Streptomyces hygroscopicus subsp. jinggangensis 5008: SHJG_0276
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Entry
SHJG_0276 CDS
T02063
Name
(GenBank) cyclase
KO
K19969
2-epi-5-epi-valiolone synthase [EC:
4.2.3.152
]
Organism
shy
Streptomyces hygroscopicus subsp. jinggangensis 5008
Pathway
shy00525
Acarbose and validamycin biosynthesis
shy01100
Metabolic pathways
shy01110
Biosynthesis of secondary metabolites
Module
shy_M00815
Validamycin A biosynthesis, sedoheptulopyranose-7P => validamycin A
Brite
KEGG Orthology (KO) [BR:
shy00001
]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00525 Acarbose and validamycin biosynthesis
SHJG_0276
Enzymes [BR:
shy01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.3 Acting on phosphates
4.2.3.152 2-epi-5-epi-valiolone synthase
SHJG_0276
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GFIT
Motif
Pfam:
DHQ_synthase
DHQS_C
Fe-ADH_2
Fe-ADH
Motif
Other DBs
NCBI-ProteinID:
AEY85554
UniProt:
H2K887
Structure
PDB
PDBj
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Position
368721..369965
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AA seq
414 aa
AA seq
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MTMTKQSSLSPGSRLYDYTTQDGAAWRVSALKEVSYDVVVQPRLLDPANPALADALSSGT
TPARRLIVIDATVRSLYGEQLAAYLAGHDVEFHLCVIDAHESAKVMETVFEVVDAMDAFG
VPRRHAPVLAMGGGVLTDIVGLAASLYRRATPYVRIPTTLIGMIDAGIGAKTGVNFREHK
NRLGTYHPSSLTLIDPGFLATLDARHLRNGLAEILKVALVKDAELFDLLEGHGASLVEQR
MQPGEGGTGGAALTVLRRAVQGMLEELQPNLWEHQLRRLVDFGHSFSPSVEMAALPELLH
GEAVCIDMALSSVLAHHRGLLTEAELGRVLDVMRLLHLPVLHPVCTPDLMRAALADTVKH
RDGWQHMPLPRGIGDAVFVNDVTQREIEAALLTLAERDRVPRWRALHGAVDMGV
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgaccatgaccaagcagagttccttatcccccggtagccgcctgtacgactacaccacg
caggacggcgcggcctggcgggtgagcgcgctcaaggaggtgagctacgacgtcgtggtg
cagccgcggctgctcgatccggcgaatccggcgctcgccgacgccctctcgtccgggacg
acgcctgcgcgccggctcatcgtcatagacgctacggtgcgctccctctacggcgagcag
cttgccgcctacctggcgggccatgacgtggagttccacctgtgcgtcatcgacgcacac
gagtcggcaaaggtcatggagaccgtcttcgaagtcgtggacgcgatggacgccttcggt
gtgccacggcgccacgcgccggtgctcgccatgggtggcggggtgctcacggacatcgtc
ggtcttgcggcgagcctgtaccgcagggccacgccgtacgtccgcatacccacgaccctg
atcgggatgatcgacgcgggcatcggcgccaagacaggtgtcaacttccgtgagcacaag
aatcggttgggcacgtatcacccctcctcgctgaccctcatcgatcccggcttcctcgcc
acactcgacgcccgacacctgcgcaacggtctggcggaaatcctgaaggtagccctggtc
aaggatgccgaactgttcgatctgctggaggggcacggcgcgagcctggtcgagcagcgg
atgcaaccgggcgagggcgggacgggcggtgcggcgctcacagtgttgcgccgggcggtc
cagggcatgctggaggagctccagcccaatctctgggaacaccagctgcggcgcctggtg
gacttcggccactccttctcacccagcgtggagatggcggcgctgcccgagttgctgcac
ggcgaggccgtctgcatcgacatggcgctcagctcggtgctcgcccaccaccgtgggcta
ctgaccgaggccgagctcggccgtgtcctcgatgtcatgcgtctgctccacctgcctgta
cttcacccggtgtgcacgccggacctcatgcgcgcggcgctcgcggacacggtcaaacac
cgggacggctggcaacacatgccccttccacgcgggatcggcgacgccgtgttcgtgaac
gacgtcactcaacgggagatcgaggccgcgcttctcacactcgccgagcgggaccgggtg
ccgcggtggcgggcgctgcacggtgccgtggacatgggggtgtga
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