Sarcophilus harrisii (Tasmanian devil): 100931472 Help Entry 100931472         CDS       T02286                                  Symbol OBSCN Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:shr00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100931472 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:shr01001]     100931472 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:shr04131]     100931472 (OBSCN) Enzymes [BR:shr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100931472 (OBSCN) Protein kinases [BR:shr01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    100931472 (OBSCN) Membrane trafficking [BR:shr04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     100931472 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 Ig_4 PK_Tyr_Ser-Thr Izumo-Ig Ig_6 Adeno_E3_CR1 fn3 SOS1_NGEF_PH C2-set_2 RhoGEF C2-set_3 Ig_DSCAM-DSCAML_C PH ABC1 IQ RHG20_PH Motif Other DBs NCBI-GeneID:  100931472 NCBI-ProteinID:  XP_031816003 LinkDB All DBs Position 1:complement(87843368..88167694) Genome browser AA seq 9606 aa AA seqDB search MDYTSFSGAPRFLTRPKAFLVSVGKDATLSCQIVGNPVPLVSWEKDQVPVAAGGRFRVTE EGELYRLTIVDLTLEDSGQYVCRARNSIGEAFAAVSLQVGEDSMRAELAPYFLLRPTSIR VSVGEDATFRCRLQGSPPMSVSWSKDGRRLGEPSSPDFHRVQVEARGEDSSLRIRGARPR DGGTYTVLAENPIGSASAAAALVVDEKALVGPRAAEAASGTTALLAHLQRRREEIRAEGT GLSSSLGRWSSGGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGEVVAEGRRHMIYEDE QENFVLKILFCKQTDNGLYTCTASNLVGQTYSSVLVVVREPIVPFKKKLHDLEVREKESA MFQCEVPLPATEASWYKEETILRQSHKYHIEEEGTWRRLTVQNVTTDDDAVYICEMKEGS RTIAELSVQGNITKKLPRKTMVLSGDTAIFCVELADPAEPIQWLRNQEEVKAGDRMTITS TGTCHTLTIKQCRQEDAGEVAFLAGECRTSTQFLVSAPRKPPPQAPSEPVVKAKTDSSVT LGWSPPQLDRPIGIDGYLVEKRRLGSQRWTRCHEAERVSTLEVTVSGLLEAGAYQFRVAA VNSFGQGPYLEFPGTIHLEPQLAVKTPLRAVEAIAGGEVTFTVDLTVASSGEWFLDGQAL PVSDIYVIRCKGTQHSLTISPVPANLDGAQLKFVANGIESSIRMEVKAAPVRITNKSAAV QKISARLHEEARLLAELSDQAAAVTWLKDGRALPSGPKYELQASEKRRVLRVRDVARDDA GLYECLSPGDRIAYQLSVQDLVHFLHKDVAGGYVEAVLGGQAQFECETSEAHVRVCWYKD GTELSRSQRLSQEDKGTKHRLVVGMVTRQDEGTYACRVGEDTLEFKLKVSDKAVTFINKP ASPPEVIVSPGGQLELACEVSEAGGTVVWKREQKEVRKDQRTEIHTEGTRRTLILHRVTQ NDQGTYSCHAGDDHVTFNVRVQEPSSVFSKEQQAQNKVQVVSGESVTLSCEVAQNETEVT WYKDGKKLSSSQRVHLDVKGKSRQLVVKQVGKADAGEYTCEAGGQKVTFHLSIKESVAVF AKEQQIKNKMEAVAGSSAILSCEMAQAQTEVTWYKDGKKLSSSQKVHMETKDRSRQLVVQ QVGKADAGEYTCEAGGQKVTFHLDVKESVSVFAKGQQTKNEVKAMAGSSAILSCEVAAAQ TEVTWYKNGKKLSASQKICVESKDRGRQLVVQQVGKEDSGEYTCEAGGQKVTFRLDVKEP PVVFAKEQQTQNKVEAVAGSSTTLSCELAQAQTEVTWYKDGKKLSSSQKVHVEAKGRSRQ LVVQQVGKADAGEYTCEAGGQKVTFRLDVKESVVVFAKEQKTQNKVETMAGSSTTMSCEL AQAQTEVTWYKDGKKLSPSQKVHVEAKGRSRQLVVQQAGKADAGEYTCEAGGQKVTFHLD VKESVVVFAKEQKTQSKVETVTGSSTTLSCEVAEAQTEVTWYKDGKKLSSSQKVHVESKG RSRQLVVQQAGKADAGEYICEAGGQKVTFHLDVKEPPMVFAKEQQTQSKVEAVAGSSATL SCEVAQAQTEVIWYKDGKKLSSSQKVHVEAKGLNRQLVVQQAGKADAGEYTCEAGGQKVT FRLDIKEPPVVFAKEQKTQNKVEAVAGGSATLSCELAQAQTEVTWYKDGKKLSPSQKVHV EAKGRSPQLVVQQAGKADAGEYTCEAEGQKVTFHLDVKEPPVVFAKEQKTQNKVEAMAGG SATLSCELAQAQTEVTWYKDGKKLSPSQKVHVEAKGRSRQLVVQQAGKADAGEYTCEAGG QKVTFHLDVKEPPIVFAKEQRTQSKVEAVAGSSATLSCELAQAQTEVTWYKDGKKLSPSQ KVHVEAKGRSRQLVVQQAGKADAGEYTCEAGGQKVTFHLDVKEPPVVFAKEQKTQSKVEA VAGGSATLSCELAQAQTEVIWYKDGKKLSPSQKVHVEAKGRSRQLVVQQAGKADAGEYTC EAGGQKVTFRLDVKESVVIFTKEQNMQNEVQVISGASATLSCELAQAQTEVTWYKDGKKL SPSQKVHVEAKGQRRQLVVQQVGKEDSGEYTCEAGGQKVTFRLDIKDSVAVFAKEQQTQN QVEAMAGSSATLSCEVAEAQTEVTWYKDGKKLSPSQKVHVEAKGRSRQLVVQQAERTDAG EYTCEAGGQKVTFRLDIQEPETKAPEKPARREPLVVREHEDIVLAATVSAAAAAVTWLKD GLEIRRSKRCVFSSEGTRHTLTVCGAQTQDSAVYTCRAGKEKQDFSVQVEEVPVKFARPL EPVSGAVGQTVVLSCELSHALGDVVWRCGGREIRSGKRFQLEAEGPRRSLTIVGLRAEDE GEYCCESRNDKTTARLSAVVPRMVKFTSGLINIVSEEGQEATFQCVVAPSNAVVVWSRNG VKLEPSAKYVISQSDASHSLVITALTLEDACQITAEAEGATTTASLRVREAPILFKRKLE PLTVEEKGSVLLEVELTKPCSSVKWTRNTAALVPGENVEIRAEGTRHSLLLKNVSFSDRG FFGCETPDDKTQAKLNVEMRQIRLVRGLQAIEVREQGTVTLEVELSHSDVEGNWTRDGLK LKSQDNCSITVQSVIHKLILSNLSLEDAGLIAFKAEGVHTSARLTVIELPVKFSHPLQDI VATEKEKVTLECELSRASHDVKWLKDGVVLRAGKTLGIVSQGTKRSLVIHKCEFGDQGTY VCDAGDAKTSATLQVQGRNIQIVKPLEDVEVMEKESATFTCQISHDEVQTQWYKNEGKIR PGDNIRMRQEGTTYTLLYRKVMVEDAAEIKFVAENAESRAQLRVKELPVVIVRPLRDKIA MEKHRGVLECQVSRASAQVRWFKKDVELCAGPKYEIVSDGIYRKLIINDAQPEDEDTYTC DAGDAKTSAHFFVEEQSITIVRNLKDMEVMEPAPAWFECETSIPSVRPPKWLLGKTVLQA GRDVTIEQMETVHRLTLHRTCSTMTGPVHFTIGKSKSTAQLIVSDIPVVLIRKMEDKTGR EKQSVVLSCDFKPAPKAVQWYKGDSPLEPSDKYKMKLENHMAELRILKLTPNDEGLYRCQ AGNTESSATVTVEAREVSVVQPLQDVEATEESSARFSCELSHEDEEVEWLLNGTLLYNDS FHEISHMGSCHTLVLKRVSLADTGTVSLKSAKVSQSAQLMVKEKPMVFLKPLDDMAGEEK GTLALECEVSHPKAQATWRKDGVELGPSDKYDILHTDRTRGLVVHDLSRDDAGLYTCDIG TDLTRSQVSVHDLHIGITKRLKTTEVLEGESCTLECILSHQSAGDVGTWTVDGKEVGGSG RFRASCQGRKYTLTLRNAAMTDAGEVVFTVRDLTSKASLIIKEKPASITKPLEDQRAAAG EDVSLSCELSKAGATVRWMKDGKAIRKGPRYDLRYEGSQAILVIRRASLKDSGEYTCETE VSKSKATLRVEEKPNRFTKELADVKGEEKGTAVFECETEKPASAVTWRKGIMELRATKKH APSQAGTALKLTISPLEKGDADTYTCDIGDAQSQAQLTVQGQKILITEDLEDVEVSEGSS ATFRCRISPADYSPVQWFLDKTPLHTNELNDIDVQPGGYHMLTVRQLALKDSGTIHFEAG DQRTSAALRVIEKPFEFSRELTDATVIAGETVTLCCETTIPDNPVRWTKDGKALRPSAKC QISREGCEARLVITSVREQDGGRYVCEFGKARTSSIIRIQAAPIHFKEGLKAIEVSEGGA TTLRCVLSAVAAPVEWHKGSEVIQSSSKYHLRQEGATLELIVRDLEPQDSGEYSCVFKDQ KTTATLTVKELPVRFIVDLQSAEATEGSTATLQCELSKAAPVEWKRGPKRLRASDRYSLR QDGAVCELVIHGLDVGDAGEYTCVCGEETTTAKLTVKALPAQFSEGLENTESTEGATATL RCKLSKAAPVEWRKGQKRLRASDRYSLRQDGAVCELVIQKLDVEDSGVYTCVSGEAITTA TLEVKALPAKFIEGLQSMETTEGSSSTMHCKLSKMAPVEWRKGLKKLRVSDRYNLRQDGA VCELVIFNLNIDDTGDYICVCGEEKTTMTLTVKALPTRFLKGLRSMEAAEGSTATLHCEL SKESPVEWRKGQEKLPASDRYSSRQDGVVCELVIHSLDLDDAGDYTCVCGEEKTTANLNV KAVPAQFTKGLKIMKATEGSMVTLHCELSKEAPVEWRKGPEKLQGSDRYSLKQDGVVCEL VIHRLALEDAGDYTCVCGDEKTKATLTVKALPAKFTKGLQKTEAFEGSMITLHCELSKAA LVEWRKGPEKVQASDRYIPRQDGTVCELVIHSLNLDDVGDYTCVCGDEKTKATLTVKALP AKFTKGLQKTEAIEGSMVTLGCELSKAAPVEWRKGPENLQASDRYTLKQDGIVHELVIHR LDLEDAGDYTCVCGDEKTKASLTVKALPAKFTKVLQKTEAIEGSMVTLRCELSKAAPVEW RKGPEKLQGSDRFSLKQDGIVCELVIHRLDVEDAGDYTCVCGDEKTKATLIVKALPAKFT KGLQKTEAIEGSMVTLRCELSKVAPVEWRKGPEKLQGSDRFSLKQDGIVCELVIHRLDME DAGDYTCVCGDEKTKATLTVKALPAKFTKGLQKTEAIEGSMVTLGCELSKAAPVEWRKGP ENLQASDRYTLKQDGIVHELVIHRLDLEDAGDYTCVCGDEKTTAILTVKALPSKFIEELH ITEATEGTTAILHCQLNKAASVEWRKGSQVLQDSDQYSLRQDGAVCELVIHRLDMEDSGD YTCVCGKERTTATLIVKAQKVVFRKPLKSQQAEEGETVTLRCELSKSEAPVIWSKGGLEI QTDERIQVRQKGCISELLINHLQLEDTGDYSCDCGDQTTSATLTVKALPVVFRKKLRAQD GEVGSTVRLHCELSKENASVEWRKGAVQLFPCAKYEMVLQGTVAELIIHDAEQEDTGDYT CDTGDQQATATLTVNAAKPKFKTRLHSEELEEGTTARLHCELSVSQTTVEWRKEGELLRP GSKYEMRKEGSVCELLIHGLEAKDTGEYACVAGDQKTLATVKVKEPEVTIVKGLTDMEVF ADEDVEFRCEVSREQAGNVEWKLQGLALQTNEMNEISVVGGRTHTLKLRNVTPEDTGTIS FSVGRHTSTAELLVKAPPPAFSEKLQNMEAKEASSVTLRCVLASSEAQVEWRKGGEKITP SAKYELQQQGSVHTLRIHHLTPDDEGEYTCESGKEKTTAALTIQASPALFKHELQPQVAS EGAVAILRAELSKPDAPVFWKRGSVRLQPSAKYEMRQDGVIVELIIRDLQLSDAGSYTCD SKDQQTTATLSIAAPEVTIVEPLRDVKLCEGEDAKFVCRLSRAPGQEVQWRLGGVPLQSN EMNEITAERGTLHTLTLRKVTVEDAGMVSFHVGTSSSQAQLCVTAMTPVHFQEELQDVTS TEEGTATLHCEISTPGTPVEWRKGEQVLKASAKYQIRQVGTRAELIIHTLEAEDVGAYTC IVGDKQSTATVSMQAATPVHFQEELQDVTSTEQGTAILHCKISTPGTPVEWRKGGQVLKA SAKYEIRQVGTQAELIIHTLEAEDVGAYTCIAGDKQSTATVSIQEEEFRLVHGLQNVDVF VGEAATFSCELSARGIGRARWWLDGTLLQDGPFSSISVHGGTVHTLTLRDLGPQDSGTIT FRAGSLVSSAKLLIKDPTVEVVSAMKDLTVEENSMAEFICQYSRPVRATWKINEQEVRVD GQRILVEQDWNVAKLTIKPALPCDSGVYSCEAEGTRVVALLDVQAKNTIVRGLENVEAVE GGEALFECHLAKPEVANHSWLMDDVPVRTSENIEMVYFENGRRHLLLLKNLTPQDSCRVT FLVNDMVTSAFLTVKGWRLEFLESLLDLEVKVGSKATFGCMLSETVPVNEVTWYINGTEI QPDKDWTIQVDGCRHVLLLRNAQPHHAGEVTFAARDAVSSAKLSVISLPDPPEDAEVVKQ SGRSVTLSWAAPASDGGAGLLGYRVEMKTATGEWQLCHKDLVPGTECVVSDLIPGEPYRF RIAAVGHVGAGEPVHLPQTVKLEPLEAVASASISKLVVVGEEACLECEVAGEIQEITWKK GNELIQPGGRYELISKGKKQTLVIHGFRPDDQGSYTCSSTSSKAPATASFEVAVLQSPEA EALTDGLAQPSLPPEAAQEGDLHLLWEALAKKRRMSREPTLDSISELPEEDERLQRLRRE VEEAVQDFSEGYSTPDELARTGEADLSHTSSDDESRAGTPSLVSYLKKAGKPRDKAQVPG AAAASKLGKPWQQAGAEPVVTPGLPGDLTTEILEDPSMDKAAIKIQAAFKGYKVRKEMKQ HEGPSFRDTFRDVVVEAGGSLHLECVAVSKTDMRTCWLKDGVELTDGRHYHIDSYGDGTC SLLVTGLEARDAGRYTCQVTNKFGRISHSAQVSVTGAAVTSGAESEAESSSGSEVDDAFR QAARRLHRLFRTKAASEVSDEELFFSAEEGSVELEEPSDRQTYREDDRYIYIRFETATEA RQATTRFQEMFATLGILVEINILEQGPHKVEMRIMKVAQAPASQLAYPAAPKEHPSTLLT SDTAPMFLTELQNQEVQDGYPVSFDCVVAGQPVPSVRWFKDGKVLEEDDHYMINEDQQGG HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATETSSYFSAQGY LSSREQEGAESTAEEGQLPQILEDLQDIKVAPGARLAKFHLKVKGYPMPRLYWFKDGQPL STSSRIRKTDKKTVHTLEILNVTKEDAGEYSAYIRNIVGSAYSSARLLVQGPNEPEKKID SGLHEQLVPPRFLERFTNKKVKTGSSITLSVKVEGQPPPTVNWLKEEANEDVLWIRADTP GYKVASSHLQHSLILLDIKKQHEGSYTCIATNGAGQSICSATLKVTDETDGMAKGQKKVK EALISNLLQGAGAGLVQTSETTGFNEVDRPKKGEPSETDEGRGHISLADVGTEEFLQKLT SQITEMVSAKITQATLRVPGGESDDESKTPSPSPRHGRSRPSSSVQESSSESEDGDARGE IFDIYMVTANYLPLGADPEAITLREGQYVEVLDSAHPLKWLVRTKPTKSSPSRQGWVSPA YLDKKLKLSPEWAATEVPEFPGESVSEDEYKKRLNVVIQDLLSSEQDFVSALNFLQTHHL HHLESSPSVPASVSSQKPIIFRNISDIGHFHADSFLQELKKCDTDDDVAMCFIKNEGDFE KYIQYLVGRVQAESVVVSKAVQEFYKKYSEEKLSGADPSQPPLPPLQHYLEKPIHRIQQY QTIIKELIRNKARNGQNCALLEQAYAIVSALSQRAENKLHVSLIENYPGNLEALGDPIRQ SHFIVWEGAPGARMGWKGHNRHVFLFRNHLVICKPKRDSRTDTYSYVFRNMMKLSNIDVN DQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLSLPVWNPPDFEEE LADCTAKLGETVKLACRVTGTPKPVVSWYKDGKPVDVDRHHIFIEDPDGSYALILDNLTG VDSGQYMCFAASAAGNASTLGKILVLVPPRFVNKVRTAHFVEGEDTQFTCTIEGAPYPQI RWYKNGTLLTESSKYQMFNEPRSGVLVLVIKKACKDDMGHYECELSNKLGSARSGAELFV QSTSLLTQEKRGEQAITIEDRACDGSGKLPHEDWSGPQPAPSTSKKEETAAASGPQERTI PIRMEGTTWPKSETEEAWDIHRHIYVETTQRTCIYQTGDGSITKPPSMQVTIEDIQAQAG ETTKFQAIIEGHPQPTVSWYQGSTLLTNSPRVFQEQEGTNYSLVLKDITQQDAGIYTCLA RNVGGEVLCKAELLVQGGEAEQGAERQSYRRKLHSFYEVKEEIGRGAFGFVKRVEHKGNK VSCAAKFIPLRSKTRAQAYRERDILATLNHNLVTQLLDEFETRKTLILILELCSSEELLD RLYKKNVVTENEVKVYIKQILEGLQYLHDNDILHLDIKPPNILMVHPSREDIKICDFGFA QKIIPSEPQYSKFGSPEFVSPEIIAQTPVTTTSDIWAVGVITYLSLTCTSPFAGENDRAT LLNVREGKISWIIPQAVHLSEEAKDFIKGILQLAPEARPSASKCLTHPWFMMPSVPLEEA HFINTKQLKFIVTRSRWQRSLMCYKSILVMQSIPELLQGPSDSPSLGISRHLIKEASYST SSSSSDNEIAAYSRAKSLPPSPGTYSPVLPPKSLLRSSASLPEEGEFLTGATGTPRSANQ QSGRLSPRAPQRFWGQPVLLKSASADSVTSKERGSAAIGAASSQEGDRAAAKGATCVPRQ SVIKSTFSWQACEAAEGTPPVHDYRKHLERARRNLLKGWYSKGALRGLREPLLEHYEMEQ EEARESQLGPLTKSPSFETALRLPGSTSRVSNRSHSFDDYRLRTSSPFPELSEGNEQSKE LASGDTSGAHSPAGGSPKISHSESPTIPRAPTKKQEIMAGTVSPSQAASLPTSSSQKEEV LKARPPLPKSSGSKGASTCQEGQCPPSSVPHSQMARSSPWEDGLKEGSLKSSNPFLFSDS TATFQGGNHPLVIPNLQVSPGAATEDKPTDETLKHSNPFLSSDLGPRSFPTTGSGPSAST SDEGEHKFGSLKQSNPFLYSKPGTALQEGSQLIGIPGDPLKSSNPFLYHEPGSALSGDSA AWDTTLLQKQGTPSSALPSTHREGLLKIYSSLLPGQPQPTDSPRPPAFQLQTSPSTGSVS QLRGYSASAFPGDTSPSEAIGGLTSKSEYFYSATESASLEDVVEKMVDLSKEMTVLADTV SDQQGPKAQATPRKFSYGERGGYVGIGGYGSFAFGGEGNVLGQRPLWTIRTWTESISSEE PEEVILENTLSETKSASLPEIVGTGQGAEKKIEKVAKKETGKETGKGSGEFLSWEEFGKS SQVSLVQIKDLSEDSSMGDRVSLDISEVEPAYLNLSDLYDIKYLPFEFMIFRKVPKAVEK EVPAQLEVESTERMDLEETWHKQEEFGLFPIRATGQQRSLEIMEDLDPMELMSKDTKGLI DTNRKKRKFSPTKSGFFNFSGKYQPLDNPVEHSLKKKVKASVAHISRILKGKPAFEQERR EGLEDEEAFKKKSGLSSFRLSGIKNKDRAPLFVKELTDEAVIMGQSVTLSCQVSAHPAPQ AEWFKDGVPIQTSGRLLISSTLKNFQLLTILVVTEEDLGVYKCTVSNPLGMASTTGVIRK AEIPSSPPRPDIGEIYENGVLLVWKPVESHSPVTYIIQCKIEGRDWITLASDIFDCCYYA NNLSHGGMYSFRTACVSKAGMGPYSSSSERIHIGDHQMGPAIIPDVFPGATKDKNEKVVQ TQPLSSQQTYAFQMEIRRGRFSVVRQCREKSSGRVMAAKIIPYRPEDKVATLREYEVLKA IHHPNIAQLFGAYISPRHLVLILEFCAGPELLHSLAERATYSEMEVKDYLWQILSATEFL HASHILHLDLRSENMIVTEYNLLKILDFGNAQFYTRDKVLPTEKFKDYIETMAPELLEGH GATPQTDVWAIGVTAFIMLSAEYPVSNEVTCDLQKGLRKGKIKLNRCYAGLSGGAVSFLQ STLCANPWGRPCVSSCLQCPWLTKGGLEHTQQMSVTFSTHRLKTFVKEREKKRALLYKKH NLAVLH NT seq 28821 nt NT seq  +upstreamnt  +downstreamnt atggattacacctccttcagcggggcgccccgcttcctcacccggcccaaggctttcctg gtgtccgtgggcaaagatgccaccctgagctgccagatcgtgggcaacccggtgcccctg gtgagctgggagaaggaccaggtgcccgtggcggcgggcgggcgcttccgcgtgactgag gagggggagctctatcgcctgaccatcgtggacctcaccctggaagacagcggccagtac gtgtgccgggcccgcaactccatcggcgaggccttcgccgcggtcagcctgcaggtgggc gaggacagcatgcgggcggagctggctccctacttcttgctgcggccgacctcgatccgg gtgagcgtgggagaggatgccaccttccgctgccggctccagggcagccccccgatgtca gtcagctggtccaaagacggccggcggctgggcgagccgtcgtctcccgatttccaccgc gtgcaggtggaggctcggggggaagacagctccctgaggatccggggcgcccgtccccga gacggcggcacctacacggtcttggccgagaaccccatcgggtccgccagcgccgctgct gccctcgtggtagatgagaaggccctggtggggccccgggctgcggaggccgcgtctgga acaacggccctgctggcccacctgcagaggcggagggaggagatccgggccgaaggcacc ggcttgagctccagcttggggcgctggagcagtgggggcacgcgcacgtgcaccgtgact gagggcaaacatgcacgcctgagctgctatgtgactggggagcccaaacccgagactgtc tggaagaaggatggggaggtggtcgctgagggccggaggcacatgatatatgaggatgag caggagaactttgttcttaagatactcttctgcaaacagacggacaacggactctatacg tgcacagcctccaacctggtggggcagacctatagctctgtgctggtggtggtgagagag cccattgtgcccttcaagaagaagctgcatgacctggaggtccgggagaaggagtctgcc atgttccagtgcgaggtgcccctgccggccacggaggcttcttggtataaggaggagacc atactgcggcagagccacaagtatcacatcgaggaggagggcacgtggcgccggctgact gtgcagaacgtcaccacggacgatgacgccgtgtacatctgtgagatgaaggagggcagt aggaccattgctgagctttctgtccaaggcaacatcaccaagaagctcccaaggaagacc atggtgctgagcggggacacagccatcttctgcgtggagctggcagacccggctgagccc atccaatggctgaggaaccaggaggaggtcaaggctggggaccgcatgaccatcacttcc acaggcacctgccacaccctgaccatcaaacagtgccgccaggaggacgctggggaggtc gccttcctggctggcgagtgcaggacctccacccagttccttgtgtccgctcccaggaag cctcctccacaagccccctccgaacccgtggtgaaggccaaaacagacagctctgtgaca cttggctggtccccaccacagctagatcggcctattggcattgatggctacctggtggag aagaggaggctgggcagccagcggtggactcggtgccatgaggcagagagagtctccaca ctcgaagtgactgtgagtggtctgctcgaggctggagcctatcagttccgagtggcggcc gtcaacagctttggccagggcccctaccttgagtttccaggaaccatccacctggaaccc caactggctgtcaagacaccccttcgagctgttgaagcaatagctggtggggaagtgact ttcactgtggacctcaccgtggcatcttctggtgaatggttcttggatgggcaagccctg ccagttagtgacatatatgtgattcgttgcaaaggcacccaacactccctaactatcagt cctgttcctgccaacttggatggcgctcaactcaaatttgtggccaatggcatagagagc agtatccggatggaggtcaaagccgcgccggtgcgcatcaccaacaagtctgcggccgtg cagaagatctcggcccgactgcacgaggaggcccggctcttggccgagctctcggaccag gctgcggccgtgacgtggctgaaggacggccgggccctgcccagcgggcccaagtacgag ctccaggcctccgagaagcggcgggtgctgcgggtgcgagacgtggccagggacgacgcc ggcctctacgagtgtctcagtcccggggatcgcatcgcctaccagctctccgtgcaagat ctcgtccatttcctacacaaagatgtagcaggaggctatgtggaagctgtgttggggggc caggcccagtttgaatgtgagacatcagaggcccatgtaagagtgtgttggtataaggat ggcactgaactcagtcgttcccagcgcctctcccaagaagacaagggaacaaaacaccgg ctggtggtgggcatggtcaccaggcaggatgaaggcacatatgcttgcagagttggtgaa gacacattagaattcaagctcaaggtgtctgataaagcagtgacgttcatcaacaagcca gcatcacctcccgaggtgattgtcagccctggggggcagctggagctggcctgtgaggtg tctgaggctggtggcactgtagtgtggaaaagggagcagaaagaagtgaggaaagaccag aggaccgagatccacacggaaggcactcggcggaccctcatcctgcaccgggtgacccaa aatgaccagggcacctacagttgccatgctggggatgaccacgtcactttcaacgtccgg gtacaagaaccttcatcagtattttccaaggagcagcaggcacagaataaagtgcaggtg gtgtctggggaaagcgttaccttgagctgtgaggtggctcagaacgagacagaagtgacc tggtacaaggatgggaagaaactcagctcaagccagagggttcatctggatgtcaaaggc aagagccggcagctggtggtgaagcaggtggggaaagcagatgctggagaatacacctgt gaggccgggggccagaaggtcaccttccacctcagcatcaaagaatctgtggctgtgttt gccaaggaacagcagataaagaataagatggaagctgtggccggcagcagtgccatcctg agctgcgagatggcccaggcccagacggaggtgacctggtacaaggatgggaagaaactg agctctagccagaaggtgcacatggagaccaaggaccggagtcggcagctggtggtacag caggtggggaaggctgatgctggggaatacacctgtgaggccgggggccagaaggtcacc ttccatctggatgtcaaagagagtgtgtcagtctttgccaaggggcagcagacaaagaac gaagtaaaggccatggccggcagcagtgccattctaagctgtgaggtcgccgcggctcag acagaggtgacctggtacaagaacggcaagaaattgagcgccagccagaaaatatgtgtg gaatccaaggaccggggccggcagctggtggtgcagcaggtggggaaggaggattctggg gagtacacctgtgaggctgggggccagaaggtcactttccgtctggatgtcaaagagccc ccagtggtctttgccaaggagcagcagactcagaacaaagtggaggccgtggccggcagc agcaccactttgagctgtgagctggcccaggcccagacggaggtgacctggtacaaggat gggaagaagctgagctctagccagaaggtgcacgtggaggccaagggccggagtcggcag ctggtggtgcagcaggtggggaaggcagatgctggggagtacacctgtgaggctgggggc cagaaggtcaccttccgtctggatgtcaaagaatctgtggtagtgtttgccaaggaacag aagactcagaacaaggtggagaccatggctggtagcagcactacaatgagctgtgagctg gcccaggcccagacggaggtaacctggtacaaggatgggaagaagctgagccccagccag aaggtgcatgtggaggccaagggccggagtcggcagctggtggtgcaacaggcggggaag gcagatgctggagagtacacctgtgaggccgggggccagaaggtcaccttccatctggat gtcaaagaatccgtggtggtatttgccaaagaacagaaaactcaaagcaaggtggaaaca gtgactggcagcagcaccaccctgagctgcgaggtggccgaagcccagacggaggtgacc tggtacaaggatgggaagaagctgagctccagtcagaaggtgcacgtggagtccaagggc cgaagtcggcagctggtggtgcagcaggcggggaaggctgacgctggggagtacatctgt gaggccgggggccagaaggtcaccttccatctggatgtcaaagagcccccaatggtattt gctaaggagcagcagactcagagcaaggtggaggctgtggctggtagcagcgccactctg agctgtgaggtggcccaggcccagacagaagtgatctggtacaaggatgggaagaaacta agctccagccagaaggtgcatgtggaggccaagggcctgaaccggcagctagtagtacaa caagcggggaaagctgatgctggggagtacacctgtgaggccgggggtcagaaggtcact ttccgcctggacatcaaagagcccccagtggtgtttgccaaagagcagaagacacagaac aaggtggaggccgtggctggcggcagcgccaccctgagctgcgagctggcccaggcccag acagaggtgacctggtacaaggatgggaagaagctgagccccagccagaaggtgcacgtg gaggccaagggccggagtccgcagctggtggtgcagcaggcggggaaggcagatgctggg gagtacacctgtgaggccgagggccagaaggtcaccttccacttggatgtcaaagaaccc cctgtggtgtttgccaaagagcagaagactcagaacaaggtagaggccatggccggtggc agcgccaccctgagctgtgagctggcccaggctcagacagaggtgacctggtacaaggat gggaagaagctgagccccagccagaaggtgcacgtggaggccaagggccggagtcggcag ctggtggtgcagcaggcggggaaggcagatgctggggagtacacctgtgaggccgggggc cagaaggtcaccttccatttggatgtcaaagagcccccaatcgtgtttgccaaggagcag cggactcagagtaaggtagaagctgtggctggtagcagcgccaccctaagctgtgagctg gcccaggcccagacggaggtgacctggtacaaggatgggaaaaagctgagccccagccag aaggtgcacgtggaggccaagggccggagtcggcagctggtggtgcagcaggcggggaag gcagatgctggggagtacacctgtgaggccgggggccagaaggtcaccttccacttggat gttaaagagcctccagtggtgtttgccaaggagcagaagacacagagcaaggtggaggct gtggccggtggcagcgccaccctgagctgtgagctggcccaggcccagacagaggtgatc tggtacaaggatgggaagaagctgagccccagccagaaggtgcacgtggaggccaagggc cggagtcggcagctggtggtacagcaggcgggaaaggcagatgctggggagtacacctgt gaggccggaggccagaaggtcaccttccgtctggatgtcaaagagtctgtggtgattttt accaaggaacaaaacatgcaaaatgaagtacaggtaatatctggggccagcgccaccctg agctgtgagctggcccaggcccagacagaagtgacctggtacaaggatgggaagaagctg agccccagccagaaggttcatgtggaggccaagggccagagacggcagttggtggtgcag caggtggggaaggaggattctggggagtacacctgtgaggccgggggccagaaggtcacc ttccgtttggacatcaaagattctgtggctgtctttgccaaggagcagcagactcagaac caggtggaggccatggcgggtagcagtgcgaccttgagctgcgaggtggccgaagcccag acagaggtgacctggtataaggatgggaagaagctgagccccagccagaaggtgcacgtg gaggccaagggccggagtcggcagctggtggtgcagcaggcagagaggacagatgctggg gagtacacctgtgaggctgggggccagaaggtcaccttccgtctggacatccaagaacca gaaacaaaggcccccgagaagcctgctaggcgggagccgctggtggtgcgggagcacgag gacatcgttctggcggccacggtctcggcggccgcggccgcggtcacatggctgaaggac gggctggagatccggcgcagcaagcgctgcgtgttttccagcgagggaacccgccacact ctcaccgtgtgcggcgctcagacgcaggacagtgccgtctacacctgcagagccggcaaa gagaagcaagacttttcggtgcaggtggaagaggtccctgtgaagtttgcccgacccctg gagccggtgagcggagccgtggggcagacggtggttctgtcctgcgagctgagccacgcg ctgggcgacgtggtgtggcgctgcggcggcagggagatccgttctggcaagcggttccag ctggaggccgaggggccccggcgcagcctgaccatcgtgggcctgagggctgaggacgag ggcgagtactgctgtgagagtcgcaacgacaagaccaccgcccggctcagcgccgtagtc cctcgaatggtcaagttcacatcgggcctgatcaacattgtctcggaggagggccaggag gctaccttccagtgcgtggttgcccccagcaatgctgtggtggtctggagtcggaatggt gtgaagctggagcctagtgccaaatatgtcatctctcagagcgacgccagccacagcctc gtcattaccgccctgaccctggaggatgcctgccagatcacggccgaggctgaaggggcc accacaacggccagcctcagagtccgagaggctccaattttgttcaagaggaagctggaa cccctgaccgtggaagagaaaggttcagtgttattggaagtggagctgaccaagccttgt tcttctgtgaagtggactcggaacaccgcggccttggtgcctggggagaacgtggagatc cgggccgaaggcacgcgccatagcctactgcttaagaacgtcagcttctctgaccgggga ttttttggctgcgagacgcctgatgacaagacgcaggctaagctcaatgtggagatgcgt cagatccggctagtacgaggtttgcaggccatagaggtgcgggagcagggaacagtgacc ttggaggtggaactctcacacagtgatgtggaaggcaactggacccgagatggcctgaaa ctcaagtctcaggataactgctctatcacagtccagagtgtgatccacaaattgattcta tccaacctgagcctagaggatgctggactcatagccttcaaggcagagggtgtccacaca tctgcaagactgacagtcattgagcttcctgtgaagtttagccaccccttgcaggatatt gtggctacggagaaggagaaggtcactttggagtgtgaattatcccgggccagccatgat gttaagtggttgaaggacggagtggtacttcgagcagggaagacactaggaattgtttcc caggggaccaagaggagccttgtcatccacaagtgtgagtttggagaccagggtacctat gtatgtgatgctggtgatgctaaaacttcagccacactgcaagtgcaagggaggaatata cagatcgtgaagcccctggaagatgtggaagtgatggagaaggagagtgcaactttcacc tgccagatctcccatgatgaggtacagacccaatggtacaagaatgaaggcaagatccgg cctggggataacatcaggatgcgacaggaaggaacaacctacaccttgctctaccggaaa gttatggtagaagatgctgcagagatcaaatttgtggcagagaacgcagaatctcgagcc cagctgagagtaaaagagctgccagtggtaattgtgcgaccactgagggacaaaattgcc atggagaagcaccggggagtgctggaatgccaggtgtcaagggctagtgcccaggtccga tggtttaagaaggacgtggagctctgtgctggacccaagtatgagatagtcagtgatggt atctatcggaagctgatcatcaatgatgctcaaccagaagatgaggatacatatacctgt gatgctggtgatgctaaaaccagtgcccatttctttgtggaagaacaatccattaccatt gtacggaacctgaaagacatggaagtgatggaaccggctccagcctggtttgagtgtgag acctccattccatctgttcgtccccccaagtggctgctgggcaagacagtgctgcaggct gggcgagatgtgacgattgaacaaatggagacggtccaccgcctgaccctgcaccgcacc tgctccaccatgacgggccctgtgcacttcaccattggcaaatccaagtccacagctcag ctcatcgtctcagatattcctgttgtgctgatcaggaagatggaggacaagactggccgg gagaagcaatctgtggtcctgtcttgcgattttaagcctgctcctaaggcagtgcagtgg tacaagggggacagccctcttgaaccctctgacaaatacaaaatgaagctggagaatcac atggcagagctgcggatcctgaagctcacacctaacgatgagggtctctatcggtgccag gctggtaacactgagagcagcgccacagtcactgtggaagctcgagaagtgtcagtggta cagccccttcaggatgtggaagcgaccgaggagagctctgccagattctcatgtgagctg tctcatgaggatgaggaggtggaatggctattgaatggaactctactctataacgacagc tttcatgaaatctcccacatgggaagctgccatacgttggtgcttaagcgtgtgagcctg gcagacacaggcacagtgagcctcaagtcagccaaagtatcacagtcagcccagctgatg gttaaagagaagcctatggtgttcctcaagcccctggatgacatggcaggtgaagagaag ggcactctggctctggaatgtgaagtctcccacccaaaggcccaagccacctggagaaag gacggcgtggagttgggccccagtgacaaatatgatatcctgcacactgaccgaacccgg ggtcttgtggtacatgacctttctcgagatgatgctggactgtacacctgtgacattggc actgacctgacccgctcccaagtcagtgtgcacgacctgcacattggaatcactaaacga ttaaaaaccacggaggtgctagagggagagagctgcaccttggagtgtatcctgtcccac cagagtgctggtgatgtgggcacttggacagttgatggaaaagaggtgggtggctctggc cgctttcgggcctcatgccagggtcgcaaatacaccctcaccctccgaaatgctgcgatg acagatgccggcgaggtggtgttcactgtccgtgatctcacttccaaagcctccttgatc atcaaagaaaagccagcatccatcaccaagcccctggaggaccaaagagcagcagctggg gaggacgtgagcctgagctgtgaactctccaaggccggtgccactgtgaggtggatgaag gatggcaaagccatcaggaagggtcccagatatgatctacgctatgaggggtcccaggct attcttgtcatccgcagggcctccctcaaggactctggcgagtacacatgtgagactgag gtctcaaagagcaaagccaccctcagagtggaagagaagcccaatcgcttcaccaaggag ctggccgatgtgaagggcgaggagaagggcacggcggtgtttgagtgtgagacggagaag ccagcctcggctgtgacgtggcggaagggcatcatggagctgcgtgccaccaaaaagcac gcgcccagccaagcaggcacagccctgaagctcaccatctcccctctggagaaaggggac gctgacacctatacctgcgacattggtgacgctcagtcccaggctcagcttacagtgcaa ggacaaaaaatcctcattaccgaggacctggaagatgtggaagtttctgaagggtcctca gccacatttcgatgccggatctcacctgctgactatagtcctgttcagtggtttctggat aagaccccactacacacaaatgaactcaatgacattgatgtgcagccagggggctaccac atgctgactgtgaggcagcttgccctcaaggattcggggacaatccactttgaggcaggt gaccaaaggacatctgctgccttgagagtcatagagaaaccctttgaattttcccgggag cttactgatgctacagttatcgcaggggagactgtgaccctgtgctgtgagaccacaatc ccagacaacccagtgcgctggaccaaggatgggaaggccctgcggccctcagccaagtgc cagatcagtcgcgaaggttgtgaagctcgactggttatcaccagtgtcagagaacaagat ggcgggcgctacgtgtgtgaatttggcaaggcccggaccagttccatcatcaggattcaa gctgcacccatccacttcaaagaggggctgaaagccatagaagtatctgagggaggagct accactctgcgctgtgtcctctctgcggtggctgcccccgtggagtggcacaaggggagc gaggtgatccagtcgagcagcaaatatcatctgcggcaggagggagccactctcgagctg atcgtccgggacctggagcctcaggacagcggagagtattcctgtgtcttcaaggaccag aagaccactgccaccttgactgtcaaggagctccctgtaaggttcatagttgatctgcaa agtgctgaggccacagaaggaagcacagccacacttcagtgtgagctgagcaaggcagct cctgtggagtggaagagaggtccgaagaggctccgggccagcgaccgctacagcctgaga caggatggggctgtgtgtgagctggtgatccacggcctggacgttggtgacgctggagag tatacctgtgtgtgtggagaggagacgactacagcgaagttaacagtgaaggccctgcct gcccagttctctgagggtctggagaacacagagagcacagaaggagccacagccacgctg cggtgtaagttgagtaaggcggctcctgtggagtggagaaagggtcagaagaggctccga gccagtgacagatacagcctgaggcaggatggggctgtgtgtgagctggtgatccagaag ctagatgtggaggattccggcgtctacacctgtgtgagtggagaagcaatcaccacagcg accttggaagtgaaggctctacctgccaagttcattgaaggactacagagcatggaaacc acagaaggtagctcatccacaatgcattgcaagctaagcaagatggccccagtagagtgg aggaaggggttgaagaaactccgagtcagtgacagatacaacctgagacaggatggggct gtgtgtgagctggtgatcttcaaccttaatatcgatgatactggagactacatctgtgtg tgtggagaggaaaagaccacaatgaccttgacagtgaaggctctgcccacgcggttcttg aagggtctgagaagtatggaagcagctgaaggttccacagccactctacactgtgagttg agcaaggaatctcctgtggagtggaggaaggggcaagagaagctcccagccagtgacaga tacagctcaaggcaggatggggtagtgtgtgagctggtgatccacagcttggacctggat gatgcaggagactacacctgtgtgtgtggagaggagaagaccacggcaaatctgaatgtc aaggctgtgccagctcagttcacaaaaggcctaaagataatgaaggctacagaaggctcc atggtcaccctgcactgtgagctgagcaaggaagcgcctgtggagtggaggaaggggcca gagaagctccaaggcagtgatagatacagcctgaagcaagatggtgttgtgtgtgagctg gtgatccacaggcttgctctggaggatgctggagactacacctgtgtgtgtggagacgag aagactaaggcaaccttgactgtcaaggccctgcctgccaagtttacaaaaggtctacaa aagactgaggcctttgaaggctccatgatcactctacactgtgagctgagcaaggcagcc cttgtggagtggaggaaggggccagagaaggtccaagccagtgaccgatacatcccaagg caggatgggactgtgtgtgagctggtgattcacagtcttaacctggatgatgttggagac tatacctgtgtgtgtggagatgagaagaccaaggcaaccttgactgtcaaggccctccct gccaagttcacaaaaggtctacagaaaactgaggccattgaaggctccatggtcaccctg ggctgtgagctgagcaaggcagcccctgtggagtggaggaaggggccagagaatctccaa gccagtgacagatataccctgaagcaagatggcattgtgcatgagctggtgatccacagg cttgatctggaggatgctggagattacacctgtgtgtgtggcgatgagaagaccaaggca tccttaactgtcaaggccctgcctgccaagtttacaaaagttctgcagaaaactgaggcc attgaaggctccatggtcaccctgcgctgtgagctgagcaaggcagcccctgtggagtgg aggaaggggccagagaagctccaaggcagtgacagattcagcctgaagcaggatgggatt gtgtgtgagctggtgatccacaggctggatgtagaggatgctggagattacacctgtgtg tgtggagacgagaagaccaaagcaaccttaattgtcaaggccctccctgccaagttcaca aaaggtctacagaaaactgaggccattgaaggctccatggtcaccctgcgctgtgagctg agcaaggtagcccctgtcgagtggaggaaggggccagagaagctccaaggcagtgacaga ttcagcctgaagcaggatgggattgtgtgtgagctggtgatccacaggctggacatggag gatgctggagattacacctgtgtgtgtggagacgagaagactaaggcaaccttgactgtc aaggccctccctgccaagttcacaaaaggtctacagaaaactgaggccattgaaggctcc atggtcaccctgggctgtgagctgagcaaggcagcccctgtggagtggaggaaggggcca gagaatctccaagccagtgacagatataccctgaagcaagatggcattgtgcatgagctg gtgatccacaggcttgatctggaggatgctggagattacacctgtgtgtgtggcgatgag aagaccacagcgattctgactgtgaaggccctccccagcaagttcatagaagaactccac atcactgaggccacagaagggactacagccatactacactgtcagctgaacaaggcggcc tctgtagagtggaggaaggggtcacaggtgcttcaagacagtgaccaatacagcctgagg caggatggggcagtgtgtgagctggtgatccacaggctggacatggaggatagtggagac tacacctgtgtgtgtggaaaggagagaaccacagcgactctgattgtgaaggcccagaag gttgtgttccggaaacccctgaaaagccagcaggctgaggagggtgagactgtgaccctt cggtgtgaactctctaagtctgaagccccagtgatctggagcaaaggtggtctggagatt cagactgacgagaggatccaagtacgccagaagggttgtatctctgagctgctaatcaac catctgcagctagaggacacaggtgactacagttgtgactgtggggaccagaccaccagt gctaccctgactgtcaaagccctgcctgtagtgttccgtaagaagctgcgggcccaggat ggggaggtgggctccaccgttcggctgcactgtgagctcagcaaagagaatgcaagcgtg gagtggaggaagggagccgtacagttgtttccctgcgccaaatatgagatggtgctccag ggaactgtggctgagcttatcatccatgatgctgagcaggaggacacgggtgactacacc tgtgacacgggagaccagcaggccactgctacccttacagtgaatgcggccaagcccaag ttcaagacccgcctgcatagtgaagaactggaggaaggcaccacagcccgcctgcattgt gaactgagtgtgtcccagaccactgttgagtggaggaaggagggcgagctgctccggcct ggctccaagtatgagatgaggaaggaaggcagtgtctgtgagcttctgatacatggcctg gaggccaaagacactggcgagtacgcctgtgtggctggtgatcagaagaccctggctaca gtcaaggtgaaagagcctgaagtgaccatcgtcaaaggactgacagacatggaggtattc gccgatgaggacgttgagttccgctgtgaggtatccagggagcaggcaggaaacgtggag tggaagcttcagggcctggccctgcagaccaatgagatgaatgagatctcagtggtggga ggccggacacacacactgaagctgaggaatgtcacgccagaagacacgggaactatctcc ttctctgtgggtcgccacacatcaacggctgagctccttgtcaaagctccacctcctgcc ttctctgagaagctgcagaacatggaggccaaggaagcctcctctgtcaccctccgctgt gttctggcctcttctgaggcccaggtagagtggaggaagggtggggagaagatcaccccc agtgccaagtatgagctccagcaacagggcagcgtccacaccctgaggatccaccacctc acccctgatgatgagggtgaatacacgtgtgagagtggaaaggagaagaccacagcagct ttgaccatccaagcttccccagccctcttcaagcatgaactacagccccaggtggcctca gagggagctgtggccattctgcgggctgagctctccaagcccgatgccccagtcttctgg aaacgggggtccgttcgacttcagcccagtgccaagtatgagatgaggcaagatggggtg atagtagaactgatcattcgagacctgcagctctcagacgctggcagctatacctgtgac tccaaggaccagcagacaacagccactctaagcattgcagcgcctgaggtcaccattgtc gagccccttcgggatgtgaagctgtgtgagggggaggatgccaagtttgtgtgccggctc tcgagggccccggggcaggaggtccagtggcgcctgggtggcgtgcccctccagtccaat gagatgaacgagatcaccgcagagcgtggcaccctccacacactcaccctccggaaggtg accgtggaggatgctggaatggtcagctttcacgtggggaccagcagctctcaggcccag ctctgtgtcacagcaatgacacctgtacatttccaagaagaactccaggatgtcacttca acagaggaaggcacagccaccctacattgtgaaatttccacacctggcactcctgtggaa tggaggaaaggagagcaggtcctgaaggccagtgccaagtatcagatccgccaggtgggc acccgggctgaactcatcatccacaccttggaggcagaagacgttggtgcttacacctgc atcgtgggagacaagcagagcacggccactgtctccatgcaagcagcaacacctgttcac tttcaagaagaactccaggatgtcacttcaacagagcaaggtaccgccatcctgcactgc aaaatttctacacctggcacccctgtggaatggaggaaaggagggcaggtcctgaaggcc agtgccaagtatgagatccgccaggtgggtacccaagctgaactcatcatccacaccttg gaggcagaagacgttggcgcttacacctgcatcgcgggagacaagcagagcacggccact gtctccatacaagaagaggaattccggctagtgcacggtttacagaatgtcgacgtcttt gtgggtgaggcagccaccttctcctgtgagctgtctgccaggggcatcggcagggcccgc tggtggctggatgggactctgctccaagatggtcccttcagttcaatttccgtgcacggc gggacagtccacaccttgacgctcagggacctggggccccaggactcagggaccatcacc ttccgggcggggtctcttgtatcctcagctaaattattaatcaaagatcccaccgtcgaa gtggtcagtgccatgaaggacctgaccgtcgaggagaacagcatggccgaattcatatgc cagtattcccggcctgtacgggccacgtggaagatcaatgagcaggaggtccgtgtggat gggcagcgcatccttgttgagcaggattggaatgtagccaagctaaccattaaacctgcc ctcccgtgtgacagcggcgtctattcttgtgaagcggagggcacccgcgtggtggctctg cttgatgtccaagccaagaacaccattgtccgaggcttggaaaacgtggaggcagtggaa ggaggagaagccctgtttgagtgccatttggccaagccagaggttgccaatcacagctgg ctgatggatgatgtgcctgtgagaacctcagagaacattgagatggtctactttgagaat ggccggaggcacctgctactgttaaagaacctgactccccaggacagctgtcgagtgacc ttcctagtcaatgatatggtcacatctgcttttctgactgtcaaaggctggcgtctggaa ttcctggagtctttgctcgatttggaggtcaaggttggcagcaaagccacctttggctgc atgctcagtgagacagtccctgtcaatgaggtgacctggtacatcaatggcaccgaaatt cagccagataaggactggacaatccaagttgatggctgccgccatgttttgctcctcagg aatgcccagccacaccatgctggggaggtgaccttcgcggcaagagatgctgtttcctca gccaagctgtctgtgatcagtctccctgaccctcctgaagatgctgaggttgtaaaacag agtggtcgctcagtaactttgtcatgggcagctccagcgagtgatggtggtgctggcttg cttgggtacagggtggaaatgaagacagcaacaggtgaatggcaactttgccacaaagac ttggtcccaggcaccgagtgtgtagtgagcgacctgatccctggggagccctaccgcttc cgaattgcagctgtaggtcacgtgggtgcaggagagcctgtgcacctgcctcagacggtg aagcttgagcctttagaggcagtcgcctcagcctccataagcaagttggtggtggtcggt gaggaagcttgcctggaatgtgaggtagcaggtgagatccaggaaataacctggaagaaa gggaatgaactgattcagcctgggggccgctatgagctcatctccaaaggcaagaagcaa acgctagtgatccatggtttccgacctgatgaccaaggctcctacacttgtagctccacc agtagcaaagcccctgccactgcatcttttgaagtggctgtgttgcagagcccagaggca gaagccctgaccgacggccttgcccagcccagcttgcccccagaagcagcccaggaaggt gacctgcacctgctgtgggaagctcttgccaaaaagcgccgcatgagccgggagcccact ctggactccatcagtgagctgcctgaggaggacgagcggctgcagaggctccggcgagaa gtggaggaagccgtccaggatttctccgagggctactctactcccgatgagctggcccgc actggcgaagctgacctctcacacaccagttctgatgacgagtcccgggctggcacgcca tcccttgtcagctacctcaagaaggcaggaaagcccagggacaaggcccaggtcccaggc gctgccgctgcaagcaagcttgggaaaccgtggcagcaggcgggggctgagcccgtggtc acccctgggctgcccggcgacctgactacggagatcctggaggacccatccatggacaag gctgccataaagatacaggccgcgttcaagggttacaaggtgagaaaggagatgaagcag cacgaggggcccagcttccgggacactttcagggacgtcgtggtggaggcaggaggctcc ctgcacctagagtgtgtggctgtcagcaagacggacatgaggacctgctggctcaaggat ggagtcgagctgacggatggccggcactaccacatagatagctatggggatggcacctgc tccctgctggtcactggcctggaggcccgggacgccggccgctacacctgccaggtgacc aacaagttcggccgcatctcccacagcgcccaggtgagcgtgacaggggccgccgtgacc agcggagccgagagtgaggcagagagctcatcgggcagtgaggtggacgacgctttccgc caggctgcccggagactccaccgcctgttccggaccaaggccgcctcggaagtgtccgat gaggagctgttcttcagtgcagaggagggcagcgtggagttggaggagcccagcgaccga caaacctaccgggaggatgaccgctacatctacattcggtttgagactgccactgaggcc cgccaggcgaccacccgcttccaagagatgtttgccaccctaggcatcctggtggaaatc aacatcctggagcaggggccccacaaggtggagatgcgcatcatgaaggtggcccaagcc ccagccagccagcttgcctaccctgcggctcccaaggagcacccctcgacgctgctgacc tcggacacagctcctatgttcctgacggagttacagaaccaagaggtgcaggatggctac cccgtcagctttgactgtgtggtggctggccaacctgtgcccagtgtgcgctggttcaaa gatggcaaggtgctagaagaggatgaccactacatgatcaacgaggaccagcagggtggc caccagctgatcatcacggctgtggtacctgccgacatgggtgtctaccgctgtctggct gagaacagcatgggcgtctcttctaccaaggcggaactccgtgtagacttgacaagcact gactatgacacagcagccgatgctacagagacttcttcctatttcagtgctcagggttat ctgtccagccgagaacaagaaggtgcagagtcaactgcagaagaagggcaactgccccaa attctagaggatctccaagacatcaaagtggcccctggtgcccgactggctaaattccac ctcaaggtgaaagggtacccaatgccccgcctctactggttcaaggatggtcagccctta tctacctcctcccggatccgaaagaccgataagaagacagttcacactctagaaatcctt aatgtgacaaaggaagatgccggggagtattctgcctacatcagaaacattgtgggttct gcctattcctctgcccggttgctggtccagggtcccaatgaaccagaaaagaagatagat tcaggtcttcatgaacaacttgtacctccaaggttcttggaaagatttaccaataagaaa gtaaagacgggctctagcatcaccctttcagtgaaagttgaagggcagcctcctccaaca gtgaactggctaaaggaagaagccaatgaagatgtcctctggatccgagctgacactcca ggttataaggttgctagctcccaccttcagcatagcctcatcctcctagacataaagaag caacatgagggctcttatacatgcattgccactaatggtgccggacagtccatctgctct gctactctgaaagtcacagatgagacagatgggatggccaaaggacagaagaaagtcaag gaagccctcatttcaaatctgctacagggagctggagctggcttggttcagacatcagaa accacaggttttaatgaggttgatcgaccaaagaaaggagaaccatcggaaactgatgag ggccgaggccatatttcccttgctgatgttggaactgaagaattccttcagaagttgaca tcccagattactgagatggtgtctgctaaaatcactcaggccactctccgtgttcctgga ggggagagtgatgatgaatccaagaccccttccccatctccccggcatggccggtcccga ccttcttccagtgtccaagagtcctcctctgagtctgaagatggggatgccagaggggag atctttgatatttatatggtcacagccaactacctacccctaggagcagatccagaggcc atcacattaagggaaggccagtacgtggaggtccttgattcagcccacccactcaaatgg ctggttcggaccaagccgaccaagtccagtccttcccggcaaggctgggtatcacctgct tatctggacaaaaagctcaagctttcaccagaatgggcagccactgaagtgccagagttc cctggagaatcagtctcagaggacgagtataagaagaggctaaatgtcgtcatccaagat ctgctgagctcagaacaggattttgtcagtgccctcaacttcttgcagactcaccatttg catcatctggagtccagccccagtgtacctgcctctgtgtccagccagaagcccatcatc ttccggaatataagtgacatcggccacttccatgccgatagctttctccaggagttaaag aaatgcgacactgatgacgatgtggccatgtgcttcatcaagaatgaaggagactttgaa aagtacatccagtacctggtgggccgcgtgcaggcggagtctgtggttgtcagcaaggcc gtccaggaattctacaagaaatattctgaggagaaactttcaggagcagatccttcccaa cctcctttgcctcccctgcagcattacttggagaaacccatccaccggatccagcaatat cagactattatcaaggagctgatccggaacaaggcacgaaatgggcagaactgtgccctc ctggaacaggcctatgcaattgtgtctgccctctcccagcgagccgagaacaagcttcat gtctcactcattgagaactaccctgggaatctagaggctctgggggaccctattcgccag agtcacttcatcgtgtgggagggggctcccggagccagaatgggctggaagggccacaac cggcatgtcttcctcttccggaaccacctggtgatctgcaagcccaaacgggactccagg acagacacctacagctatgtcttcagaaacatgatgaagctgagcaacatcgacgtgaac gaccaggtggaaggggatgaccgggccttcgaggtctggcacgagcgggaggactcggtt cgcaagtacctgctgcaggcgcgcactgtcatcatcaagaactcctgggtgaaggaaatc tgcggcatccagcagcggctctccttgcctgtctggaaccctccagactttgaggaagag ctagcggactgtactgccaagctgggtgagactgtcaagcttgcctgccgggtgacaggg accccaaagcctgttgtcagctggtacaaagacgggaagccagtggatgtcgatcgtcac catatcttcatagaagaccccgatggttcctacgccctcatcctggacaatctgacgggt gtggactcgggacagtacatgtgctttgctgccagtgcggctggcaatgccagcaccctg ggcaagatccttgtgctggtccctccacgatttgtgaacaaagtccgcactgcccacttt gtggagggtgaagacacacaatttacgtgtaccattgagggagctccttacccacaaata aggtggtacaagaatggcactctgttgactgagagcagcaaataccagatgttcaatgaa ccccggagtggggtgctggtactagtgatcaagaaggcttgcaaggacgacatgggacat tatgagtgtgagctatcaaacaaactaggatcagcccgcagtggagccgaactgtttgtg cagagtacttccttactgacccaggagaagagaggagaacaggctatcactattgaagat agggcatgtgatggctctggaaagctaccccatgaagactggagcggcccccagcctgcc ccaagcaccagcaagaaagaggagacggcggcagccagtggcccccaggagcgtaccatc cctattcggatggagggtacaacctggccaaagagcgagactgaggaagcctgggatatc cataggcacatctatgttgagactacacaaaggacctgcatctatcagactggagatggg agcatcacaaaacccccttctatgcaggtgaccattgaagacatacaggctcaagccgga gaaacgacaaagttccaggcaatcattgaagggcatccccagcctacagtgagctggtac cagggcagcaccttgctgaccaacagtccccgagtcttccaagaacaagaaggcaccaac tactccctggtcttgaaggacattacccagcaggacgctggcatctacacctgcttggcc aggaacgtcggtggcgaagtcttatgcaaagcagaattgctggttcaaggtggtgaagct gagcagggagcggagagacagagttaccgaaggaaactccactccttctacgaagtcaag gaagaaataggaaggggtgcttttggctttgtgaagagggttgagcacaaaggcaacaag gtatcctgtgccgcaaagttcatcccccttcggtccaagacccgggcccaggcctaccga gagcgggacatcctggccaccttgaaccataatctggtcacccagctcctagatgagttt gagaccaggaaaacactgattttgatcctggaactgtgttcctctgaagaacttctggac cgcttgtacaagaagaatgtggtgactgaaaatgaggtgaaggtatacataaagcaaatc ttagaaggcctccagtacctccatgacaatgacatcctgcacttggacattaagcctcct aatatcctaatggttcacccaagtagggaagacattaaaatctgcgattttggttttgcc caaaaaatcatcccctcggaaccccaatacagcaaatttggctcaccagagtttgtctcc ccggaaattattgcccagacccctgtgacgaccacatcagatatctgggctgttggtgtc atcacctacttaagtttgacctgcacatccccatttgctggtgagaatgaccgggcaact cttctgaatgtacgggaggggaagatttcctggatcatcccccaggctgtccacctgagc gaggaagcaaaggactttataaaggggattctccagctggcaccagaggcaagacctagt gcttccaaatgtctcactcatccatggttcatgatgccctcggttcctctggaggaagct cacttcattaacaccaagcagctgaaatttattgtgacccgaagcaggtggcagcggtct ctgatgtgctataaatccatcctggtgatgcagtcgatcccagagctcctgcagggccct tcggacagcccatcccttggcatctcccggcacctcatcaaagaggcaagctactccacc agcagctcctcctcagacaatgagatcgcagcctactctcgggccaaatccctgcctcct tctccaggaacgtattcccctgtcttgccccccaagagtcttctccgaagctccgccagc ctccctgaggagggtgaattccttacaggggccacagggaccccaagaagtgccaaccaa cagagtggcaggctgtctcctcgagctccccagaggttctgggggcagcctgtgttactg aagtcagcctctgctgacagtgtgacctccaaggaaaggggaagtgcggctataggggca gcctcatcccaagaaggagacagggcagcagccaagggagccacctgcgtgccccggcaa agtgttatcaagagcacattctcctggcaggcctgcgaggctgccgagggtacacctcct gtccatgactacaggaagcacttggagcgggcccggcggaaccttctcaagggctggtac tccaagggagcccttcggggcctgcgggagccactcctagaacattatgaaatggagcag gaggaagcccgggagtcccagctaggcccactgaccaaatcaccatcttttgagacggct ctccggctacccggctccacctcccgcgtctccaaccgaagccattcttttgatgactat aggctaagaaccagcagccccttcccagagctaagtgaggggaacgagcaaagcaaagag ctagcttctggtgatactagtggggcccactcccctgctggaggatccccaaagatcagc cactcagaaagccctaccatcccccgagcaccaaccaaaaagcaagaaatcatggcagga acagtctcaccatcacaagctgcttcattgcctacctcatcaagccaaaaagaagaagtc ctaaaggctaggccccctctgcccaaaagttcaggttcaaaaggagcaagcacttgccag gaaggtcagtgccctccctcatctgtcccacattcacagatggctcggagctcgccttgg gaggatggattaaaggagggttccttaaagagttcaaacccctttctgttcagtgattcc acagccactttccagggtggtaaccatccattggtgatccctaacttgcaagtaagccca ggagcagccactgaagacaaacccacagatgagactctgaagcactcaaacccatttctc tccagtgacctggggcccagaagtttcccaaccacaggctctggaccctctgcttccacc agtgatgagggtgagcacaagtttggatccctaaagcaatccaacccattcttatatagc aaaccaggaacagccctacaggagggcagccagctcattggaatccctggagacccccta aagagctccaatcctttcctttaccatgagcctgggtctgctctttcaggggacagtgct gcatgggatactaccctcctacaaaaacagggcactcccagttcagccttacctagcacc cacagggaagggctactgaagatatacagctccctcctcccaggccagcctcagccaaca gactcccccaggccaccagccttccaactccaaaccagcccatccacaggttcagtgagt caactccggggctattcagcatctgcttttccaggggacacttccccatcagaggctatt ggaggtttgacttccaagagcgaatatttctatagtgccacagaatcagcatccttagag gatgttgtagaaaaaatggtagatttgtccaaggagatgacagtccttgctgatacagtg tctgaccagcagggcccaaaggcacaggctacacccaggaaattttcctatggagagcgt gggggctatgtaggaattgggggctatggcagttttgcttttggtggagagggaaatgtg ctgggccaaaggcccttatggaccatcagaacctggactgaatcaatatcatctgaagaa cccgaggaggtgatactggagaacactctatctgagacaaagtctgcatccctccctgag attgtgggaactggccagggtgctgaaaaaaagattgagaaggttgcaaagaaggagaca gggaaagaaactggaaaggggtcaggggaatttctctcatgggaggaatttggcaaaagc tcccaagtctccttggtgcaaatcaaagatctttctgaagactcatccatgggagacaga gtgtctctagacatctctgaagtggaaccagcctacctaaacttgtctgatttgtatgat atcaaatacctcccctttgagtttatgattttcaggaaggtccccaaagcagttgaaaaa gaagtcccagcccaactggaagtggagagcacagagaggatggacttagaagaaacatgg cacaagcaagaagaatttggactctttcccattagagctactgggcaacagagaagtcta gagataatggaagacttggacccaatggaactcatgagtaaggacaccaagggccttata gacactaataggaagaagaggaaattctccccaaccaaatctggattcttcaatttctct gggaaataccagcctctggataacccagttgaacacagtctaaagaagaaagtgaaggct tcagtagcccatatttcaagaattctgaagggcaagccagcatttgagcaagaaaggcga gaaggcctggaggacgaagaggcttttaagaagaaatcaggattgtcatcattcagactc tctggaataaaaaacaaagatagagcacctttatttgtaaaggagctcacagatgaggct gtcatcatgggccagtccgttacactttcctgccaagtttctgctcatccagctccacag gctgaatggttcaaagatggggtccccattcagaccagtggcaggctcctcatctcctca acactcaaaaacttccagcttctaaccatactggtagtaactgaagaagacctcggagtt tacaagtgcaccgtgagcaatcccctggggatggcatccactactggagtcattagaaaa gcagaaataccttcttctcccccacggccggacattggagagatatatgaaaatggagta ctcttggtctggaagcccgtggaatcccacagtccagtgacttacatcatacaatgcaag atagaaggaagagactggatcacactggcttctgacatctttgactgctgttactatgcc aacaacctctctcatggaggaatgtactccttccgaacagcctgcgtcagcaaagcaggc atgggaccatacagcagttcctcagaacgaatccacattggtgatcatcagatgggacca gccatcatcccagatgtgttcccaggagccaccaaagacaagaatgagaaagtcgttcaa actcaacctctctcaagccagcaaacctatgcctttcaaatggaaatacggaggggtcgt ttcagtgttgtacggcaatgcagagaaaagtccagtgggcgagtcatggcagcaaaaatc atcccctatcgtcccgaagacaaagtggccacactcagagagtatgaggtgctgaaggcc atccaccaccccaatattgcacaactctttggagcctatatcagcccccgacacctggtg ctcatcttggagttctgtgctggcccagagctacttcacagcttggctgagagggcaacc tattccgagatggaagtgaaggactacctgtggcagatcctcagtgccactgagttcctc catgccagccacatcctgcatttagacctgaggtcagaaaacatgatcgtcactgagtac aacttactgaagatcctcgactttggcaatgctcagttctacacacgagacaaggtcctt cccacggagaagtttaaagactacattgaaaccatggctcctgagctcttggaggggcac ggagccaccccacagacagacgtttgggccatcggtgttactgctttcatcatgctgagc gcggagtaccctgtcagcaatgaggtgacctgtgacctgcagaagggcctgagaaaaggg aagattaagctgaaccgatgctacgctggcctgtcgggaggagcggtgtccttcctccag agcaccctgtgtgccaacccgtggggaagaccctgtgtttccagttgtcttcagtgtccc tggctgaccaaagggggcttggaacatacccagcaaatgtcagtgactttttctacccac cggctaaagacttttgtgaaggagcgggaaaagaagcgagccctgctctacaagaaacac aaccttgccgtcctccactaa

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