KEGG   Sarcophilus harrisii (Tasmanian devil): 100926529
Entry
100926529         CDS       T02286                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X3
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521  EGFR tyrosine kinase inhibitor resistance
shr01522  Endocrine resistance
shr04012  ErbB signaling pathway
shr04015  Rap1 signaling pathway
shr04062  Chemokine signaling pathway
shr04081  Hormone signaling
shr04137  Mitophagy - animal
shr04144  Endocytosis
shr04360  Axon guidance
shr04370  VEGF signaling pathway
shr04510  Focal adhesion
shr04520  Adherens junction
shr04530  Tight junction
shr04540  Gap junction
shr04611  Platelet activation
shr04613  Neutrophil extracellular trap formation
shr04625  C-type lectin receptor signaling pathway
shr04727  GABAergic synapse
shr04750  Inflammatory mediator regulation of TRP channels
shr04810  Regulation of actin cytoskeleton
shr04912  GnRH signaling pathway
shr04915  Estrogen signaling pathway
shr04917  Prolactin signaling pathway
shr04919  Thyroid hormone signaling pathway
shr04921  Oxytocin signaling pathway
shr04926  Relaxin signaling pathway
shr05100  Bacterial invasion of epithelial cells
shr05135  Yersinia infection
shr05152  Tuberculosis
shr05161  Hepatitis B
shr05163  Human cytomegalovirus infection
shr05167  Kaposi sarcoma-associated herpesvirus infection
shr05168  Herpes simplex virus 1 infection
shr05203  Viral carcinogenesis
shr05205  Proteoglycans in cancer
shr05207  Chemical carcinogenesis - receptor activation
shr05208  Chemical carcinogenesis - reactive oxygen species
shr05219  Bladder cancer
shr05417  Lipid and atherosclerosis
shr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:shr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100926529 (SRC)
   04015 Rap1 signaling pathway
    100926529 (SRC)
   04370 VEGF signaling pathway
    100926529 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100926529 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100926529 (SRC)
   04137 Mitophagy - animal
    100926529 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100926529 (SRC)
   04520 Adherens junction
    100926529 (SRC)
   04530 Tight junction
    100926529 (SRC)
   04540 Gap junction
    100926529 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100926529 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100926529 (SRC)
   04613 Neutrophil extracellular trap formation
    100926529 (SRC)
   04625 C-type lectin receptor signaling pathway
    100926529 (SRC)
   04062 Chemokine signaling pathway
    100926529 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100926529 (SRC)
   04915 Estrogen signaling pathway
    100926529 (SRC)
   04917 Prolactin signaling pathway
    100926529 (SRC)
   04921 Oxytocin signaling pathway
    100926529 (SRC)
   04926 Relaxin signaling pathway
    100926529 (SRC)
   04919 Thyroid hormone signaling pathway
    100926529 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    100926529 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100926529 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    100926529 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100926529 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    100926529 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    100926529 (SRC)
   05203 Viral carcinogenesis
    100926529 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    100926529 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100926529 (SRC)
   05168 Herpes simplex virus 1 infection
    100926529 (SRC)
   05163 Human cytomegalovirus infection
    100926529 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100926529 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100926529 (SRC)
   05152 Tuberculosis
    100926529 (SRC)
   05100 Bacterial invasion of epithelial cells
    100926529 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100926529 (SRC)
   05418 Fluid shear stress and atherosclerosis
    100926529 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100926529 (SRC)
   01522 Endocrine resistance
    100926529 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:shr01001]
    100926529 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:shr04131]
    100926529 (SRC)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100926529 (SRC)
Protein kinases [BR:shr01001]
 Non-receptor tyrosine kinases
  SRC family
   100926529 (SRC)
Membrane trafficking [BR:shr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100926529 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    100926529 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    100926529 (SRC)
  Macropinocytosis
   Kinases
    100926529 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 SH3_10 Haspin_kinase ABC1 DUF7063 SH3_3
Other DBs
NCBI-GeneID: 100926529
NCBI-ProteinID: XP_023363091
Ensembl: ENSSHAG00000017529
UniProt: A0A7N4PZR8
LinkDB
Position
2:430760340..430928127
AA seq 533 aa
MGSSKSKPKDPSQRRRSLEPTENVLHSGFPASQTPSKASVPDAHRTPNPPFGTTAPETKL
FGGFNTSDTVTSPQRSGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWL
AHSLTTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNSENPRGTFLVRESETT
KGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLTAYYSKHADGLCHR
LTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG
TMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGDMGKYLRL
PQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQ
GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYR
MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1602 nt   +upstreamnt  +downstreamnt
atgggaagtagcaaaagcaaacccaaagaccccagtcagcgacgccgaagcctggaaccc
accgagaatgtcctccacagtggcttccctgcttctcagacccctagcaaggcatctgtg
cccgatgcccaccgcactcccaacccaccctttgggaccacggcacctgagacaaagctc
tttggcggcttcaacacatcagacacagtcacctccccccagcgctcagggcctttggca
ggtggagtgaccactttcgtggccctatatgactatgaatcccgcactgagacagatctg
tccttcaagaaaggggaacgccttcagatagtcaacaacacagaaggagactggtggctg
gcccactcactcaccactggacagactggctacatccccagcaactacgtagccccatct
gattctatccaggccgaggagtggtattttggcaagatcacccgtcgggagtctgagcgg
ctgctgcttaattcggagaatccccgaggcacatttctggtccgggaaagtgagactacc
aaaggtgcctattgcctttctgtctctgacttcgacaatgccaagggcctcaatgtgaaa
cattataagatccgaaaactggacagtggaggcttctacatcacttcccgcacacaattt
aacagcctgcagcagctcacggcctactactccaaacacgctgatggcttgtgccacaga
ctcaccaacgtctgtccgacgtccaagccacagacccagggcctggcgaaggatgcctgg
gaaatcccccgggagtccctgcggttggaagtgaaactgggtcagggctgctttggagaa
gtgtggatggggacctggaatggcactaccagagtggcgataaagaccctgaagcctggc
accatgtccccagaagccttcttgcaagaagcacaggtcatgaagaagcttcggcatgag
aagctggtacagctgtatgctgtggtgtctgaggagcccatctacattgtcacagaatat
atgaacaaggggagcttgctggacttccttaaaggtgacatgggcaaatatcttcggctg
ccccagctggtggacatggctgctcagattgcatcagggatggcctatgtggaaaggatg
aactatgtccaccgagacctccgggctgccaacatcctggtgggagagaatctggtgtgc
aaggtggcagactttgggctggcccggctcattgaggacaatgagtacactgccagacaa
ggtgccaaatttcccatcaaatggacagccccagaagctgccctatatggccggttcacc
atcaagtctgatgtgtggtcctttggaatcctgctgactgagctgacaaccaagggtcga
gtgccatacccaggaatggtgaaccgggaggtactagaccaggttgagcgaggataccgg
atgccctgcccaccagagtgccctgaatccctgcatgacctcatgtgccagtgctggcga
aaggaccctgaagaacgccccacatttgaatacctgcaagcatttctggaggactacttc
acatccacagagccccagtatcagcctggggagaacctatag

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