Streptococcus intermedius B196: SIR_0430
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Entry
SIR_0430 CDS
T02830
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sib
Streptococcus intermedius B196
Pathway
sib00300
Lysine biosynthesis
sib00550
Peptidoglycan biosynthesis
sib01100
Metabolic pathways
sib01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sib00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SIR_0430 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SIR_0430 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SIR_0430 (murF)
Enzymes [BR:
sib01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SIR_0430 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGU75804
UniProt:
T1ZC16
LinkDB
All DBs
Position
409770..411140
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AA seq
456 aa
AA seq
DB search
MQLTFYEVASVLKAKNDVHLFPDCTFRKAEFDSRLIGEGDLFLPLKGARDGHDFIATAFE
NGAVATLSEKELEGYPYILVDDVLAALQHLARYYLEKMKVDVFAVTGSNGKTTTKDMLAH
LLSMAYKTYKTQGNYNNEIGLPYTVLHMPDDTEKLVLEMGQDHMGDIHLLSTIAQPKVGI
VTLIGEAHLEFFKSRHEIAKGKLQIADGMKNGALLVVPADKIINDFLPSQQNVVRFGPDE
DICLTKLEERKDSLTFETNFLTSAIDLPVTGKYNATNAMVATYVALKEGVTEEAIQKAFL
TLELTRNRTEWKKAKNGADILSDVYNANPTAMRLILETFSTIPYNDNGRKLVVLADMKEL
GAESKQMHSAMITSLNPEILSEIFLYGEDMAALFSYAKEIFPLGRVHYFVKNAEKDQFPA
LVKAIKKVLQPADQVLIKGSNSMNLANLVEELENEV
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgcaattaacgttctatgaggtggcttctgttttgaaagccaaaaatgatgttcatcta
tttccagattgtacatttagaaaggcagaatttgacagccgattgattggagagggagat
ttatttctgcctcttaagggtgcgcgtgatgggcatgactttattgcgacagcatttgaa
aatggagctgtggcaaccttgtcagaaaaagaattggaaggctatccttatattttagta
gatgatgtattagcagcactgcagcatttggcacggtattatctggaaaagatgaaggta
gatgtttttgcagtcacaggttctaatggtaagacgacgaccaaagacatgctggctcac
ctcttgtcaatggcttataagacttacaaaacgcaaggaaactacaataatgaaattggt
cttccttatacggtcttgcatatgccagatgatactgaaaagttggttctggaaatgggg
caagatcacatgggggatattcatcttttatctactatcgctcagccaaaagtaggcata
gtgactttaattggagaagcacatctagaattttttaaaagccgtcatgaaattgcaaaa
ggaaagctacaaatcgctgacggtatgaaaaatggggctcttttagttgttccagcggac
aagattatcaatgactttttaccaagtcagcaaaatgttgttcgttttggtccagacgaa
gatatttgtctaacaaaattagaagaacgaaaagatagcttgacctttgagaccaacttt
ttaactagtgctattgaccttccagtaactggaaaatacaatgcgactaatgctatggtt
gcaacctatgtagctttaaaagaaggggtgacagaagaggccattcaaaaagctttttta
actcttgaattaacgcgaaatcgcactgaatggaaaaaagctaaaaatggagctgatatc
ctctcagatgtttataatgcgaatccaacagctatgcgtctgattttggaaactttttct
acaattccttataatgataatggtcggaagttggttgttttagctgatatgaaggagctg
ggggctgagtctaaacaaatgcatagcgctatgataactagtctaaatccggaaatttta
tcagaaatatttctctacggagaagatatggctgctctttttagctatgccaaggaaatt
ttcccgctagggagagtccactattttgtaaaaaatgctgaaaaagaccagtttccggcc
ttagtaaaagcgattaaaaaagtgctccaaccagcagatcaagtgttgataaaaggaagt
aactctatgaatttagctaatctagtagaggaattggagaatgaggtgtaa
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