Sarcophilus harrisii (Tasmanian devil): 100927743
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Entry
100927743 CDS
T02286
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04217
Necroptosis
shr04380
Osteoclast differentiation
shr04620
Toll-like receptor signaling pathway
shr04621
NOD-like receptor signaling pathway
shr04630
JAK-STAT signaling pathway
shr04658
Th1 and Th2 cell differentiation
shr04659
Th17 cell differentiation
shr05145
Toxoplasmosis
shr05160
Hepatitis C
shr05161
Hepatitis B
shr05162
Measles
shr05164
Influenza A
shr05165
Human papillomavirus infection
shr05167
Kaposi sarcoma-associated herpesvirus infection
shr05168
Herpes simplex virus 1 infection
shr05169
Epstein-Barr virus infection
shr05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100927743 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100927743 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100927743 (TYK2)
04621 NOD-like receptor signaling pathway
100927743 (TYK2)
04658 Th1 and Th2 cell differentiation
100927743 (TYK2)
04659 Th17 cell differentiation
100927743 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
100927743 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
100927743 (TYK2)
05160 Hepatitis C
100927743 (TYK2)
05171 Coronavirus disease - COVID-19
100927743 (TYK2)
05164 Influenza A
100927743 (TYK2)
05162 Measles
100927743 (TYK2)
05168 Herpes simplex virus 1 infection
100927743 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100927743 (TYK2)
05169 Epstein-Barr virus infection
100927743 (TYK2)
05165 Human papillomavirus infection
100927743 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100927743 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100927743 (TYK2)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100927743 (TYK2)
Protein kinases [BR:
shr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100927743 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
FERM_C_FAK1
RA
RA_2
Motif
Other DBs
NCBI-GeneID:
100927743
NCBI-ProteinID:
XP_031803363
Ensembl:
ENSSHAG00000007617
UniProt:
G3W042
LinkDB
All DBs
Position
1:complement(646991272..647005401)
Genome browser
AA seq
1196 aa
AA seq
DB search
MPLCHCAARHSDSDGEWGHPSSSGLKVLLHWSNGGDQYVTYNQGTMTAEEVCIHIAQKVG
ITPLCYNLFALYDTQAQVWLPPNHLFEITKDTNQTLQFRMRYYFRNWHGLNTQEPAVYRS
MPRGFEVSEEKTRIEQGCALLDKASFEYLYEQGKFEFVNDVASLSDLHSDAEVQHFKNES
LGMAVLHLSHLALQRGVPLEEVVRKTSFKDCIPCSFSRQIQQNNSLTKFRLRNVFQKFMR
RFHLQTVGPGRFSEQDIMFKYLATLEQLAPRFGTERFLALTLALPTEAERDLCYVNSSEQ
GPTLPPGATLSLADQAPTHEVLVTGTSGIHWRLLQVEDSDLKVNHSQSSLGKKSKTREAE
SRKLSQLPTERKETVWTYFCDFQDITHIVVKENNVSIHRQDNKCLELTLPSPMVALSLVS
LVDGYFRLTADSSHYLCHEVAPPRLVMSIQNGIHGPLQEPYVLSKLKREEVEDGLYLIRW
SSFDFHRLILTVARKDQAAGAQGLRYKQFRIEEQGLTFQLEGWDQAFPSVRELTAALQGC
TLRSSSGSGPGSTLESFTLSKCCLPRAGEISNLIITRQRPKEGPKSLNLSQLSFHQIRKE
EITQLAHLGQGTRTNIYEGLLHVGGGMGAEDEEDENIPSEPNNNHRELRVVLKVLDPSHR
DIALAFFETASLMSQVSHIHLAFVHGVCVRGSENIMVAEHVEHGPLDVCLRREKGHVPVA
WKITVAQQLASALSYLEDKNLVHGNVCAKNILLARRGLGDGTQPFIKLSDPGVSVTALSR
EERVERIPWIAPECVPSGTGLSTAADKWSFGTTLLEICFDGEAPLQGRSPSEKERFYEKK
HRLPEPSCKELATLISQCLTYDASQRPSFRTILRDLTQLQPQNLDITTMSPEFPASDPTI
FQKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKSLKAGCSSQLLSSWQREIEIL
RTLYHEHIVKYKGCCSDQGEKMVQLIMEYVPLGSLRDYLPKHSLGLAQILLFAQQICEGM
AYLHSQHYIHRDLAARNVLLENDNTIKIGDFGLAKAVPEGHDYYCVREDGDSPVFWYAME
CLKECKFYYASDVWSFGVTFYELLTRCDCNQTPPLKFIEMIGVTQGQMTVLRLIDLLERG
QRLPCPKDCPCEIYLLMKNCWESEASFRPTFQNLVPLLKTFHEKYRSQAPSVFSVC
NT seq
3591 nt
NT seq
+upstream
nt +downstream
nt
atgccattatgtcactgtgctgcaagacacagtgactctgatggagagtggggccatccc
agcagcagcgggctcaaggttcttctccactggagcaatgggggtgaccagtatgtgacc
tacaatcagggtaccatgactgcagaggaagtctgcattcacattgcacagaaagtggga
atcactccactctgctacaacctctttgcattatatgatacccaggctcaagtctggctg
cctcctaaccacctctttgagatcaccaaggataccaatcaaaccctgcagtttcgaatg
aggtattacttcaggaactggcatgggctgaacactcaggagccagctgtgtacagaagc
atgcctcgaggttttgaggtctctgaagagaagacccggattgagcaggggtgtgctttg
ctggacaaagcctccttcgagtacctctacgaacagggaaagtttgagtttgtcaatgat
gtcgcatccctttcggacctgcacagtgacgcagaggttcagcacttcaagaacgagagc
ttgggcatggccgtgctgcacctttcccaccttgctctgcagcgcggcgtgcccctggaa
gaggtggtgaggaagaccagcttcaaagactgcatcccctgttccttcagccgacaaatc
cagcagaacaattccctgactaagttccgcctaaggaacgttttccagaagtttatgcga
cgattccatctgcagacagtgggtccggggcgttttagtgaacaggacattatgttcaaa
tacctggctacactggaacagctggccccgcgctttggcactgaacgcttccttgccctg
accttggcgttgcccacggaggctgaaagggatctgtgctatgtcaacagcagtgagcaa
gggcctacgcttccaccgggagctactctctctctcgctgaccaggctcctacccatgag
gttctagtgactgggacaagtggtatccattggcggcttcttcaggtggaggactctgac
ttgaaagtcaaccactcccaaagctcccttggtaagaagtccaagacccgggaggcagaa
agccggaagctgagccagttgcccactgagaggaaagagactgtctggacatatttttgt
gacttccaagatatcacccatattgtggtcaaggagaacaacgtcagcatccaccgtcag
gacaacaagtgcctggaactgactctcccttcacctatggtggcactctctctggtatcc
ctggttgatggctacttcaggctgacagcagactccagccactacctgtgccatgaggtg
gcccccccgaggctggtgatgagcattcaaaatggcatccatgggcccctgcaggagcct
tatgtactgtccaaactgaagcgagaggaagtagaggatggcctctaccttatccgctgg
agttcctttgacttccaccgcctcatcctgactgtggcccggaaagaccaggcagctgga
gcacagggtctccgttacaagcagttccgcattgaagagcagggcctgaccttccagctt
gaaggctgggatcaagcctttcccagtgttcgtgagctcactgcagccctacaaggctgc
acactgcgatccagctctggctctggtcctggctctaccctagagagcttcacactcagc
aaatgctgcctgcctcgagcaggagaaatttccaatctgatcattactcggcagcgtcct
aaggagggtcccaaatcacttaacttgtcccagctcagcttccatcagatccgaaaggaa
gaaatcacccagctggctcacctgggccaaggcacccggaccaatatttacgagggactc
ctgcacgtggggggtggaatgggagctgaggatgaggaagatgaaaacattccctcagaa
cccaacaacaaccatcgggagcttcgagtagtgctaaaggtgttggatccaagtcaccgc
gatattgctctggcattttttgagacagccagcctaatgagccaggtctcccacatccac
ctggccttcgtccatggtgtttgtgtccggggctctgagaacatcatggtggcagaacat
gtagaacatgggcccctggatgtatgtctgcggcgggagaagggccatgtgccagtggcc
tggaagattactgtggcccagcagcttgccagtgctctcagctacctagaggacaaaaac
ctggttcacggcaacgtctgtgccaagaacatcctgctggcaaggcgaggccttggggat
ggcactcaacccttcatcaaactcagtgatcctggcgtcagcgtcacggccctctccagg
gaggagcgggtagagcgcattccctggatcgcccccgagtgtgtccccagcgggacgggt
ctcagcacagccgctgacaagtggagctttggaacgacactgttagagatctgctttgat
ggggaagcgcctctccagggtcgtagcccttctgagaaggagcgattttatgaaaagaag
catcggctccctgagccctcatgcaaggagctggccacgctcatcagccagtgcctcacc
tatgatgccagccagcggccctccttccgaaccatcctgcgtgatctcacgcagctgcag
ccccagaatcttgacatcaccaccatgagcccagagttcccagcctcagatcccaccatt
tttcagaaacgctacctgaagaagatccgggacctgggagagggccactttggcaaggtg
agcctctactgctatgacccaactaatgatggcacaggggagatggtggctgtgaagtct
ctcaaggctggctgcagttcccagctcctgagcagctggcagcgggagattgagatcctc
cggacgctctaccacgagcacatcgtcaagtataagggctgctgcagtgaccaaggggag
aagatggtccagctgatcatggagtatgtgccactgggcagcttgcgggattatctcccc
aaacacagcttggggctggcccagattctgctgtttgctcagcagatctgtgagggcatg
gcctacctccattcccaacactacatccaccgagacctggcagcccgaaatgtccttctg
gagaatgacaacactatcaagattggggactttggtctggccaaggctgtgccagagggc
cacgattattactgtgtccgggaggatggagacagccctgtcttctggtatgctatggag
tgtctcaaggagtgtaagttctactacgcctccgacgtctggtcctttggggtcaccttc
tacgaactgctgacacgctgtgactgcaatcaaaccccacccttgaaattcatcgaaatg
attggggtcacccagggccagatgacagtgctgaggctcatagacctgctagagagaggc
caaagactgccttgtcccaaggactgtccctgtgagatctatcttctcatgaagaattgc
tgggaatctgaagcctccttccgcccaaccttccagaaccttgttcccctcctcaagaca
ttccatgagaagtatagaagtcaagctccctctgtgtttagtgtatgctga
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integrated database retrieval system
