Sarcophilus harrisii (Tasmanian devil): 100934974
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Entry
100934974 CDS
T02286
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100934974 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
shr03032
]
100934974 (TOP2A)
03036 Chromosome and associated proteins [BR:
shr03036
]
100934974 (TOP2A)
Enzymes [BR:
shr01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100934974 (TOP2A)
DNA replication proteins [BR:
shr03032
]
Eukaryotic type
DNA Topoisomerases
100934974 (TOP2A)
Chromosome and associated proteins [BR:
shr03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100934974 (TOP2A)
Centrosome formation proteins
Centriole proteins
100934974 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
ComGE
Motif
Other DBs
NCBI-GeneID:
100934974
NCBI-ProteinID:
XP_012403817
Ensembl:
ENSSHAG00000012147
LinkDB
All DBs
Position
4:complement(335411658..335434733)
Genome browser
AA seq
1563 aa
AA seq
DB search
MAAGMEDLSPLQPVNENLQINKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVE
VVTQQMWVYDEEVGLNYRDVTFVPGLYKIFDEILVNAADNKQRDPKMNCIKVTIDSENNT
ISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFST
RFTVETACKEYKKLFKQTWRDNMGKAGEMTLKPFSGEDYTCITFQPDLSKFKMTNLDKDI
VALMSRRAYDIAGSTKDVKVFLNGNRLPVKGFRSYVDLYVKDKLDETGNPLKIIHEEVNN
RWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIISRLIDVVKKKNKGGVAVKAHQ
VKNHMWIFVNALIENPTFDSQTKENMTLQAKSFGSKCELSEKFIKAAIGCGIVESILNWV
KFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGSKNSTDCTLILTEGDSAKTLAVSGLGV
VGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDADSLKSLRYGK
IMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHCFLEEFITPIVKVSRNKQELSFYSLPEF
EEWKNSTENHKKWKVKYYKGLGTSTSKEAKEYFSDMSRHRIQFKYSGPEDDAAISLAFSK
KQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGKATKHLTYNDFINKELILFSNSDNERSI
PSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNF
VGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDQTLKFLYDDNQR
VEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNF
KGTIDELAPNQYIISGEVSILNSTTIEISELPVRTWTQVYKEQVLEPMLNGTDKTPPLIT
DYREYHTDTTVKFIVKMTEEKLAQAEHAGLHKVFKLQTNLTCNSMVLFDHVGCLKKYDTA
LDILKDFFDLRLKYYGLRKEWLTGMLGAESARLNNQARFILEKIEGKIVIENKPKKELIK
VLIQRGYDSDPVKAWKEAQQKSPGDNEDENEESENEKETEKGDSATDSGPTFNYLLDMPL
WYLTKEKKDELCRQRTEKEQELETLKRKSPSDLWREDLAAFVEELEVVEAKEKRDEQVGA
VGKGKAGAKPKAKKGQLAEILPSPCGRRVVPRVTVEMKAEAEKKIRKKIKTENIEESSQD
DSIEPETLKQRLNKKLKTEPGTKQKKQTKLPFKPIKKENKKNPWSDSESDMSCNENDFYV
PPRETKLRRTAAANTKYTVDLDSDSDISDSKEELQDEDDDFIPSDGSSSQVKSMPKTTKG
QTTSKEEEPQKSSTLSDEVEDLEPEETKNLALASSSSSAFDFPVELEITDPVPKKSVPVK
KTATKNQSSTSTAAPKKRAAPKTSKKALASKGSPDSISEASEKIVPAKGKKPRKRKPSSS
DDSDSDFGKSISTAKSGKKSKKVDDDFEIDSNSSSMPMAPRARPGRAKKPIKYLEESDED
DMF
NT seq
4692 nt
NT seq
+upstream
nt +downstream
nt
atggccgccggcatggaggatttatcgccgctacagcctgtaaatgaaaatctacaaatt
aataaaataaagaaaaatgaagatgcaaagaaaagattgtccgtcgagaggatctatcaa
aagaaaacccagttggagcatattttactccgtcctgatacctatattggttctgtggag
gttgtgacccagcaaatgtgggtttatgatgaagaagtcggactcaactacagagatgta
acttttgttcctggtttatacaaaatttttgatgaaattttagtaaatgccgcagacaac
aagcaaagggacccaaaaatgaattgtattaaagtcacaatagattcggaaaacaataca
attagtatctggaataatgggaaaggtattcctgttgtagagcataaggttgagaaggtc
tatgtgccagctcttatctttggacagctcttgacttccagtaactatgatgatgatgag
aagaaggtcactggtggtcgaaatggatatggagccaaattatgcaatatattcagtacc
agatttacagtggaaactgcctgtaaagaatataagaaactgttcaagcagacctggagg
gataacatgggaaaagcaggtgaaatgactctcaagccctttagtggagaagattataca
tgtatcaccttccaacctgatctgtcgaaatttaaaatgacaaatctagacaaggatatt
gttgccttgatgtctagaagagcgtatgatattgctggttctaccaaagatgtcaaagtc
tttctgaatggaaataggctgcctgtaaaaggattccgtagctatgtggatttgtatgtg
aaggacaaattggatgaaactggaaacccactaaaaattatccacgaagaagtaaacaac
aggtgggaagtatgtttaactatgagtgaaaaaggcttccagcaaattagctttgtcaac
agcattgccacttccaagggtggcagacatgttgattatgtagctgatcaaattataagt
agacttattgatgttgtgaagaaaaagaacaaagggggtgttgcagtaaaagcccatcag
gtgaaaaatcatatgtggatttttgtgaatgccttaattgaaaacccaacctttgactcc
cagactaaggaaaatatgactctgcaggccaagagctttggttcaaaatgtgaattgagt
gaaaaattcatcaaagctgcaattggctgtggaattgtagaaagcatactaaattgggtg
aagtttaaggctcaagtccagttgaataaaaagtgttctgctgttaaacacaatagaatc
aaaggaattcccaaactagacgatgctaatgatgcaggcagtaagaactctacagattgt
acacttatcttgactgagggagattcagccaaaacattagctgtttctggccttggtgtg
gttgggagagacaagtatggcgttttcccccttcgaggaaaaatactcaatgtacgagaa
gcctctcataaacaaatcatggaaaatgctgaaattaacaatatcattaagattgtgggt
cttcaatacaagaaaaactatgaagatgcagattcattgaagagtctacgttatggaaaa
attatgattatgacagatcaggatcaagatggttctcacattaaaggcttgttgattaat
ttcatccatcacaattggccctctcttctgagacattgttttctggaggaatttatcact
cccattgtaaaggtttcaagaaataagcaagaattatcattttatagccttcctgaattt
gaagaatggaaaaattctactgaaaatcataaaaaatggaaagtcaagtattacaaaggt
ttgggtaccagtacatcaaaagaggctaaagaatacttttcagatatgtctagacatcga
atccaattcaaatattctggccctgaggatgatgctgcgatcagcctagcctttagcaaa
aaacagattgatgatcgaaaagaatggttaactcatttcatggaagatagaagacagagg
aaattacttggcctccctgaggattatttatatgggaaagctactaagcatctaacatat
aatgacttcataaataaagaactaatcttattctcaaactctgataatgagaggtccatt
ccatcaatggtagatggtctgaaaccaggtcagagaaaagtcctgttcacatgtttcaaa
agaaatgataaaagagaagtaaaggttgcccagttagctggttcagtagctgagatgtcc
tcttatcatcatggtgaaatgtcattaatgatgaccattattaatttggctcaaaatttt
gtgggcagcaacaatctcaacctcttgcaacccattggtcagtttggtaccaggctgcat
ggtggcaaggactctgctagccctcgatacatcttcacaatgctcagcccattggctcgg
ttgcttttcccagcaaaggatgatcagactttgaagttcttatatgatgataaccaacgt
gtagagccagaatggtacattcctattattcccatggtgttgataaatggtgcagaaggt
atcggaactgggtggtcatgtaagattcccaactttgatgtccgagaagttgtgaataac
atcaggcgtctaatggatggagaagaacctttaccaatgctccccagttacaaaaatttc
aaaggtacaattgatgagctggctccaaatcaatatattatcagtggtgaagtgtctatt
ctaaattctacaactattgaaatctctgagcttcctgtcagaacttggacccaggtatat
aaagagcaggttctggagcccatgttgaatggcaccgacaagacaccccctctcataaca
gactacagagaataccacactgatactacagtgaagttcatagtgaagatgactgaagaa
aaactggcccaagcagagcatgcaggactgcataaagtcttcaaacttcagactaatcta
acatgtaattccatggtactttttgatcatgttggttgtctaaagaaatatgatactgca
ttggatatcctaaaagacttctttgatctgaggcttaaatattatggactgagaaaagaa
tggcttactggaatgcttggtgctgaatctgccagattgaacaaccaggctcggttcatc
ctagagaagatagaggggaaaattgtcattgaaaataaacctaagaaagaattaattaag
gttctgatccagagaggatatgattcagatcctgtcaaggcctggaaggaagctcagcaa
aagagtccaggagacaatgaagatgaaaatgaagaaagtgaaaatgaaaaagaaactgaa
aaaggtgattctgccactgattctggaccaacttttaattaccttcttgatatgcctctc
tggtatttgaccaaagagaagaaagatgaactctgcaggcagaggactgaaaaagagcaa
gaactggagaccttaaaacgaaaaagtccttcagatttgtggagagaagatctggctgct
tttgttgaagaacttgaggttgttgaagccaaggaaaaacgcgatgaacaagtgggtgct
gttggtaaaggtaaagctggtgcgaaaccaaaggcaaagaagggtcaactagcagaaatt
ttgccttctccttgtggtagacgagtcgtccctagagtgactgtagaaatgaaagcagaa
gcagaaaagaaaatcagaaagaaaattaagactgaaaatattgaagaaagttctcaagac
gacagtatcgaaccagaaactctgaaacaaagactaaacaaaaaacttaagacagaacca
ggtaccaaacaaaagaaacagaccaaattgccattcaaaccaatcaaaaaggaaaataag
aaaaatccttggtctgattcagaatctgatatgagttgtaatgaaaatgacttttatgtc
ccccctagagaaactaaattacgaaggacagcagcagcaaataccaaatacacagttgat
ttagattcagacagcgatatttcagattctaaagaggaacttcaagatgaagatgatgat
tttattccatcagatggaagttcatctcaagttaaaagtatgccaaaaacaactaaagga
caaactactagcaaagaagaggagccacagaaaagtagtaccttatcagatgaggtggag
gacttggaacctgaagagactaagaacttggctctggcctcttcaagctcttctgctttc
gattttccagttgaacttgaaattacagatccagtccccaaaaaaagtgtcccagtgaaa
aagactgcaaccaagaatcagtcttccacgtctacagctgcaccaaagaaaagggcagca
ccaaaaacaagcaaaaaggcccttgcatccaaagggtctccagactccatctcagaagcc
tctgaaaagatagtaccagccaaaggcaagaaacctcgcaaaaggaagccttctagctct
gacgactctgattcagattttgggaaaagcatatcaacagcaaagtcagggaagaaatcc
aagaaggtggacgatgacttcgagattgactcaaattcaagctcgatgcctatggcacct
cgggcaagacctggccgagcaaagaagcctattaaatacctagaagaatcagatgaagat
gatatgttttaa
DBGET
integrated database retrieval system
