Saccharolobus islandicus M.16.4: M164_2006
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Entry
M164_2006 CDS
T00906
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sid
Saccharolobus islandicus M.16.4
Pathway
sid00290
Valine, leucine and isoleucine biosynthesis
sid00620
Pyruvate metabolism
sid01100
Metabolic pathways
sid01110
Biosynthesis of secondary metabolites
sid01210
2-Oxocarboxylic acid metabolism
sid01230
Biosynthesis of amino acids
Module
sid_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sid00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
M164_2006
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
M164_2006
Enzymes [BR:
sid01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
M164_2006
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
Motif
Other DBs
NCBI-ProteinID:
ACR42609
UniProt:
C4KJ45
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All DBs
Position
1835341..1837002
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AA seq
553 aa
AA seq
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MVLKMKYDFFPLSLKLLNLPIIFHLCSVSKKSVEVLDTTLRDGSQGANISFTLNDKIKIA
LLLDELGVEYIEGGWPGSNPKDEEFFKEIKKYKLSKARIAAFGSTKRKDVSVKEDISLNS
IIKADVDFAVIFGKSWSLHATEVLKVTKQDNLDIIYDSINYLRSHGLKVIFDAEHFYQGF
KEDPKYALEVVKTAESAGADVIALADTNGGTPPFEVYEITKKVREVLHVKLGIHAHNDIG
CAVANSLMAIKAGARHVQGTINGIGERTGNADLIQIIPTLVLKMGFNVLKGRDSLRKLRE
VSRIVYEILGLPPNPYQPYVGDNAFAHKAGVHVDAVMKVPRAYEHVDPLLVGNDRKFVIS
ELSGTANLVSYLQGIGIVVDKKDERLKKALNKIKELEAKGYSFDVGPASAILITLKELNM
YTNYINLEYWKVINENNGLSIGIVKVNSQLEVAEGVGPVNAIDRALRMALQRVYPEIGEV
KLIDYRVILPSEVKNTESVVRVTIEFTDNKMNWRTEGVSKSVVEASVMALVDGLDYYLQL
KKTLKTSADNYIA
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atggtgctaaaaatgaaatatgattttttcccattatcattaaagcttttaaatcttccc
attatttttcacctatgttcggtgtccaagaaatctgttgaggttctagatacaacatta
agagatggatcgcagggcgcgaatatatcttttactctaaatgataaaattaagatagca
ttactcttagatgagcttggagtagaatatattgaaggaggatggccaggatctaatcct
aaggatgaggagttctttaaagagataaagaaatataaactatctaaagctagaatagct
gcctttggaagtaccaaaagaaaagatgttagcgtaaaggaagatattagtctaaatagt
ataataaaagcagatgttgattttgctgtaatatttggtaagtcatggtcactacatgct
actgaagtcctaaaggtaactaagcaagataatttagatataatatatgacagcattaat
tatttgagatcacatggtcttaaggtgatatttgatgcagagcacttctatcaaggcttt
aaagaagatccaaaatatgcactcgaagtagtgaaaactgcagaatctgcgggggcagat
gtaattgctttagcagatactaatggtggtacaccaccatttgaggtttatgagataaca
aagaaagttagagaagtattacatgttaaactaggtattcatgcccataatgatatagga
tgtgcagttgccaactctttaatggctataaaagcaggagctaggcatgtccaaggaaca
ataaatggaattggcgagagaactggtaatgctgatctaatacagataatacccacatta
gtgttaaaaatgggatttaatgtattaaaaggtagagatagtttaaggaaattgagggag
gtttcaagaatagtatatgaaatactaggattacctcctaatccctatcaaccttatgtt
ggtgataacgccttcgcacacaaagctggtgttcatgttgatgctgtaatgaaggtaccc
agagcgtatgaacatgttgatcctttattagtaggtaatgacagaaagtttgtaatttca
gaattgtctggaactgcaaatctagtctcatatttacaaggcataggaatagttgttgac
aagaaagacgaaaggcttaaaaaagctttaaataagattaaggaacttgaggctaaagga
tatagttttgatgttggtccagcttccgcaattttgataacactaaaggagctaaacatg
tatacgaattatataaatttagaatactggaaagtaataaacgagaataatggtctttca
atagggatcgttaaagttaattctcagctcgaagttgctgaaggggtaggtccagtaaac
gcaatagatagagcgctaagaatggcacttcagcgggtatatccagaaataggtgaagtt
aagttaatagattatagggttatattgcctagtgaagttaagaacactgagagtgtcgtt
agggttaccatagaatttacagataataaaatgaactggagaacagaaggagtatctaaa
agcgttgtggaagcttcagtcatggcattagtagatgggcttgattattacctacaatta
aagaagacattaaaaacaagtgcagataattatattgcgtga
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