Sarcophilus harrisii (Tasmanian devil): 100930047
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Entry
100930047 CDS
T02286
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X2
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04012
ErbB signaling pathway
shr04014
Ras signaling pathway
shr04110
Cell cycle
shr04360
Axon guidance
shr04517
IgSF CAM signaling
shr04722
Neurotrophin signaling pathway
shr05200
Pathways in cancer
shr05206
MicroRNAs in cancer
shr05208
Chemical carcinogenesis - reactive oxygen species
shr05220
Chronic myeloid leukemia
shr05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100930047 (ABL1)
04014 Ras signaling pathway
100930047 (ABL1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
100930047 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100930047 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100930047 (ABL1)
09158 Development and regeneration
04360 Axon guidance
100930047 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100930047 (ABL1)
05206 MicroRNAs in cancer
100930047 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
100930047 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100930047 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
100930047 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100930047 (ABL1)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100930047 (ABL1)
Protein kinases [BR:
shr01001
]
Non-receptor tyrosine kinases
ABL family
100930047 (ABL1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
ABC1
SH3_6
Motif
Other DBs
NCBI-GeneID:
100930047
NCBI-ProteinID:
XP_023350075
Ensembl:
ENSSHAG00000016375
UniProt:
A0A7N4PWI8
LinkDB
All DBs
Position
2:482326869..482499826
Genome browser
AA seq
1126 aa
AA seq
DB search
MKMLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVTASDFEPQGLSEAARWNSKENLLAG
PSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYIT
PVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRIN
TASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTIYGVSPNYDKWEI
ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPN
LVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKK
NFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS
IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKNYRMERPEGCPEKVYELMRACWQ
WSPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKVVRSVVSTLLQAPELPTKTRTSRR
AAENKDTSELLDTSHLRSQGEDLLDHEPAVSPLLPRKERVPQDSNLNEDERLLPKDKKTN
LFSALIKKKKKTAPTPPKRSSSFREMDGHSDRRAGGEDETRDILNGTFITAPSDAAESSK
FPSPSNGLNVSNGAVSGSSGFRSPHLWKKSIASASSRLATNEEESSSNSSKRFLRSCSAS
CVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRASENKSDVTSRGTV
TPPPRLLKQNEEGVDDVFKDTESSPGSSPPSLTPKLVRKQVTVTVSSGLSHKEETGKTSA
LGAPAALEQVPVSKAASSAFMGTSKVSSEEPRGRRHKHSSESLGKDKGKLSRLKPAPPPP
PSSSAGKSTKPSHDTAGDVGPSLKAKQLTMVADAGNSDAAKSNQLGEGVKKPALSSAPKP
PSSNKPSAAPLTTPATSPSTLPSASSVLGGEQLSSTAFVPLISTRVSLRKTRQPPERLAS
GAITKGVVLDSTEALCLAISKNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFR
EAINKLENNLRELQICPATAGSGPAATQDFSKLLNSVKEISDIVQR
NT seq
3381 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgttggagatctgtttgaagttggtgggttgcaagtcaaagaagggactttcc
tcttcctccagctgttatttggaagaagctcttcagaggccagtaactgcatctgatttt
gagccacaaggtctgagtgaagcagctcgttggaactccaaagaaaaccttcttgctggt
cccagtgaaaatgaccctaacctttttgttgcactgtatgattttgtggccagtggggat
aacactctaagtataactaaaggtgaaaagctccgtgtcttgggctataatcacaatgga
gaatggtgtgaagcacaaaccaaaaatggacaagggtgggttccaagcaactatatcacc
ccagtcaacagtttggagaaacattcctggtaccatgggcctgtatcacgaaatgctgct
gaatacctgctgagcagtggaatcaatggcagctttctggttcgagagagtgagagcagc
ccaggccagcggtccatttcactaagatatgaaggaagggtgtaccactacaggataaat
acagcatctgatggaaagctgtacgtctcttcagaaagccgctttaatactttggcagag
ttggttcatcaccattcaacggtggcagatggattgatcactactctgcattacccagct
cccaaaagaaacaaacccaccatatatggagtgtctcctaactacgataagtgggaaatt
gagcggacagacattaccatgaaacacaaacttggaggagggcagtatggagaagtgtat
gaaggtgtatggaaaaaatatagcttaactgtagctgtgaaaaccctgaaggaagatact
atggaggtggaagagttcttgaaagaagctgcagtaatgaaagagatcaaacaccctaac
ttagtacaattactaggggtttgtactcgggaacccccattttatataatcacagagttc
atgacctatgggaatctgttagattatctacgagaatgtaatcggcaggaggtgaatgca
gttgtgctactatacatggccactcagatctcatcagctatggagtacctggagaagaaa
aacttcatccacagggatcttgctgcccgaaactgccttgtaggagaaaaccacttggtg
aaggtggctgattttggcttgagcaggttaatgacaggagacacctatacagcccatgct
ggagctaagttcccaatcaaatggacagcacctgaaagcctggcttataataagttttcc
attaagtcagatgtctgggcatttggtgttttgctttgggaaattgctacatatggtatg
tccccttatcctggaattgatctgtcacaagtgtatgaattattggaaaaaaactatcgc
atggagcgtccagaaggctgtccagaaaaagtctatgaactcatgagagcatgttggcag
tggagtccttctgaccggccctcctttgctgaaatccaccaagcctttgaaacgatgttt
caggagtccagcatctcagacgaagtggaaaaagagttggggaagaaagttgtacgaagt
gttgtcagtacattactgcaggcaccagaattgccaactaagaccagaacatctaggaga
gctgctgaaaataaagacaccagcgagctgcttgacacttctcatctgaggagtcaggga
gaagatcttttggatcatgagcctgctgtttctccactgctcccaaggaaagaaagagtt
ccccaggacagtaatctgaacgaagatgaacgtcttctccccaaagacaagaaaaccaac
ctcttcagtgctcttatcaagaagaagaagaaaacagctccaaccccacccaaacgcagc
agttcttttcgggagatggatggccattcagaccgcagggcgggtggagaggatgaaacc
cgagatatcctcaatggcacttttatcacagctccctcagatgcagccgagtcatccaag
ttcccaagtccaagcaatgggttgaatgttagcaatggagcagtgtcagggtcctcaggc
ttccggtctccccacttgtggaaaaaatccattgcatcagcgagtagccgcctggcaacc
aatgaagaagaaagtagttccaactccagcaagcgtttcctgcggtcgtgctctgcctct
tgcgtaccccacggggccaaggacacagaatggaggtcagtaacactgcctcgggaccta
cagtccactggaaggcagtttgattcttctacctttggtgggcacaagagtgagaagcca
gctttgcctaggaaacgggcaagtgagaataaatctgatgtgacttctaggggcacagtg
accccgccaccccggctactgaagcaaaacgaggagggagttgacgatgtctttaaagat
acagagtccagtcctggttccagccccccaagtctgacaccaaaacttgtccgtaagcaa
gtcacagtgacagtttcctctggcttgtcccacaaagaagaaactgggaaaactagtgcc
ttaggagctcctgctgcactggaacaagtccctgttagcaaagctgcctccagtgcattt
atgggaaccagtaaggtctccagtgaagagcccagagggaggaggcacaaacattcttct
gaatcattagggaaggacaaaggaaagctttccagacttaaacctgcccctcctccccca
ccgtcatcatctgctgggaaatccaccaagccttctcatgacacagcgggggatgtagga
cctagtcttaaagcgaaacagttgactatggtagcagatgctgggaacagtgatgctgcc
aaatcaaaccagttaggagagggtgtcaaaaagccggcgctctcctctgcaccaaagccc
ccgtcatccaacaaaccatcagcggccccactaaccactccagccacctccccctctact
ttgccatctgcttcgtcagtcctgggaggggaacagctttcgtccactgctttcgtccct
ctcatatccacccgagtgtccctgcggaaaactcgccagcctccagagaggcttgctagc
ggtgctatcacaaaaggtgtggtcctagacagcaccgaggccttgtgcctggctatctcc
aaaaactcagaacagatggccagccatagtgctgtgctggaagcagggaaaaacctttac
actttctgtgtgagctacgtggactccatccagcagatgcggaacaagtttgctttcagg
gaggccatcaacaagttggaaaacaacctccgtgagcttcagatctgccccgcaacggcg
ggcagcggccctgctgccacccaggactttagcaagcttctcaactcagtgaaagaaatc
agcgatattgttcagaggtag
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integrated database retrieval system
