Saccharolobus islandicus M.16.27: M1627_2077
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Entry
M1627_2077 CDS
T00900
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sim
Saccharolobus islandicus M.16.27
Pathway
sim00290
Valine, leucine and isoleucine biosynthesis
sim00620
Pyruvate metabolism
sim01100
Metabolic pathways
sim01110
Biosynthesis of secondary metabolites
sim01210
2-Oxocarboxylic acid metabolism
sim01230
Biosynthesis of amino acids
Module
sim_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sim00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
M1627_2077
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
M1627_2077
Enzymes [BR:
sim01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
M1627_2077
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
Motif
Other DBs
NCBI-ProteinID:
ACP55944
UniProt:
C3N004
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All DBs
Position
1935103..1936764
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AA seq
553 aa
AA seq
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MALKMKYDFFPLSLKLLNLPIIFHLCSVSKKSVEVLDTTLRDGSQGANISFTLNDKIKIA
LLLDELGVEYIEGGWPGSNPKDEEFFKEIKKYKLSKARIAAFGSTKRKDVSVKEDISLNS
IIKADVDFAVIFGKSWSLHATEVLKVTKQDNLDIIYDSINYLRSHGLKVIFDAEHFYQGF
KEDPKYALEVVKTAESAGADVIALADTNGGTPPFEVYEITKKVREVLHVKLGIHAHNDIG
CAVANSLMAIKAGARHVQGTINGIGERTGNADLIQIIPTLVLKMGFNVLKGRDSLRKLRE
VSRIVYEILGLPPNPYQPYVGDNAFAHKAGVHVDAVMKVPRAYEHVDPLLVGNDRKFVIS
ELSGTANLVSYLQGIGIVVDKKDERLKKALNKIKELEAKGYSFDVGPASAILITLKELNM
YTNYINLEYWKVINENNGLSIGIVKVNSQLEVAEGVGPVNAIDRALRMALQRVYPEIGEV
KLIDYRVILPSEVKNTESVVRVTIEFTDNKMNWRTEGVSKSVVEASVMALVDGLDYYLQL
KKTLKTSADNYIA
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atggcgctaaaaatgaaatatgattttttcccattatcattaaagcttttaaatcttccc
attatttttcacctatgttcggtgtccaagaaatctgttgaggttctagatacaacatta
agagatggatcgcagggcgcgaatatatcttttactctaaatgataaaattaagatagca
ttactcttagatgagcttggagtagaatatattgaaggaggatggccaggatctaatcct
aaggatgaggagttctttaaagagataaagaaatataaactatctaaagctagaatagct
gcctttggaagtaccaaaagaaaagatgttagcgtaaaggaagatattagtctaaatagt
ataataaaagcagatgttgattttgctgtaatatttggtaagtcatggtcactacatgct
actgaagtcctaaaggtaactaagcaagataatttagatataatatatgacagcattaat
tatttgagatcacatggtcttaaggtgatatttgatgcagagcacttctatcaaggcttt
aaagaagatccaaaatatgcactcgaagtagtgaaaactgcagaatctgcgggggcagat
gtaattgctttagcagatactaatggtggtacaccaccatttgaggtttatgagataaca
aagaaagttagagaagtattacatgttaaactaggtattcatgcccataatgatatagga
tgtgcagttgccaactctttaatggctataaaagcaggagctaggcatgtccaaggaaca
ataaatggaattggcgagagaactggtaatgctgatctaatacagataatacccacatta
gtgttaaaaatgggatttaatgtattaaaaggtagagatagtttaaggaaattgagggag
gtttcaagaatagtatatgaaatactaggattacctcctaatccctatcaaccttatgtt
ggtgataacgccttcgcacacaaagctggtgttcatgttgatgctgtaatgaaggtaccc
agagcgtatgaacatgttgatcctttattagtaggtaatgacagaaagtttgtaatttca
gaattgtctggaactgcaaatctagtctcatatttacaaggcataggaatagttgttgac
aagaaagacgaaaggcttaaaaaagctttaaataagattaaggaacttgaggctaaagga
tatagttttgatgttggtccagcttccgcaattttgataacactaaaggagctaaacatg
tatacgaattatataaatttagaatactggaaagtaataaacgagaataatggtctttca
atagggatcgttaaagttaattctcagctcgaagttgctgaaggggtaggtccagtaaac
gcaatagatagagcgctaagaatggcacttcagcgggtatatccagaaataggtgaagtt
aagttaatagattatagggttatattgcctagtgaagttaagaacactgagagtgtcgtt
agggttaccatagaatttacagataataaaatgaactggagaacagaaggagtatctaaa
agcgttgtggaagcttcagtcatggcattagtagatgggcttgattattacctacaatta
aagaagacattaaaaacaagtgcagataattatattgcgtga
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