Schistosoma haematobium (urinary blood fluke): MS3_00008704
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Entry
MS3_00008704 CDS
T05004
Symbol
DOT1L_1
Name
(RefSeq) Histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
shx
Schistosoma haematobium (urinary blood fluke)
Pathway
shx00310
Lysine degradation
shx01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
shx00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
MS3_00008704 (DOT1L_1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
shx03036
]
MS3_00008704 (DOT1L_1)
Enzymes [BR:
shx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
MS3_00008704 (DOT1L_1)
Chromosome and associated proteins [BR:
shx03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
MS3_00008704 (DOT1L_1)
HMT complexes
Dot1-containing complex
MS3_00008704 (DOT1L_1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
NpmA
DUF2333
Motif
Other DBs
NCBI-GeneID:
24596715
NCBI-ProteinID:
XP_051065680
UniProt:
A0A922IKP3
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All DBs
Position
6:18836198..18885851
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AA seq
1333 aa
AA seq
DB search
MSENPTLVELLKETDRSSYDDVSKLCDVYNKAIIDLWDMWIEENTVPEFFNRKASRGHVQ
FILLQCYNRAVSDPDKLNQYPPFSPQVYGETSFELISQMIDTIAVTSDDVFIDLGSGVGQ
VVLQVCASTDAKFCYGIEKAEYPANCASRLDSTFRHWMSFYGKSYRPYTLERGDFLSAEY
QEKITNAGVLFANNFAFGPEVDHQLKQRFANLKEGARIISSKAFCPLNFRITDRNLGDIG
SIMRVSCLNPIQDAVSWTDKPFSYYVHTIDRSLLEQYFARLKNPKSKNENRTVRRDRKGR
VISEATMREGSIQLTLNASGNNQHNTNGNVSHKAKRSSAIIKHRSSTSRCLPNRSASLPA
VTASSPSELISVKGRKLSSQNYLSKNETISRQITNGSMVVHRIKQCESPHLQSELKRSHV
HHKDNQSPLDIFTLSKDTSNAGLVESHVDTQLASLTSGGPIACDNNEDRKQFRKVIQHLL
DDPCESHSLSKSDNIKQSVRRKSKTIENDNKLTFNYPIIDDYLSLHSSSCHDQRDSRNSS
SSPYVSSLSSANRSPNSQIDEITSLNSLTKRSDLELKSVQSPDLSIFPENKLDKDKHEDS
FHIRIKFKISNSPCGQNHPVSVKIKPPCNGDNTPNRLSNPENSNDTCDTNVINKDHPNSV
ANRRILRKCRQMLSDDSSSLNVTNFKNSNNRTIALRKRMQNHFMDSGNRNKSPSVHSNSC
KTNNKLKYTRRYSLDKLSHNMNVLHDYTVTHVQSQLTPTQFGLNDKRFPTYTCHYQPVDV
YTESSATQLSDSNLSDPHTGYNKAPVPFALTQYLELTKQAFMDHFAMLHSPAYASTIQSE
LEREHNRQAELLKHTKFLEQSIAKLHSDGTDLLNRFTKRLGILITTPAAFFSQARRLIKQ
HHVLEEKIAEFRRQISLLSSANQELVRRHHIEAARLLATATAIKSDNSFQNQHPTLNKLI
CSGNDVKVTEINKNGFHYNSDNMLPSSTSSESNYRNAISLNSVVIPPPPSLTKVSHNTLN
CNKFGIPSIATSDNLVSAHEMNQQHSLNPIKSSNIKLRTSNGAPSVLRNNTDVHRFAPVL
IKTVNTSNHSAVSVHTTNNKADRDHKVITDNSNNHNNTNNTTNNGTNHRIDKHMNIPPPP
PLLPMHIHSDVYVDGALSSAKSPTDFNKHKYCNSNNNPSLLPELNRSFITCRTDYDMSLI
QSNYRSHTKSMHASLQDLILDEFSRETPCISVSNCPTVTKTNKNRNVYSMSDSSYSCQYE
NNPDPLFQRHNHHNHNHKILHPNYIDYSHQLNLPPRKRHWDSSNYNPTTTNNYGEECEPP
KLSRECKSTDMET
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgtccgaaaatccaacactggttgagcttctcaaggaaacggacaggagctcctatgat
gatgtatcgaaactttgtgatgtgtacaataaagctatcatagatctttgggacatgtgg
attgaggaaaatactgtccctgaatttttcaaccgaaaagcttcccgtggtcatgttcag
ttcattcttcttcaatgttataatcgagctgtatcagatccggataaactgaatcaatat
ccacctttttcgcctcaagtgtatggggagacttccttcgaacttatttcacagatgatc
gacacgatcgcagttactagtgacgacgtatttatcgatcttgggagtggtgttggtcag
gttgtccttcaagtatgtgcctctactgatgcgaaattttgttacggaattgaaaaggct
gaatatcccgctaactgcgcatcgcgtcttgactcaactttccgtcactggatgagcttt
tacggaaagtcttatcgaccctacacgttggaacgcggagattttctatcagcggagtac
caagagaaaataacaaatgctggcgtcctttttgcaaacaactttgcctttggtccagag
gtggatcaccagctaaagcaaaggtttgctaaccttaaagaaggtgctcggataatctct
tcaaaggctttctgtcctttaaatttccgaatcactgataggaatctcggagatattgga
tcaatcatgcgtgtgagctgtttaaacccaatccaagatgcagtttcatggactgacaaa
ccatttagctattatgttcatacaattgatcgttcgctgttagaacaatactttgctcgt
ttaaaaaatccgaaatctaaaaatgaaaatcgaaccgttcgtcgcgatcgtaagggtcgt
gtaatttctgaggcaactatgcgagaaggttcaatccagttaacactaaatgctagcggt
aacaatcaacataacacaaatggtaacgtcagtcataaagctaagaggtcatcagctatc
ataaaacatcgttcgagtacttcccggtgcttaccaaataggtcagcatctctacctgca
gtaacagctagttctccttcagagttgatctctgttaaaggaagaaagctgagttcacaa
aattatttatcaaagaatgaaactattagtcgccaaatcactaatgggtccatggttgtg
catagaataaaacaatgtgaatcaccacatttacaatcagaacttaagcgttctcatgtt
caccataaagacaatcagtcacctcttgatatcttcacactatctaaggatactagtaat
gcaggtctagttgaatctcacgttgatacacaactagcgtcattaacttcaggtggaccg
atagcctgtgataataatgaagacaggaaacagtttcgtaaagttattcaacatttgtta
gatgatccttgcgaatctcactcattatcaaagtcagataatatcaaacagagtgtacgt
cgtaaaagcaaaacaattgaaaatgataacaagttaacatttaattatccaattattgat
gattacttaagtttacattcatcatcatgtcacgatcagcgcgatagtcggaattcttcg
tcatcaccgtatgtttcttcattatcgtcggctaatcgatctccgaattctcaaatcgat
gaaatcacttctttgaatagcttgacaaaacgttctgatctggaattaaaatcagttcaa
tcacctgatctttctattttcccagaaaataaactagataaggataaacatgaggattct
tttcatatacgtattaaattcaaaatatctaattcaccatgtggtcaaaaccatccagtc
agtgttaaaatcaaacctccatgtaatggtgataacacgcccaatagattaagtaatcct
gaaaactccaatgacacatgcgatactaatgtcataaataaggaccatcctaatagcgta
gctaatcgtcgtatacttcgtaaatgtcgacaaatgttaagtgatgattcatcatcatta
aatgttacaaattttaaaaattcaaacaatcgaacaatagccttgcgaaaacgaatgcaa
aatcactttatggattcgggaaaccgtaataaatccccatcagtgcattctaattcttgc
aaaacgaataacaaattaaaatatacacgtagatattcacttgataaattaagtcacaat
atgaatgttttacacgattacactgtaacacatgtgcaatcccaactaacaccaactcag
tttggattgaatgacaaaagatttcctacatacacatgtcattaccaacctgtggatgtg
tatacagaaagcagtgcaacccaactgagtgactcaaacttgtctgatcctcatacagga
tataataaagcaccggtaccgttcgcacttacacaatatttggaattgactaaacaagca
tttatggaccattttgccatgctacattcccccgcctacgcatcaacaattcaatcagaa
cttgaacgcgaacacaatcgacaagctgagttattaaaacacacaaaatttttggaacag
tctatcgctaaattgcattcagatgggacagatttattaaatcggttcacaaaacgccta
ggtatcctaatcaccacaccggctgcatttttctctcaagctcgaaggttaatcaaacag
catcatgttttggaggagaagattgctgaatttcgaaggcagatatcactactatcatct
gccaatcaagaattagtgagacgtcaccatattgaggctgcacgtcttttagccactgca
acagcgattaaatcagataattcatttcaaaatcaacatcctacattgaataagttaatc
tgctctggaaacgatgttaaagtaactgaaataaataaaaatggatttcattataattct
gacaatatgttaccatcttccacttcttctgaatcaaattatcgaaatgctatttcgctg
aactcagtagtgataccaccaccaccatcgttaactaaagtttctcataatacactaaac
tgcaataaattcggaatcccttcaattgccacttcagataacttagtatccgctcatgaa
atgaatcaacagcattcactgaatcctataaaatcttcaaatatcaagcttagaacatca
aacggtgcaccttcagttttgcgtaataatactgatgttcatagatttgcaccggtatta
ataaaaactgtgaatacaagtaaccattctgccgtttcagttcacactaccaataataag
gcagatcgcgatcataaagttattactgataatagtaataatcataacaacactaataat
accactaataacggcactaatcatagaattgataaacacatgaatatacctcctccacca
cctttactccctatgcacattcattcggatgtttatgtggatggtgcattatcatccgct
aaatctcccaccgatttcaacaaacataagtattgtaatagtaataataatccttcatta
ctccccgaactgaatcgttcatttattacatgtagaaccgattatgatatgtcacttatt
caatcaaattatcgttctcataccaaatcaatgcatgcttctctccaagatttaattctt
gatgagttctctcgtgaaacaccatgtatttcggtgagtaattgtcctactgttactaaa
actaataaaaacagaaatgtttacagtatgtcagattcttcatatagttgtcagtacgag
aataatccagatcccctttttcaacgtcacaaccaccacaatcataatcataaaattctt
catcctaattacatagattacagtcaccaattgaatttaccaccacgtaaacgacactgg
gattcatctaactacaatcctacaactactaataattatggtgaagagtgcgaacccccc
aaattgtctcgtgagtgtaagagtacagacatggagacctag
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