Streptomyces kanamyceticus: CP970_12410
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Entry
CP970_12410 CDS
T06849
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ska
Streptomyces kanamyceticus
Pathway
ska00290
Valine, leucine and isoleucine biosynthesis
ska00660
C5-Branched dibasic acid metabolism
ska01100
Metabolic pathways
ska01110
Biosynthesis of secondary metabolites
ska01210
2-Oxocarboxylic acid metabolism
ska01230
Biosynthesis of amino acids
Module
ska_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ska00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CP970_12410 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CP970_12410 (leuC)
Enzymes [BR:
ska01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CP970_12410 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CP970_12410 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QEU91581
UniProt:
A0A5J6GCL0
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Position
complement(3075052..3076476)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLYIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMARPKTMAITVDGELPDGVTA
KDLILAIIAKIGTGGGQGYVLEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
DYIQGRAHAPQGADWDAAVAYWKTLRTDDDAVFDAEVYIDATALAPFVTWGTNPGQGAPL
SANVPDPASYEDASERHAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAAAS
VVEGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVTGHLAAPTDLSDAPVTAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctctacatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggcctccgccaggcaggccgcccggtgcggcggctcgacctcaccatcgcgacc
gaggatcacaacaccccgaccctcgacatcgacaagcccatcgccgacccggtctcgcgc
gcccagctggagacgctgcgcaagaactgcgccgagttcggggtgcgcctgcacccgctg
ggcgacgtcgagcagggcgtcgtccacgtggtgggaccgcagctgggactgacccagccc
ggcaccaccgtggtctgcggcgactcgcacacctccacccacggcgcgttcggcgccctg
gcgttcggcatcggcacctcccaggtcgagcacgtcctggccacccagacgctgccgatg
gcccgcccgaagaccatggccatcacggtcgacggcgaactgcccgacggcgtcaccgcc
aaggacctcatcctcgccatcatcgcgaagatcggcaccggcggcggccagggctacgtc
ctggagtaccgcggcccggccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggcgggcgcccgcgcgggcatgatcgccccggacgagaccacgttc
gactacatccagggccgcgcccacgccccgcagggcgctgactgggacgccgcggtggcg
tactggaagaccctgcggaccgatgacgacgcggtcttcgacgccgaggtctacatcgac
gccaccgcgctcgcgccgttcgtcacctggggcaccaaccccggccagggagcgcccctt
tcggcgaacgtccccgacccggcttcgtacgaagacgcttcggagcggcacgccgccgaa
aaggccctggagtacatggggttgaccgccgggcagccgctgcgcgacatcaaggtcgac
accgtcttcgtaggttcctgcaccaatggccgcatcgaggacctgcgggcggcggcctcc
gtcgtcgagggccgcaaagtcgccgacggcgtacggatgctggtcgtgcccggctcggtc
cgggtcgccctgcaggccgtcgaggagggcctggacaaggtcttcaccgccgcgggggcc
gaatggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccaactggccccc
ggcgagcgctcggcgtccacctccaaccgcaacttcgagggcaggcagggcaagggcggc
cgcacccacctggtctccccgcaggtcgccgccgccaccgcggtcaccggccacctggcc
gcgcccaccgatctgtccgacgcccccgtgaccgccggagtctga
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