Saccharolobus islandicus LAL14/1: SiL_0192
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Entry
SiL_0192 CDS
T02620
Name
(GenBank) Isopropylmalate/homocitrate/citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sic
Saccharolobus islandicus LAL14/1
Pathway
sic00290
Valine, leucine and isoleucine biosynthesis
sic00620
Pyruvate metabolism
sic01100
Metabolic pathways
sic01110
Biosynthesis of secondary metabolites
sic01210
2-Oxocarboxylic acid metabolism
sic01230
Biosynthesis of amino acids
Module
sic_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SiL_0192
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SiL_0192
Enzymes [BR:
sic01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SiL_0192
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AGJ61671
UniProt:
M9UAV9
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All DBs
Position
complement(165888..166931)
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AA seq
347 aa
AA seq
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MIARNLADLGVDVIEAGFPASSEGEFIATKKIFEEVGDQVEVIGLSRSNKNDIDKTISTG
ISSIHLFIATSELHMKYKLKMTKEEVLNKIYESVKYAKDHGMIVEFSPEDATRTEEDFLF
TAIRTAIEAGAERINIPDTVGTMHPFKYYDMIKKIVNFVGERIIVSVHCHNDFGLATANS
LAGVYAGARQAHVTVNGIGERAGNASLEEVVMGIKKLLNYETNVKTWKLYEVSRFVAEMT
GIPVPYFKAIVGDNAFGHESGIHVHGVIENPFTYEPISPEEVGNFRRLALGKHSGIHGLR
KLLEEQGIYLSEDKLKIVLAEIKKLAESGNKVTVEDAKNIALKLMNS
NT seq
1044 nt
NT seq
+upstream
nt +downstream
nt
atgatagctagaaatttagcagatctaggtgttgatgtaattgaagcaggttttcctgca
tcttcagaaggagaattcatagctactaaaaagattttcgaagaggtaggggatcaagta
gaagtaattggattatctagatccaataaaaacgatatagataagacaataagtactgga
atctcaagtatacacttattcatagccacttcagaattgcacatgaaatataaattaaag
atgacaaaagaggaagttctaaataagatctatgaaagcgtgaaatacgcaaaagatcac
ggtatgatagtggaatttagcccagaagacgcaacaagaactgaagaggacttcttgttc
acagcaattagaactgcaatagaagcaggggcagaaaggataaatataccagacacagta
ggaactatgcatcctttcaagtattacgatatgataaagaaaattgtaaacttcgtaggt
gagagaataatagtgagtgttcactgccataacgacttcggcttagcaacagcgaattca
ttagctggtgtatacgctggtgctagacaggctcacgttactgtaaatggtataggtgag
agagctgggaatgcatcactagaagaagtagtaatgggaataaagaaattactaaattat
gagacaaatgtgaaaacttggaaattgtatgaggtaagtaggtttgtggctgaaatgact
ggcataccagtgccctatttcaaggcaattgttggagataatgcctttggtcacgaatct
gggatacacgttcatggagtaatagaaaaccccttcacatatgagccaatttcgccagaa
gaagtaggtaatttcagaagattggcattaggcaagcacagtgggatacatggtttaagg
aaattattagaagaacaaggaatatacctatctgaagataaattaaagatagtcctagct
gagattaagaaattagctgaatctggtaataaggtaacagtggaagatgcgaaaaacatt
gcacttaaattgatgaattcttaa
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