Sarcophilus harrisii (Tasmanian devil): 100929098
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Entry
100929098 CDS
T02286
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00020
Citrate cycle (TCA cycle)
shr00480
Glutathione metabolism
shr01100
Metabolic pathways
shr01200
Carbon metabolism
shr01210
2-Oxocarboxylic acid metabolism
shr01230
Biosynthesis of amino acids
shr04146
Peroxisome
shr05230
Central carbon metabolism in cancer
Module
shr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
shr_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100929098 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100929098 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100929098 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100929098 (IDH2)
Enzymes [BR:
shr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
100929098 (IDH2)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
100929098
NCBI-ProteinID:
XP_031811463
Ensembl:
ENSSHAG00000011631
UniProt:
G3WDV3
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Position
2:complement(547716236..547735917)
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AA seq
455 aa
AA seq
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MAGYLRVARSLGKTRASAPGRSPGALTPAALSLQGGQPRRDYADKRIKVDKPVVEMDGDE
MTRIIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTNDQVTIDSALATQKYSVAVKCATIT
PDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGD
QYKATDFVVDKAGTFKMVFTPKDGSGVKEWDVYNFPAGGVGMGMYNTDESISGFAHSCFQ
YAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQV
LKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRE
HQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAG
CIHGLSNVKLNEHYLNTEDFLDTIKKNLDKALGQK
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atggcgggctacctgcgcgtcgcgcgctccctcggcaagacccgcgcctcggcgccgggc
agaagcccgggggccctgaccccggcggcgctgagcctgcaaggagggcagccgcgccgc
gactatgcagacaaacgaatcaaggtggacaaacctgtggtggagatggatggagatgag
atgactcgaatcatctggcagttcatcaaagaaaagcttatcctaccccatgtggatgta
cagctcaaatactttgacctggggctcccacaccgtgaccagacaaatgaccaggtcact
attgactcagccctagccacccagaaatatagtgtggctgtcaagtgtgctaccattact
ccagatgaagcccgtgtggaagaattcaagctaaagaagatgtggaaaagtcccaatggg
actataagaaacattctaggaggaacggtattcagagaacccataatctgcaagaacatc
ccccgtcttgtccctggttggaccaagcccatcaccatcggcaggcatgcccatggggat
cagtacaaggccactgactttgtagtagacaaggcaggtactttcaagatggtgttcact
cccaaagacggcagtggcgtaaaggagtgggacgtgtacaacttccctgctggaggtgtg
ggcatgggcatgtacaacactgatgagtctatctcaggttttgcacacagctgcttccag
tacgccatccagaagaagtggcccctctacatgagcaccaagaataccattctgaaggcc
tatgacggtcgcttcaaagacatcttccaggaaatctttgacaagcactacaagacagat
tttgacaagaacaagatttggtatgagcaccgactcattgatgacatggtcgctcaggta
ctcaagtcttcaggtggatttgtctgggcctgcaagaattatgatggcgacgtgcagtct
gatatactagcccagggctttggttcccttggtctgatgacttcggttctggtctgcccc
gatgggaagaccattgaggcagaagctgcccacggaactgtcacccgccattaccgggag
caccagaagggccgacccactagtaccaatcccattgctagcatctttgcctggacaaga
ggcttagagcaccgaggaaagctggacggcaaccaggacttaattagatttgctcagact
ctggagaaggtatgtgttgagacagtggagagcggagctatgaccaaggatctcgccggc
tgtatccatgggctaagcaacgtgaagctgaacgagcactatctgaatactgaggatttc
ctggacactatcaagaagaatttggacaaagctctgggccagaaatag
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