Streptomyces hygroscopicus subsp. jinggangensis 5008: SHJG_4106
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Entry
SHJG_4106 CDS
T02063
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
shy
Streptomyces hygroscopicus subsp. jinggangensis 5008
Pathway
shy00790
Folate biosynthesis
shy01100
Metabolic pathways
shy01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
shy00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SHJG_4106
Enzymes [BR:
shy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SHJG_4106
6.3.2.17 tetrahydrofolate synthase
SHJG_4106
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AEY89378
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Position
complement(4727500..4729014)
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AA seq
504 aa
AA seq
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MSEAPGTSDTPDPLDSFDEIIEAETTRDPDLAVIEAGSRTLRTQGGPAQADVPARPEDPE
VDKALREVEAELATRWGETKLEPSVSRIAALMDVLGEPQRSYPSIHITGTNGKTSTARMI
EALLGAFELRTGRYTSPHVQSITERISLDGAPITAERFIETYQDIKPYVEMVDGQQEYRL
SFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGETH
AQIAGEKSGIIKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVDRQVAVGGQ
LLTLRGLGGEYHEVYLPLHGAHQAHNAAVALAAVEAFFGVGAQRAEPLDIDTVRKAFAAV
SSPGRLEVVRRSPTVVLDAAHNPAGAEATAEAVREAFDFTRLIGVVGASGDKNVRGLLEA
FEPIFAEVVVTQNSSPRAMDADELAAIAVEVFGDERVQVEPRLPDALEAAITLAEEEGEF
AGGGVLVTGSVITVGEARLLLGKG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaagcgcccggcaccagcgacacccccgaccccctcgactccttcgacgagatc
atcgaggccgagaccacccgcgaccccgacctcgcggtcatcgaggccggcagccgcacc
ctgcgcacccagggcggccctgcgcaggcggacgtgcccgcccgccccgaggaccccgag
gtcgacaaggccctgcgcgaggtcgaggccgagctggccactcgctggggcgagacgaag
ctggagccctcggtcagccgcatcgccgcgctgatggacgtgctgggcgagccccagcgg
tcgtacccctcgatccacatcacgggcacgaacggcaagacctccaccgcccgcatgatc
gaggccctgctcggcgccttcgagctgcgcaccggccgctacaccagcccgcacgtgcag
tcgatcaccgagcggatcagcctggatggcgccccgatcaccgccgagcggttcatcgag
acgtaccaggacatcaagccgtacgtcgagatggtcgacgggcagcaggagtaccggctg
tccttcttcgaggtgctcaccggcatggcgtacgcggccttcgcggacgcccccgtggac
gtcgccgtcgtcgaggtcggcatgggcggctcctgggacgccaccaacgtgatcgacggc
gacgtcgccgtcgtcacccccatcgacctcgaccacaccgaccggctcggcgagacgcac
gcgcagatcgccggcgagaagagcggcatcatcaagcaggacgcgaccgtcatcctggcc
cagcagccggtggacgcggcgcaggtgctgctgaagaaggccgtggaggtcgacgccacc
gtggcccgtgaggggctggagttcggcgtcgtcgaccggcaggtcgccgtgggcgggcag
ctcctcacgctgcgcggcctcggcggcgagtaccacgaggtgtacctgccgctgcacggc
gcccaccaggcgcacaacgcggccgtcgcgctcgccgccgtggaggcgttcttcggcgtg
ggcgcgcagcgcgccgagccgctggacatcgacaccgtgcgcaaggcgttcgcggccgtg
tcgtccccgggccggctggaggtcgtacggcgctctcccaccgtcgtgctggacgccgcg
cacaaccccgccggtgccgaggccaccgccgaggccgtgcgggaggcgttcgacttcacc
cggctgatcggcgtcgtcggcgcgagcggcgacaagaacgtgcgcgggctgctggaggcc
ttcgagccgatcttcgcggaggtcgtcgtcacgcagaactccagccctcgcgccatggac
gcggacgagctggccgcgatcgccgtcgaggtgttcggcgacgagcgcgtgcaggtcgag
ccgcggctgccggacgccctggaggccgcgatcacgctggccgaggaggagggcgagttc
gcgggcggcggtgtgctggtgaccggttccgtcatcacggtcggcgaggcccggctgctg
ctggggaagggctga
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