Sarcophilus harrisii (Tasmanian devil): 100921140
Help
Entry
100921140 CDS
T02286
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00220
Arginine biosynthesis
shr00330
Arginine and proline metabolism
shr01100
Metabolic pathways
shr04020
Calcium signaling pathway
shr04081
Hormone signaling
shr04145
Phagosome
shr04371
Apelin signaling pathway
shr04713
Circadian entrainment
shr04730
Long-term depression
shr04926
Relaxin signaling pathway
shr04970
Salivary secretion
shr05010
Alzheimer disease
shr05014
Amyotrophic lateral sclerosis
shr05022
Pathways of neurodegeneration - multiple diseases
shr05410
Hypertrophic cardiomyopathy
shr05412
Arrhythmogenic right ventricular cardiomyopathy
shr05414
Dilated cardiomyopathy
shr05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100921140 (NOS1)
00330 Arginine and proline metabolism
100921140 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
100921140 (NOS1)
04020 Calcium signaling pathway
100921140 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
100921140 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
100921140 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
100921140 (NOS1)
09154 Digestive system
04970 Salivary secretion
100921140 (NOS1)
09156 Nervous system
04730 Long-term depression
100921140 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
100921140 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100921140 (NOS1)
05014 Amyotrophic lateral sclerosis
100921140 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
100921140 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100921140 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
100921140 (NOS1)
05414 Dilated cardiomyopathy
100921140 (NOS1)
05416 Viral myocarditis
100921140 (NOS1)
Enzymes [BR:
shr01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100921140 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Transglut_core2
Flavodoxin_1
YccV-like
NAD_binding_1
PDZ
PDZ_6
EF-hand_7
EF-hand_1
EF-hand_6
EF-hand_5
PDZ_2
EF-hand_8
Motif
Other DBs
NCBI-GeneID:
100921140
NCBI-ProteinID:
XP_031804524
LinkDB
All DBs
Position
1:complement(694885318..695301175)
Genome browser
AA seq
2126 aa
AA seq
DB search
MEDHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGRPLVDMSYDGALEVLRSIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTRPLGPATKTVDLSHQAVPSKDQPPGLDSVATLRNVPQRPRENGQEDNPLAQANGMVP
DPTKKSASSGLHGGGESNDLLREIQPVLNLLTSGKKEINGGQSHKVETKDAEVQADRDLE
GKSHKLLPLGMENDRVFNDLWGKNNMPVVLNNPYSEKEQPPTSGRQSPTKNGSPTKCPRF
LKVKNWETDVVLNDTLHLKSTLNTACTGQICMGSIMFPSQHIRKPEDVRTKEQLFPLAKE
FIDQYYSSIKRFGSKAHTDRLEEVNREIETTSTYQLKDTELIYGAKHAWRNASRCVGRIQ
WSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLI
RYAGYKQPDGSILGDPANVEFTDICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPEL
VLEVPIRHPKFTWFKELGLKWYGLPAVSSMLLEIGGLEFSACPFSGWYMGTEIGVRDYCD
NSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIK
HMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTN
GTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHA
FDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKS
YKVRFNSVSSYSDARKSSSDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVD
TLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISN
DRSWKRNKFRLTYVAEAPELTQGLYSIHKKRVSAARLLSRQNLQSPNSSRSTIFVRLHTN
GNQELQYQPGDHLGVFPGNHEDMVNALIDRLEDAPPANQLVKVELLEERNTALGVISNWT
DEHRIPPCTIFQAFKYYLDITTPPTPLQLQQFASLATNDKEKQRLLVLSKGLQEYEEWKW
GKNPTIVEALEEFPSVQMPSTLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAVVSYRTG
DGEGPIHHGVCSSWLNRIQPEEVVPCFVRGAPSFHLPRDPQVPCILVGPGTGIAPFRSFW
QQRLFDIQHKGMSPCPMVLVFGCRQSKIDHIYKEETLQAKNKGVFRELYTAYSREPDKPK
KYVQDALQEQLAETVYRALKEKGGHIYVCGDVTMAADVLKAIQRIMIQQGRLSAEEAGVF
ISKLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEWPSLLKYYSHTEGVN
WLEEYKARQSAGLEARRMVASFSKRFFSEHVPCNGFSDIEDLGCPGHFFEDELMSILNME
GRKALTWKYYAKKILYFLRQQKILKNLKAFLQRPEDHESFLEGAVLIDQYCNPLADICLK
DIQSQVESITDQVRKVLRGKNCRHPSLAFKAGGAMITESELQSQVLEAINCVLYDQLKYR
GNRMDYYNALNLYIHQVLSRRTGIPISLSVLYLTIARQLGVRLEPVNFPSHFLLRWCQGI
EGSQDIFDYIYIDAFGRGKQLTVKECEYLIGHHVTEEFYGVVSSKKVLQRMVGNLLSLGK
RESTDQSYQLLRDSLDLYLAMYPDHVQHLLLQARLYFHLGIWPEKVLDILQHIQTLDPSQ
HGAVGYLVQHTLEHIERKKEEIGLEVKHRSEEKHRDVCYSIGLIMKHKRYGYNCVIYGWD
PTCMMGHEWIRNMNVHSLPHGHHQPFYNVLVEDGSCRYAAQVSSDQIEQLHRRFKQLSGN
QLTIRTRRTQLTWMATRQSSWAFNHSSLQTDMFTSKENFNNIPDLELNPIRSKIIRAFFD
NRNLRKAPNGLADEINFEDFLTIMSYFRPIETNMDEEQLEHCRKEKLRFLFHMYDSDSDG
RITLEEYRNVVEELLSGNPHIEKESARSIADGAMMEAASVCVGQMQPDQVYEGITFDDFL
KIWQGIDIETKMHVRFLNMETIALCH
NT seq
6381 nt
NT seq
+upstream
nt +downstream
nt
atggaagaccacatgttcagtgttcaacaaattcagcccaacgtcatttccgtaagactg
tttaaacgcaaagtgggaggcttgggattcctggtgaaagaacgggtcagcaagcctccc
gtgattatctcggatctgatccggggtggggcagctgaacagagcggccttatccaggca
ggagacatcatccttgcagtcaatggccggcccttggtggacatgagctatgacggtgcc
ctggaggttctgaggagtattgcttcagagactcatgtggttcttatcctgagaggccct
gagggcttcactactcacctggaaactacattcactggggacgggacacccaagaccatc
cgagtgacccgacccttaggcccagccaccaagacggtggacctgtcccaccaggccgtt
cccagcaaagatcagcccccggggctggacagtgtggccaccctccgaaatgtgcctcaa
cgtccccgagaaaatggtcaagaagacaaccccctggcacaagccaacggcatggtacct
gaccccacaaagaagagtgcctcatctggcctgcatgggggtggggaaagcaacgacctt
ctccgagagatccagccagtgctgaacctgcttaccagtggcaagaaggagatcaatgga
gggcagtcacacaaggtggagaccaaggatgcagaagtccaggcagacagagatttggaa
ggaaagtcccacaaacttctgccacttggaatggagaatgatcgtgtcttcaatgatttg
tggggcaagaataacatgcctgttgtcttgaacaacccatattcagaaaaggaacagcct
ccaacctcgggaaggcagtcacctaccaagaatggcagtcctactaaatgtcctcgtttt
ctcaaagtcaaaaattgggaaacagatgtggttctcaatgacacactgcacctcaagagc
accttgaacacagcttgcactggacagatctgcatgggttccatcatgttcccctcccaa
cacatacggaagcctgaagatgtccggacaaaagagcaactctttcccttggccaaagag
ttcattgatcaatactattcatctataaagagatttggctccaaagcccacacagataga
ctggaagaagtcaacagggagatagaaaccaccagcacctaccagctgaaagacacagag
ctgatctatggagctaaacatgcctggagaaatgcttctcgctgtgtgggcaggatccag
tggtccaagctgcaggtgttcgatgcacgagactgtaccacagcccacgggatgttcaac
tacatctgtaatcatgtcaaatatgccacaaacaaagggaacctcaggtccgccatcacc
atatttccccagcggacagatggcaagcatgacttcagagtctggaactcccagctcatc
agatacgcaggttataagcagcctgatggcagcatcctaggagaccctgccaacgtggag
ttcacagatatatgcattcagcaaggctggaagcctccgagaggacgtttcgatgtcctg
ccgctcctgctccaggccaacggcaatgatcctgagctgttccagattcctccggagctg
gttttggaagtgcccatcagacatcccaagttcacatggttcaaggagctgggactgaag
tggtatggtctgccagctgtatccagcatgctcctggagatcggaggcctcgagttcagt
gcttgcccattcagcggctggtacatgggcactgagatcggcgtccgtgattactgtgac
aactcgcgatataatattcttgaggaagtggccaaaaagatgaatctggacatgaggaaa
acttcctccctgtggaaagatcaagccctagtggagatcaacattgcggtactctacagt
ttccagagtgacaaagtgacaattgttgaccaccattcagccaccgagtccttcatcaag
cacatggagaatgagtaccgctgccgaggaggatgtccggctgactgggtttggattgtc
ccacccatgtctggcagcatcacacctgtcttccaccaggaaatgctcaactatcgactc
acgccttcctttgagtaccagccagatccatggaacacccatgtctggaaaggtactaat
ggaacccccacaaaaagaagagccattggcttcaagaagttggcagaagctgtcaagttc
tcagctaagctgatgggtcaggccatggcaaaaagagtcaaagccaccattctctatgcc
accgagacaggcaaatcccaggcctatgcaaaaaccttgtgtgaaatcttcaaacatgcc
ttcgatgccaaggtcatgtccatggaagaatatgatattgtacacctagaacacgagact
ctggtcttggtggttactagcacctttggcaatggagatcctccagagaatggagagaaa
tttggctgtgctttgatggaaatgaggcaccccaactctgtgcaggaggaaaggaagagc
tacaaggtccggttcaatagtgtctcctcgtactccgatgcccggaaatcttcaagtgat
ggacccgacctgagagacaattttgaaagtgctgggcccctggccaatgtgagattctca
gtttttggccttggatcgagggcgtacccccacttctgtgcctttggccacgcagtggac
accctccttgaagaacttggcggggaacgcatcctgaagatgagggaaggggatgagctc
tgtggtcaggaagaagccttcagaacatgggccaaaaaggtcttcaaggcagcctgtgat
gtgttctgtgtgggggatgacgtcaacatagagaaagccaacaactccctcatcagcaat
gaccgaagttggaagaggaacaagttccggctgacctatgtggctgaagctccagagctc
acccaaggtctgtacagcattcacaaaaaacgagtatctgctgcccggctcctcagccgc
cagaatcttcaaagccctaattccagtcgttcaaccatctttgtgcgtctccacaccaat
gggaaccaagagctgcagtatcagcctggggaccatctaggtgtattccctggaaaccat
gaggacatggtgaatgccctgatcgatcgactcgaggatgcccctcctgccaaccagctg
gtgaaagtggagcttctggaggagaggaatacagctttgggtgtcatcagtaactggaca
gatgagcaccggattccaccctgcaccatcttccaggcctttaagtactacctggacatc
accacgcccccaacacccctgcagctacagcagtttgcttcattggccaccaatgacaag
gagaaacaacgactgctggtcctcagcaagggattacaggagtatgaggagtggaaatgg
ggcaagaaccccacgattgtggaggccttggaggaattcccatcggtgcagatgccatcc
actctcctgctgacccagctgtccctgttgcagccccgctactattccatcagctcctcc
ccggacatgtaccccgatgaggtgcacctgactgtggcggttgtgtcctaccgcactgga
gatggggaaggaccaatccaccatggggtctgctcttcctggctcaaccgaatacaacca
gaggaagtagttccttgttttgtccgaggagctcccagcttccacttgccccgagatccc
caggtaccctgtatcctagttggcccaggcacaggaatagcacctttccgaagcttctgg
cagcaaaggctatttgatattcagcacaaaggcatgtctccatgtcccatggtcctcgtc
tttgggtgtcggcagtctaagatcgaccacatctacaaggaggaaaccctacaggccaag
aacaaaggtgtcttcagagagctgtacacggcctattcccgtgagccagacaaaccaaag
aaatatgtacaggatgccttacaggaacagctggcagagactgtgtacagagccctgaag
gagaaagggggtcacatctatgtttgtggagatgtcacgatggccgccgatgttctgaaa
gccatccaacgcatcatgatccagcaggggaggctctcagcagaggaggctggggtgttc
attagcaaactgagggatgacaaccgctaccatgaagatatatttggggtcaccctgcgc
acatatgaagtgaccaaccgccttagatctgagtccattgcctttattgaagagagcaag
aaggacactgatgagtggccctccctcctgaagtactacagtcacacggaaggcgtgaac
tggctggaggagtacaaagctcggcagagtgcaggcttggaagcccgcaggatggtggcc
tccttctctaagcggttcttttccgagcacgtcccttgtaacggcttcagtgacattgag
gaccttgggtgcccaggacatttttttgaggatgaactgatgtccattcttaatatggaa
ggaaggaaagctttgacctggaaatactatgccaagaaaattctttatttcctacgacaa
caaaagatcttgaagaatctgaaggcatttcttcagcggcccgaggaccatgaatcattt
ctagaaggtgctgtgttaattgaccagtattgcaatcctcttgctgatatctgcttaaaa
gatatccaatcccaagttgagagtattacagaccaagttcgcaaagtccttcgtggaaaa
aactgtcgccaccccagtttggccttcaaggcaggtggggccatgataactgaaagtgag
ctccagagccaggtactcgaggccatcaactgtgtcctttatgatcagctcaagtaccga
ggaaaccgaatggattattacaatgccctgaatttgtatatccatcaggttttgagccga
agaacaggaatcccaattagtctctctgtgctctatttaacaattgccagacagctggga
gtccgactggagccagtcaatttccctagtcacttcttgctaagatggtgtcaaggtatt
gaagggagccaagatatttttgactacatttacatagacgcctttgggagaggaaagcag
ctgacggtgaaagaatgtgaatatctgattggccatcatgtgacagaggagttctatgga
gttgttagttctaagaaggtactgcagcgaatggtgggaaatctcttaagcctgggaaag
cgggaaagcacggatcagtcttaccagcttttaagagactccttggatctgtatctggcc
atgtatccagaccatgtacagcatcttttgctccaggccaggctctacttccatttggga
atttggccagaaaaggtgttggacatcctgcagcacatccagaccttggacccctcccag
cacggcgcggtgggctacttggtgcagcacaccctggagcacattgagcgcaagaaggag
gagatcgggctggaggtgaagcaccggtctgaagagaagcatcgggacgtctgctactcc
atcggcctcatcatgaaacacaagcggtatggctataactgtgttatctatgggtgggac
ccaacctgcatgatgggacacgagtggatcagaaacatgaacgtccacagcctgccccat
ggccaccatcagccgttctataacgtcctcgtggaagacggttcttgtcgctatgcagcc
caagtctcttcagaccaaatcgaacagcttcaccggaggttcaagcagctgagtgggaac
cagctgaccatccgaacaagaagaacccagctcacgtggatggccaccagacaaagcagc
tgggctttcaatcacagctccctacagacagatatgttcacaagcaaagaaaactttaac
aacatccctgacctggagctcaacccaatcagatccaaaatcatccgtgccttctttgac
aacaggaacctccgaaaagcacccaatggcttggctgatgagattaactttgaggatttc
ttgaccataatgtcttacttcagaccaattgagaccaacatggatgaagaacagttggag
cactgcagaaaggagaagttaagatttctgtttcacatgtacgactctgacagtgatgga
cggatcaccttggaagaatatcgaaatgtggtagaggaattgctttctggaaacccccac
attgaaaaggagtcagccagatccatcgctgatggagccatgatggaggctgccagtgtc
tgtgtgggtcaaatgcaaccggatcaagtgtatgagggaatcaccttcgatgacttccta
aagatctggcaggggattgacatagagaccaagatgcatgtccgcttcctcaacatggag
accatcgccctgtgccattga
DBGET
integrated database retrieval system
