KEGG   Sarcophilus harrisii (Tasmanian devil): 100924507
Entry
100924507         CDS       T02286                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00480  Glutathione metabolism
shr00980  Metabolism of xenobiotics by cytochrome P450
shr00982  Drug metabolism - cytochrome P450
shr00983  Drug metabolism - other enzymes
shr01100  Metabolic pathways
shr01524  Platinum drug resistance
shr05200  Pathways in cancer
shr05204  Chemical carcinogenesis - DNA adducts
shr05207  Chemical carcinogenesis - receptor activation
shr05208  Chemical carcinogenesis - reactive oxygen species
shr05225  Hepatocellular carcinoma
shr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:shr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100924507 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100924507 (MGST1)
   00982 Drug metabolism - cytochrome P450
    100924507 (MGST1)
   00983 Drug metabolism - other enzymes
    100924507 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100924507 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    100924507 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    100924507 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100924507 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100924507 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100924507 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100924507 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:shr02000]
    100924507 (MGST1)
Enzymes [BR:shr01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100924507 (MGST1)
Transporters [BR:shr02000]
 Other transporters
  Pores ion channels [TC:1]
   100924507 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 100924507
NCBI-ProteinID: XP_031794222
Ensembl: ENSSHAG00000001960
UniProt: A0A7N4UXX2
LinkDB
Position
5:111928416..111958070
AA seq 155 aa
MAEFPQLSDNQTFLAFISYSTIVISKMMLMSIITSFFRITRKAYANPEDALASGKGENAK
KFLRTDDRVERVRRAHLNDLENIIPFFCIGLLYSLSNPDFSTAVWHFRLFVAARIFHSIA
YLTPLPQPNRGLSWMIGYGVTFSMAYRLLKNKLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggctgaatttccccagctgagtgacaaccagactttcttggcttttatctcctattca
accattgtcatttcaaaaatgatgctaatgagtattataacatcattcttcagaataaca
agaaaggcttatgccaatccagaagatgccctagcctcaggtaaaggggagaatgctaag
aagtttcttcggacagatgatagagttgaacgtgtacgcagagcacacctgaatgatctt
gaaaatatcatcccattcttctgtattggcctgctatattccctgagtaatccagacttt
tccacagctgtatggcacttcagactctttgttgcagccagaatcttccactcaatcgct
tatttgacacctcttccacagccaaatcgtgggctgagttggatgattggatatggagtt
actttttcaatggcatacagattgttaaagaacaaattatacttgtaa

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