Sarcophilus harrisii (Tasmanian devil): 100932999
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Entry
100932999 CDS
T02286
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr01522
Endocrine resistance
shr04010
MAPK signaling pathway
shr04012
ErbB signaling pathway
shr04014
Ras signaling pathway
shr04062
Chemokine signaling pathway
shr04068
FoxO signaling pathway
shr04072
Phospholipase D signaling pathway
shr04150
mTOR signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04510
Focal adhesion
shr04540
Gap junction
shr04630
JAK-STAT signaling pathway
shr04650
Natural killer cell mediated cytotoxicity
shr04660
T cell receptor signaling pathway
shr04662
B cell receptor signaling pathway
shr04664
Fc epsilon RI signaling pathway
shr04714
Thermogenesis
shr04722
Neurotrophin signaling pathway
shr04810
Regulation of actin cytoskeleton
shr04910
Insulin signaling pathway
shr04912
GnRH signaling pathway
shr04915
Estrogen signaling pathway
shr04917
Prolactin signaling pathway
shr04926
Relaxin signaling pathway
shr04935
Growth hormone synthesis, secretion and action
shr05034
Alcoholism
shr05160
Hepatitis C
shr05161
Hepatitis B
shr05163
Human cytomegalovirus infection
shr05165
Human papillomavirus infection
shr05200
Pathways in cancer
shr05205
Proteoglycans in cancer
shr05206
MicroRNAs in cancer
shr05207
Chemical carcinogenesis - receptor activation
shr05208
Chemical carcinogenesis - reactive oxygen species
shr05210
Colorectal cancer
shr05211
Renal cell carcinoma
shr05213
Endometrial cancer
shr05214
Glioma
shr05215
Prostate cancer
shr05220
Chronic myeloid leukemia
shr05221
Acute myeloid leukemia
shr05223
Non-small cell lung cancer
shr05224
Breast cancer
shr05225
Hepatocellular carcinoma
shr05226
Gastric cancer
shr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100932999 (SOS2)
04630 JAK-STAT signaling pathway
100932999 (SOS2)
04068 FoxO signaling pathway
100932999 (SOS2)
04072 Phospholipase D signaling pathway
100932999 (SOS2)
04151 PI3K-Akt signaling pathway
100932999 (SOS2)
04150 mTOR signaling pathway
100932999 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100932999 (SOS2)
04660 T cell receptor signaling pathway
100932999 (SOS2)
04662 B cell receptor signaling pathway
100932999 (SOS2)
04664 Fc epsilon RI signaling pathway
100932999 (SOS2)
04062 Chemokine signaling pathway
100932999 (SOS2)
09152 Endocrine system
04915 Estrogen signaling pathway
100932999 (SOS2)
04917 Prolactin signaling pathway
100932999 (SOS2)
04926 Relaxin signaling pathway
100932999 (SOS2)
04935 Growth hormone synthesis, secretion and action
100932999 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
100932999 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
100932999 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100932999 (SOS2)
05206 MicroRNAs in cancer
100932999 (SOS2)
05205 Proteoglycans in cancer
100932999 (SOS2)
05207 Chemical carcinogenesis - receptor activation
100932999 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
100932999 (SOS2)
05231 Choline metabolism in cancer
100932999 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
100932999 (SOS2)
05225 Hepatocellular carcinoma
100932999 (SOS2)
05226 Gastric cancer
100932999 (SOS2)
05214 Glioma
100932999 (SOS2)
05221 Acute myeloid leukemia
100932999 (SOS2)
05220 Chronic myeloid leukemia
100932999 (SOS2)
05211 Renal cell carcinoma
100932999 (SOS2)
05215 Prostate cancer
100932999 (SOS2)
05213 Endometrial cancer
100932999 (SOS2)
05224 Breast cancer
100932999 (SOS2)
05223 Non-small cell lung cancer
100932999 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
100932999 (SOS2)
05160 Hepatitis C
100932999 (SOS2)
05163 Human cytomegalovirus infection
100932999 (SOS2)
05165 Human papillomavirus infection
100932999 (SOS2)
09165 Substance dependence
05034 Alcoholism
100932999 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100932999 (SOS2)
01522 Endocrine resistance
100932999 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
PH_13
PH_19
PH_10
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
100932999
NCBI-ProteinID:
XP_031808829
Ensembl:
ENSSHAG00000003599
LinkDB
All DBs
Position
2:complement(339400228..339511651)
Genome browser
AA seq
1329 aa
AA seq
DB search
MQPPQQPYDFFSEENHPKWRGLFIPALRKVQHQVHPNLSAKEDCLYYIEELILQLLHKLC
IVQPRTVQDVEERVQKTFPHPIDKWAIADAQSAVEKRKRRTPLLLPVDKIHPLLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDESLSSGELNYYDIVRTEIAEERQYLRELNLIIKVFREAFLSNKKLFASSDI
EGIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPQFHEHFNTLMAKPAVSLHFQSIADGFKEAVQYVLPRLMLVPVYHCSHYFELLEQLQE
CSEEQEDRECLKQAITALLNFRCSMERICNKHSPRRRPVDPVCRFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIVQCCNEFIMEGPLIRIGAKHERHIFLFDGLMISCKTNHGQSRIPG
YSNAEYRLKEKFIMRKIQICDKEDTSEYKHIFELISKDENSIIFAAKSTEEKNNWMAALI
SLQYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSGIPVIKGG
TVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLKLLIERFEIPEPEPSEADKLAVE
KGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLQLLEKLESFISSVKGK
TMKKWVESIVKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQYETFDLMTLHPIEI
ARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAEN
FEERVAVLSRIMEILQVFQDLNNFSGVLEIVSAMNSVSVYRLEHTFEALQERKRKILEEA
VELSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKQGKELINFSKRRKV
AEITGEIQQYQNQPYCLRIEAEIRRFFENLNPIGNASEKEFTDYLFNKSQEIEPRNCKQP
PRFPRKTTFSLKSPGIRPHTGRHGSTSGTLRGHPTPLEREPCKISFSRINEAEHESTASA
PTSPNTPSTPPVSASSDLSVFLDTDLNTSYGSNSIFAPVILPPSKSFLNSCGSLHKLTEE
SLVPPPLPPRKKFDQDVSTSKGNVKYDDDPPAIPPRQPPPPKIKPRVPAYSGPFEGPLPS
PPPPPPRDPLPETPLPVPLRPPEHFINYPFNLQPSPMGHTHRDPDWFREASTCPNSPNTP
PSTPSPRVPHRCVLSSNQNNLAHSQAPPIPPRQNSSPHLPKLPPKTYKRDLCQPPVYRLP
LLEHAETPQ
NT seq
3990 nt
NT seq
+upstream
nt +downstream
nt
atgcagccgccgcaacagccttacgacttctttagtgaagagaaccatccgaaatggcgg
ggactcttcatccctgccctgcggaaggttcagcatcaagttcaccccaatctctcagca
aaagaggattgtctatattacattgaagagttgatccttcaactgctacataaattatgc
attgtacagccaaggactgttcaagatgtagaggaacgtgttcaaaagacttttcctcat
ccaattgacaaatgggctattgctgatgcacaatctgccgtagaaaaacgaaaacgaagg
acccctcttttgttacctgtggataaaattcatcctttattgaaggaagttttagggtat
aaagtagattatcatgtctctctttatattgtggctgtattggaatatatctctgctgat
attctgaaattggctggtaattatgtttttaatatcagacattatgaaatctcccagcag
gacattaaagtatcaatgtgtgcagataaggttttaatggacatgtttgatcaggatgac
attggtttggtttcactctgtgaagatgaatctctttcttcaggtgaactaaattactat
gacatagtcagaactgaaattgcagaagaaagacaatatctacgggaattaaatctaata
ataaaagtatttcgggaggcttttctttcaaacaaaaaactgttcgcatcttctgatatt
gaagggatattcagtaacattttagatattcatgaattgactgtaaagcttttaggcttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcctttagctggaagctgt
tttgaagatctagcagaagaacaagcatttgatccatatgaaaccttatcacaggatatt
ctttcaccacagtttcatgaacatttcaatactttgatggctaaacctgctgtttctcta
cattttcagtccattgctgatggctttaaagaggctgtacaatatgttcttccacgcctt
atgctagtgccagtttaccattgttcacactactttgaattattagagcaattgcaagaa
tgcagtgaagaacaagaagaccgagaatgtttaaaacaagctattactgctcttctgaat
ttccgatgtagcatggaacggatttgcaataagcattcacctagacggcgacctgtggat
cctgtttgtcgattttataatcgtcaattacggagtaagcacctggccattaaaaaaatg
aatgaaattcaaaaaaatattgatggatgggaaggcaaagatattgtccagtgttgtaat
gaatttataatggaaggaccattgataagaataggagctaagcatgaacgccatattttt
ctttttgatggcttaatgattagctgtaaaactaatcatggacaatcccggattccaggt
tatagcaatgcagagtacagattgaaagaaaaatttatcatgaggaaaatacaaatctgt
gataaagaagacacttctgaatacaagcatatctttgagttgatttccaaagatgaaaac
agcattatatttgctgctaagtccactgaagagaaaaataattggatggcagccttgatt
tctcttcagtatcgtagtacattagatcgaatgctagattcagtattattaaaagaagaa
aatgaacaaccattgaggttgccaagtccagaagtttatcgttttgttgtaaaagactcc
gaagaaaacattgtttttgaagacaacttgcaaagtggaatccctgtcattaaaggagga
actgtggtgaaattaattgaaagactaacctaccatatgtatgcagatcccaattttgtg
cgtacttttcttacaacctatcgttcattttgtaagccacaggaattgttgaagttattg
attgaacggtttgaaatccccgagccagaaccttccgaagcagataaattggcagtagag
aaaggagagcaaccaatcagtgcagacctgaaacggtttcgcaaagaatatgtccaacca
gtacaacttaggatactaaatgtatttcggcactgggtagaacatcatttttatgatttt
gagagagatctgcaattacttgaaaaattagaatcctttatttcaagtgtaaaagggaaa
acgatgaagaagtgggtagagtcaattgttaaaatcatcaagaggaaaaaacaagctcag
gcaaatggaattagccataatattacttttgaaagtccaccaccacccattgagtggcat
attagcagaccaggacagtatgaaacatttgatctcatgaccctgcatccaatagaaatt
gcacgtcaactaacacttctggaatctgacctctacagggcagttcagccttctgaactt
gtaggaagtgtgtggactaaagaagataaggaaataaattctccaaatttattgaaaatg
attcggcacactacaaatctaactctctggtttgaaaagtgcatagtagaagcagaaaac
tttgaagaacgagtggcagtattaagtaggattatggagattctgcaagtttttcaagac
ttgaacaatttcagtggtgtgttagagatagtcagtgcaatgaattcagtgtccgtatac
agattggaacatacatttgaagcattacaggaaagaaaacggaagattttagaagaagct
gtagaactaagccaagatcactttaaaaaatacctagcaaaactgaaatcaatcaaccca
ccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaaggtaat
aatgatttccttaaaaaacaagggaaagaattaatcaactttagtaaaagaaggaaagta
gctgaaattactggagaaattcaacagtatcagaatcagccttattgtttacggatagaa
gcagaaataaggagattctttgaaaatctcaaccctataggaaatgcatcagaaaaagaa
tttacagactatttattcaataaatcacaagaaattgaaccccgaaactgtaaacaacca
cctcgatttcctaggaaaacaactttctccttaaaatctcctggtataaggccacatact
ggcagacatggctctacttcaggcactttacgaggtcatccaactccattagaaagagaa
ccatgtaaaataagctttagtcggataaatgaggctgaacatgaatcaacagcatcagca
ccaacctctccaaacacaccatctacgccaccagtctctgcttcttcagatcttagtgta
tttttagatacagatcttaacacttcttatggaagcaacagcatctttgctccagtaatc
ttaccaccttcaaaatctttcttaaattcatgtggtagtttacataaattaactgaagag
tcactggttcctcctcctcttcctcctcgtaaaaagtttgaccaagatgtttcgacttcc
aagggaaacgtgaaatatgatgatgatcctcctgctattccaccaaggcagccaccacct
ccaaaaataaaacctcgagttcctgcttacagtggtccgtttgaagggcctttgcctagt
ccaccaccaccacctccacgagatcctcttcctgagactcctttaccagtacctcttcgg
cctcctgaacattttataaactatccatttaatcttcagccatcaccaatgggacacact
cacagagatccagattggtttcgggaagccagtacatgtccaaactcaccaaatactcct
ccaagcacaccctctccaagggtgccacatcgctgtgtgctcagttccaatcaaaataat
cttgctcattctcaagctccccctatcccaccaagacagaattcaagtcctcacttacca
aaactgccaccaaagacttacaaaagagatctttgtcaacctcctgtatatagattgccc
ttgttagaacatgcagaaactcctcagtga
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integrated database retrieval system
