Sarcophilus harrisii (Tasmanian devil): 100927125 Help Entry 100927125         CDS       T02286                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr04064   NF-kappa B signaling pathway shr04066   HIF-1 signaling pathway shr04145   Phagosome shr04151   PI3K-Akt signaling pathway shr04217   Necroptosis shr04613   Neutrophil extracellular trap formation shr04620   Toll-like receptor signaling pathway shr04621   NOD-like receptor signaling pathway shr04936   Alcoholic liver disease shr05132   Salmonella infection shr05133   Pertussis shr05134   Legionellosis shr05135   Yersinia infection shr05140   Leishmaniasis shr05142   Chagas disease shr05144   Malaria shr05145   Toxoplasmosis shr05146   Amoebiasis shr05152   Tuberculosis shr05161   Hepatitis B shr05162   Measles shr05164   Influenza A shr05170   Human immunodeficiency virus 1 infection shr05171   Coronavirus disease - COVID-19 shr05205   Proteoglycans in cancer shr05235   PD-L1 expression and PD-1 checkpoint pathway in cancer shr05321   Inflammatory bowel disease shr05323   Rheumatoid arthritis shr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100927125 (TLR4)    04066 HIF-1 signaling pathway     100927125 (TLR4)    04151 PI3K-Akt signaling pathway     100927125 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100927125 (TLR4)   09143 Cell growth and death    04217 Necroptosis     100927125 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100927125 (TLR4)    04620 Toll-like receptor signaling pathway     100927125 (TLR4)    04621 NOD-like receptor signaling pathway     100927125 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100927125 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100927125 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100927125 (TLR4)    05161 Hepatitis B     100927125 (TLR4)    05171 Coronavirus disease - COVID-19     100927125 (TLR4)    05164 Influenza A     100927125 (TLR4)    05162 Measles     100927125 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     100927125 (TLR4)    05135 Yersinia infection     100927125 (TLR4)    05133 Pertussis     100927125 (TLR4)    05134 Legionellosis     100927125 (TLR4)    05152 Tuberculosis     100927125 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     100927125 (TLR4)    05144 Malaria     100927125 (TLR4)    05145 Toxoplasmosis     100927125 (TLR4)    05140 Leishmaniasis     100927125 (TLR4)    05142 Chagas disease     100927125 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     100927125 (TLR4)    05321 Inflammatory bowel disease     100927125 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100927125 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100927125 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:shr04131]     100927125 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:shr04054]     100927125 (TLR4)    04090 CD molecules [BR:shr04090]     100927125 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:shr00536]     100927125 (TLR4) Membrane trafficking [BR:shr04131]  Endocytosis   Phagocytosis    Toll-like receptors     100927125 (TLR4) Pattern recognition receptors [BR:shr04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    100927125 (TLR4) CD molecules [BR:shr04090]  Proteins   100927125 (TLR4) Glycosaminoglycan binding proteins [BR:shr00536]  Hyaluronan   Cell surface receptors    100927125 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 LRR_14 TIR_2 LRR_5 LRR_EndoS LRR_9 LRR_Zer-1 ThsB_TIR LRR_NXF1-5 Motif Other DBs NCBI-GeneID:  100927125 NCBI-ProteinID:  XP_003757124 Ensembl:  ENSSHAG00000017208 UniProt:  G3WXY5 LinkDB All DBs Position 2:439946977..439958700 Genome browser AA seq 828 aa AA seqDB search MVRWIAMALIITTTFFSCLDPGSCHSCLEVFPDIEYQCMARNFSEVPVDIPSSTQKLDLS FNPLKSLASRSFSRFTGLRILDLSRCDIQKIEDDTYQGLCNLSTLILTGNPIQSLGLRAF HGLPKLQKLVVVETNLVSLKDFPIGHLMTLQELYLGHNSISSLKLPHYFASFSSLQHLDL HLNLINNISDGDLEPIKMNLNLTLDLSQNPIQYIHPGVLKGIHLTGLILRGNFHSSAVME VCIKGMTGLQVNKLVLGNYKNEFQMTNFESKILDGLCQVDIDEFWMVVPSDFPSDSYGFF RCLVNVSVLHMVTVPLEVLTNLPVFPKLFSLVFTNCKFETLPTLPSTSLPSLKELRITRH KDLTTLSDLKLPSLELLDLSQNALNILSCCSYNNFDTDKLKYLNLSYNAQIMLSKNFMGF ENLESLDLQHCQLKGHNNFPVFLSLTKLQYLDISYTNTHVQFENIFAGLSNLRHLKMAGN FFQGNILQDIFKNLSQLVTLNISYCHLEKIPQITMKSLHQLQVLDISHNNLQTFEPLIFR PLWNLQVLNCSYNSITALDGQNLQSLSETLVSTDFSGNPFDCVCDHQIFFQWVKENIQLL NRSKPMICQTPSHMKDVSVLLFDDLYCQMKKTIIAMSILAIMLVLMALALVYKFYFHLML LAGCKKMVGEESTYDAFVIYSSQDEEWVRKELVKNLEEGVPSFQLCLHYRDFIPGVAIAA NIIQEGFHKSRKVIVVISKHFIQSRWCKFEYEIAQTWQFLSSHAGIIFIMLQKVEKSLLR QQVELYRLLRRNTYLEWENTNLGRHVFWRRLRKALLDGRTKRQKEAAE NT seq 2487 nt NT seq  +upstreamnt  +downstreamnt atggtccgttggatagccatggctctgattataaccacaaccttcttttcctgtctggat ccggggagttgtcattcctgcctagaggtttttccagacattgaataccaatgcatggcc cgaaatttctctgaagttccagtggatataccttcatccacccagaagctggacctgagc ttcaacccactgaagtctttggcttcacgaagtttttccagatttactggactgagaata cttgacttgtccagatgtgatattcagaagattgaggatgacacttatcaaggcctctgt aatctctctactttgatcctgacgggaaacccaatccagagtttgggtctcagagccttc catggtcttcccaagttacagaagctggttgttgtagaaacaaatcttgtgtctctgaag gacttccccattggacatctcatgaccctgcaggagctatatttaggacataattccatc agttctctcaagttaccccattattttgccagtttcagctccctgcagcatctggatctt cacttgaatttgataaataatatttctgatggagatttagagcctataaagatgaatcta aatctcactctagacctttctcagaatcctattcaatatatccatccaggcgtcttaaag gggattcacttaactggactaattctgagaggaaattttcacagttcagcagtcatggag gtttgtattaagggaatgactggcttgcaagtcaacaaactggttcttggaaattacaaa aatgaattccaaatgactaactttgagagcaagatcctagatgggttgtgtcaggtggac attgatgaattttggatggttgttccctctgattttccttcagatagttatggatttttc agatgtttagtcaatgtttctgttctccatatggttacggttcccttagaagtgctgact aacctaccagtatttcctaaactgttctcattggtattcactaactgcaaatttgaaaca ctgcctaccttaccatctacctctctcccctcccttaaagaacttcgtattactcgccac aaagatctcacaactttgtctgatttgaaacttcccagtctggagcttctggacctcagt caaaatgctctgaatattttgtcctgctgttcctacaataactttgatacagacaaactg aaatatttgaacttaagttataatgctcaaatcatgttgagtaagaacttcatgggtttt gaaaacctagaatctctggatcttcaacattgccaattgaaaggtcataacaatttccct gtctttttatcactcacaaaacttcagtacctggatatttcttatacaaacactcatgtc caatttgaaaatatttttgcaggtttgagcaatttaagacatttgaaaatggctggtaac tttttccagggcaacattttacaagacatcttcaagaatctgagtcagcttgtcacacta aatatttcctactgtcacctagaaaaaatcccccaaataacaatgaagtccctccatcaa ctccaggtgttggatattagccataacaacctccagacttttgaaccactcattttcagg cctctttggaacctccaagtcttgaactgcagttacaacagtatcacagccctggatggg cagaatttacagtcattgtcagaaactctggtttctactgatttttctggaaatcccttt gattgtgtctgtgaccatcaaatcttctttcagtgggtcaaagagaatatacaactcttg aatagatctaaaccaatgatttgccagacaccttctcatatgaaagatgtctctgtgcta ttatttgatgatttatattgtcagatgaaaaagactatcattgctatgtcaattttggca ataatgttggtacttatggcactggccttggtctataagttctatttccacctgatgctg cttgctggctgcaaaaaaatggttggagaggaaagcacttatgatgcttttgtgatctat tctagtcaagatgaggaatgggtgaggaaggaattggtgaaaaacctagaagagggtgtt ccctcattccaactctgcctccactaccgagactttatccctggtgtggctattgctgcc aacattattcaggaaggtttccataagagtcggaaggtcattgttgtgatctccaagcac tttatccagagccgctggtgcaagtttgagtatgaaattgctcagacatggcagttcctg agcagtcacgcaggtatcatcttcatcatgctacagaaagtggaaaaatcactactgcga caacaggtggaactctaccggctgcttcgtcgaaacacctacctggaatgggagaacact aacctgggtagacatgtgttttggagacggctgagaaaagcattgttagatggcagaaca aagaggcagaaagaagcagctgaataa

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