| Entry |
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| Symbol |
PIP5K1A
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| Name |
(RefSeq) phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
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| KO |
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| Organism |
shr Sarcophilus harrisii (Tasmanian devil)
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| Pathway |
| shr04070 | Phosphatidylinositol signaling system |
| shr04072 | Phospholipase D signaling pathway |
| shr04666 | Fc gamma R-mediated phagocytosis |
| shr04810 | Regulation of actin cytoskeleton |
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| Module |
| shr_M00130 | Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 |
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| Brite |
KEGG Orthology (KO) [BR:shr00001]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100930714 (PIP5K1A)
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
100930714 (PIP5K1A)
04072 Phospholipase D signaling pathway
100930714 (PIP5K1A)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100930714 (PIP5K1A)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100930714 (PIP5K1A)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100930714 (PIP5K1A)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
100930714 (PIP5K1A)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
100930714 (PIP5K1A)
09171 Infectious disease: bacterial
05135 Yersinia infection
100930714 (PIP5K1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:shr04131]
100930714 (PIP5K1A)
Enzymes [BR:shr01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase
100930714 (PIP5K1A)
Membrane trafficking [BR:shr04131]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100930714 (PIP5K1A)
Endocytosis
Clathrin-mediated endocytosis
LDLR adaptor proteins
100930714 (PIP5K1A)
Endosome - Golgi transport
Others
Others
100930714 (PIP5K1A)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
4:426449385..426483630
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| AA seq |
547 aa
MASSSGSTSTSLELGSSSCTSNLVPSTFKKSVTSSSEVSGSSGPVKKIGHRSVDPSGETT
YKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPGHHYND
FRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCNSGASGSLFYVSSDDEFIIKTV
QHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHV
KYDLKGSTYKRRASQKEREKVFPTYKDLDFLQDMPDGLFLDADMYNALCKTLQRDCLVLQ
SFKIMDYSLLVAIHNMEHAQRERVPTEMGSGNDTRKPAPQKALYSTAMESIQGEARRGGT
METEDQMGGIPARNNKGDRLLLYIGIIDILQSYRFMKKLEHSWKALVHDGDTVSVHRPGF
YAERFHRFMCHTVFKKIPLKLSPSKKSRIPSSLRRMGPGGNSLSPHQLTAPVSGDNKTEM
TTQVEVEPGIYFRRPDLLPRSPLVDETNSDSAATTLSTSPGSEKFNTPANSSPPSERIDA
VESEFSC |
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| NT seq |
1644 nt +upstreamnt +downstreamnt
atggcgtcgtcctccgggtcgacgtcgacctccttggagttggggagcagtagctgcacc
tccaatttagtaccgtcaactttcaaaaaatctgtgactagttcctctgaggtgtctggc
tcctctggtccagtcaagaaaattggacatagaagtgttgatccttctggggagacaaca
tataaaaagacaacctcatcagccctgaaaggtgccattcagctaggcattactcatact
gttggcagtcttagcaccaaaccagagcgggatgtcctcatgcaagacttctatgtagtg
gagagtattttcttccccagtgaagggagcaacctgacccccggccatcattataatgac
ttccgtttcaagacttatgcccctgttgctttccgctacttccgagagttgtttgggatc
cggcctgatgactacctgtattccctgtgtagtgagccactaattgagctctgcaactct
ggagccagtggctccctcttctatgtgtccagtgatgacgaattcatcatcaagactgtc
cagcacaaagaggctgagtttttgcagaagttgctgccaggatactatatgaacctgaat
cagaatccacggactctgttacccaaattctatggactgtactgtgtacaggcaggtggc
aaaaacattcgaattgtggtgatgaacaatttacttccacgttcagtcaaaatgcatgtc
aaatatgatctcaagggctcaacctacaaacggcgagcctcgcagaaagagcgagagaaa
gtgttccccacctacaaagatctggacttcttgcaagatatgcccgatggcctcttcttg
gatgctgacatgtataatgctctgtgtaaaacgctgcagcgagattgtttggtgctacag
agcttcaagatcatggactatagtctgctagtggcgattcacaacatggagcatgcacag
cgagagcgagtgcccactgaaatgggctccggcaatgatacccgaaaaccagccccacag
aaggccctctattccacagctatggagtccatccagggggaggcccggcggggtggcacc
atggaaacagaggaccagatgggtggcattcctgcccgaaacaataaaggggatcgactg
ctgctttatatcggtatcattgacatactacagtcttacaggttcatgaagaagctggaa
cattcatggaaagctctggtccatgatggggacaccgtgtcagtacacaggccgggattc
tatgctgaacgatttcatcgattcatgtgccatacagtattcaagaaaatccccttgaag
ctctctccttccaaaaaaagtcggatcccttcatcccttcgtcgaatgggtccaggtgga
aattccctctctcctcaccagctgacagcccctgtctctggagataacaagacagaaatg
acaacacaagtggaagtggaaccaggtatctacttccgccgtcctgatttactcccccga
agtccacttgtggatgagaccaatagtgactcggctgccaccaccctttctacctctcct
ggcagtgagaaattcaacacaccagctaacagttcgcctccttcagaaagaattgacgct
gtagagtcagaattcagctgttga |
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