Sarcophilus harrisii (Tasmanian devil): 100931009
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Entry
100931009 CDS
T02286
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X2
KO
K03099
son of sevenless
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr01522
Endocrine resistance
shr04010
MAPK signaling pathway
shr04012
ErbB signaling pathway
shr04014
Ras signaling pathway
shr04062
Chemokine signaling pathway
shr04068
FoxO signaling pathway
shr04072
Phospholipase D signaling pathway
shr04150
mTOR signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04510
Focal adhesion
shr04540
Gap junction
shr04630
JAK-STAT signaling pathway
shr04650
Natural killer cell mediated cytotoxicity
shr04660
T cell receptor signaling pathway
shr04662
B cell receptor signaling pathway
shr04664
Fc epsilon RI signaling pathway
shr04714
Thermogenesis
shr04722
Neurotrophin signaling pathway
shr04810
Regulation of actin cytoskeleton
shr04910
Insulin signaling pathway
shr04912
GnRH signaling pathway
shr04915
Estrogen signaling pathway
shr04917
Prolactin signaling pathway
shr04926
Relaxin signaling pathway
shr04935
Growth hormone synthesis, secretion and action
shr05034
Alcoholism
shr05160
Hepatitis C
shr05161
Hepatitis B
shr05163
Human cytomegalovirus infection
shr05165
Human papillomavirus infection
shr05200
Pathways in cancer
shr05205
Proteoglycans in cancer
shr05206
MicroRNAs in cancer
shr05207
Chemical carcinogenesis - receptor activation
shr05208
Chemical carcinogenesis - reactive oxygen species
shr05210
Colorectal cancer
shr05211
Renal cell carcinoma
shr05213
Endometrial cancer
shr05214
Glioma
shr05215
Prostate cancer
shr05220
Chronic myeloid leukemia
shr05221
Acute myeloid leukemia
shr05223
Non-small cell lung cancer
shr05224
Breast cancer
shr05225
Hepatocellular carcinoma
shr05226
Gastric cancer
shr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100931009 (SOS1)
04012 ErbB signaling pathway
100931009 (SOS1)
04014 Ras signaling pathway
100931009 (SOS1)
04630 JAK-STAT signaling pathway
100931009 (SOS1)
04068 FoxO signaling pathway
100931009 (SOS1)
04072 Phospholipase D signaling pathway
100931009 (SOS1)
04151 PI3K-Akt signaling pathway
100931009 (SOS1)
04150 mTOR signaling pathway
100931009 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100931009 (SOS1)
04540 Gap junction
100931009 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100931009 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100931009 (SOS1)
04660 T cell receptor signaling pathway
100931009 (SOS1)
04662 B cell receptor signaling pathway
100931009 (SOS1)
04664 Fc epsilon RI signaling pathway
100931009 (SOS1)
04062 Chemokine signaling pathway
100931009 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
100931009 (SOS1)
04912 GnRH signaling pathway
100931009 (SOS1)
04915 Estrogen signaling pathway
100931009 (SOS1)
04917 Prolactin signaling pathway
100931009 (SOS1)
04926 Relaxin signaling pathway
100931009 (SOS1)
04935 Growth hormone synthesis, secretion and action
100931009 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
100931009 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
100931009 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100931009 (SOS1)
05206 MicroRNAs in cancer
100931009 (SOS1)
05205 Proteoglycans in cancer
100931009 (SOS1)
05207 Chemical carcinogenesis - receptor activation
100931009 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
100931009 (SOS1)
05231 Choline metabolism in cancer
100931009 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
100931009 (SOS1)
05225 Hepatocellular carcinoma
100931009 (SOS1)
05226 Gastric cancer
100931009 (SOS1)
05214 Glioma
100931009 (SOS1)
05221 Acute myeloid leukemia
100931009 (SOS1)
05220 Chronic myeloid leukemia
100931009 (SOS1)
05211 Renal cell carcinoma
100931009 (SOS1)
05215 Prostate cancer
100931009 (SOS1)
05213 Endometrial cancer
100931009 (SOS1)
05224 Breast cancer
100931009 (SOS1)
05223 Non-small cell lung cancer
100931009 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
100931009 (SOS1)
05160 Hepatitis C
100931009 (SOS1)
05163 Human cytomegalovirus infection
100931009 (SOS1)
05165 Human papillomavirus infection
100931009 (SOS1)
09165 Substance dependence
05034 Alcoholism
100931009 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100931009 (SOS1)
01522 Endocrine resistance
100931009 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
100931009
NCBI-ProteinID:
XP_003758384
Ensembl:
ENSSHAG00000014797
UniProt:
G3WPQ9
LinkDB
All DBs
Position
2:complement(77485297..77643130)
Genome browser
AA seq
1316 aa
AA seq
DB search
MQALQLQYEFFSEENAPKWRGLLVTALKKVQMQVHPTLASNEDALQYVEELILQLLSMLC
QAQPRSVLDVEDRVQKSFPHPIDKWAIADAQSANEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKGFMAEVRQYIRELNLIIKVFREPFVSNSKLFSSH
DVENIFSRIADVHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAQ
DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSSDLYRFAEPDSEENIVFEENMQPKSGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADK
IAMENGDQPLSVELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDTDLLQRLEEFIGT
VRGKAMKKWVESITKIIQRKKMARDNGPGHNITFESSPPAVEWHISRPGHTETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
EAENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESAASAP
NSPRTPLTPPPASGASSTTDVGSVFDSEHSSPFHSRSASVSSINLTKSIDEMPIPPPVPP
RRRPESAPAESSPSKIMPKHLDSPPAIPPRQPTSKVYSPRYSDRTSISDPPESPPLLPPR
EPVRTPDVFSSSPLHLQPPPLGKKSEHGNTFFPNSPSPFTPPPPQTPSPHGTRRHLPSPP
LTQDVDLHSIPAPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq
3951 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgctgcagctccagtacgagttcttcagcgaggaaaacgcgcccaagtggagg
gggctgctggtgacggccctgaaaaaggtccagatgcaagtccatcctacacttgcttca
aatgaggatgctctccagtatgttgaagagttaattttacagttgttaagtatgctgtgc
caagctcaaccccgaagcgttttagatgttgaggatcgtgtacaaaaaagttttcctcat
ccaattgataagtgggcgatagctgatgctcaatccgctaatgaaaagaggaagcgaaga
aatccattatctctcccagtagaaaaaattcaccctttattaaaggaagttctaggatat
aaaattgaccaccaggtttctgtttacatagtggcagtattagaatacatttctgcagat
attttaaagctggttggaaattatgtacggaatatacgacattatgaaattacaaaacag
gacatcaaagtagcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagaaccttccacttcaggggaacaaacg
tactatgacttggtaaaaggattcatggctgaagttcgacaatatataagggaacttaat
ctcattattaaagtttttagagaaccatttgtctccaattcaaaattattttcttctcac
gatgtagaaaatatatttagtcgtatagcagatgttcatgaactcagtgtaaaattattg
ggccatatagaagacactgtagaaatgacagatgaaggcagtccccatccattagttggt
agctgctttgaagacttagcagaggaattggcatttgatccatatgaatcatatgctcaa
gacatattgcgacctggttttcatgatcactttcttagtcagttatccaagcctggggca
gccctctacttgcagtcaataggtgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagctcctgtgtaccactgtctacattactttgaacttttaaagcagtta
gaagagaagagtgaagaccaagaagacaaagaatgtttgaaacaagcaataacggctttg
cttaaccttcagagcagtatggaaagaatatgttccaaaagtcttgcaaaacggagattg
agcgaatctgcatgtcgattttatagccaacagatgaagggaaaacaactagcaataaag
aaaatgaatgagattcagaagaacattgatgggtgggagggaaaagacattggacagtgt
tgcaatgagtttatcatggaaggaactctcacacgtgtaggtgccaaacatgagagacac
atatttctctttgatggtctgatgatttgctgtaaatcaaatcatggtcagccaagactt
cctggtgctagcaatgctgagtatcgtctcaaagagaagttttttatgcgcaaggtacaa
atcaatgataaggatgacactaatgaatacaaacatgcctttgaaataatcttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaggagaaaaacaactggatggcagca
ctgatatcattacaatatcgtagtactctggaaaggatgctggatgtaacaatgttacaa
gaggagaaggaagagcagatgaggcttccaagttcagatctttatagatttgcagaacca
gattctgaagaaaacatagtatttgaagaaaacatgcaacccaaatctggaattccaatc
atcaaagcaggaaccgttatcaaacttatagagcgactcacctaccatatgtatgctgat
cccaattttgttcggacatttcttacaacatatagatctttctgcaagcctcaagagcta
ctgagtcttctaatagagaggtttgaaattccagagccagagccaacagaagctgataag
atagctatggagaatggagatcaacccctgagtgtggaactaaaacgatttagaaaagaa
tatatacaacccgtacaacttcgagtactaaatgtatgtcggcattgggtagaacatcac
ttctatgattttgaaagggatacagatcttttgcaacgactggaagaatttattggaaca
gtaaggggcaaagcaatgaagaaatgggttgaatctatcactaaaatcattcaacggaaa
aaaatggcaagagacaatggaccaggacataatattacatttgaaagttcaccacctgca
gttgaatggcatataagcagacctggacacacagaaacttttgatctgctcaccttgcac
ccaatagaaattgctcgacagctcactttacttgagtcagatctctacagagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaac
cttctgaaaatgattcgccacacaactaatcttactttgtggtttgaaaagtgtattgta
gaagcagaaaacctagaggaaagagtagctgtggtgagccgaataattgagattcttcaa
gtctttcaagaactgaacaactttaatggtgtacttgaggttgtcagtgccatgaattca
tcacctgtttatagactggaccacacgtttgagcaaattccaagtcgccaaaagaaaatt
ctagaggaagctcatgaactgagtgaagatcactataaaaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttgggatttatttgacaaatatcttgaaaacg
gaagaaggcaatcctgaggttttgaaaagacatggaaaagaactcataaactttagcaaa
agaagaaaagttgcagaaataacaggagagatacagcagtaccaaaatcaaccatattgt
ttgcgagtagaatctgatatcaaaagattctttgaaaatttgaatccaatgggaaatagc
atggaaaaagaattcacagattatcttttcaacaagtcactggaaattgaaccaagaaac
cctaagcctctaccgagatttccaaaaaaatatagttatcccctcaagtctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacaccccacaccactgcagcaggaacca
aggaagatcagttacagccgcatccctgaaagtgaaacagaaagtgcagcatcagcacct
aattctccacggaccccgttaacacctcctccagcttctggtgcttccagtaccactgat
gtgggcagcgtgtttgattctgagcattcaagcccttttcactcaagatctgcttcagta
tcctcaataaatttaactaagagcattgatgaaatgcccatccccccaccagtgccccca
agaagacgaccagaatccgctccagcagaatcttctccctcaaagattatgcccaaacat
ttggatagtcctccagcaattcctcctcggcaacccacatcaaaagtctattcaccacgt
tactccgaccggacctcgatctctgatcctccagaaagccctccccttttaccaccacga
gaacctgtgaggacacctgatgttttctccagctcaccactacatctccagccaccccct
ttgggcaaaaaaagtgaacatggcaatacttttttcccaaacagcccctccccctttacc
ccaccacctcctcaaacaccttctcctcacggcacaaggaggcacctaccatcaccacca
ttaacacaagatgtggaccttcattccatccctgcgcctcctgttcctccacggcaaagc
acttctcaacacatcccaaaacttcctccaaaaacttataaaagggaacacacacaccct
tccatgcatagagatggaccacctttgttggagaatgcccattcctcctga
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integrated database retrieval system
