Sarcophilus harrisii (Tasmanian devil): 100935398
Help
Entry
100935398 CDS
T02286
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04140
Autophagy - animal
shr04141
Protein processing in endoplasmic reticulum
shr04210
Apoptosis
shr04932
Non-alcoholic fatty liver disease
shr05010
Alzheimer disease
shr05012
Parkinson disease
shr05014
Amyotrophic lateral sclerosis
shr05016
Huntington disease
shr05017
Spinocerebellar ataxia
shr05022
Pathways of neurodegeneration - multiple diseases
shr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100935398 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100935398 (ERN1)
09143 Cell growth and death
04210 Apoptosis
100935398 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100935398 (ERN1)
05012 Parkinson disease
100935398 (ERN1)
05014 Amyotrophic lateral sclerosis
100935398 (ERN1)
05016 Huntington disease
100935398 (ERN1)
05017 Spinocerebellar ataxia
100935398 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
100935398 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100935398 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100935398 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100935398 (ERN1)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100935398 (ERN1)
Protein kinases [BR:
shr01001
]
Serine/threonine kinases: Other
IRE family
100935398 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
100935398
NCBI-ProteinID:
XP_031821739
Ensembl:
ENSSHAG00000014118
UniProt:
G3WME2
LinkDB
All DBs
Position
4:322872464..323006081
Genome browser
AA seq
980 aa
AA seq
DB search
MPVPLRRLLQLLALLLLPLPGPGSFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSTKWT
LKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGI
LYMGKKQDIWYVVDLMTGEKQQTLSSAFAESLCPSTSLLYLGRTEYTITMYDTKNRELRW
NATYFDYAANVPEEDMEYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWHRE
GLQKVMHTNVGVETLRYLTFMSGEVGRITKWKYPFPKETETKSKLTPTLYVGRYSTSLYA
SPSMVHEGVAIVPRGSAFPQLEGPQTDGVTIKNNEECVITPSIDLNIDFGIKGKNKLNYW
TNYWLLIGHHEIPLSASTTVLEKFPNKLPRHRENVIHADSEKSFEEKVIKIVDRDTEEPT
PATHQDIEFTRTPVKTEAAVDSILKDMATIILCTFLLIGWVAFVITYPMSMHQQQQLQHQ
QFQRQLEERIQLLQQQQLPFQTPGDLAQDSDFLDTSAGLHSESSAPSSPNMSPKGSNHSQ
HSSNSASKVSGSITTEQDEDDEETSMVVVGKISFCPKDVLGHGAEGTIVYRGMFDNRAVA
VKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKD
FAHLGLEPITLLQQTTSGLAYLHSLNIVHRDLKPHNILLSMPNAHGKIKAMISDFGLCKK
LAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISDGNHPFGK
SLQRQANILLGAYSLNCLHPEKHEDIVAHELIEKMIAMDPQKRPSAKHVLKHPFFWGLEK
QLQFFQDVSDRIEKEALDGPIVKQLERGGRMVVKMDWRENITVPLQTDLRKFRTYKGGSV
RDLLRAMRNKKHHYRELPEDVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCSHERLF
QPYYFQEATELDPPVTNDGL
NT seq
2943 nt
NT seq
+upstream
nt +downstream
nt
atgccggtcccgctgcgccggctcctgcagctgctggcgctgctgctcttacccctgccg
ggtcccgggagttttggaagtaccagcactgtgacccttcctgagactctgttgtttgtt
tcaactctggatggaagtctgcatgctgtgagcaagaggacaggctcaaccaaatggact
ttaaaagaagatccagtcctgcaagttcccacccacgttgaagagcctgcattccttcca
gaccccaatgatggaagcttgtatacacttggtggtaaaaacaatgaaggtctgacgaaa
cttccctttaccatcccagaattggtgcaggcatccccatgccgaagttcagatgggatt
ctctatatgggtaagaagcaggacatttggtacgttgttgaccttatgactggagagaag
cagcagactttgtcttcagcatttgcagaaagcctctgtccatccacctctcttctgtat
cttggacgcacagagtacaccatcaccatgtatgatacgaagaaccgagagcttcggtgg
aatgctacctattttgattatgcggctaatgtaccagaagaagacatggagtacaagatg
tcccactttgtgtccaatggggacgggctggtggtgaccgtggacagtgaatctggagat
gtcctgtggattcagaattacgcctcgccggtggtggccttctacatctggcatcgggaa
ggcctgcagaaggtgatgcacaccaacgttggggtggagacgctgcgctatctgaccttc
atgtctggagaggtggggcgtatcaccaagtggaaataccccttcccaaaggagaccgag
accaagagcaaattgacgcccaccctctatgttgggagatattccaccagcctgtacgcc
tccccatccatggtccatgaaggagtcgccattgtgcctcgaggcagtgcctttccccaa
ctggaaggcccccagacagatggtgtcacgatcaaaaataatgaagaatgtgtgattacc
cccagcatagacctgaacattgattttggaatcaaaggaaagaataaactcaactattgg
accaattattggcttctcattggacatcatgagatcccactatctgcttctaccacagtc
ttggaaaaattccccaataaactgcccagacatcgtgaaaatgtgatccatgctgattca
gagaagagttttgaggagaaggttatcaaaatagttgaccgggacacagaagaaccaact
cctgctactcatcaagatattgaattcactcgaaccccagtaaaaacagaggcagctgtg
gactccattttgaaggacatggctacaatcatcctgtgtacctttcttcttattggatgg
gtcgcctttgtcatcacgtacccaatgagcatgcaccagcaacagcaactccagcaccag
caatttcagaggcaactggaagagaggatccagctgctacaacaacagcagcttcctttc
caaactcctggtgacctggctcaggactcggatttcctggatacttctgctggtttgcac
tcagagagctcagctcccagcagccccaacatgtccccgaagggctccaaccactctcag
cattccagcaattcggcttccaaggttagcggcagcatcaccactgagcaagatgaggac
gatgaagagaccagcatggttgtggttgggaaaatttccttttgcccaaaggatgtcttg
ggacatggagctgaaggcacaatcgtatatcgggggatgtttgacaatcgagctgtggca
gtgaagaggatactcccagagtgcttcagttttgcagaccgtgaggtgcagctgcttcgg
gaatccgacgagcaccccaatgtgattcgttatttctgcacggagcgggaccgtcagttc
caatatattgccattgaactgtgtgcagccactttgcaagagtacgtggaacagaaggac
tttgctcaccttggcttagaacccatcaccttgttgcagcagacaacatcgggacttgct
taccttcattccctcaacattgttcacagagacctgaaaccccataacatcctcctttct
atgcccaatgcacacggtaagatcaaagctatgatctctgactttggtctctgcaagaag
ctggcagtaggaaggcacagtttcagtcgccgctctggagtaccaggcactgagggatgg
attgctccagagatgctgagtgaagattgcaaagagaatccaacttatacagtggacatc
ttctctgcgggctgtgtcttttactatgtgatatctgacggcaatcacccatttggcaag
tccctgcagcggcaagccaatattctccttggtgcctacagccttaactgtttgcaccca
gagaagcatgaagacatcgttgctcatgaactaatagaaaaaatgattgctatggatccc
cagaaacgaccctcagccaagcacgtgctgaaacacccattcttctggggcttagaaaag
cagctacaattctttcaggacgtgagtgaccggatagagaaggaggccttagatggtccc
atagtgaaacaactagaaagaggagggagaatggtagtcaaaatggactggagggaaaac
ataactgttccactccagacagatcttcgaaaattcagaacctataaagggggttctgta
agagatcttcttcgtgcaatgagaaataagaaacaccactaccgagaactccccgaagat
gtacaggaaacattgggctcaatccctgatgattttgtccgttatttcacatcacggttc
ccccacctcctttcccacacctaccgagccatggaactgtgtagccatgagagactcttc
cagccttactatttccaagaggccacagaactggaccccccagtgacaaatgatggcctc
tga
DBGET
integrated database retrieval system
