Streptococcus ilei I-G2: N596_00735
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Entry
N596_00735 CDS
T02879
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sig
Streptococcus ilei I-G2
Pathway
sig00300
Lysine biosynthesis
sig00550
Peptidoglycan biosynthesis
sig01100
Metabolic pathways
sig01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sig00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
N596_00735
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
N596_00735
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
N596_00735
Enzymes [BR:
sig01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
N596_00735
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Cellulase
Motif
Other DBs
NCBI-GeneID:
17315383
NCBI-ProteinID:
AGY39359
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Position
117262..118632
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AA seq
456 aa
AA seq
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MNVTLHEVARVLAIRNDISQFEDFDLQKPEFDSRLIGPGDLFVPLKGARDGHDFIETAFE
NGAVATLSEKEVEGHPYLLVDDVLGAFQKLAQYVLEKSQVDVLAVTGSNGKTTTKDMLAQ
LLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSEIAHPKAAI
VTLIGEAHLEFFKDRTEIAKGKLQIADGMPAGGLLLVPADPIVEDFLPNQQELVRFGEGA
DIRITKLEERKDSLTFEANFLSDAIDLPVTGKYNATNAMIAAYVALKEGVSEEAIRASFK
GLELTKNRTEWKKASNGADILSDVYNANPTAMRLILETFSTIPANPNGRKLAVLADMKEL
GEQSIDLHNQMILSLSPDVLDTVIFYGQDIAGLAQLASQMFPLGHVYYFKKTAEKDQFED
LVKQVKESLKEQDQILIKGSNSMNLAKLVEELENGE
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaatgtaaccttgcacgaagtggctcgtgtcctggctattcgcaatgatatcagtcaa
tttgaagattttgatttacagaagccagaatttgatagtcgtcttattggtccgggggac
ctctttgtccctctcaagggggcgcgtgatgggcatgattttattgaaaccgcctttgaa
aatggggctgtagcgaccttgtctgaaaaagaagtagaaggccacccgtatttgttggta
gatgatgttctaggggcctttcaaaaattagctcaatatgttttggagaagagtcaagta
gatgtcttggcggtcacaggttcaaacggtaagacaacgaccaaagatatgttagctcag
ttattatctactacttataaaacctataaaacacaagggaactacaataacgagattggc
cttccttacacggttctccatatgccagaaggaacagagaagcttgtccttgaaatggga
caggaccatctgggagatatccatctcctctcagaaattgcccatcctaaggcagcaatc
gtgaccctcattggggaagctcacttggagtttttcaaagatcgcacagaaatcgctaaa
gggaaattgcaaattgcggacggtatgccagctggtggcttgctcctagtaccggccgat
cccattgtagaggattttttacccaaccaacaagagcttgtgcgctttggtgaaggagca
gatatccgcattaccaagttggaggaacgcaaggacagcctaacctttgaagcgaatttc
ttatcagatgctattgacttacctgtcacaggcaaatacaatgcgaccaatgccatgatt
gcggcctatgttgccttgaaagaaggagtcagtgaagaggccatccgtgcaagctttaaa
ggcttagagcttactaagaaccgtacagaatggaagaaggcaagtaacggagcggatatc
ctatccgatgtctacaatgccaatccgacggccatgcgcctgattttagaaaccttctcg
accattcctgccaatccaaatggccgcaagctagcggtcttagcggatatgaaagaacta
ggggagcaatctattgatctgcacaaccaaatgattctcagcctgtcaccggatgtcttg
gataccgttattttctacggtcaagatattgcgggactggctcaattagcgagtcagatg
ttcccactcggacatgtctattatttcaaaaagaccgctgagaaagaccagtttgaggac
ctggtcaaacaagtcaaggaaagcttaaaagagcaggaccaaatcctcatcaagggaagc
aattctatgaatttagccaaattggtagaggagttggagaatggcgagtaa
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