Candidatus Sulfidibacterium hydrothermale: LA303_12025
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Entry
LA303_12025 CDS
T07944
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
shyr
Candidatus Sulfidibacterium hydrothermale
Pathway
shyr00290
Valine, leucine and isoleucine biosynthesis
shyr00620
Pyruvate metabolism
shyr01100
Metabolic pathways
shyr01110
Biosynthesis of secondary metabolites
shyr01210
2-Oxocarboxylic acid metabolism
shyr01230
Biosynthesis of amino acids
Module
shyr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
shyr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
LA303_12025
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LA303_12025
Enzymes [BR:
shyr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
LA303_12025
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
UBM62114
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Position
complement(2928227..2929720)
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AA seq
497 aa
AA seq
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MSDKIIVFDTTLRDGEQVPGCQLNTVEKIEVAKALESLGVDVIEAGFPISSPGDFQSVVE
ISKAVSKPVICGLTRAIEKDIEVAAEALQYAKRKRIHTGIGTSPYHIKYKLNSTPDKILE
RAVAAVKYAKKFVEDVEFYAEDAGRSDNAYLAKVVEAVIAAGATVVNIPDTTGYCLPHEF
GEKIRYLMEHVSNVHKAVISTHCHNDLGMATANTIEGVLNGARQVEVTINGIGERAGNTS
LEEVVMILKSHKDLPLHTDINTKQIYKTSRLVSSLMNMPVQPNKAIVGRNAFAHSSGIHQ
DGVLKNRENYEIINPKDVGIKESSIELTARSGRAALKHRLKILGYSFARKELDKIYDRFL
ALADKKKDIKDDDLRALIGKATRKDHKIHLELLQVVCGKSAVPMATVQLKINDEIHSATA
SGNGPIDAAFTAVKQIIKRKVHLEEFLIQAITRGSDDLGKVHVQIENRGTLYYGFSASTD
IITGAVEAFVDAISKII
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacaaaattattgtttttgacaccacacttcgtgatggcgaacaagtacccggt
tgtcagctgaacaccgtggaaaaaattgaagtagccaaagctctcgaatctttgggggta
gatgtcattgaagccggatttcctatttccagccccggtgatttccagtcggtggtcgaa
atctctaaagcggtttccaaaccggtaatttgcggacttacccgtgccattgaaaaagat
attgaagtagcggcagaagcgttgcagtatgccaaacgaaaaagaatccataccggtatc
ggaacgtctccgtaccacattaaatacaagctgaattctaccccggataaaattctggaa
agggcagtggctgcggtgaaatatgccaagaagtttgtggaagatgtggagttttacgct
gaagatgccggacggagcgacaatgcttatcttgccaaagtggtggaagccgtgattgct
gccggtgctacggtggtaaatattccggatactaccggttattgtcttcctcatgaattt
ggcgaaaaaatccgttacctgatggagcatgtttcaaatgtgcacaaagcggtaatctct
acgcattgtcataacgatttggggatggcaaccgccaataccatcgaaggcgttttgaat
ggagcccggcaggtggaagttaccattaacggtattggagaacgggccggaaatacgtcg
ctcgaagaggtggtaatgattctgaaaagtcataaagatctgcctttgcatacagatatc
aataccaaacagatttataaaaccagccgtttggtttcgtcgctcatgaacatgccagta
caacccaacaaagccattgtaggacgtaatgcttttgctcattcgtctggaattcaccag
gatggcgtgttgaaaaaccgggaaaactatgagattattaatcctaaagatgtggggatc
aaagagtcgagtatcgagctgaccgcccggagtggccgtgctgcactaaaacaccgtttg
aaaattctcggttacagctttgcccgcaaagaactggataagatttatgatcgttttctg
gctttggcagataagaaaaaagacatcaaagatgatgatttacgggcactaatcgggaaa
gcaacccgtaaagaccacaaaattcatctggagcttttgcaggtggtgtgtggtaaatcg
gcggttccgatggctacagtccagctgaaaatcaatgacgagatccattcggctaccgct
tcaggaaacggtcctattgatgctgcttttacggcagtcaagcaaatcattaaacgcaag
gtgcatctcgaagagtttttaattcaggccattacccgtggtagtgacgatttgggtaaa
gtgcatgtgcaaattgaaaatcgtggaacactttactatggtttttcggccagtaccgat
attattaccggcgcagtagaagcttttgtagatgctatttcaaaaattatttaa
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