Saccharolobus islandicus REY15A: SiRe_1872
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Entry
SiRe_1872 CDS
T01953
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sir
Saccharolobus islandicus REY15A
Pathway
sir00290
Valine, leucine and isoleucine biosynthesis
sir00620
Pyruvate metabolism
sir01100
Metabolic pathways
sir01110
Biosynthesis of secondary metabolites
sir01210
2-Oxocarboxylic acid metabolism
sir01230
Biosynthesis of amino acids
Module
sir_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SiRe_1872
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SiRe_1872
Enzymes [BR:
sir01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SiRe_1872
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
Motif
Other DBs
NCBI-ProteinID:
ADX85934
UniProt:
F0NI50
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All DBs
Position
1728990..1730639
Genome browser
AA seq
549 aa
AA seq
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MKYDFFPLSLKLLNLPIIFHLCSVSKKSVEVLDTTLRDGSQGANISFTLNDKIKIALLLD
ELGVEYIEGGWPGSNPKDEEFFKEIKKYKLSKARIAAFGSTKRKDVSVKEDISLNSIIKA
DVDFAVIFGKSWSLHATEVLKVTKQDNLDIIYDSINYLRSHGLKVIFDAEHFYQGFKEDP
KYALEVVKTAESAGADVIALADTNGGTPPFEVYEITKKVREVLHVKLGIHAHNDIGCAVA
NSLMAIKAGARHVQGTINGIGERTGNADLIQIIPTLVLKMGFNVLKGRDSLRKLREVSRI
VYEILGLPPNPYQPYVGDNAFAHKAGVHVDAVMKVPRAYEHVDPLLVGNDRKFVISELSG
TANLVSYLQGIGIVVDKKDERLKKALNKIKELEAKGYSFDVGPASAILITLKELNMYTNY
INLEYWKVINENNGLSIGIVKVNSQLEVAEGVGPVNAIDRALRMALQRVYPEIGEVKLID
YRVILPSEVKNTESVVRVTIEFTDNKMNWRTEGVSKSVVEASVMALVDGLDYYLQLKKTL
KTSADNYIA
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
atgaaatatgattttttcccattatcattaaagcttttaaatcttcccattatttttcac
ctatgttcggtgtccaagaaatctgttgaggttctagatacaacattaagagatggatcg
cagggcgcgaatatatcttttactctaaatgataaaattaagatagcactactcttagat
gagcttggagtagaatatattgaaggaggatggccaggatctaatcctaaggatgaggag
ttctttaaagagataaagaaatataaactatctaaagctagaatagctgcctttggaagt
accaaaagaaaagatgttagcgtaaaggaagatattagtctaaatagtataataaaagca
gatgttgattttgctgtaatatttggtaagtcatggtcactacatgctactgaagtccta
aaggtaactaagcaagataatttagatataatatatgacagcattaattatttgagatca
catggtcttaaggtgatatttgatgcagagcacttctatcaaggctttaaagaagatcca
aaatatgcactcgaagtagtgaaaactgcagaatctgcgggggcagatgtaattgcttta
gcagatactaatggtggtacaccaccatttgaggtttatgagataacaaagaaagttaga
gaagtattacatgttaaactaggtattcatgcccataatgatataggatgtgcagttgcc
aactctttaatggctataaaagcaggagctaggcatgtccaaggaacaataaatggaatt
ggcgagagaactggtaatgctgatctaatacagataatacccacactagtgttaaaaatg
ggatttaatgtattaaaaggtagagatagtttaaggaaattgagggaggtttcaagaata
gtatatgaaatactaggattacctcctaatccctatcaaccttatgttggtgataatgcc
ttcgcacacaaagctggtgttcatgttgatgctgtaatgaaggtacccagagcgtatgaa
catgttgatcctttattagtaggtaatgacagaaagtttgtaatttcagaattgtctgga
actgcaaatctagtctcatatttacaaggcataggaatagttgttgacaagaaagacgaa
aggcttaaaaaagctttaaataagattaaggaacttgaggctaaaggatatagttttgat
gttggtccagcttccgcaattttgataacactaaaggagctaaacatgtatacgaattat
ataaatttagaatactggaaagtaataaacgagaataatggtctttcaatagggatcgtt
aaagttaattctcagctcgaagttgctgaaggggtaggtccagtaaacgcaatagataga
gcgctaagaatggcacttcagcgggtatatccagaaataggtgaagttaagttaatagat
tatagggttatattgcctagtgaagttaagaacactgagagtgtcgttagggttaccata
gaatttacagataataaaatgaactggagaacagaaggagtatctaaaagcgttgtggaa
gcttcagtcatggcattagtagatgggcttgattattacctacaattaaagaagacatta
aaaacaagtgcagataattatattgcgtga
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