgaacaaggagacaga
gaaagagctgaactcaaactcaccccttcggctatttttgatcgaaaccgaaaagatgaa
ctgcctcggttacaattggaatggattgatagcatctgcatgcctctgtatcaggcctta
gtaaaagtaaatgtgaaattgaagcccatgttggattctattgctgtgaatagaagtaaa
tgggaagagctgcaccagaaaatgttgctttctcagataccttctccaccttcctcttcc
agcctcattgtgtcagtggaagatatcagttaa
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