Streptococcus intermedius JTH08: SCIM_1162
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Entry
SCIM_1162 CDS
T02156
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sie
Streptococcus intermedius JTH08
Pathway
sie00300
Lysine biosynthesis
sie00550
Peptidoglycan biosynthesis
sie01100
Metabolic pathways
sie01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sie00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SCIM_1162 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SCIM_1162 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SCIM_1162 (murF)
Enzymes [BR:
sie01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SCIM_1162 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAM23816
LinkDB
All DBs
Position
complement(1332972..1334342)
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AA seq
456 aa
AA seq
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MQLTFYEVASVLKAKNDVHLFPDYTFRKAEFDSRLIGEGDLFLPLKGARDGHDFIATAFE
NGAVATLSEKELEDYPYILVDDVLAALQHLARYYLEKMKVDVFAVTGSNGKTTTKDMLAH
LLSMAYETYKTQGNYNNEIGLPYTVLHMPDDTEKLVLEMGQDHMGDIHLLSTIAQPKVGI
VTLIGEAHLEFFKSRHEIAKGKLQIADGMKNGALLVVPADKIINDFLPSQQNVVRFGPDE
DICLTKLEERKDSLTFETNFLTSAIDLPVTGKYNAANAMVATYVALKEGVTEEAIQKAFL
TLELTRNRTEWKKAKNGADILSDVYNANPTAMRLILETFSTIPYNDNGRKLVVLADMKEL
GAESKQMHSAMITSLNPEILSEIFLYGEDMAALFSYAKEIFPLGRVHYFVKNAEKDQFPA
LVKAIKKVLQPADQVLIKGSNSMNLANLVEELENEV
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgcaattaacgttctatgaggtggcttctgttttgaaagccaaaaatgatgttcatcta
tttccagattatacatttagaaaggcagaatttgacagccgattgattggagagggagat
ttatttctgcctcttaagggtgcgcgtgatgggcatgactttattgcgacagcatttgaa
aatggagctgtggcaaccttatcagaaaaagaattggaagactatccttatattttagta
gatgatgtattagcagcactgcagcatttggcacggtattatctggaaaagatgaaggta
gatgtttttgcagtcacaggttctaatggtaagacgacgaccaaagacatgctggctcac
ctcttgtcaatggcttatgagacttacaaaacgcaaggaaactacaataatgaaattggt
cttccttatacggtcttgcatatgccagatgatactgaaaagttggtgctggaaatgggg
caagatcacatgggggatattcatcttttatctactatcgctcagccaaaagtaggcata
gtgactttaattggagaagcacatctagaattttttaaaagccgtcatgaaattgcaaaa
ggaaagctacaaatcgctgacggtatgaaaaatggggctcttttagttgtcccagcggac
aagattatcaatgactttttaccaagtcagcaaaatgttgttcgttttggtccagacgaa
gatatttgtctaacaaaattagaagaacgaaaagatagcttgacctttgagaccaacttt
ttaactagtgctattgaccttccagtaactggaaaatacaatgcggctaatgctatggtt
gcaacctatgtagctttaaaagaaggggtgacagaagaggccattcaaaaagcttttttg
actcttgaattaacgcgaaatcgcactgaatggaaaaaagctaaaaatggagctgatatc
ctctcagatgtttataatgcgaatccaacagctatgcgtctgattttggaaactttttct
acaattccttataatgataatggtcggaagttggttgttttagctgatatgaaggagctg
ggggctgagtctaaacaaatgcatagcgctatgataactagtctaaatccggaaatttta
tcagaaatatttctctacggagaagatatggctgctctttttagctatgccaaggaaatt
ttcccgctagggagagtccactattttgtaaaaaatgctgaaaaagaccagtttccggcc
ttagtaaaagcgattaaaaaagtgctccaaccagcagatcaagtgttgataaaaggaagt
aactctatgaatttagctaatctagtagaggaattggagaatgaggtgtaa
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