Sarcophilus harrisii (Tasmanian devil): 100920847
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Entry
100920847 CDS
T02286
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00760
Nicotinate and nicotinamide metabolism
shr01100
Metabolic pathways
shr04068
FoxO signaling pathway
shr04148
Efferocytosis
shr04152
AMPK signaling pathway
shr04211
Longevity regulating pathway
shr04213
Longevity regulating pathway - multiple species
shr04218
Cellular senescence
shr04310
Wnt signaling pathway
shr04922
Glucagon signaling pathway
shr04936
Alcoholic liver disease
shr05031
Amphetamine addiction
shr05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
100920847 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100920847 (SIRT1)
04068 FoxO signaling pathway
100920847 (SIRT1)
04152 AMPK signaling pathway
100920847 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100920847 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
100920847 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100920847 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
100920847 (SIRT1)
04213 Longevity regulating pathway - multiple species
100920847 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100920847 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
100920847 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100920847 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
shr03036
]
100920847 (SIRT1)
03029 Mitochondrial biogenesis [BR:
shr03029
]
100920847 (SIRT1)
Enzymes [BR:
shr01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
100920847 (SIRT1)
Chromosome and associated proteins [BR:
shr03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
100920847 (SIRT1)
Mitochondrial biogenesis [BR:
shr03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
100920847 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
100920847
NCBI-ProteinID:
XP_031812748
Ensembl:
ENSSHAG00000012695
UniProt:
G3WHH3
LinkDB
All DBs
Position
2:complement(634700250..634731455)
Genome browser
AA seq
719 aa
AA seq
DB search
MADEAALALEPGAGGGGPAEPGGEPLSKRQRRDGPGPCPGAERAGGAGSPGPEAAAALLG
EASDAVAPGGDNGPGPRDLRGLPREPPPPDDDDDDEDDDEEEEEEEGGEDEDEAAAAIGY
RENLFSDEILANGFHSCDSDEDDRASHASSSDWTPRPRTGPYTFVQQHLMIGTDPRTILK
DLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAG
VSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQP
SLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDSEAV
RDDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSL
KVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCQRLGGEYSRLCPN
PAKLSEITDKPPRTQKDFSAHWLALPPTPLNVSEDSSSPGRTSPPHSWAAERKPGDSDEG
ATSRGGCKAERPAPEGRAPSGHSASIMEQLEDPGAHSGENREKNERTSVMETLRKCWPNR
LAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCHSPSLEE
PIEDESEMEEFYNGLEDDADVAERGGPGCVCDRDGQRAVNEAASAKDEMAEVDHASNRS
NT seq
2160 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgccctggagcccggcgcgggcggcggaggtcccgcggag
cccggcggggagccgctcagcaagcggcagcgcagggacggcccgggcccctgcccgggg
gcggagcgggctggcggggcggggagcccgggcccggaggcggcggccgccttgctcggg
gaggcctcggacgcggtcgcccccggcggggacaatgggccgggcccgcgggacctgcgg
ggcctgccccgggagccgccgccgccggacgacgacgacgacgacgaggacgacgacgag
gaggaggaggaggaagaggggggcgaggacgaggacgaggcggcggcggcgattggctac
cgagaaaatctcttcagtgatgaaattcttgccaatggttttcattcctgtgacagtgac
gaggatgaccgagcctctcatgcaagctccagtgactggactcccagacctcgaacaggt
ccttacacttttgtgcagcagcatctcatgattggcacagaccctcggacgatcctaaag
gatctgttgccagaaacaatccccccgcctgaattagatgatatgacactctggcagatt
gttataaacatcctttcagaaccaccaaaaaggaaaaagagaaaagatattaatacaatt
gaggatgctgtgaaattattgcaggagtgcaaaaaaatcatcgttctgactggagctggg
gtatccgtttcctgtggaatacccgacttcagatcaagagatggtatttatgcacgcctg
gcagtagatttccctgacctccctgatcctcaagcaatgtttgatatcgaatatttcaga
aaggatccaagaccatttttcaaatttgcaaaggaaatttatcctgggcagttccaacca
tctctctgccataaatttatagccttgtcggataaggaaggaaaactgcttcgaaactac
acccagaacatagacacactggaacaagttgcggggattcagaggattatacagtgtcat
ggttcctttgcaacagcttcttgcttgatttgtaaatataaagtggattctgaagccgtg
cgtgatgatatttttaatcaggtggttcctcgatgtcccaggtgcccagctgatgagcca
cttgccatcatgaagccagagattgtattcttcggtgaaaacttaccagagcagtttcat
agagccatgaaatatgacaaagatgaagttgatctcctaattgttattgggtcttccctg
aaagtaagaccagtagcgctgattccgagttccataccccatgaagtgcctcagatcctg
atcaacagggaacctctgcctcacctgcactttgacgtcgagctcctgggcgactgtgac
gtcatcatcaatgagctctgccagaggctggggggggaatacagccgcctgtgccccaac
ccagccaagctctccgagatcacagacaagcctccacgcacccagaaagactttagtgcc
cactggctggcgctgccccccacgccgctcaatgtttccgaagactctagttcccccggc
agaacttccccaccacactcttgggcagctgagaggaaacctggggattccgatgagggg
gccacgtcacgggggggctgcaaggcagagaggccggcgccagaagggcgagcgccttcg
ggacactctgccagcattatggaacagctggaggatcctggagcccacagtggggagaac
agagagaaaaacgaacgaacttccgttatggaaacactgaggaaatgctggcccaacaga
ctggccaaagagcagatcagtaagcggcttgatggtaaccagtacctctttttaccaccc
aatcgttacatttttcatggcgccgaggtctactcagactctgaagacgatgtcctgtcc
tccagttcttgtggcagtaatagtgacagtggaacctgccacagcccgagcctagaagaa
cctatcgaggacgagagcgagatggaagaattctataacggcttggaggacgacgccgac
gtggccgagcgaggcgggcccgggtgtgtgtgtgaccgagacggccagcgggctgttaat
gaggctgcgtccgccaaggacgagatggccgaagtcgaccatgcatcaaaccgatcataa
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