Sarcophilus harrisii (Tasmanian devil): 100927789 Help Entry 100927789         CDS       T02286                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr00220   Arginine biosynthesis shr00330   Arginine and proline metabolism shr01100   Metabolic pathways shr04020   Calcium signaling pathway shr04066   HIF-1 signaling pathway shr04146   Peroxisome shr04371   Apelin signaling pathway shr04926   Relaxin signaling pathway shr05010   Alzheimer disease shr05014   Amyotrophic lateral sclerosis shr05022   Pathways of neurodegeneration - multiple diseases shr05133   Pertussis shr05140   Leishmaniasis shr05142   Chagas disease shr05145   Toxoplasmosis shr05146   Amoebiasis shr05152   Tuberculosis shr05200   Pathways in cancer shr05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:shr00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     100927789 (NOS2)    00330 Arginine and proline metabolism     100927789 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     100927789 (NOS2)    04066 HIF-1 signaling pathway     100927789 (NOS2)    04020 Calcium signaling pathway     100927789 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     100927789 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     100927789 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100927789 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     100927789 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     100927789 (NOS2)    05152 Tuberculosis     100927789 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     100927789 (NOS2)    05145 Toxoplasmosis     100927789 (NOS2)    05140 Leishmaniasis     100927789 (NOS2)    05142 Chagas disease     100927789 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100927789 (NOS2)    05014 Amyotrophic lateral sclerosis     100927789 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     100927789 (NOS2) Enzymes [BR:shr01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      100927789 (NOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 NAD_binding_6 Motif Other DBs NCBI-GeneID:  100927789 NCBI-ProteinID:  XP_012405248 Ensembl:  ENSSHAG00000008893 UniProt:  G3W4E3 LinkDB All DBs Position 4:complement(434390745..434433647) Genome browser AA seq 1153 aa AA seqDB search MREGVSSACAMPRMCLLIKRIFGSHPMCCANGSSSQTEDDVKSHSLSKPRNEQQQTTLVE EKKPPEPQVKGIHPVSGCPRHVRVKNWSNGMTFQDTLHHKAKLDIDCKSKACRGSIMTPK SMTKGTRDRATSPEELLPQAIDFVNQYYGSFKEAKIEQHLARVEAVTKEIETTGTYQLTE DELIYATKQAWRNAPRCIGRIQWSNLQVFDARKCTTAKEMFEHICQHIRYATNNGNIRSA ITLFPQRSDGKHDFRVWNAQLLRYAGYQMPDGSIVGDAASTEFTQLCIDLGWVPKYGRFD ILPLVLQANGQDPEVFEIPKDLVLEVSIEHPKYEWFKELDLKWYALPAVANMLLEVGGLE FPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVIEINVAVL HSFQKQNVTIMDHHSAAESFMKYMQNEFKSRGGCPADWVWLVPPISGSITPVFHQEMLNY VLSPFYYYQVEAWKTHVWHDEKKRPKKREIKLKVLIKAVFFASVLMRKTVAARINVTVLF ATETGKSETLARDLGDLFSCAFNSKVLCMDEYKLSDLEKEKLLLVVTSTFGNGDSPGNGE KLKKSLFLLKELKNKFRYAVFGLGSSMYPQFCAFAHDIDEKFLQLGASQLAPTGEGDELS GQDEAYRSWALNTFKVACETFSIQGRETIQIPKLYTTNETWNPENYRLVQDPQPLDLNKA LSSMHAKNVFSMRLKSRQNLQSLKSSRATLLIKLSCEGNQNLNYIPGEHLGVFPGNQPTL VQGILERVKDGPSPHQSVRLETRDENGDYWISDKKLPPCSLSQALTYFLDITTPPTQLLL RKLAQLTTSEEEKRRLEALCQTSEYNKWKFTNVPTFLEVLEEFPSIQISATFLLTQLPLL KPRYYSISSSRDLTPKEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNNLKLQETVPCFVRS ASGFQLPENPSHPCILVGPGTGIAPFRSFWLQRLADREKKGLKNPNMTLVFGCRHPDMDH LYREEMKEMTQKGVLRDVYTAYSRQPGQPKVYVQDILRQRLADEVIRTLHEEKGHLYVCG DVRMARDVAQTLKDLFATRLKMNEEQTENYFFQLKSQKRYHEDIFGAVFPYEVKTDQAAS KPEETKLSKAGLS NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgagggaaggggtcagctctgcctgtgccatgccaaggatgtgcctgctgattaaaagg atctttgggagtcatcctatgtgctgtgcaaatggatccagttcacagacagaggatgat gttaagtctcacagcctgagtaaacctcggaatgagcagcaacaaacaactttggtggag gaaaagaagcctcctgaaccccaggtcaaggggatccatcccgtatcaggctgtccaagg cacgtgagagttaaaaactggagtaatggaatgacattccaagacactctacatcacaaa gccaaactggatattgattgcaagtccaaggcttgtcgagggtcaataatgacccccaag agtatgacaaaagggactagagacagagcgacctctccagaagagctgctacctcaagcc atcgactttgtcaaccagtattacggctccttcaaagaggcaaaaatagagcagcatttg gccagagtggaagcagtaacaaaggagatagaaacaacaggaacctaccagctgacggaa gatgagctcatttatgcaaccaagcaggcctggagaaatgcccctcggtgcattggaagg atccagtggtcaaacctgcaggtgtttgatgctcggaaatgtacaacagccaaggagatg tttgagcacatctgtcagcacatccgctatgcaaccaacaatggaaatatcaggtcagcc attaccctcttccctcagcggagtgatgggaaacatgacttccgggtctggaatgctcag ctccttcgatatgctggctatcagatgccagatggttctatcgtgggtgatgctgccagc accgagttcacccagctgtgtatagacttgggatgggtgcccaaatacggccgctttgat atcttgcctctcgtgttacaagccaatggacaggacccagaggtctttgagatcccaaaa gaccttgtcctcgaggtgtctatagaacatcccaagtatgagtggttcaaggagctggat ctgaagtggtatgctctgcctgctgtggccaacatgctcctggaagtgggcggccttgag ttccctgggtgcccattcaatggctggtacatgggaactgagattggtgtccgagatttc tgtgatgtccagaggtacaatatcctggaggaagttggaaggaggatgggtctggaaacg cataaattggcttccctctggaaggacagggcagtgattgagatcaacgtggccgtgctg catagtttccaaaaacaaaatgtcaccatcatggatcaccattcagctgcagaatctttc atgaaatatatgcagaatgaattcaagtctcgaggcggttgcccggcagattgggtctgg ctggtccctccaatctctgggagcatcactcctgtgtttcatcaggagatgctaaactac gttctttctcctttctactactaccaggtggaggcctggaaaacccatgtctggcatgat gagaagaagaggcccaaaaaaagagagatcaaattaaaggtcttgatcaaagcagtgttc tttgcctctgtcctgatgcgcaagactgtggcagctcggatcaacgtcactgtgcttttt gcgacagagacaggcaaatcagaaactctggccagggatttgggagacttgttcagctgt gctttcaatagcaaggttctctgtatggatgaatacaaactgagtgatctagaaaaagag aagctacttctggtggttaccagcacttttggaaatggagattctcctgggaatggtgag aaactgaagaagtccctgtttctcctgaaggagctaaaaaataaattcagatatgctgtg tttggtctcggctccagtatgtatccccagttttgtgcctttgcccatgatatcgatgag aagtttttgcaattgggggcctctcaacttgcaccaactggagaaggagatgaactcagt ggacaagatgaagcctaccgtagctgggcactgaataccttcaaggtggcctgtgagacc ttcagcatccaaggaagggaaacaattcagatccccaagttatatactaccaatgaaacc tggaaccctgaaaattaccgtcttgtacaggatccccaacctctggacctcaacaaagcc ctcagcagtatgcacgccaagaacgtgttttccatgcggctcaaatcgagacagaatctg cagagtctcaaatccagccgggcaaccctcctcattaaactttcctgtgaaggaaaccag aatctgaattatataccaggagagcatcttggggtttttcctggaaaccagcccacccta gttcagggtattttagaacgagttaaggatggcccatcacctcaccaatctgtgcgctta gaaacccgtgatgagaatggtgactactggataagtgataagaagcttcccccctgctcg ctcagccaagccctaacttatttcctggatatcaccacccctccaacccagctgctgctc agaaagttggctcagctgaccacctcagaggaagagaagagacgtctggaggcactgtgc cagacctctgaatacaataagtggaagttcacaaacgtccccacgttcctggaggtgctg gaagagtttccttccatccagatctcagcgactttcctgctcacacagttgcccctgctg aagccccgctactattccataagctcctctcgggacctcacccccaaggagatccacctg actgtggctgtggtcacttaccataccagagacggtcagggccctctccatcatggggtc tgtagcacatggctcaacaacctgaagctccaggaaaccgtgccctgttttgtacgaagt gccagtggcttccagctcccagagaatcccagtcacccctgcattctggtgggaccgggc accggtatcgcccccttcaggagtttttggctacagcgactggcggacagagagaagaaa ggtctcaagaaccccaatatgacgttggtgtttggatgccggcaccccgacatggaccac ctgtatcgagaggagatgaaggagatgacacagaaaggagtgctccgggatgtctacaca gcctactcccgccagcccggccagcccaaagtctatgttcaggatattctgcggcagcga ctggcagatgaggtgattcggacattgcatgaggagaaggggcacctgtatgtctgtgga gatgtgaggatggccagagatgtggcccaaactctgaaggatctctttgccaccagactg aaaatgaatgaagagcagactgagaactatttcttccaactcaagagtcagaagcgttac cacgaagacatctttggggctgtctttccctatgaggtgaaaactgaccaagcagcatca aaacctgaagagaccaagctctctaaggcaggactcagctag

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