Saccharolobus islandicus REY15A: SiRe_0199
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Entry
SiRe_0199 CDS
T01953
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sir
Saccharolobus islandicus REY15A
Pathway
sir00290
Valine, leucine and isoleucine biosynthesis
sir00620
Pyruvate metabolism
sir01100
Metabolic pathways
sir01110
Biosynthesis of secondary metabolites
sir01210
2-Oxocarboxylic acid metabolism
sir01230
Biosynthesis of amino acids
Module
sir_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SiRe_0199
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SiRe_0199
Enzymes [BR:
sir01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SiRe_0199
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ADX84294
UniProt:
F0NBE7
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All DBs
Position
complement(175439..176482)
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AA seq
347 aa
AA seq
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MIARNLADLGVDVIEAGFPASSEGEFIATKKIFEEVGDQVEVIGLSRSNKNDIDKTISTG
ISSIHLFIATSELHMKYKLKMTKEEVLNKIYESVKYAKDHGMIVEFSPEDATRTEEDFLF
TAIRTAIEAGAERINIPDTVGTMHPFKYYDMIKKIVNFVGERIIVSVHCHNDFGLATANS
LAGVYAGARQAHVTVNGIGERAGNASLEEVVMGIKKLLNYETNVKTWKLYEVSRFVAEMT
GIPVPYFKAIVGDNAFGHESGIHVHGVIENPFTYEPISPEEVGNFRRLALGKHSGIHGLR
KLLEEQGIYLSEDKLKIVLAEIKKLAESGNKVTVEDAKNIALKLMNS
NT seq
1044 nt
NT seq
+upstream
nt +downstream
nt
atgatagctagaaatttagcagatctaggtgttgatgtaattgaagcaggttttcctgca
tcttcagaaggagaattcatagctactaaaaagattttcgaagaggtaggggatcaagta
gaagtaattggattatctagatccaataaaaacgatatagataagacaataagtactgga
atctcaagtatacacttattcatagccacttcagaattgcacatgaaatataaattaaag
atgacaaaagaggaagttctaaataagatctatgaaagcgtgaaatacgcaaaagatcac
ggtatgatagtggaatttagcccagaagacgcaacaagaactgaagaggacttcttgttc
acagcaattagaactgcaatagaagcaggggcagaaaggataaatataccagacacagta
ggaactatgcatcctttcaagtattacgatatgataaagaaaattgtaaacttcgtaggt
gagagaataatagtgagtgttcactgccataacgacttcggcttagcaacagcgaattca
ttagctggtgtatacgctggtgctagacaggctcacgttactgtaaatggtataggtgag
agagctgggaatgcatcactagaagaagtagtaatgggaataaagaaattactaaattat
gagacaaatgtgaaaacttggaaattgtatgaggtaagtaggtttgtggctgaaatgact
ggcataccagtgccctatttcaaggcaattgttggagataatgcctttggtcacgaatct
gggatacacgttcatggagtaatagaaaaccccttcacatatgagccaatttcgccagaa
gaagtaggtaatttcagaagattggcattaggcaagcacagtgggatacatggtttaagg
aaattattagaagaacaaggaatatacctatctgaagataaattaaagatagtcctagct
gagattaagaaattagctgaatctggtaataaggtaacagtggaagatgcgaaaaacatt
gcacttaaattgatgaattcttaa
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