Streptococcus iniae ISET0901: DQ08_02920
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Entry
DQ08_02920 CDS
T03285
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
siq
Streptococcus iniae ISET0901
Pathway
siq00300
Lysine biosynthesis
siq00550
Peptidoglycan biosynthesis
siq01100
Metabolic pathways
siq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
siq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DQ08_02920
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DQ08_02920
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DQ08_02920
Enzymes [BR:
siq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DQ08_02920
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Lant_dehydr_N
Motif
Other DBs
NCBI-ProteinID:
AHY15432
UniProt:
A0A3L8GN77
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All DBs
Position
572506..573885
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AA seq
459 aa
AA seq
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MKLTLHEIAKVVDAENAISEFEDVPLGQIEFDSRKITKGDLFLPLKGLRDGHDFIDIAFE
NGAVATFSEKVISNKPYILVKDTLVAFQKLAQYYIEKMRLDVIAVTGSNGKTSTKDMIEA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHLGDIHLLSEIAKPHIAV
VTLIGEAHLEFFGSRDKIAEGKMQITDGMDSDGILIAPGDAIIDPYLPDNQMIIRFGPHQ
EIFVEDVVEEKTGLTFTTNVLKEKVKLPLAGKFNASNAMVAAYVGKLLAVTDEDIIEALE
TVSLTKNRTEWLKAANGADILSDVYNANPTATRLILESFSSISANPNGKKIALLADMKEL
GEDSVALHSQLVSSLNPNLITDLVFYGDDIEELAQLASQIYPINKVHFFRKDKEIDQFEA
LCQHVKALVESTDQILLKGSNSMNLERLVDALVTTRSSR
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacattacatgaaatagcgaaggttgtggatgcagaaaatgccatctcagag
tttgaagacgttcccctgggacaaatcgaatttgatagcagaaaaatcactaaaggggac
ctttttttgcccttaaaaggcttacgagatgggcatgattttattgatattgcctttgaa
aatggtgctgtggcaaccttctcagagaaagtaattagtaacaagccttatattttagtg
aaagacaccttagtggctttccaaaaattagctcagtattatattgaaaaaatgcgtctc
gacgttattgcagtgactggctcaaatggtaaaaccagtacaaaggacatgattgaggct
gtgctttcaaccacttataaaacctataaaacacaaggtaactataataatgaaattggc
ttgccttatacggtactgcatatgcctgatgatacagaaaaaattgtcctagaaatggga
caagaccatttgggtgatattcatctcttatcagaaattgccaagcctcacattgcagtt
gtaaccttaatcggtgaagcccatttagaattttttggcagtcgagataagattgcagaa
ggcaaaatgcaaatcacagatggtatggattcagacggcattttaattgccccaggtgat
gcaatcattgatccttatcttccagacaatcaaatgattatccgttttggaccgcatcag
gagatttttgttgaagatgttgtggaagaaaaaactggattaaccttcacaactaatgtg
cttaaagagaaggtcaaacttcctttggcaggtaaatttaatgccagtaatgctatggta
gcagcctatgttggtaaactattagctgtaactgatgaagacattattgaagcattagag
acggtctctttaaccaaaaatcgtacagaatggttgaaagctgctaatggagcagatata
ttatcagatgtctacaatgccaatccaacagcgacacgattgattttagaaagtttttct
agcatttcagcaaatcctaatgggaaaaaaatagccctattagctgatatgaaagaatta
ggagaagactcagtagctcttcactcacaattagtcagttctttgaatcctaaccttatt
actgaccttgttttttatggagacgatattgaagagttggcgcaattagccagtcaaatc
taccccattaataaagtgcatttctttagaaaagataaggagattgatcaatttgaagcc
ctttgccaacatgttaaggcattagttgaatcaactgatcaaatcttacttaaaggaagt
aactcaatgaaccttgagcgacttgttgatgctttagtgacaacaagatcatcacgatag
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