Sarcophilus harrisii (Tasmanian devil): 100934668
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Entry
100934668 CDS
T02286
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 isoform X1
KO
K12385
Niemann-Pick C1 protein
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
shr04142
Lysosome
shr04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
100934668 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
100934668 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
100934668 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
shr02000
]
100934668 (NPC1)
Transporters [BR:
shr02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
100934668 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
100934668
NCBI-ProteinID:
XP_031802388
Ensembl:
ENSSHAG00000011464
UniProt:
A0A7N4UZ61
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Position
1:491464484..491513103
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AA seq
1298 aa
AA seq
DB search
MKALGPCPRLLLAVGLALLCPVQVFSQSCVWYGECGEASEGKRYNCEYSGPPKPLPKDGY
DLVQELCPGFFFGNVSLCCDTQQLQTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPR
QSQFLNVTATKSYIDPTTNETKTNVEELQYYIGQSFADAMYNACRDVESPSSNDKALGLL
CGKDAKDCNATNWIEYMFNKNNGQAPFNIIPIFSDNSLYKMEPMNNATKGCNESVDDVTG
PCSCQDCSITCGPKPQPPPPPVPWLIFGLDAMYVIMWIFYMGFLLVFFGMFFIVWCYRKR
YFVSEYTPIDGNIAFSVNASDRGMAWLLTSNLPSSPALPGEASCGDRLGAVFESCLTQGF
TRWGSFCVRNPVPVIICSLFFIAVCSSGLVFMRLATNPVDLWSAPNSQAHLEKEYFDTHF
GPFFRTEQLIIQAPHTKGHIYQPYPSGADVPFGPPLDKGILHQVLDLQTAIENITASYNN
ETVTLEDICLAPLSPYNNNCTILSVLNYFQNSHSVLDHQKGDEFFVYADYHTHFLYCTRA
PASLNDTSLLHDSCLGTFGGPIFPWLVLGGYDDQNYNNATALVITLPVNNYYNNTEKLQK
AQAWEKEFISFVKNYKNPNLTISFSAERSIEDEINRESNGDVVTVLISYAVMFLYISIAL
GHIKSFHRFLVDSKISLGIAGILMVLSSVVCSLGLFSYIGIPLTLIVIEVIPFLVLAVGV
DNIFILVQTFQRDERLQGETLDKQLGRILGEVAPSMFLSSFSETIAFFLGALSTMPAVRT
FSLFAGMAVFIDFLLQITCFVSLLGLDIKRQEKNKLDILCCVRIAEDRTDSQPSESYLFQ
FFKNAFSPFLLKDWMRPIVISVFVGILSFSIAVLNKVEIGLDQSLSMPDDSYVLDYFKSL
NQYLHAGPPVYFVLEEGHNYTSLEGQNMVCGGMGCNNNSLVQQIFNAAELENYTKIGFAP
SSWIDDYFDWIKPQSSCCRIYNMTERFCNASVVDPSCIHCRPLTPDGKRRPQGEDFMKFL
PMFLSDNPNPKCGKGGHASYSAAVHFKNNYTEIGATYFMTYHTVLHTSSDYIDAMRKARM
VAANITDTMGLQDKNYRVFPYSVFYVFYEQYLTIVDDTIFNLGVSLGAIFLVTTILLGCD
LWSSVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTK
GSRVARAEEALSHMGSCVFSGITLTKFGGIVVLAFARSQIFQIFYFRMYLAMVLLGATHG
LIFLPVLLSYIGPSVNKAKSRAAQERNRGTERERLLNF
NT seq
3897 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcgctcggtccctgcccccgactgctgctggccgtcggcctggcgctgctttgt
cccgtgcaggtattttcacagtcatgtgtttggtatggagagtgtggtgaggcatctgaa
ggcaagagatacaactgtgaatattcaggtccaccaaaaccattgccaaaggatggatat
gacttagtgcaggaactctgtccaggcttcttctttgggaatgtcagtctttgttgtgac
acacagcaacttcagacattgaaagataatttgcaactgcctctacaattcctgtccagg
tgtccatcctgtttttacaacctgatgaacctcttttgtgagctaacctgcagccctcga
caaagccagtttctgaatgttacagctaccaaaagttatattgatcccaccacaaatgag
accaaaacaaatgtagaagaactccagtactacattggacagagctttgctgatgccatg
tataatgcctgccgggatgttgagtccccctccagtaatgacaaggccctgggccttctc
tgtgggaaagatgcaaaagactgtaatgctaccaactggattgaatacatgttcaataaa
aataatggacaagcacctttcaacatcatacctattttttcagataactctctttataaa
atggaaccaatgaacaatgctaccaaaggctgtaatgagtcagtggatgatgtaactggg
ccttgtagctgtcaggattgttctattacttgtgggcccaaaccccagcccccaccacct
cctgttccttggctgatatttggcttggatgccatgtacgtcattatgtggatcttctac
atgggattcttgcttgtgttttttggaatgttttttatagtatggtgctacaggaaacgg
tattttgtctctgaatacacaccgattgatggcaatatagccttttctgttaatgccagt
gatcgaggaatggcttggctcttaacctccaacctcccttcctctcctgctcttccaggg
gaggcttcctgtggtgatcgccttggggcagtgtttgagagctgcttgacccaggggttt
acaagatgggggtctttctgcgtgagaaacccagtgcctgtcattatctgctccctgttc
ttcatcgcagtctgcagttcaggtctggtgttcatgagactcgctaccaatccagtcgat
ctttggtctgcccccaacagccaagctcacttggagaaagaatactttgacacccacttt
ggacctttcttccgtactgaacagcttataatccaggctccacacaccaaagggcacatt
taccagccatatccttccggagctgatgttccttttgggccccccctggacaaagggatt
ctgcaccaggtgctagacttgcagacggctattgagaacattactgcttcttataacaat
gaaacagtgacacttgaggacatctgtttggctcccttatctccttataacaacaactgc
actatcctgagtgtactaaattactttcagaacagccattctgttttggaccaccaaaaa
ggagacgaattctttgtctatgcagattatcacacccacttcttatactgcacaagggct
cctgcctctttgaatgatacaagtctgcttcatgattcgtgtttgggaacatttggtggg
cctattttcccttggcttgtcttaggaggctatgatgatcaaaattataataatgctact
gcccttgtgattacccttcctgtcaataattactataacaacactgaaaagctacagaaa
gcccaagcctgggaaaaagaatttatcagctttgtaaaaaactacaaaaatccaaacctg
actatttctttctctgccgaacgaagtattgaagatgagataaatcgtgaaagtaatggt
gatgttgtcactgttctaattagctatgctgtcatgtttttatatatttccatcgcctta
ggacacatcaaaagctttcatagattcctggtagattctaaaatctccctgggaattgca
ggtatcctgatggtactcagttcagtagtgtgttctctaggtctcttcagctacattgga
atacccctcaccttaattgtcattgaagtcatcccgttcttggtgcttgcagttggagta
gacaacatctttattttagttcagacctttcagagagatgaacgccttcagggggaaaca
ctagataaacaactgggcaggatcctgggggaagtggctccgagcatgttcctgtcatca
ttttcagagactatagccttcttcttaggggctttgtcaaccatgccagctgtgcgaact
ttttctctgtttgctggaatggctgttttcattgacttcctccttcaaattacttgtttt
gtgagtcttttaggcctggacattaagcgtcaggagaagaataaattggatattctgtgt
tgtgtcagaattgctgaagatagaaccgattcccagccatcagagagctatttgtttcag
tttttcaaaaatgccttctctccatttttgctgaaagactggatgcggcctattgtgata
tctgtatttgtgggtattctgtcattcagtatagcagttctcaacaaagtggaaattggc
ttggatcagtctctttcaatgccagatgactcttatgtattggattatttcaagtccctg
aaccagtacctacatgcaggtccccctgtgtattttgtgctagaagaaggacataactat
acctctttagaagggcagaacatggtgtgtggtggaatgggatgtaacaataattcactt
gtgcagcaaatttttaatgctgcagaactagagaattacacaaagataggatttgcccct
tcttcctggattgatgattattttgactggattaaaccccagtcttcctgctgccgaatt
tataatatgacagaacggttttgtaatgcttcagttgtggatccttcctgtattcattgc
cggcctttgactccagacggcaaaaggaggcctcagggtgaagatttcatgaaatttctg
cctatgtttctttctgacaaccctaatcctaaatgtggcaaaggaggccatgcatcatat
agtgctgctgttcacttcaaaaacaattataccgagatcggagccacgtactttatgact
taccacactgtgctccatacttcctctgactatattgacgccatgagaaaagcaaggatg
gtggccgctaatatcaccgacaccatgggcctccaggacaaaaactaccgggtcttcccc
tacagtgtgttttacgtcttctatgagcaatacctgactatcgtggatgacacaatcttt
aaccttggtgtatccctgggagcaatattcttggtgactacaatactcctgggctgtgac
ctgtggtcttcagtgatcatgtgtgttacaattgctatgattttggtcaatatgtttgga
gttatgtggctttggggcatcagtctgaatgccgtttccttggtcaacttggtgatgagt
tgtggtatctctgtggagttctgtagtcacataaccagagcatttactatgagcacaaag
gggagtcgggtagcacgtgctgaggaggcactgtctcacatgggcagttgtgttttcagt
ggaattacactaacaaaatttggagggattgtggtcttggcctttgccagatctcaaatt
ttccagatattttactttcggatgtatttggctatggtcttgttgggtgccacccatggc
ttaatattcctcccagtattacttagttatatagggccatcagtgaataaagctaaaagc
cgtgctgctcaagaacgaaacaggggcactgaacgagaacgactcctcaacttctag
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