| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
shr Sarcophilus harrisii (Tasmanian devil)
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| Pathway |
| shr04977 | Vitamin digestion and absorption |
| shr04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:shr00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100932170 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
100932170 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
100932170 (ABCC1)
04981 Folate transport and metabolism
100932170 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100932170 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100932170 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:shr02000]
100932170 (ABCC1)
Enzymes [BR:shr01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
100932170 (ABCC1)
Transporters [BR:shr02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
100932170 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1:complement(298556026..298705338)
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| AA seq |
1524 aa
MAFPHFCSADGSDPLWDWNITWYTNNPDFTKCFQNTVLVWVPCFYLWTCFLFYFVYLCRH
DRGYIQMTYLNKAKTALGFLLWIVCWADLFYSFWERSQSIYRAPVFLVSPTLLGITMLLA
TFLIQCERKKGVQSSGVMLIFWLLTLLCAGIVFRSKVLHALRESDRVDIFRDVIFYIYFI
LVLIQLILSCFSDQSPLFSETINDPNPCPESGASFLSRITFWWITGLMVQGYKCPLEATD
LWSLNPEDTSEQVVPVLVKNWKKECAKSKKQPVKIMYSPKDPAKSKGGSKADVNEEVEAL
IVKPTQRERDPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDKQAPS
WQGYLYTALLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAIYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKEKVLEIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDDNNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRVFLSHEELEPDSIERKPIKDGGGASVTVKNATFTWSRNDLPTL
NGITFTVPEGALVAVLGQVGCGKSSLLSALLAEMDKIEGHVSIKGSVAYVPQQAWIQNAS
LRENVLFGRPLQERFYKAVIESCALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARA
VYCDSDVYLFDDPLSAVDAHVGKHIFEKVIGPQGMLKNKTRILVTHGVSYLSQVDVIIVM
SNGKISEMGSYQELLDRDGAFAEFLRTYSNTEQNVEDGGTNGPAVKEVKQMENGVLITET
SEKQLKRQISNSSSYSTEPGKHNSTADMQKSEAEKDVWKLVEADKAKTGQVKLSVYWDYM
KAIGLFISFLSIFLFICNHVAALASNYWLSLWTDDPVINGTQQHTNVRLSVYGALGISQG
ISVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPMSFFERTPSGNLVNRFSKEMDTVDSMI
PQIIKMFMGSLFNVIGACIIILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVS
RSPVYSHFNETLLGVSIIRAFEEQQRFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVG
NCIVLFAALFSVISRHSLSPGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEY
SETEKEAPWDVEEAAPPSNWPQEGRVEFRDFSLRYREDLDLVLKHINVTIEGGEKVGIVG
RTGAGKSSLTLGLFRINESADGEIIIDGINIAKIGLHHLRFKITIIPQDPVLFSGSLRMN
LDPFDQYTDEDIWTSLELAHLKNFVSALPDKLNHECTEGGENLSVGQRQLVCLARALLRK
TKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTILDYTRVIVLDKGEIVE
CGSPSVLLQKKGIFYSMAKDAGLV |
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| NT seq |
4575 nt +upstreamnt +downstreamnt
atggcgttccctcatttctgcagcgcggacggctccgatccgctctgggattggaatatc
acctggtatactaacaatccagatttcaccaagtgctttcagaacacagtgctggtatgg
gtgccttgtttttacctctggacttgcttcctattctacttcgtttatctctgtcggcac
gacagaggctatatccaaatgacatatctcaacaaagccaaaactgccttgggctttttg
ctatggatagtctgctgggcagatctattctactctttctgggaaagaagtcagagcatt
taccgggctcctgtgtttctagtcagccctacactcttgggcataacaatgttgctagct
acctttttaattcagtgcgagagaaagaaaggagtccagtcctcaggggtcatgctcatt
ttttggctcctcaccctgttatgtgctggcattgtctttcgatccaaagtactgcatgcc
ttaagagagagtgatagagttgatatatttcgcgatgtcattttctacatttacttcatc
ctggtactgattcagttgatactgtcctgcttctcagatcagtcacctctcttctcagaa
acaatcaacgatcctaatccctgtccggagtctggtgcttccttcctttctagaatcact
ttctggtggattactgggttgatggtccagggatataaatgtcctctggaggctacagat
ttatggtccctaaacccagaagacacttctgaacaggtagtgcctgttctggtgaaaaac
tggaagaaagaatgtgctaagtcaaaaaagcaacctgtaaagatcatgtattcccccaag
gatccagcaaaatcaaaagggggctccaaagcagacgtgaacgaggaggttgaagcccta
attgtgaaacccactcagagggagagggacccttctttgtttaaggtgttatataaaacc
tttgggccttacttcctcatgagcttcctttttaaagcactccatgatctaatgatgttt
gcaggccctgagatcttaaaattgctcatcaattttgtgaatgacaagcaggcccctagt
tggcaaggttatctgtatacagcacttctctttgtgagtgcctgcctacaaaccctcgtc
ctgcaccagtacttccatatctgctttgtgagtggaatgagaatcaaaactgctgttatc
ggggccatctatcgtaaggccctggtgattacaaattctgcccgaaagtcttccacagtt
ggggaaatagtgaatctcatgtctgtagatgcccagagattcatggacttggccacctac
attaacatgatctggtcagccccactgcaggtcatcctggctctctacctgctatggctg
aatttagggccttctgtgttagctggagtggctgtcatgatcctcatggttcccctcaat
gctgtgatggccatgaagaccaaaacttaccaggtggcccacatgaagagtaaagacaat
cgaatcaagttgatgaatgaaattctcaatggaatcaaagtcctgaagctgtatgcctgg
gagttggctttcaaggagaaagtgttggagatcagacaggaggagctgaaggtgcttaag
aaatctgcttatttggcagctgtggggaccttcacctgggtttgcacacccttcctggtg
gctctgtctacttttgcagtctatgtgacagtagatgataacaacatcctggatgcccag
aaagcttttgtttctctggccttattcaacattctccggtttcccttgaatattcttcca
atggtcattagcagcattgtacaggcaagtgtttccctgaaacgcctcagggtattcctt
tcccatgaagaactggagccagacagcatagagagaaagcctatcaaagatggtggtggt
gccagtgtcactgtaaaaaatgccacatttacctggtcgagaaatgatcttccgactctg
aatggcatcactttcactgtgccagagggtgccttggttgctgtgctgggccaagtgggc
tgtgggaaatcatccctgctgtctgcactcttggctgagatggacaaaatagaaggacac
gtgtctataaagggttctgtggcttacgtcccccagcaggcttggatccagaatgcttct
cttagggaaaacgtcctatttggccggccgctccaagagcggttctacaaggctgtgatt
gaatcctgtgcattactcccagacttggaaatcttgcccagtggagaccggacagagatt
ggagaaaagggtgtaaatctgtctggtggtcagaagcaacgagtgagcctggcacgggca
gtttactgtgattcagatgtgtacctctttgatgatcccctctctgcagtggatgcccat
gtgggaaaacacatatttgaaaaagtgattggccctcaggggatgctaaaaaacaagacc
cgcatattggtaactcacggggtcagctacctgtcccaggtggatgtgatcattgtgatg
agtaatggtaagatctctgagatgggctcataccaggagctgctggatcgagatggagca
tttgcagagtttctccgaacttattcgaatactgaacagaacgtggaagatggaggtacc
aatggtccagctgtgaaagaagtaaagcagatggagaatggagtgctgataactgaaaca
tcagagaagcagctaaagagacagatcagtaattcctcttcctatagcacagagcctggg
aaacacaacagcacagctgacatgcagaaatctgaagcagagaaggatgtctggaagctg
gtagaagctgataaagccaagactgggcaggtaaagctgtcagtgtactgggattatatg
aaagctattggactttttatctcttttctgagcatcttcctttttatatgtaaccatgta
gccgccttggcttccaactactggctcagcttatggactgatgatcctgtgatcaatggg
acacagcagcacacgaatgtccggctgagcgtatatggagcactgggcatttctcaaggt
atctctgtgtttggctactcaatggcagtatccattgggggcatctttgcttcccgtcgc
ctgcatctggatctcctccacaatgtcctccggtcccccatgagcttctttgaacgaaca
cccagtgggaatcttgtgaatagattctccaaggaaatggatacagtggactcaatgatt
cctcagatcatcaaaatgttcatgggatccctgttcaatgtcattggtgcctgtataatc
atattgttggccacgcccattgctgccattatcatcccaccccttgggctcatttatttc
tttgtacagaggttttatgtggcctcttcacgtcagctgaagcgcctggaatcagtcagc
cgatccccagtgtactcacacttcaatgaaactcttctgggtgtcagcatcatccgtgcc
tttgaagaacaacaacgtttcatccatcagagtgacctgaaagtggatgagaatcagaaa
gcctattaccccagcattgtggccaacaggtggctggcggtccgactagagtgtgtggga
aattgcatagttctctttgcagctttgttttctgtcatctcccggcatagcctcagccct
gggttggtgggcctctcagtctcttactcccttcaggttaccacgtacttgaactggctg
gttcgaatgtcctcagagatggaaacaaatatcgttgctgtggagaggctcaaagaatat
tcagaaacagagaaggaggctccgtgggatgttgaagaagcagcccctcccagcaactgg
ccacaggagggccgagtggaattccgagacttcagtttacgttatcgggaggacttagac
ttagttttgaaacacatcaatgttaccattgaaggaggggagaaggttggaattgtaggt
cgaactggagcaggcaagtcatcactcacactgggcttatttcgtatcaatgagtctgcg
gatggagagatcatcattgatggtatcaatattgccaagattggactgcatcacctcaga
ttcaaaatcaccattattcctcaggatccagtcttgttttctggctccctgcgcatgaac
ctggatccatttgaccagtacacagatgaagatatctggacgtctttggaactggctcac
ttgaagaacttcgtatcggctcttcccgataaactgaatcatgagtgtacagaaggaggg
gagaacctgagtgttgggcagcgccagcttgtgtgcttggcacgagctttgctgaggaaa
actaagatcttggtactggacgaagctactgctgcagtagacctggaaacagatgacctc
attcagtctacaattcgaacacaatttgatgactgtactgtcctcaccatagctcaccgg
ctcaacacaatcctggattacacaagggtgattgtcttggataaaggagaaatcgtagaa
tgtggttcaccttcggtcctcctgcagaagaagggaatcttctacagcatggcgaaagat
gcaggcttggtgtga |
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