Candidatus Sulfidibacterium hydrothermale: LA303_09720
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Entry
LA303_09720 CDS
T07944
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
shyr
Candidatus Sulfidibacterium hydrothermale
Pathway
shyr00260
Glycine, serine and threonine metabolism
shyr00261
Monobactam biosynthesis
shyr00270
Cysteine and methionine metabolism
shyr00300
Lysine biosynthesis
shyr01100
Metabolic pathways
shyr01110
Biosynthesis of secondary metabolites
shyr01120
Microbial metabolism in diverse environments
shyr01230
Biosynthesis of amino acids
Module
shyr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
shyr_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
shyr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LA303_09720 (thrA)
00270 Cysteine and methionine metabolism
LA303_09720 (thrA)
00300 Lysine biosynthesis
LA303_09720 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LA303_09720 (thrA)
Enzymes [BR:
shyr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LA303_09720 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LA303_09720 (thrA)
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SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
NAD_binding_3
ACT
ACT_6
DivIC
Motif
Other DBs
NCBI-ProteinID:
UBM61685
LinkDB
All DBs
Position
complement(2388903..2391353)
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AA seq
816 aa
AA seq
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MLVLKFGGSSVATAENVKRVIEIVRDKIKEEPSLIVVASAFGGITNLLDKSGEKARSGSE
EYKSFLATIETRHMTMIEGLFPFKNQGEIKASVKMILNELEDICFGIFLLQEMNRRVHDR
LLSFGERLSGKIISEAFRLQGIPINYQDARELIITEENWERIQVDFSETQKRIDRQLKNA
SFPVYVPGFIASTRSGIPSTLGRGGSDYTAALLAAMTGSRALEIWTDVDGVMTADPALVE
SAMPLSKLSYSELMEMSHFGAKVIFPPSIQPVMKKNIPVWIKNTFHPEVPGTLIDADGTE
NGHPVKGLSHIEGIVLLTITGGGMVGVTGTAARLFSCLSQQNVNVIFITQASSEHSITLA
VSQEDAEKATKAIENEFAAERKLGLIDRLLIENGLSIVALVGDKMKSSLGLSGKAFDALG
KNGINIRAIAQGSTEKNVSFVVKENDVVKTLNVLHERFFLSPFKKVHLFMVGVGNVGSAL
LEQIQRQYSCLKKEYALEIKVMAVANSRLMAFDDSGIELGNWKKQLAAQGTPMNKELFVQ
KMKAMNLRNSIFVDNTASHSIALLYEKILKASISVVASNKIAASGSYSTYKKLNDTALSM
KKKFLYETNVGAGLPVLKTIRDMRKSGDKIFRIQAVLSGSLNFIFNHFTGETPFSEIVKL
AREEGYTEPDPRIDLSGQDVMRKILILARESGYPLEPDEVSVVPFLPEHLMKADSVEKFM
EELEKQNNSLEKQRQKAEKNQKKLRYVAEFNRGKAQVGLQMVDPDQPYYQLDGKDNIVLI
FSQRYDEQPLVIKGAGAGAAVTASGVFADIISIVNQ
NT seq
2451 nt
NT seq
+upstream
nt +downstream
nt
atgctggttttaaaatttggcggaagctcggtagctacggccgaaaatgtgaaaagagtc
atagaaattgttcgtgataaaatcaaagaagaaccttcgttaattgttgtggcatcggca
tttggcggaattaccaatctccttgacaaaagtggagagaaggcccggagcggttcggaa
gaatataaatctttccttgccacgatagaaacccggcacatgacgatgatagaaggtctt
ttcccgtttaaaaatcagggagagataaaggcttccgtaaaaatgatcttgaatgaactc
gaagacatttgttttgggattttcttgttgcaggaaatgaaccggcgtgtccatgaccgg
ttgctctcttttggcgaaagattgtccggaaagattatttcagaagcttttcgtttacag
ggtattccaattaattatcaggatgcccgggaattgattatcacagaagaaaactgggaa
cgcatacaggttgatttttctgaaacccaaaagagaattgaccggcaactgaaaaatgct
tcctttccggtttatgttcccggttttattgcatcaacccggtcggggattcccagcacg
ttgggacgcggaggctctgattataccgccgctttactggctgcgatgaccggtagccgt
gcccttgaaatatggacagatgtggacggtgtgatgacagccgacccggcgttggtggaa
agtgccatgccgttatcgaaattgtcttacagcgaattgatggaaatgtcgcattttggg
gcaaaggttattttcccccccagtatccagccggtaatgaaaaaaaatatcccggtatgg
attaaaaatacatttcatccggaagttccgggaacattgattgatgcggatggaacggaa
aacggacatccggtaaaaggactttctcatattgaaggcattgtgttactcactattacg
ggtggaggaatggtcggtgttaccggaactgctgcacggcttttttcttgtttgtcacaa
caaaatgtaaacgttatttttattacacaggcatcgtcagagcattctattaccctggcc
gtcagtcaggaagatgcggagaaagccacaaaagccatcgaaaatgagtttgctgccgaa
cggaaattgggattaatagatcgtctgcttatagaaaacggcttgtcgattgttgctttg
gtgggcgataaaatgaaatcctctttgggattaagcggaaaagcgtttgatgccttaggg
aaaaacggaatcaatatccgggccatagcccaggggtctacagagaaaaatgtctctttt
gtggtaaaggaaaacgatgttgttaaaactttgaatgttttgcacgaacgtttctttttg
tctccttttaaaaaagttcacctgtttatggttggggttggaaatgtgggaagtgctttg
ttagagcaaattcagcgccagtattcctgtctgaaaaaagaatatgcattggaaataaaa
gtaatggcggtggccaacagccggctgatggcttttgatgattcgggaattgaattagga
aactggaaaaaacaactggcggcgcagggaactcctatgaacaaagaactttttgtacaa
aaaatgaaagccatgaacttgcgaaattccatttttgtggataataccgcaagtcattct
atcgccctgttgtacgaaaagatattgaaagcgagtatcagtgttgtggcttccaacaaa
atagcggcatccggttcctactcaacgtataaaaagctcaacgatactgcgttgtccatg
aaaaagaagttcctttacgaaaccaatgtgggagccggtttgccggttctgaaaaccatt
agggatatgcgtaaaagtggagacaagattttccggattcaagcggttttgtccggtagc
ctgaattttattttcaatcattttaccggagaaactcctttttcggaaattgtgaaactg
gcaagagaagaaggttataccgagcccgatccgcgtattgatttgagcggacaggatgtg
atgcggaaaattctgatccttgcacgcgaaagcggttatccgttagaaccggatgaggtt
tccgtggttccgtttttgccggagcatttaatgaaagccgattctgtggagaagtttatg
gaagagcttgaaaaacaaaacaatagcttggaaaagcaacgccaaaaggccgaaaaaaat
caaaaaaagctgcgttatgtggcggagtttaaccggggtaaagcacaagtaggacttcaa
atggttgatccggaccagccgtattatcagcttgacggaaaagataatatcgtccttatc
ttttcgcagcgttatgacgagcagccgctggtaataaaaggtgccggtgccggtgctgcc
gtgactgcttccggtgttttcgccgatattatttccatagtaaatcaataa
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