Streptomyces inhibens: KI385_26070
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Entry
KI385_26070 CDS
T08140
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sine
Streptomyces inhibens
Pathway
sine00290
Valine, leucine and isoleucine biosynthesis
sine00770
Pantothenate and CoA biosynthesis
sine01100
Metabolic pathways
sine01110
Biosynthesis of secondary metabolites
sine01210
2-Oxocarboxylic acid metabolism
sine01230
Biosynthesis of amino acids
Module
sine_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sine_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sine00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KI385_26070 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
KI385_26070 (ilvD)
Enzymes [BR:
sine01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
KI385_26070 (ilvD)
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
UKY51937
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Position
5702385..5704235
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AA seq
616 aa
AA seq
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MPDLRSRTVTHGRNMAGARALMRASGVASEDIGKPIIAVANSFTEFVPGHTHLAPVGRIV
SDAIRDAGAVPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICIS
NCDKITPGMLMAAMRLNIPVVFVSGGPMEAGQATLVDGTVRKLDLINAIVDSVNDNVSDE
DVLRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARRALYENAGRTV
VEITKRYYEDGDESVLPRNIATHAAFENAMALDIAMGGSTNTILHLLAAAQEAELDYGLR
DMDAISRRVPCLAKVAPNVAPGGTYYMEDVHRAGGIPAILGELYRGGLLNEDVHSVHSTS
LAEHLKTWDVRGGSPSAEAVELWHAAPGCKRSATAFSQSERWESLDVDAEGGCIRSVEHA
YSKDGGLAVLKGNIAEDGCVVKTAGVDESIWTFEGPAVVCESQEEAVDKILTKQVKEGDV
VVIRYEGPKGGPGMQEMLYPTSFLKGRGLGKACALVTDGRFSGGTSGLSIGHASPEAASG
GTIALVEDGDRIRIDIPNRSIELLVGEEELAARREALGGVYAPKQRERKVSQALRAYAAM
ATSADKGAVRDVSKLG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
gtgcccgatctgaggtctcgcaccgttacccatggccgcaacatggcgggcgcccgcgcc
cttatgcgggcctcgggtgtagcgagcgaggacatcggtaagccgatcatcgcggtggcc
aactccttcaccgagttcgtgcccgggcacacccacctcgccccggtcggccggatcgtc
tccgacgccatccgggacgccggcgccgtaccgcgcgagttcaacaccatcgcggtcgac
gacggcatcgccatgggccacggcggcatgctctactcgctcccctcccgcgacctgatc
gcggactcggtcgagtacatggtcgaggcgcactgcgccgacgcgctgatctgtatctcc
aactgcgacaagatcacccccggcatgctgatggccgcgatgcgcctcaacatcccggtc
gtcttcgtctccggcggcccgatggaggccggccaggccaccctcgtggacggcacggtc
cgcaagctggacctgatcaacgccatcgtcgactccgtcaacgacaacgtctccgacgag
gacgtcctccgcatcgaggagaacgcctgccccacctgcggttcctgctccggcatgttc
accgccaactcgatgaactgcctcaccgaggccatcggcctgtccctgccgggcaacggc
tcggtgctcgccacccacaccgcccgccgcgccctgtacgagaacgccggccgtacggtc
gtggagatcaccaagcgctactacgaggacggcgacgagtccgtcctgccgcgcaacatc
gccacccacgccgccttcgagaacgccatggcgctcgacatcgcgatgggcggctccacc
aacaccatcctgcatctgctcgccgccgcccaggaggccgagctcgactacggcctccgg
gacatggacgcgatctcgcgccgggtcccctgcctggccaaggtcgccccgaacgtggcc
cccggcggcacgtactacatggaggacgtgcaccgcgccggtggcatccccgccatcctc
ggcgagctctaccgcggcggactgctcaacgaggacgtgcactccgtccactccacctcg
ctcgcggagcacctcaagacctgggacgtgcgcggcggttcaccgtccgccgaggccgtc
gagctgtggcacgcggcccccggctgcaagcgctcggccaccgccttctcgcagtccgag
cgctgggagtcgctggacgtggacgccgagggcggctgcatccgctccgtcgagcacgcc
tactccaaggacggcggcctcgcggtcctcaagggcaacatcgccgaggacggctgcgtc
gtgaagaccgcgggcgtcgacgagtccatctggaccttcgagggcccggccgtggtctgc
gaatcccaggaagaggccgtcgacaagatcctcaccaagcaggtcaaggagggcgacgtc
gtcgtcatccgctacgagggccccaagggcggccccggcatgcaggagatgctctacccg
acgtccttcctcaagggccgcggcctgggcaaggcctgcgcactggtcaccgacggccgc
ttctccggcggcacgtccggcctctccatcggccatgcctcgcccgaggcggcgtccggc
ggcaccatcgccctcgtcgaggacggcgaccggatccgtatcgacatccccaaccgctcg
atcgaactcctcgtcggcgaggaggagttggcggcccgccgcgaggccctcggcggcgtc
tacgcgcccaagcagcgcgagcgcaaggtctcgcaggcgctgcgcgcgtacgcggcgatg
gcaaccagcgcggacaagggcgcggtgcgcgatgtgagcaagctcggctga
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