Sarcophilus harrisii (Tasmanian devil): 100923530
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Entry
100923530 CDS
T02286
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00230
Purine metabolism
shr01100
Metabolic pathways
shr04022
cGMP-PKG signaling pathway
shr04024
cAMP signaling pathway
shr04924
Renin secretion
shr05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100923530 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100923530 (PDE3A)
04022 cGMP-PKG signaling pathway
100923530 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
100923530 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100923530 (PDE3A)
Enzymes [BR:
shr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100923530 (PDE3A)
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GFIT
Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
100923530
NCBI-ProteinID:
XP_003771223
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Position
5:115321115..115634582
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AA seq
1166 aa
AA seq
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MAPTGEVADIGDEPSSGREAQHQIPGSDCNGYSCKGKHLPLPPDSPSRPFRDQGCQVGWG
DIVLNKLRSSRKLSSALCAGSLSFLLAVVVRLVRGEISCDLEESQEEAEAVAAAAAAAAE
EEAAAAAAAAAAAEGGVLNLPRGGPLSGGWQLSAGLQPAALLFGFLCAFFWMGLYLLRSG
VRLPLALLLLAACCGGEAIVHIGLGVREDHLLSLPATGVVLSCLAAATWLVLKLRQGVLM
IFLISAVRTASLISLERVKVAWRPYLAYSAGLVGLLLARYPEKILPQSREAAQREGFGTQ
LIVGNKEEVAVFKRRRRSSSMISSEMSGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGYK
GSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQSIHKPR
VSPLVSFSENYTCSDSEEGSEKEKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLE
PAPVRRDRAGSNKSQEAPSSSAISPDSWNLMTMTKSRSFSTSYAVSAASHVNSKKQSRPG
VIAKISPRSSPNPSPIQGSPINSPVSKISAIQFPESAEVTPKQGLSSHRILTYTQSAPDL
SPQIFIPPVICTSCGRPYNQGNSADGALGSGSAATHSPNRTDDTAQVTSDYETNNNSDSS
DIVQNEDEQEGSKDSLRRESQHSTYTPETIVFMPDKPILAPEPLVMDNLDSIMEKLNTWN
FPIFDLVEKIGKKCGRILSQVSYRLFEDMGLFETFKIPVREFMNYFHALENGYRDIPYHN
RVHATDVLHAVWYLTTQPIPGLSTVINDHGSASDSDSDSGITHGHMGYVFSKMYSATDDK
YGCLAGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAA
WNLFMSQPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWT
NENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRS
APQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEDSDESGGDTDDREEAEQPTTEEETC
ENAESTGQQKFKRRKIYCQITQHLLQNHKMWKKVIEDEQRQGSGMEKLSLEKSTLHQSSE
QIQAIQEEEEEKRKTKGENTTTNLTQ
NT seq
3501 nt
NT seq
+upstream
nt +downstream
nt
atggccccgaccggagaggttgctgacatcggggatgaacccagcagtggcagagaagct
caacatcagatcccggggtccgactgtaacggttactcatgtaaaggcaagcatttgccc
ctgccccccgacagtccctcgagacctttccgggaccaaggctgccaggtcggctgggga
gacatagtcttgaacaagcttcggagctcccggaaactttcctctgcactctgcgctggc
tcgctctcttttttgctggcggtggtagtgaggctggtccgaggcgagatcagctgtgac
ctggaggagagtcaggaggaggcggaggcagtagcagcggcggcggcagcagcggctgag
gaggaagcagcagcagcagcagctgctgcagctgcagctgaagggggcgtcttaaatctg
cctcggggaggtccgctgagtggaggctggcaactcagcgctgggctgcagcccgcggcg
ctgctcttcggttttctgtgcgccttcttttggatgggcttgtatttgctccgctctggg
gtccgactgcctctcgcgctcttgctgttagccgcgtgctgcgggggggaagcaattgtc
cacatcggactgggagtccgcgaggatcacttactctctctccctgccaccggggtggtg
ctcagctgcttggccgccgcgacatggctggtgctgaagctgagacagggtgtcctcatg
atcttcttgattagtgcggtcaggaccgcgtccctgatttccttagagagagtcaaggtc
gcctggaggccgtacctggcttactcagccgggctggtggggctgcttctagccaggtac
ccggaaaaaatcttgcctcaatcgagagaagcggcccagagagaaggttttggcacccag
ctgattgtagggaataaagaagaggtcgcggtgtttaagaggaggaggcggtccagctcc
atgatctcctcagagatgtccggctgcagcagcaagtctcatcgcaggacctcccttccc
tgcatacctagggaacagctcatgggacattctgaatgggaccacaaacgagggtataaa
ggatcacagtcctcaggtacaagtattactgttgatattgctgtgatgggagaagcacat
ggccttattacggacctcctggcagatccttctttgccaccaaatgtgtgtacctcattg
agggctgtcagtaatttgcttagtacacagctgaccttccaatcaattcacaagccaaga
gtgagtcctttggtttccttcagtgaaaattatacctgttctgactcagaagaaggctct
gaaaaagagaaactcgctattcccaagcgcctgagaaggagtttgcctccgggattactg
agacgagtttcatccacttggacaaccaccacctcagccacgggcttgccaacactagag
cctgcaccagtgaggagagaccgggctggaagcaacaaatctcaggaagcaccttcatcc
agcgctattagccccgattcttggaatttaatgacgatgaccaaaagcaggtccttctct
acatcctatgctgtctctgcagctagccatgtgaattctaaaaagcaaagtcgaccaggt
gttatagctaaaatttcacctcgttcatctccaaatccatcacctattcaagggagtcca
atcaatagcccagtcagcaaaatttctgcgatacaatttccagaatctgcagaagtaact
cccaaacaaggtctaagctctcacagaattttgacatatacccagagtgcaccagatctt
tccccacagattttcatcccacctgttatatgtaccagctgtggcagaccatataatcaa
gggaactctgctgatggggcattgggaagtggcagtgcagccacacattcaccaaacagg
acagatgacacagctcaagtgacttctgactatgaaaccaataataacagtgacagcagt
gatattgtccagaatgaagatgaacaagagggctctaaagattcattgaggagagaatct
cagcacagcacatacactcctgaaaccatcgtgtttatgccagataagcctattcttgct
ccagagcctcttgtcatggataacttggactcaataatggaaaaactaaatacttggaat
ttcccaatctttgatttggtggaaaagatagggaaaaaatgtggccgaattctaagtcag
gtatcatatagactttttgaagatatgggactctttgaaacttttaaaattcctgtaaga
gaatttatgaattattttcatgccttggagaatggataccgggatattccttatcacaac
agagtccatgccactgatgttttacatgctgtttggtatcttactactcagcctattcca
ggcctctcaactgtgattaatgaccatggatcagcaagtgactcagattctgacagtgga
atcacacatggacacatgggatatgtattttcaaaaatgtattcagcaacagatgataaa
tatggatgcctggctggtaatatccctgccctagagttgatggctctctatgtggctgca
gccatgcatgattatgatcacccaggaaggacaaatgcttttctggttgcaactagtgca
cctcaggctgtactatataatgaccgttcagttttagagaatcatcatgcagctgctgca
tggaatctcttcatgtcccagccagagtataactttttagtcaaccttgaccatgtggaa
tttaagcatttccgtttccttgtcattgaagcaattttggccactgacctgaagaaacac
tttgattttgtagccaaattcaatgccaaggtgaatgatgatgttggcatagattggact
aatgaaaatgatcgcttattggtttgtcagatgtgcataaagttggcagatatcaacgga
cctgctaagtgtaaagaacttcatttacagtggacagatggtattgtcaatgagttttat
gaacagggtgatgaagaggccagccttggacttcccataagcccttttatggaccgttct
gctcctcagttggcaaatcttcaggaatctttcatctctcatatcgtggggccattgtgc
aatagctatgactctgcaggactgatgcctgggaaatgggtggaagacagtgatgaatca
ggaggagacacagatgacagggaagaagcagaacaaccaacaactgaagaagaaacttgt
gaaaatgctgaatcaacaggacagcagaagttcaaaaggaggaaaatctactgccaaata
actcagcacctccttcaaaatcataaaatgtggaagaaagtcattgaagatgagcaacga
caaggcagtggaatggaaaagctaagtctagaaaaatccactctgcatcaatcctcagag
caaatacaagcaatccaggaagaggaggaagaaaaaaggaaaaccaaaggagagaacaca
actacaaatttgacccagtga
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integrated database retrieval system
